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The map label for this gene is ctaD [H]

Identifier: 138894618

GI number: 138894618

Start: 1019959

End: 1021827

Strand: Direct

Name: ctaD [H]

Synonym: GTNG_0948

Alternate gene names: 138894618

Gene position: 1019959-1021827 (Clockwise)

Preceding gene: 138894617

Following gene: 138894619

Centisome position: 28.73

GC content: 49.76

Gene sequence:

>1869_bases
GTGAGTACGATCGCTCGCAAAAAGGGCGTTGGGGCCGTTTTATGGGATTACCTGACGACGGTCGATCATAAAAAGATCGC
CCATCTGTATTTGATCTCTGGTGGCATTTTCTTCCTGCTTGGCGGTCTTGAGGCGTTGTTTATCCGCATTCAGCTTGCGA
AGCCGAACAACGATTTTCTTGTTGGCGGCTTGTACAACGAAGTGCTGACGATGCACGGGACGACGATGATTTTCTTGGCT
GCCATGCCGCTTGTTTTCGCGTTTATGAATGCGGTCGTGCCGCTGCAAATCGGCGCACGCGATGTTGCATTTCCGTTTTT
AAACGCGCTTGGTTTTTGGCTCTTTTTCTTCGGTGGGGTGTTTTTAAACTGTTCATGGTTTTTAGGCGGCGCTCCTGACG
CAGGTTGGACATCGTATGCGTCGTTGGCGCTCGATTCGAAAGCGCACCATGGTGTTGACTTTTACACCCTTGGGTTGCAA
ATTTCAGGCTTGGGGACATTAATAGGCGGAATTAACTTTCTTGTTACGATTATTAACATGCGCGCTCCGGGCATGACGTT
TATGCGTATGCCGATGTTCACTTGGGCGACATTTGTGACGTCTGCGCTCATCTTGTTCGCGTTTCCGCCGTTGACGGTTG
GATTGATTTTCTTGATGATGGACCGATTGTTTGGTGGAAACTTTTTCAATCCGGCTGCTGGCGGTAATACGATTATTTGG
GAGCATTTGTTCTGGGTGTTCGGCCATCCGGAAGTATACATTCTTGTATTGCCAGCATTCGGTATTTTCTCGGAAATTTT
CGCGACATTCTCTCGTAAACGGCTGTTTGGCTATTCATCAATGGTATTTGCAACGGTGCTCATCGCCTTCTTAGGATTCA
TGGTGTGGGCGCACCATATGTTTACGGTCGGAATGGGGCCGATTGCGAACGCCATCTTTTCTGTCGCAACGATGACAATT
GCGGTGCCGACAGGAATTAAAATTTTCAACTGGCTATTTACAATGTGGGGCGGGAGCATCAAGTTTACGACGCCGATGCA
TTATGCGGTGGCCTTCATCCCATCGTTCGTTATGGGTGGGGTAACCGGCGTTATGCTGGCAGCGGCAGCGGCTGACTATC
AGTATCATGACAGCTATTTCGTTGTTGCCCACTTCCATTACGTCATTGTCGGTGGGGTTGTGTTTGCCTTACTTGCTGGT
ACGCATTACTGGTGGCCGAAAATGTTTGGCCGCATGCTAAACGAGACACTTGGCAAAATTACGTTCTGGCTGTTCTTTAT
CGGATTCCATTTAACGTTCTTTATCCAGCATTTCCTTGGCTTAATGGGAATGCCGCGTCGCGTGTTCACATTCTTGCCGG
GGCAAGGGTTGGAGACCGGTAACTTCATCAGTACGGTCGGAGCGTTCTTTATGGCGGCCGCAACGGTTGTTTTACTCATT
AACATCGTGATTTCGGTAAAAGGTGAAAAAGCGCCGGCCGATGCATGGGGTGACGGCCGCACGCTCGAATGGGCGATCGC
TTCGCCGCCACCAGTATACAACTTTGCCCAATTGCCGCTTGTTCGCGGGTTAGATCCTCTCTGGCTTGAAAAAATGGAAG
GGAAGAAGGAATTGACGCCAGCTGAGCCACTTGGCGACATTCATATGCCGAACTCGTCATTCCTGCCGTTTATCATGTCG
TTCGGCTTGTTTGTGGCGGCATTTGGCTTTACGTACCATCAAGAGACGGCTTGGGGCTTGCCGGTGGGTATTCTCGGCTT
GCTCATTACGTTCGGTTCGATGTTCTTGCGCTCAGTGATTGATGATCACGGTTTCCACATTCATAAAGAAGAAGTGCTTG
AACTTGAGAAGAAGGGGGCGAACGCCTGA

