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The map label for this gene is mraY [H]

Identifier: 138894652

GI number: 138894652

Start: 1048993

End: 1049967

Strand: Direct

Name: mraY [H]

Synonym: GTNG_0982

Alternate gene names: 138894652

Gene position: 1048993-1049967 (Clockwise)

Preceding gene: 138894651

Following gene: 138894653

Centisome position: 29.55

GC content: 50.46

Gene sequence:

>975_bases
ATGCCAGAGCAAATAATCGTCATTGCGATGGCGGTCTCCTTTTTAATCACAGTCATTTTGTCCCCGCTATTTATCCCGTT
TTTGCGACGGTTAAAATTTGGGCAAAGTATTCGCGAGGAAGGACCGAAGTCGCACCAAAAAAAATCGGGCACTCCGACAA
TGGGCGGCATAATGATTTTGCTTTCCATCATTGCGACGACCGTATGGGTGACGGCCAAGTTTTCCGTTCTTTCGGCGGGG
ACATATTTATTGTTGTTTGTAACGATCGGTTATGGGGTGCTCGGCTTTTTAGACGACATGATTAAAGTTGTGATGAAGCG
AAATCTTGGACTGACAAGCCGGCAAAAATTTATCGGCCAGCTCATCATTGCGGTCATTTTCTTTTTTGTCTATCGGCAAA
GCGGTTTTTCGACAGCGCTACATATTCCCGGCACTGACTGGTCGTTTGACCTTGGTTGGGCATACGGGGTGTTGCTGTTG
TTCATGCTCGTTGGCGGTTCGAACGCTGTCAATTTGACCGATGGGCTTGACGGGCTGCTCGCCGGAACGGCGGCCATCGC
CTTTGGCGCTTACGCCGTCTTGGCTTGGAATCAAGGCCAGTACGACGTGGCTGTGTTTTGTGTGGCTGTTGTCGGCGCCG
TGCTCGGCTTTTTAGTGTTTAACGCTCATCCGGCGAAAGTGTTTATGGGCGATACCGGTTCGCTTGCGCTCGGCGGAGCG
ATTGCCGCCGTCGCTGTCTTAACGAAGCTTGAGCTGCTGCTTGTTGTGATCGGCGGCGTGTTTGTCATTGAGACGCTGTC
GGTCATTATTCAAGTTGCCTCATTCAAAATGACCGGTAAGCGCGTCTTTCGTATGAGTCCGCTCCATCATCATTATGAGC
TCGTCGGCTGGTCGGAATGGCGCATTGTCGTCACGTTTTGGGCTGTCGGCCTTTTATTCGCAATGCTAGGAATTTATATC
GAGGTGTGGATTTAA

Upstream 100 bases:

>100_bases
GCGGAACATACGCTCCAGCTGATACTGAAGCTCGCCTGCAGCTCGCTGAATTGCAGAGAAGGTGGCTGAGCGTGCGGCCG
GCAAAAGGATGTGACGATTC

Downstream 100 bases:

>100_bases
TTGAAACCGACTCCTTTTTATCAACATCGTCGTGTGCTTGTCATTGGATTGGCTAAAAGTGGGGCGGCGGCGGCTCGGTT
GCTTGCTGAATTAGGTGTTG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MPEQIIVIAMAVSFLITVILSPLFIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGIMILLSIIATTVWVTAKFSVLSAG
TYLLLFVTIGYGVLGFLDDMIKVVMKRNLGLTSRQKFIGQLIIAVIFFFVYRQSGFSTALHIPGTDWSFDLGWAYGVLLL
FMLVGGSNAVNLTDGLDGLLAGTAAIAFGAYAVLAWNQGQYDVAVFCVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
IAAVAVLTKLELLLVVIGGVFVIETLSVIIQVASFKMTGKRVFRMSPLHHHYELVGWSEWRIVVTFWAVGLLFAMLGIYI
EVWI

Sequences:

>Translated_324_residues
MPEQIIVIAMAVSFLITVILSPLFIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGIMILLSIIATTVWVTAKFSVLSAG
TYLLLFVTIGYGVLGFLDDMIKVVMKRNLGLTSRQKFIGQLIIAVIFFFVYRQSGFSTALHIPGTDWSFDLGWAYGVLLL
FMLVGGSNAVNLTDGLDGLLAGTAAIAFGAYAVLAWNQGQYDVAVFCVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
IAAVAVLTKLELLLVVIGGVFVIETLSVIIQVASFKMTGKRVFRMSPLHHHYELVGWSEWRIVVTFWAVGLLFAMLGIYI
EVWI
>Mature_323_residues
PEQIIVIAMAVSFLITVILSPLFIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGIMILLSIIATTVWVTAKFSVLSAGT
YLLLFVTIGYGVLGFLDDMIKVVMKRNLGLTSRQKFIGQLIIAVIFFFVYRQSGFSTALHIPGTDWSFDLGWAYGVLLLF
MLVGGSNAVNLTDGLDGLLAGTAAIAFGAYAVLAWNQGQYDVAVFCVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGAI
AAVAVLTKLELLLVVIGGVFVIETLSVIIQVASFKMTGKRVFRMSPLHHHYELVGWSEWRIVVTFWAVGLLFAMLGIYIE
VWI

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=332, Percent_Identity=44.8795180722892, Blast_Score=247, Evalue=6e-67,
Organism=Escherichia coli, GI1790218, Length=204, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 35190; Mature: 35058

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEQIIVIAMAVSFLITVILSPLFIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGIMIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHCCCCCCCHHHHHHH
LSIIATTVWVTAKFSVLSAGTYLLLFVTIGYGVLGFLDDMIKVVMKRNLGLTSRQKFIGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LIIAVIFFFVYRQSGFSTALHIPGTDWSFDLGWAYGVLLLFMLVGGSNAVNLTDGLDGLL
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
AGTAAIAFGAYAVLAWNQGQYDVAVFCVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
HHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
IAAVAVLTKLELLLVVIGGVFVIETLSVIIQVASFKMTGKRVFRMSPLHHHYELVGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCHHHHHEECCCHH
RIVVTFWAVGLLFAMLGIYIEVWI
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PEQIIVIAMAVSFLITVILSPLFIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGIMIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHCCCCCCCHHHHHHH
LSIIATTVWVTAKFSVLSAGTYLLLFVTIGYGVLGFLDDMIKVVMKRNLGLTSRQKFIGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LIIAVIFFFVYRQSGFSTALHIPGTDWSFDLGWAYGVLLLFMLVGGSNAVNLTDGLDGLL
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
AGTAAIAFGAYAVLAWNQGQYDVAVFCVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
HHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
IAAVAVLTKLELLLVVIGGVFVIETLSVIIQVASFKMTGKRVFRMSPLHHHYELVGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCHHHHHEECCCHH
RIVVTFWAVGLLFAMLGIYIEVWI
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA