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The map label for this gene is gltA [H]

Identifier: 138894954

GI number: 138894954

Start: 1374314

End: 1378873

Strand: Direct

Name: gltA [H]

Synonym: GTNG_1292

Alternate gene names: 138894954

Gene position: 1374314-1378873 (Clockwise)

Preceding gene: 138894952

Following gene: 138894955

Centisome position: 38.71

GC content: 52.83

Gene sequence:

>4560_bases
ATGAAGCACTACGGATTGCCAGAAGCACAAGGATTGTATCGACCGGAATTTGAACATGATGCATGCGGGATCGGGTTTTA
TGCTCATTTAAAAGGAAAACCGTCACATGACATTATTGAAAAAGCGCTCCATATGCTTCGCCGGCTCGAACACCGGGGCG
GTCAAGGCAGCGATCCGGAAACTGGCGACGGCGCGGGCATTATGATGCAAATTCCGCACGAGTACTTTCAAATCGTGTGC
GGCGAAATGAACTTACCGGAAAAAGGTCGCTACGGGGTCGGGATGCTCTTTTTGCCGGAAAATGAAGAAAAACGAGCGTA
CTATGAAGCAAAATTCAATGAAATTATTGCTCAGGAAGGGCAGCAGTTGCTCGGATGGCGAACGGTGCCGGTTGACAACA
GCAAGCTTGGCAAACTGGCGCAGCAAAGCAAACCGTTCATTCGCCAAGTGTTTGTCGCTGCTAGCGATGACATTTCCGAT
GAGTTGGCGTTTGAACGAAAATTGTATGTCATTCGCAAGCAATTTGAAAAGTGCGTCGAAAACAATGAGTGCTACGTAGC
GAGTTTCTCAAGCCGGACGATCGTTTATAAAGGGCTTTTGACTCCGGAACAAATCGACGCATTTTACTTGGATTTGCAAG
ATGAACGGTTCCGCTCGGCGTTTGCGCTTGTGCACTCGCGTTTTAGCACGAACACGTTTCCGAGCTGGGAGCGGGCTCAT
CCCAACCGCTATTTGATCCATAACGGTGAGATTAATACGCTTCGCGGCAACGTCAACTGGATGGCAGCGCGTGAAAAGCA
GTTTGTTTCAGAAGCGTTCGGTGCCGATTTGGAAAAAGTGACACCGATTTTGGATACAAACGGAAGTGACTCGTCGATTT
TGGACAATGCGTTTGAATTTTTTGTCTTGGCAGGCCGTAATCCAGCTCATGTGGCAATGATGCTCATTCCGGAACCGTGG
TTTTGGGATGAACAAATGGATGACATGAAAAAGGCGTTTTACGAGTATCATAGCTGTTTGATGGAGCCATGGGACGGCCC
GACGGCGATTTCATTCACTGACGGCAAGCGGATCGGCGCCATTTTGGACCGGAACGGATTGCGCCCGGCGCGCTACTATG
TGACGAAAGACGACTACATTATTTTCTCATCCGAAGTCGGCGTCATCGAGGTTGACCCGAACAACGTTTTGTATAAAGAG
CGGCTGAGCCCTGGAAAAATGTTGCTTGTTGATCTGGAACAAGGCCGGATCATTTCTGATCAGGAAATTAAGGAAGAAAT
GGCGAGCCAACAGCCGTATCGTCAATGGATTGATGAGCAAATGGTGACGCTTGATGATTTCAACGTTCCGGAAACGGTTG
AAGCGCCGAAATCGCTCATTAAGCTGCAAAAAGCATTCGGCTACACGTTTGAAGATGTAGAAAAAATGATTTTACCGATG
GCGAGGGAGGGCAAAGACCCGACGGGTGCGATGGGGATGGACGCGCCACTGGCGGTGCTGTCGGAGCGGCCGCAAAGCTT
GTTTAACTACTTCAAGCAACTGTTTGCTCAAGTAACGAACCCGCCGATTGACGCGATTCGCGAGTATGTCGTTACCTCGA
CAATGACGCTGCTTGGCAAAGAGGGGAACATTTTGCATCCGGATGCTAAAGCGGCGCGCCGCATTCGCCTTGAGACGCCG
TTGTTGACGAATGAGCAATTAGCCGCGTTAAAAGCGAATCCGTATCCAGAATTTTCGTGTGCCGTGTTGCCAACGCTGTT
TACGGATGACTTGAAACAAGCGCTTGACGAGCTGTTTGCCAAGGCGGATGAAGCGGTTGAAAACGGAGCGACGCTTCTTG
TTCTCTCGGATCGCGGCGTTGATGAAATGCATGTGGCAATTCCGGTGTTGCTTGCGGTGAGCGGGCTTCATCAGCACCTG
ATTCGAAAAGGGACGCGGACGAACGTCAGCCTGCTTGTCGAAAGCGGCGAAGCGCGCGAAGTGCACCATTTTGCGGCGCT
CATCGGTTACGGTGCTGACGCCATCAACCCGTATTTGGCGCTTGAGACGATCCGCCAGGCGTCAGAAAACGGCACGATCG
CCCTGTCGTATCGTGAAGCGGTAAAAACATATATGAAAGCGGCAGTCGACGGCGTCGTCAAAGTGATGTCGAAAATGGGA
ATTTCGACCGTGCAAAGCTACCGTGGCGCACAAATTTTTGAAGCGGTTGGTATTGGCACGGATGTCATCGACCAATATTT
CACTGGTACGGCGTCGCAAATTAGCGGCATCGGGCTTGACGAAATCGCCAAGGAAGCAAAATTGCGCCATGAAGCGGCAT
TTGGCGCCCGGCACGAAGACAACGTGCTTGAGGCTGGCAGCGAGCTGCAATGGCGACGCAACGGCGAGCACCATGCGTTC
AATCCGCAGACGATTCACTTGCTGCAATGGGCATGCCGGAAAAATGATTACAATCTCTATAAACAATATTCGAAACTGGC
CAATGAAGAACAGCTGACATTCTTGCGCAACTTGTTCGACTTCGATCCGAACCGGAAACCGGTGCCGATTGACGAGGTCG
AGCCGGTCAAGTCGATCGTCCGCCGTTTCAAAACAGGGGCGATGTCGTTTGGCTCGATCAGCCAAGAAGCGCACGAGGCG
CTCGCCATCGCCATGAACCGGATCGGTGGAAAAAGCAACAGTGGTGAGGGGGGCGAAGACCCGGCCCGCTATGTGAAAGA
CGAAAACGGTGACTGGCGCCGCAGCGCGATTAAACAGGTCGCTTCCGGGCGTTTTGGCGTGAAAAGCCATTACTTAGTCA
ACGCTGACGAATTGCAAATTAAAATGGCTCAAGGAGCAAAGCCGGGTGAAGGCGGCCAGCTTCCAGCCAATAAAGTGTAC