Upstream 100 bases:

>100_bases
ACGGGTACATATGGCCAGCTGACAGAAGAACAGCTTGATGCATTGACAAAATATTTAATGAGCTTAAAAGTGGAATAAGG
CATAAAAGGGAGGTTTCGCT

Downstream 100 bases:

>100_bases
TGCACGTAGAGGAAAAACTGACGCCCGAGACGTTCCCGGCGGCGCCGGAACGAGCCACTCTTGAGGGGAAAAATAAATTT
CTTGGTTTCTGGCTGTTTTT

Product: cytochrome caa3-type oxidase I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MSTIARKKGVGAVLWDYLTTVDHKKIAHLYLISGGIFFLLGGLEALFIRIQLAKPNNDFLVGGLYNEVLTMHGTTMIFLA
AMPLVFAFMNAVVPLQIGARDVAFPFLNALGFWLFFFGGVFLNCSWFLGGAPDAGWTSYASLALDSKAHHGVDFYTLGLQ
ISGLGTLIGGINFLVTIINMRAPGMTFMRMPMFTWATFVTSALILFAFPPLTVGLIFLMMDRLFGGNFFNPAAGGNTIIW
EHLFWVFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSSMVFATVLIAFLGFMVWAHHMFTVGMGPIANAIFSVATMTI
AVPTGIKIFNWLFTMWGGSIKFTTPMHYAVAFIPSFVMGGVTGVMLAAAAADYQYHDSYFVVAHFHYVIVGGVVFALLAG
THYWWPKMFGRMLNETLGKITFWLFFIGFHLTFFIQHFLGLMGMPRRVFTFLPGQGLETGNFISTVGAFFMAAATVVLLI
NIVISVKGEKAPADAWGDGRTLEWAIASPPPVYNFAQLPLVRGLDPLWLEKMEGKKELTPAEPLGDIHMPNSSFLPFIMS
FGLFVAAFGFTYHQETAWGLPVGILGLLITFGSMFLRSVIDDHGFHIHKEEVLELEKKGANA

Sequences:

>Translated_622_residues
MSTIARKKGVGAVLWDYLTTVDHKKIAHLYLISGGIFFLLGGLEALFIRIQLAKPNNDFLVGGLYNEVLTMHGTTMIFLA
AMPLVFAFMNAVVPLQIGARDVAFPFLNALGFWLFFFGGVFLNCSWFLGGAPDAGWTSYASLALDSKAHHGVDFYTLGLQ
ISGLGTLIGGINFLVTIINMRAPGMTFMRMPMFTWATFVTSALILFAFPPLTVGLIFLMMDRLFGGNFFNPAAGGNTIIW
EHLFWVFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSSMVFATVLIAFLGFMVWAHHMFTVGMGPIANAIFSVATMTI
AVPTGIKIFNWLFTMWGGSIKFTTPMHYAVAFIPSFVMGGVTGVMLAAAAADYQYHDSYFVVAHFHYVIVGGVVFALLAG
THYWWPKMFGRMLNETLGKITFWLFFIGFHLTFFIQHFLGLMGMPRRVFTFLPGQGLETGNFISTVGAFFMAAATVVLLI
NIVISVKGEKAPADAWGDGRTLEWAIASPPPVYNFAQLPLVRGLDPLWLEKMEGKKELTPAEPLGDIHMPNSSFLPFIMS
FGLFVAAFGFTYHQETAWGLPVGILGLLITFGSMFLRSVIDDHGFHIHKEEVLELEKKGANA
>Mature_621_residues
STIARKKGVGAVLWDYLTTVDHKKIAHLYLISGGIFFLLGGLEALFIRIQLAKPNNDFLVGGLYNEVLTMHGTTMIFLAA
MPLVFAFMNAVVPLQIGARDVAFPFLNALGFWLFFFGGVFLNCSWFLGGAPDAGWTSYASLALDSKAHHGVDFYTLGLQI
SGLGTLIGGINFLVTIINMRAPGMTFMRMPMFTWATFVTSALILFAFPPLTVGLIFLMMDRLFGGNFFNPAAGGNTIIWE
HLFWVFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSSMVFATVLIAFLGFMVWAHHMFTVGMGPIANAIFSVATMTIA
VPTGIKIFNWLFTMWGGSIKFTTPMHYAVAFIPSFVMGGVTGVMLAAAAADYQYHDSYFVVAHFHYVIVGGVVFALLAGT
HYWWPKMFGRMLNETLGKITFWLFFIGFHLTFFIQHFLGLMGMPRRVFTFLPGQGLETGNFISTVGAFFMAAATVVLLIN
IVISVKGEKAPADAWGDGRTLEWAIASPPPVYNFAQLPLVRGLDPLWLEKMEGKKELTPAEPLGDIHMPNSSFLPFIMSF
GLFVAAFGFTYHQETAWGLPVGILGLLITFGSMFLRSVIDDHGFHIHKEEVLELEKKGANA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=505, Percent_Identity=42.3762376237624, Blast_Score=367, Evalue=1e-101,
Organism=Escherichia coli, GI1786634, Length=613, Percent_Identity=45.6769983686786, Blast_Score=503, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6226519, Length=527, Percent_Identity=41.9354838709677, Blast_Score=381, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6226524, Length=321, Percent_Identity=43.613707165109, Blast_Score=249, Evalue=9e-67,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=36.144578313253, Blast_Score=140, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 68769; Mature: 68638

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB ; PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIARKKGVGAVLWDYLTTVDHKKIAHLYLISGGIFFLLGGLEALFIRIQLAKPNNDFL
CCCCHHHCCCHHHHHHHHHHCCHHHHHHHEEECCHHHHHHHHHHEEEEEEEEECCCCCEE
VGGLYNEVLTMHGTTMIFLAAMPLVFAFMNAVVPLQIGARDVAFPFLNALGFWLFFFGGV
ECHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
FLNCSWFLGGAPDAGWTSYASLALDSKAHHGVDFYTLGLQISGLGTLIGGINFLVTIINM
HHEEEEEECCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHC
RAPGMTFMRMPMFTWATFVTSALILFAFPPLTVGLIFLMMDRLFGGNFFNPAAGGNTIIW
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EHLFWVFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSSMVFATVLIAFLGFMVWAHHM
HHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
FTVGMGPIANAIFSVATMTIAVPTGIKIFNWLFTMWGGSIKFTTPMHYAVAFIPSFVMGG
HHHCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHH
VTGVMLAAAAADYQYHDSYFVVAHFHYVIVGGVVFALLAGTHYWWPKMFGRMLNETLGKI
HHHHHHHHHHHCCEECCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TFWLFFIGFHLTFFIQHFLGLMGMPRRVFTFLPGQGLETGNFISTVGAFFMAAATVVLLI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NIVISVKGEKAPADAWGDGRTLEWAIASPPPVYNFAQLPLVRGLDPLWLEKMEGKKELTP
HHHHEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHCHHHHCCCHHHHHHHCCCCCCCC
AEPLGDIHMPNSSFLPFIMSFGLFVAAFGFTYHQETAWGLPVGILGLLITFGSMFLRSVI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHHH
DDHGFHIHKEEVLELEKKGANA
HCCCCEECHHHHHHHHHCCCCC
>Mature Secondary Structure 
STIARKKGVGAVLWDYLTTVDHKKIAHLYLISGGIFFLLGGLEALFIRIQLAKPNNDFL
CCCHHHCCCHHHHHHHHHHCCHHHHHHHEEECCHHHHHHHHHHEEEEEEEEECCCCCEE
VGGLYNEVLTMHGTTMIFLAAMPLVFAFMNAVVPLQIGARDVAFPFLNALGFWLFFFGGV
ECHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
FLNCSWFLGGAPDAGWTSYASLALDSKAHHGVDFYTLGLQISGLGTLIGGINFLVTIINM
HHEEEEEECCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHC
RAPGMTFMRMPMFTWATFVTSALILFAFPPLTVGLIFLMMDRLFGGNFFNPAAGGNTIIW
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EHLFWVFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSSMVFATVLIAFLGFMVWAHHM
HHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
FTVGMGPIANAIFSVATMTIAVPTGIKIFNWLFTMWGGSIKFTTPMHYAVAFIPSFVMGG
HHHCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHH
VTGVMLAAAAADYQYHDSYFVVAHFHYVIVGGVVFALLAGTHYWWPKMFGRMLNETLGKI
HHHHHHHHHHHCCEECCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TFWLFFIGFHLTFFIQHFLGLMGMPRRVFTFLPGQGLETGNFISTVGAFFMAAATVVLLI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NIVISVKGEKAPADAWGDGRTLEWAIASPPPVYNFAQLPLVRGLDPLWLEKMEGKKELTP
HHHHEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHCHHHHCCCHHHHHHHCCCCCCCC
AEPLGDIHMPNSSFLPFIMSFGLFVAAFGFTYHQETAWGLPVGILGLLITFGSMFLRSVI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHHH
DDHGFHIHKEEVLELEKKGANA
HCCCCEECHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1964459; 2844737; 1652469 [H]