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The map label for this gene is qor [H]

Identifier: 138894566

GI number: 138894566

Start: 972141

End: 973115

Strand: Direct

Name: qor [H]

Synonym: GTNG_0896

Alternate gene names: 138894566

Gene position: 972141-973115 (Clockwise)

Preceding gene: 138894565

Following gene: 138894569

Centisome position: 27.38

GC content: 58.26

Gene sequence:

>975_bases
ATGAAAATGGTACAATTTACGGAATACGGCGGTCCAGATGTGCTTGAGGTGAAAGAGGTAGAACGCCCGTCGCCATCCGG
TCGCCACGTGTTGATTGAGGCGGAGGCGATTGGCGTCAATTACGCCGATACAGCGAGACGAGAAGGACGCTACGTTGTAC
CGACACCGCTTCCATTCGTGCCTGGAACTGAAGTGGCCGGTGTCGTCCGTGAAGTTGGTCCGGACGTGCAGGCGATCCGC
CCAGGGCAGCGCGTCGTCGCCTTAGTGGAGTCGGGAGGGTACGCCGAGTTTGTTGCCGTTGATGAGCGGGCGGTCGTGCC
GCTGCCGGATGGGATGGATGTCCAACAAGCAGCGGCGCTGCCGGTGCAAGGGTTAAGTGCCTATCATATTTTAAAAACGA
TGAGCCGTCTGGAGGACGGAGAAACGGTGCTCGTTCACGCGGCAGCCGGCGGCGTCGGCACGCTCGCCGTGCAGCTGGCG
AAACGGTTCGGCGCGAAAACCGTTATCGCCACGGCGAGCACCGAAGAAAAGCGGGAGCTTGCTCGGCGTCTTGGTGCTGA
TGTGACGATCGATTATACGCAAAACGACTGGACCAAGGCTGTGATGGAGGCGACTGATGGCCGCGGCGTTGACGTTGCCT
TGGAAATGGTGGGCGGCGGTATTTTCCATCAAACGCTTGATTGCCTCGCCCCGTTCGGTCGCCTTGTTGTTTACGGCATG
GCAAGCGGGGAGATGACGCGCCTTAACCCAGCTCGTCTGATGGCGAAAAACTGGTCTGTCGTCGGCTTTTTCTTGCCGCA
AATCATGCGGAAGCGGGCGCTGTACGAGCAAAGCTTGCGTGAATTGCTCCATTGGGTGCAAGAAGGAAGCTTAGAGCTGA
TCATCGGCGGCGTCTATCCGCTTGAGCAGGCGGCTATGGTACACGAGCTGTTGCAAGGGAGAAAAACGAGCGGCAAACTG
TTACTTGTGCCGTAA

Upstream 100 bases:

>100_bases
ATGGAGCTCTTTCTGTCGTTCCGAAACTTGAGTGTGAGTCGTTTGGACCGGAAATGCGTGATATGACGCAAACGAAAGTA
GCGGGGGAGGGGAAACAACA

Downstream 100 bases:

>100_bases
AAAGAGGAATGGAGTTGACCAGAAAGGTCGCCTTTCTTCAAGAGAGACAAGATGCTGTATTGTGGAAGTGTTCAGATCGT
ATATCGTGATGAAAAAGGGT

Product: NADPH quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKMVQFTEYGGPDVLEVKEVERPSPSGRHVLIEAEAIGVNYADTARREGRYVVPTPLPFVPGTEVAGVVREVGPDVQAIR
PGQRVVALVESGGYAEFVAVDERAVVPLPDGMDVQQAAALPVQGLSAYHILKTMSRLEDGETVLVHAAAGGVGTLAVQLA
KRFGAKTVIATASTEEKRELARRLGADVTIDYTQNDWTKAVMEATDGRGVDVALEMVGGGIFHQTLDCLAPFGRLVVYGM
ASGEMTRLNPARLMAKNWSVVGFFLPQIMRKRALYEQSLRELLHWVQEGSLELIIGGVYPLEQAAMVHELLQGRKTSGKL
LLVP

Sequences:

>Translated_324_residues
MKMVQFTEYGGPDVLEVKEVERPSPSGRHVLIEAEAIGVNYADTARREGRYVVPTPLPFVPGTEVAGVVREVGPDVQAIR
PGQRVVALVESGGYAEFVAVDERAVVPLPDGMDVQQAAALPVQGLSAYHILKTMSRLEDGETVLVHAAAGGVGTLAVQLA
KRFGAKTVIATASTEEKRELARRLGADVTIDYTQNDWTKAVMEATDGRGVDVALEMVGGGIFHQTLDCLAPFGRLVVYGM
ASGEMTRLNPARLMAKNWSVVGFFLPQIMRKRALYEQSLRELLHWVQEGSLELIIGGVYPLEQAAMVHELLQGRKTSGKL
LLVP
>Mature_324_residues
MKMVQFTEYGGPDVLEVKEVERPSPSGRHVLIEAEAIGVNYADTARREGRYVVPTPLPFVPGTEVAGVVREVGPDVQAIR
PGQRVVALVESGGYAEFVAVDERAVVPLPDGMDVQQAAALPVQGLSAYHILKTMSRLEDGETVLVHAAAGGVGTLAVQLA
KRFGAKTVIATASTEEKRELARRLGADVTIDYTQNDWTKAVMEATDGRGVDVALEMVGGGIFHQTLDCLAPFGRLVVYGM
ASGEMTRLNPARLMAKNWSVVGFFLPQIMRKRALYEQSLRELLHWVQEGSLELIIGGVYPLEQAAMVHELLQGRKTSGKL
LLVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=333, Percent_Identity=33.9339339339339, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI22538444, Length=333, Percent_Identity=33.9339339339339, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=33.7423312883436, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=33.7423312883436, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI194239676, Length=326, Percent_Identity=30.9815950920245, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI18379349, Length=342, Percent_Identity=32.4561403508772, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI24308257, Length=343, Percent_Identity=28.2798833819242, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI28557745, Length=295, Percent_Identity=34.2372881355932, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=31.1224489795918, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI47519420, Length=143, Percent_Identity=37.7622377622378, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI67078404, Length=306, Percent_Identity=26.4705882352941, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI67078406, Length=272, Percent_Identity=26.4705882352941, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI90669511, Length=164, Percent_Identity=34.1463414634146, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI41872631, Length=161, Percent_Identity=29.1925465838509, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI226059159, Length=321, Percent_Identity=27.4143302180685, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226059133, Length=321, Percent_Identity=27.4143302180685, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226056130, Length=247, Percent_Identity=28.7449392712551, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=330, Percent_Identity=35.4545454545455, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI87081918, Length=289, Percent_Identity=27.681660899654, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI226510941, Length=216, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790045, Length=237, Percent_Identity=25.7383966244726, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=323, Percent_Identity=30.3405572755418, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17536829, Length=291, Percent_Identity=29.2096219931272, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71987554, Length=224, Percent_Identity=29.9107142857143, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=191, Percent_Identity=27.2251308900524, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17556000, Length=266, Percent_Identity=25.9398496240602, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI212642053, Length=253, Percent_Identity=25.296442687747, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=325, Percent_Identity=32.3076923076923, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324486, Length=293, Percent_Identity=28.6689419795222, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=295, Percent_Identity=28.135593220339, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=350, Percent_Identity=24.8571428571429, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=290, Percent_Identity=24.4827586206897, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI45550423, Length=298, Percent_Identity=25.8389261744966, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221330659, Length=240, Percent_Identity=27.0833333333333, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920632, Length=240, Percent_Identity=27.0833333333333, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24581345, Length=194, Percent_Identity=27.8350515463918, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35099; Mature: 35099

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMVQFTEYGGPDVLEVKEVERPSPSGRHVLIEAEAIGVNYADTARREGRYVVPTPLPFV
CCCEEEECCCCCCEEEEHHCCCCCCCCCEEEEEEEEECCCCHHHHHHCCCEECCCCCCCC
PGTEVAGVVREVGPDVQAIRPGQRVVALVESGGYAEFVAVDERAVVPLPDGMDVQQAAAL
CCCHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCEEEEEECCEEEEECCCCCCHHHHHCC
PVQGLSAYHILKTMSRLEDGETVLVHAAAGGVGTLAVQLAKRFGAKTVIATASTEEKREL
CCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHH
ARRLGADVTIDYTQNDWTKAVMEATDGRGVDVALEMVGGGIFHQTLDCLAPFGRLVVYGM
HHHCCCCEEEEECCCHHHHHHHHCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHEEEEEC
ASGEMTRLNPARLMAKNWSVVGFFLPQIMRKRALYEQSLRELLHWVQEGSLELIIGGVYP
CCCCEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LEQAAMVHELLQGRKTSGKLLLVP
HHHHHHHHHHHCCCCCCCCEEEEC
>Mature Secondary Structure
MKMVQFTEYGGPDVLEVKEVERPSPSGRHVLIEAEAIGVNYADTARREGRYVVPTPLPFV
CCCEEEECCCCCCEEEEHHCCCCCCCCCEEEEEEEEECCCCHHHHHHCCCEECCCCCCCC
PGTEVAGVVREVGPDVQAIRPGQRVVALVESGGYAEFVAVDERAVVPLPDGMDVQQAAAL
CCCHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCEEEEEECCEEEEECCCCCCHHHHHCC
PVQGLSAYHILKTMSRLEDGETVLVHAAAGGVGTLAVQLAKRFGAKTVIATASTEEKREL
CCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHH
ARRLGADVTIDYTQNDWTKAVMEATDGRGVDVALEMVGGGIFHQTLDCLAPFGRLVVYGM
HHHCCCCEEEEECCCHHHHHHHHCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHEEEEEC
ASGEMTRLNPARLMAKNWSVVGFFLPQIMRKRALYEQSLRELLHWVQEGSLELIIGGVYP
CCCCEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LEQAAMVHELLQGRKTSGKLLLVP
HHHHHHHHHHHCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]