CCGTGGGTCGGCAAAGTGCGCGGCTCGACGCCGGGAGTGGAGCTCATTTCTCCGCCGCCGCATCATGACATTTACTCGAT
CGAAGATTTGGCTCAGCTCATTTATGACTTGAAAAACGCAAACAAACACGCGCGCATTAGTGTCAAGCTTGTCGCCAAAG
CAGGTGTCGGCACGATCGCCGCTGGCGTAGCGAAAGGGAATGCTGATGTTATCGTCATCAGCGGTTATGACGGCGGCACG
GGCGCTTCCCCGAAAACGAGCATTAAACATGCCGGCTTGCCGTGGGAGCTTGGCTTGGCGGAAACGCATCAAACGTTGAT
GCTTAACGGCTTGCGTGATCGTGTCATCTTGGAAACTGATGGAAAACTCATGACGGGACGCGATGTCGTGATGGCTGCGC
TGTTTGGCGCCGAAGAGTTCGGATTTGCGACGGCACCGCTCGTTGTTTTAGGCTGTGTCATGATGCGTGTCTGCCATTTA
GATACATGTCCGGTCGGTGTAGCGACACAAAATCCGGAGCTGCGCAAAAAGTTTATGGGTGATCCGGACCATGTTGTCAA
CTTCATGTACTTTGTCGCCCAGGAAGTGCGTGAAATTATGGCTGAACTTGGCTTCCGTACGATCGACGAAATGGTTGGCC
GCGTCGATGTCCTGAAAGTGAGCGAGCGGGCGAAAGCGCATTGGAAAGCGAAACATCTCGATTTGTCTCGCCTTCTGTAC
CAAGTGGACGGTCCGCGCACTTGTGGTAAGGGGCAAAACCATCGTTTGGAAACGACGCTTGACTATAAAGAAATTTTGCC
AGCAGTACAGCCAGCACTCGAGCGACAAGAGCCGGTTGAACTCAAGCTCGCGATCCACAACGTCCACCGCACGGTCGGGG
CGATGACGGGGGGCGAAATCTCGAAGCGCTACGGTGAAGAAGGGTTGCCGGAAGATACGATCCGCCTCCATTTCACGGGA
TCAGCCGGACAAAGCTTTGCGGCGTTTGCGCCGAAAGGAATGACGCTCGAGCTTGTCGGTGACGCAAATGACTACGTCGG
CAAAGGGCTCTCCGGCGGAAAAGTGATCGTCCGTCCGCCGCATGAGGCGTCGTTTGCGGCGGCAGATAACGTCATTATCG
GTAACGTCGCCTTCTACGGTGCAACAGGTGGCGAGGCGTATATTCGCGGCCGCGCCGGCGAGCGGTTTGCGGTGCGCAAC
AGTGGCGTCCATGCTGTTGTCGAAGGCGTCGGTGACCATGGTTGTGAATATATGACCGGCGGCCGTGTTGTTATCCTCGG
CTCGGTCGGCAAAAACTTCGCTGCCGGTATGTCAGGGGGGATCGCCTACGTCCTCGCTGATGAAGACAGCTGGCAACAAA
CAGCCAACCGAGAGCTCGTGGCGTTTGAATGGCTCGAAGACGAGCAAGAAATTTTGGAAGTGAGCCGGATGATCGAAAAC
CATTACCGCTATACAGGAAGCCCGCGGGCGGCGTTGGTACTTGACGAGTGGAACGCCTATGTGAAGCGGTTTGTCAAAGT
GATCCCGCGCAACTACAAACTGATGATTGAAACAATTCAAATGCTTGAACGGTCTGGGCTTTCGTATGAAGAAGCGGCCA
TGGCGGCGTTTGAAACGGTGGCGAAACAGAAAAAAGCGGCTGCCGCCAGCCCCCATGTATTGCAAGTGGCCGCAAAATAA

