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The map label for this gene is fabD [H]

Identifier: 138894710

GI number: 138894710

Start: 1110762

End: 1111706

Strand: Direct

Name: fabD [H]

Synonym: GTNG_1042

Alternate gene names: 138894710

Gene position: 1110762-1111706 (Clockwise)

Preceding gene: 138894709

Following gene: 138894711

Centisome position: 31.29

GC content: 56.83

Gene sequence:

>945_bases
ATGGGGAAAATCGCCTTTTTATTTCCAGGTCAAGGATCTCAAACGGTCGGCATGGCGAAAGACGCCGCTGACCATGATGC
CCGCGCCCGGGCGGTTATCGAAGCGGCCGACGAACGGCTCGGCTTTCCGCTTTCAGCGCTCATGTTTAATGGGCCGCAAG
AGGAGCTGACGCTGACATACAACGCCCAGCCGGCACTTTTGACTGCGAGCATCGCTTTGTTGGAGCTTGTCAAAGCTGCT
GGTCTTAAGGCTGATTATGTCGCCGGCCATAGTTTAGGTGAATATACGGCACTTGTCGCTGCCGGTGCGATGTCGTTTGC
CGACGCTGTCTATGCAGTGCGCCGCCGCGGCGAGCTGATGGACGAAGCAGTGCCAGCCGGTGAAGGCACGATGGCTGCCG
TGTTAGGGATGGAAGGGGAGGTGCTTGAGGCGGTGACGAATGAAATTACTGCCCAAGGCGATCCGGTCGAGCCGGCTAAC
TTCAACTGTCCAGGGCAAATCGTCATCTCCGGTTCGAAAGCGGGGGTGGAAAAAGCGGGGCAGCTGGCGAAAGAGCGCGG
TGCCAAACGCGTCATTCCGCTTGAGGTGAGCGGCCCGTTCCATTCAGCGCTGATGAAACCGGCGGCAGAACAGTTGCAAG
AAGTCCTTTCCGGCTTGGTCATCCGCGATGCTGACATTCCGGTTATCGCCAATGTGACTGCTGAACCGGTGATGAACAAA
GAAGACATCGCTCGCCTGCTCATTGAGCAGCTGTACTCGCCGGTGCGTTGGGAGCAGTCGGTACGCACGCTTTTGGCGCT
TGGTGTCGACACGTTTTTGGAAATTGGGCCTGGGAAAGTATTGTCCGGCCTCGTGAAAAAAATTGACCGCAACGCCCGCA
TTTATGCGGTAAACGATCTCGCTTCCTTAGAAGCGACCGTTGCGGCGTTGAAAGGAGAATCATGA

Upstream 100 bases:

>100_bases
TCCACGCCGTCCGCCAGGCGCGCGAAATGGTAGCGAATGATGTGATCGGCACGATCAAAGCGGAGCTTGAACGCACATCA
TAAACCAAGGAGGAACGGGA

Downstream 100 bases:

>100_bases
TGCTCGAAGGAAAAATCGCTCTCGTCACTGGAGCATCGCGCGGCATCGGGCGGGCAGTCGCTCTTGAGTTGGCCCGCCAA
GGGGCAAATGTTGCCGTCAA

Product: malonyl CoA-acyl carrier protein transacylase (FabD)

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGKIAFLFPGQGSQTVGMAKDAADHDARARAVIEAADERLGFPLSALMFNGPQEELTLTYNAQPALLTASIALLELVKAA
GLKADYVAGHSLGEYTALVAAGAMSFADAVYAVRRRGELMDEAVPAGEGTMAAVLGMEGEVLEAVTNEITAQGDPVEPAN
FNCPGQIVISGSKAGVEKAGQLAKERGAKRVIPLEVSGPFHSALMKPAAEQLQEVLSGLVIRDADIPVIANVTAEPVMNK
EDIARLLIEQLYSPVRWEQSVRTLLALGVDTFLEIGPGKVLSGLVKKIDRNARIYAVNDLASLEATVAALKGES

Sequences:

>Translated_314_residues
MGKIAFLFPGQGSQTVGMAKDAADHDARARAVIEAADERLGFPLSALMFNGPQEELTLTYNAQPALLTASIALLELVKAA
GLKADYVAGHSLGEYTALVAAGAMSFADAVYAVRRRGELMDEAVPAGEGTMAAVLGMEGEVLEAVTNEITAQGDPVEPAN
FNCPGQIVISGSKAGVEKAGQLAKERGAKRVIPLEVSGPFHSALMKPAAEQLQEVLSGLVIRDADIPVIANVTAEPVMNK
EDIARLLIEQLYSPVRWEQSVRTLLALGVDTFLEIGPGKVLSGLVKKIDRNARIYAVNDLASLEATVAALKGES
>Mature_313_residues
GKIAFLFPGQGSQTVGMAKDAADHDARARAVIEAADERLGFPLSALMFNGPQEELTLTYNAQPALLTASIALLELVKAAG
LKADYVAGHSLGEYTALVAAGAMSFADAVYAVRRRGELMDEAVPAGEGTMAAVLGMEGEVLEAVTNEITAQGDPVEPANF
NCPGQIVISGSKAGVEKAGQLAKERGAKRVIPLEVSGPFHSALMKPAAEQLQEVLSGLVIRDADIPVIANVTAEPVMNKE
DIARLLIEQLYSPVRWEQSVRTLLALGVDTFLEIGPGKVLSGLVKKIDRNARIYAVNDLASLEATVAALKGES

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=318, Percent_Identity=36.1635220125786, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=44.0366972477064, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI41872631, Length=299, Percent_Identity=29.0969899665552, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787334, Length=306, Percent_Identity=47.0588235294118, Blast_Score=242, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=31.0580204778157, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=28.9115646258503, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24665753, Length=312, Percent_Identity=35.8974358974359, Blast_Score=138, Evalue=5e-33,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33003; Mature: 32872

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKIAFLFPGQGSQTVGMAKDAADHDARARAVIEAADERLGFPLSALMFNGPQEELTLTY
CCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHEEEEE
NAQPALLTASIALLELVKAAGLKADYVAGHSLGEYTALVAAGAMSFADAVYAVRRRGELM
CCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEAVPAGEGTMAAVLGMEGEVLEAVTNEITAQGDPVEPANFNCPGQIVISGSKAGVEKAG
HHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHCHHHHH
QLAKERGAKRVIPLEVSGPFHSALMKPAAEQLQEVLSGLVIRDADIPVIANVTAEPVMNK
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCH
EDIARLLIEQLYSPVRWEQSVRTLLALGVDTFLEIGPGKVLSGLVKKIDRNARIYAVNDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCH
ASLEATVAALKGES
HHHHHHHHHHCCCC
>Mature Secondary Structure 
GKIAFLFPGQGSQTVGMAKDAADHDARARAVIEAADERLGFPLSALMFNGPQEELTLTY
CEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHEEEEE
NAQPALLTASIALLELVKAAGLKADYVAGHSLGEYTALVAAGAMSFADAVYAVRRRGELM
CCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEAVPAGEGTMAAVLGMEGEVLEAVTNEITAQGDPVEPANFNCPGQIVISGSKAGVEKAG
HHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHCHHHHH
QLAKERGAKRVIPLEVSGPFHSALMKPAAEQLQEVLSGLVIRDADIPVIANVTAEPVMNK
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCH
EDIARLLIEQLYSPVRWEQSVRTLLALGVDTFLEIGPGKVLSGLVKKIDRNARIYAVNDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCH
ASLEATVAALKGES
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]