Upstream 100 bases:

>100_bases
AAAAATGAGATTGATTTCATCTAAATTATATATTGTTTATATAAATTTTGAAAACTACAATAAATATTACAGACAATTCG
GAACGGGAGGGGAAGGCAGC

Downstream 100 bases:

>100_bases
GGCCATCCTTTTGGGCGGCAGCAGCCATGGCGCCGCCTTGGCCCCGCGGCCCGCGCGGGGCTCGCTTTTTGACTGGCCAA
ACAGGCGGGGAAGGTCGCAT

Product: glutamate synthase large subunit

Products: NA

Alternate protein names: NADPH-GOGAT [H]

Number of amino acids: Translated: 1519; Mature: 1519

Protein sequence:

>1519_residues
MKHYGLPEAQGLYRPEFEHDACGIGFYAHLKGKPSHDIIEKALHMLRRLEHRGGQGSDPETGDGAGIMMQIPHEYFQIVC
GEMNLPEKGRYGVGMLFLPENEEKRAYYEAKFNEIIAQEGQQLLGWRTVPVDNSKLGKLAQQSKPFIRQVFVAASDDISD
ELAFERKLYVIRKQFEKCVENNECYVASFSSRTIVYKGLLTPEQIDAFYLDLQDERFRSAFALVHSRFSTNTFPSWERAH
PNRYLIHNGEINTLRGNVNWMAAREKQFVSEAFGADLEKVTPILDTNGSDSSILDNAFEFFVLAGRNPAHVAMMLIPEPW
FWDEQMDDMKKAFYEYHSCLMEPWDGPTAISFTDGKRIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVDPNNVLYKE
RLSPGKMLLVDLEQGRIISDQEIKEEMASQQPYRQWIDEQMVTLDDFNVPETVEAPKSLIKLQKAFGYTFEDVEKMILPM
AREGKDPTGAMGMDAPLAVLSERPQSLFNYFKQLFAQVTNPPIDAIREYVVTSTMTLLGKEGNILHPDAKAARRIRLETP
LLTNEQLAALKANPYPEFSCAVLPTLFTDDLKQALDELFAKADEAVENGATLLVLSDRGVDEMHVAIPVLLAVSGLHQHL
IRKGTRTNVSLLVESGEAREVHHFAALIGYGADAINPYLALETIRQASENGTIALSYREAVKTYMKAAVDGVVKVMSKMG
ISTVQSYRGAQIFEAVGIGTDVIDQYFTGTASQISGIGLDEIAKEAKLRHEAAFGARHEDNVLEAGSELQWRRNGEHHAF
NPQTIHLLQWACRKNDYNLYKQYSKLANEEQLTFLRNLFDFDPNRKPVPIDEVEPVKSIVRRFKTGAMSFGSISQEAHEA
LAIAMNRIGGKSNSGEGGEDPARYVKDENGDWRRSAIKQVASGRFGVKSHYLVNADELQIKMAQGAKPGEGGQLPANKVY
PWVGKVRGSTPGVELISPPPHHDIYSIEDLAQLIYDLKNANKHARISVKLVAKAGVGTIAAGVAKGNADVIVISGYDGGT
GASPKTSIKHAGLPWELGLAETHQTLMLNGLRDRVILETDGKLMTGRDVVMAALFGAEEFGFATAPLVVLGCVMMRVCHL
DTCPVGVATQNPELRKKFMGDPDHVVNFMYFVAQEVREIMAELGFRTIDEMVGRVDVLKVSERAKAHWKAKHLDLSRLLY
QVDGPRTCGKGQNHRLETTLDYKEILPAVQPALERQEPVELKLAIHNVHRTVGAMTGGEISKRYGEEGLPEDTIRLHFTG
SAGQSFAAFAPKGMTLELVGDANDYVGKGLSGGKVIVRPPHEASFAAADNVIIGNVAFYGATGGEAYIRGRAGERFAVRN
SGVHAVVEGVGDHGCEYMTGGRVVILGSVGKNFAAGMSGGIAYVLADEDSWQQTANRELVAFEWLEDEQEILEVSRMIEN
HYRYTGSPRAALVLDEWNAYVKRFVKVIPRNYKLMIETIQMLERSGLSYEEAAMAAFETVAKQKKAAAASPHVLQVAAK

Sequences:

>Translated_1519_residues
MKHYGLPEAQGLYRPEFEHDACGIGFYAHLKGKPSHDIIEKALHMLRRLEHRGGQGSDPETGDGAGIMMQIPHEYFQIVC
GEMNLPEKGRYGVGMLFLPENEEKRAYYEAKFNEIIAQEGQQLLGWRTVPVDNSKLGKLAQQSKPFIRQVFVAASDDISD
ELAFERKLYVIRKQFEKCVENNECYVASFSSRTIVYKGLLTPEQIDAFYLDLQDERFRSAFALVHSRFSTNTFPSWERAH
PNRYLIHNGEINTLRGNVNWMAAREKQFVSEAFGADLEKVTPILDTNGSDSSILDNAFEFFVLAGRNPAHVAMMLIPEPW
FWDEQMDDMKKAFYEYHSCLMEPWDGPTAISFTDGKRIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVDPNNVLYKE
RLSPGKMLLVDLEQGRIISDQEIKEEMASQQPYRQWIDEQMVTLDDFNVPETVEAPKSLIKLQKAFGYTFEDVEKMILPM
AREGKDPTGAMGMDAPLAVLSERPQSLFNYFKQLFAQVTNPPIDAIREYVVTSTMTLLGKEGNILHPDAKAARRIRLETP
LLTNEQLAALKANPYPEFSCAVLPTLFTDDLKQALDELFAKADEAVENGATLLVLSDRGVDEMHVAIPVLLAVSGLHQHL
IRKGTRTNVSLLVESGEAREVHHFAALIGYGADAINPYLALETIRQASENGTIALSYREAVKTYMKAAVDGVVKVMSKMG
ISTVQSYRGAQIFEAVGIGTDVIDQYFTGTASQISGIGLDEIAKEAKLRHEAAFGARHEDNVLEAGSELQWRRNGEHHAF
NPQTIHLLQWACRKNDYNLYKQYSKLANEEQLTFLRNLFDFDPNRKPVPIDEVEPVKSIVRRFKTGAMSFGSISQEAHEA
LAIAMNRIGGKSNSGEGGEDPARYVKDENGDWRRSAIKQVASGRFGVKSHYLVNADELQIKMAQGAKPGEGGQLPANKVY
PWVGKVRGSTPGVELISPPPHHDIYSIEDLAQLIYDLKNANKHARISVKLVAKAGVGTIAAGVAKGNADVIVISGYDGGT
GASPKTSIKHAGLPWELGLAETHQTLMLNGLRDRVILETDGKLMTGRDVVMAALFGAEEFGFATAPLVVLGCVMMRVCHL
DTCPVGVATQNPELRKKFMGDPDHVVNFMYFVAQEVREIMAELGFRTIDEMVGRVDVLKVSERAKAHWKAKHLDLSRLLY
QVDGPRTCGKGQNHRLETTLDYKEILPAVQPALERQEPVELKLAIHNVHRTVGAMTGGEISKRYGEEGLPEDTIRLHFTG
SAGQSFAAFAPKGMTLELVGDANDYVGKGLSGGKVIVRPPHEASFAAADNVIIGNVAFYGATGGEAYIRGRAGERFAVRN
SGVHAVVEGVGDHGCEYMTGGRVVILGSVGKNFAAGMSGGIAYVLADEDSWQQTANRELVAFEWLEDEQEILEVSRMIEN
HYRYTGSPRAALVLDEWNAYVKRFVKVIPRNYKLMIETIQMLERSGLSYEEAAMAAFETVAKQKKAAAASPHVLQVAAK
>Mature_1519_residues
MKHYGLPEAQGLYRPEFEHDACGIGFYAHLKGKPSHDIIEKALHMLRRLEHRGGQGSDPETGDGAGIMMQIPHEYFQIVC
GEMNLPEKGRYGVGMLFLPENEEKRAYYEAKFNEIIAQEGQQLLGWRTVPVDNSKLGKLAQQSKPFIRQVFVAASDDISD
ELAFERKLYVIRKQFEKCVENNECYVASFSSRTIVYKGLLTPEQIDAFYLDLQDERFRSAFALVHSRFSTNTFPSWERAH
PNRYLIHNGEINTLRGNVNWMAAREKQFVSEAFGADLEKVTPILDTNGSDSSILDNAFEFFVLAGRNPAHVAMMLIPEPW
FWDEQMDDMKKAFYEYHSCLMEPWDGPTAISFTDGKRIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVDPNNVLYKE
RLSPGKMLLVDLEQGRIISDQEIKEEMASQQPYRQWIDEQMVTLDDFNVPETVEAPKSLIKLQKAFGYTFEDVEKMILPM
AREGKDPTGAMGMDAPLAVLSERPQSLFNYFKQLFAQVTNPPIDAIREYVVTSTMTLLGKEGNILHPDAKAARRIRLETP
LLTNEQLAALKANPYPEFSCAVLPTLFTDDLKQALDELFAKADEAVENGATLLVLSDRGVDEMHVAIPVLLAVSGLHQHL
IRKGTRTNVSLLVESGEAREVHHFAALIGYGADAINPYLALETIRQASENGTIALSYREAVKTYMKAAVDGVVKVMSKMG
ISTVQSYRGAQIFEAVGIGTDVIDQYFTGTASQISGIGLDEIAKEAKLRHEAAFGARHEDNVLEAGSELQWRRNGEHHAF
NPQTIHLLQWACRKNDYNLYKQYSKLANEEQLTFLRNLFDFDPNRKPVPIDEVEPVKSIVRRFKTGAMSFGSISQEAHEA
LAIAMNRIGGKSNSGEGGEDPARYVKDENGDWRRSAIKQVASGRFGVKSHYLVNADELQIKMAQGAKPGEGGQLPANKVY
PWVGKVRGSTPGVELISPPPHHDIYSIEDLAQLIYDLKNANKHARISVKLVAKAGVGTIAAGVAKGNADVIVISGYDGGT
GASPKTSIKHAGLPWELGLAETHQTLMLNGLRDRVILETDGKLMTGRDVVMAALFGAEEFGFATAPLVVLGCVMMRVCHL
DTCPVGVATQNPELRKKFMGDPDHVVNFMYFVAQEVREIMAELGFRTIDEMVGRVDVLKVSERAKAHWKAKHLDLSRLLY
QVDGPRTCGKGQNHRLETTLDYKEILPAVQPALERQEPVELKLAIHNVHRTVGAMTGGEISKRYGEEGLPEDTIRLHFTG
SAGQSFAAFAPKGMTLELVGDANDYVGKGLSGGKVIVRPPHEASFAAADNVIIGNVAFYGATGGEAYIRGRAGERFAVRN
SGVHAVVEGVGDHGCEYMTGGRVVILGSVGKNFAAGMSGGIAYVLADEDSWQQTANRELVAFEWLEDEQEILEVSRMIEN
HYRYTGSPRAALVLDEWNAYVKRFVKVIPRNYKLMIETIQMLERSGLSYEEAAMAAFETVAKQKKAAAASPHVLQVAAK

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=1477, Percent_Identity=44.008124576845, Blast_Score=1218, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570289, Length=1524, Percent_Identity=47.50656167979, Blast_Score=1336, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320030, Length=1525, Percent_Identity=47.2131147540984, Blast_Score=1348, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574881, Length=1502, Percent_Identity=49.4007989347537, Blast_Score=1387, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665539, Length=1502, Percent_Identity=49.4007989347537, Blast_Score=1387, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665547, Length=371, Percent_Identity=49.5956873315364, Blast_Score=342, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24665543, Length=371, Percent_Identity=49.5956873315364, Blast_Score=342, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR002932
- InterPro:   IPR006982
- InterPro:   IPR002489 [H]

Pfam domain/function: PF00310 GATase_2; PF04898 Glu_syn_central; PF01645 Glu_synthase; PF01493 GXGXG [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 168555; Mature: 168555

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHYGLPEAQGLYRPEFEHDACGIGFYAHLKGKPSHDIIEKALHMLRRLEHRGGQGSDPE
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
TGDGAGIMMQIPHEYFQIVCGEMNLPEKGRYGVGMLFLPENEEKRAYYEAKFNEIIAQEG
CCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
QQLLGWRTVPVDNSKLGKLAQQSKPFIRQVFVAASDDISDELAFERKLYVIRKQFEKCVE
HHHHCEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
NNECYVASFSSRTIVYKGLLTPEQIDAFYLDLQDERFRSAFALVHSRFSTNTFPSWERAH
CCCEEEEEECCCEEEEEECCCHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCC
PNRYLIHNGEINTLRGNVNWMAAREKQFVSEAFGADLEKVTPILDTNGSDSSILDNAFEF
CCEEEEECCCEEEEECCCEEEHHHHHHHHHHHHCCCHHHCCCHHCCCCCCHHHHHHCEEE
FVLAGRNPAHVAMMLIPEPWFWDEQMDDMKKAFYEYHSCLMEPWDGPTAISFTDGKRIGA
EEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHH
ILDRNGLRPARYYVTKDDYIIFSSEVGVIEVDPNNVLYKERLSPGKMLLVDLEQGRIISD
HHCCCCCCCEEEEEECCCEEEEECCCCEEEECCCCEEECCCCCCCCEEEEECCCCCEECH
QEIKEEMASQQPYRQWIDEQMVTLDDFNVPETVEAPKSLIKLQKAFGYTFEDVEKMILPM
HHHHHHHHCCCHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AREGKDPTGAMGMDAPLAVLSERPQSLFNYFKQLFAQVTNPPIDAIREYVVTSTMTLLGK
HHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
EGNILHPDAKAARRIRLETPLLTNEQLAALKANPYPEFSCAVLPTLFTDDLKQALDELFA
CCCEECCCHHHHHEEEECCCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KADEAVENGATLLVLSDRGVDEMHVAIPVLLAVSGLHQHLIRKGTRTNVSLLVESGEARE
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHH
VHHFAALIGYGADAINPYLALETIRQASENGTIALSYREAVKTYMKAAVDGVVKVMSKMG
HHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
ISTVQSYRGAQIFEAVGIGTDVIDQYFTGTASQISGIGLDEIAKEAKLRHEAAFGARHED
HHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
NVLEAGSELQWRRNGEHHAFNPQTIHLLQWACRKNDYNLYKQYSKLANEEQLTFLRNLFD
HHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHH
FDPNRKPVPIDEVEPVKSIVRRFKTGAMSFGSISQEAHEALAIAMNRIGGKSNSGEGGED
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PARYVKDENGDWRRSAIKQVASGRFGVKSHYLVNADELQIKMAQGAKPGEGGQLPANKVY
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEECHHHEEEEEECCCCCCCCCCCCCCCCC
PWVGKVRGSTPGVELISPPPHHDIYSIEDLAQLIYDLKNANKHARISVKLVAKAGVGTIA
CCHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHH
AGVAKGNADVIVISGYDGGTGASPKTSIKHAGLPWELGLAETHQTLMLNGLRDRVILETD
HHHCCCCCCEEEEECCCCCCCCCCCCCHHCCCCCEECCHHHHHHHHHHCCCCCEEEEECC
GKLMTGRDVVMAALFGAEEFGFATAPLVVLGCVMMRVCHLDTCPVGVATQNPELRKKFMG
CCEECCHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCC
DPDHVVNFMYFVAQEVREIMAELGFRTIDEMVGRVDVLKVSERAKAHWKAKHLDLSRLLY
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCHHHHHH
QVDGPRTCGKGQNHRLETTLDYKEILPAVQPALERQEPVELKLAIHNVHRTVGAMTGGEI
HCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCHH
SKRYGEEGLPEDTIRLHFTGSAGQSFAAFAPKGMTLELVGDANDYVGKGLSGGKVIVRPP
HHHHCCCCCCCCCEEEEEECCCCCCCHHCCCCCCEEEEECCCCHHHCCCCCCCEEEEECC
HEASFAAADNVIIGNVAFYGATGGEAYIRGRAGERFAVRNSGVHAVVEGVGDHGCEYMTG
CCCCHHCCCCEEEECEEEEECCCCCEEEECCCCCEEEEECCCCHHHHHCCCCCCCCEECC
GRVVILGSVGKNFAAGMSGGIAYVLADEDSWQQTANRELVAFEWLEDEQEILEVSRMIEN
CEEEEEECCCCCHHCCCCCCEEEEEECCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
HYRYTGSPRAALVLDEWNAYVKRFVKVIPRNYKLMIETIQMLERSGLSYEEAAMAAFETV
HHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AKQKKAAAASPHVLQVAAK
HHHHHHCCCCCCEEEEECC
>Mature Secondary Structure
MKHYGLPEAQGLYRPEFEHDACGIGFYAHLKGKPSHDIIEKALHMLRRLEHRGGQGSDPE
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
TGDGAGIMMQIPHEYFQIVCGEMNLPEKGRYGVGMLFLPENEEKRAYYEAKFNEIIAQEG
CCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
QQLLGWRTVPVDNSKLGKLAQQSKPFIRQVFVAASDDISDELAFERKLYVIRKQFEKCVE
HHHHCEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
NNECYVASFSSRTIVYKGLLTPEQIDAFYLDLQDERFRSAFALVHSRFSTNTFPSWERAH
CCCEEEEEECCCEEEEEECCCHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCC
PNRYLIHNGEINTLRGNVNWMAAREKQFVSEAFGADLEKVTPILDTNGSDSSILDNAFEF
CCEEEEECCCEEEEECCCEEEHHHHHHHHHHHHCCCHHHCCCHHCCCCCCHHHHHHCEEE
FVLAGRNPAHVAMMLIPEPWFWDEQMDDMKKAFYEYHSCLMEPWDGPTAISFTDGKRIGA
EEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHH
ILDRNGLRPARYYVTKDDYIIFSSEVGVIEVDPNNVLYKERLSPGKMLLVDLEQGRIISD
HHCCCCCCCEEEEEECCCEEEEECCCCEEEECCCCEEECCCCCCCCEEEEECCCCCEECH
QEIKEEMASQQPYRQWIDEQMVTLDDFNVPETVEAPKSLIKLQKAFGYTFEDVEKMILPM
HHHHHHHHCCCHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AREGKDPTGAMGMDAPLAVLSERPQSLFNYFKQLFAQVTNPPIDAIREYVVTSTMTLLGK
HHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
EGNILHPDAKAARRIRLETPLLTNEQLAALKANPYPEFSCAVLPTLFTDDLKQALDELFA
CCCEECCCHHHHHEEEECCCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KADEAVENGATLLVLSDRGVDEMHVAIPVLLAVSGLHQHLIRKGTRTNVSLLVESGEARE
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHH
VHHFAALIGYGADAINPYLALETIRQASENGTIALSYREAVKTYMKAAVDGVVKVMSKMG
HHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
ISTVQSYRGAQIFEAVGIGTDVIDQYFTGTASQISGIGLDEIAKEAKLRHEAAFGARHED
HHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
NVLEAGSELQWRRNGEHHAFNPQTIHLLQWACRKNDYNLYKQYSKLANEEQLTFLRNLFD
HHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHH
FDPNRKPVPIDEVEPVKSIVRRFKTGAMSFGSISQEAHEALAIAMNRIGGKSNSGEGGED
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PARYVKDENGDWRRSAIKQVASGRFGVKSHYLVNADELQIKMAQGAKPGEGGQLPANKVY
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEECHHHEEEEEECCCCCCCCCCCCCCCCC
PWVGKVRGSTPGVELISPPPHHDIYSIEDLAQLIYDLKNANKHARISVKLVAKAGVGTIA
CCHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHH
AGVAKGNADVIVISGYDGGTGASPKTSIKHAGLPWELGLAETHQTLMLNGLRDRVILETD
HHHCCCCCCEEEEECCCCCCCCCCCCCHHCCCCCEECCHHHHHHHHHHCCCCCEEEEECC
GKLMTGRDVVMAALFGAEEFGFATAPLVVLGCVMMRVCHLDTCPVGVATQNPELRKKFMG
CCEECCHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCC
DPDHVVNFMYFVAQEVREIMAELGFRTIDEMVGRVDVLKVSERAKAHWKAKHLDLSRLLY
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCHHHHHH
QVDGPRTCGKGQNHRLETTLDYKEILPAVQPALERQEPVELKLAIHNVHRTVGAMTGGEI
HCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCHH
SKRYGEEGLPEDTIRLHFTGSAGQSFAAFAPKGMTLELVGDANDYVGKGLSGGKVIVRPP
HHHHCCCCCCCCCEEEEEECCCCCCCHHCCCCCCEEEEECCCCHHHCCCCCCCEEEEECC
HEASFAAADNVIIGNVAFYGATGGEAYIRGRAGERFAVRNSGVHAVVEGVGDHGCEYMTG
CCCCHHCCCCEEEECEEEEECCCCCEEEECCCCCEEEEECCCCHHHHHCCCCCCCCEECC
GRVVILGSVGKNFAAGMSGGIAYVLADEDSWQQTANRELVAFEWLEDEQEILEVSRMIEN
CEEEEEECCCCCHHCCCCCCEEEEEECCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
HYRYTGSPRAALVLDEWNAYVKRFVKVIPRNYKLMIETIQMLERSGLSYEEAAMAAFETV
HHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AKQKKAAAASPHVLQVAAK
HHHHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2548995; 11029411 [H]