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The map label for this gene is fabL [H]

Identifier: 138894386

GI number: 138894386

Start: 792155

End: 792931

Strand: Direct

Name: fabL [H]

Synonym: GTNG_0714

Alternate gene names: 138894386

Gene position: 792155-792931 (Clockwise)

Preceding gene: 138894383

Following gene: 138894387

Centisome position: 22.31

GC content: 52.25

Gene sequence:

>777_bases
ATGACATTATCATTGGAAGGACGTACATATGTCGTCATGGGGGTGGCGAACAAGCGGAGCATCGCCTGGGGAATCGCCCG
TTCGCTCCACGCTGCCGGTGCCCGACTCGTATTTACATACGCCGGAGAGCGGTTTGAAAAGGAAGTACGGGCGCTTGTCG
ATACGTTGGAAGATGAACGTTCGCTTCTGTTGCCGTGCGATGTGGCAAATGACGAGGACATCGTTCAATGTTTTGCGCAA
ATTAAAGAACAAGTCGGCGTTATTCATGGTGTCGCCCACTGCATCGCCTATGCCAATAAGGATGATTTAAGCGGCGAGTA
CATGAAGGTGAGCCGCGACGGCTTTTTGCTTGCTCATAATATTAGCGCCTATTCCCTCACTGCGGTGGCACGCGAGGCGA
AAGAGCTCATGACCGAAGGCGGCAGCATCGTCACTCTCACGTACTTAGGCGGTGAGCGCGTTGTGCAAAACTACAATATC
ATGGGAGTGGCGAAAGCGTCGTTGGATGCGAGTGTCAAATACTTGGCAAACGATCTAGGCAAATACGGCATCCGCGTCAA
CGCCATTTCCGCAGGCCCTATTCGCACGCTGTCGGCCAAAGGAGTGAGCGATTTCAACTCGATTTTAAAAGAGATCGAGG
AGCGCGCACCGCTCCGTCGGACGACGACGCAAGAGGAAGTCGGTGATGCAGCACTGTTTTTGTTCAGCGATTTATCGCGT
GGCATCACCGGGGAAATCATTCATGTCGACTCTGGATACCATATTTTAGGATACTAA

Upstream 100 bases:

>100_bases
AAGCAAAAGAGCGGCAGCTCATTTACATTGTCCGCGGCATATCCTATAATAGAATTAACACCTGGTGCTAATATTAAATA
ATAATTAGGAGGATGAACGA

Downstream 100 bases:

>100_bases
AAAAACGAGGCAGCCGCCCTAGTACGTGGGGCGGCTGTTTTTTGTCCGTCTGAGGGCAATTATCGGAATGGAAGGCATAC
ATATATAAAGGTAAGGCAAG

Product: enoyl-(acyl carrier protein) reductase

Products: NA

Alternate protein names: Cold shock-induced protein 15; CSI15; NADH-dependent enoyl-ACP reductase; Vegetative protein 241; VEG241 [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTLSLEGRTYVVMGVANKRSIAWGIARSLHAAGARLVFTYAGERFEKEVRALVDTLEDERSLLLPCDVANDEDIVQCFAQ
IKEQVGVIHGVAHCIAYANKDDLSGEYMKVSRDGFLLAHNISAYSLTAVAREAKELMTEGGSIVTLTYLGGERVVQNYNI
MGVAKASLDASVKYLANDLGKYGIRVNAISAGPIRTLSAKGVSDFNSILKEIEERAPLRRTTTQEEVGDAALFLFSDLSR
GITGEIIHVDSGYHILGY

Sequences:

>Translated_258_residues
MTLSLEGRTYVVMGVANKRSIAWGIARSLHAAGARLVFTYAGERFEKEVRALVDTLEDERSLLLPCDVANDEDIVQCFAQ
IKEQVGVIHGVAHCIAYANKDDLSGEYMKVSRDGFLLAHNISAYSLTAVAREAKELMTEGGSIVTLTYLGGERVVQNYNI
MGVAKASLDASVKYLANDLGKYGIRVNAISAGPIRTLSAKGVSDFNSILKEIEERAPLRRTTTQEEVGDAALFLFSDLSR
GITGEIIHVDSGYHILGY
>Mature_257_residues
TLSLEGRTYVVMGVANKRSIAWGIARSLHAAGARLVFTYAGERFEKEVRALVDTLEDERSLLLPCDVANDEDIVQCFAQI
KEQVGVIHGVAHCIAYANKDDLSGEYMKVSRDGFLLAHNISAYSLTAVAREAKELMTEGGSIVTLTYLGGERVVQNYNIM
GVAKASLDASVKYLANDLGKYGIRVNAISAGPIRTLSAKGVSDFNSILKEIEERAPLRRTTTQEEVGDAALFLFSDLSRG
ITGEIIHVDSGYHILGY

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=27.1317829457364, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787545, Length=252, Percent_Identity=47.2222222222222, Blast_Score=243, Evalue=6e-66,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=27.7992277992278, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=235, Percent_Identity=29.7872340425532, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 28094; Mature: 27963

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSLEGRTYVVMGVANKRSIAWGIARSLHAAGARLVFTYAGERFEKEVRALVDTLEDER
CEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCC
SLLLPCDVANDEDIVQCFAQIKEQVGVIHGVAHCIAYANKDDLSGEYMKVSRDGFLLAHN
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEC
ISAYSLTAVAREAKELMTEGGSIVTLTYLGGERVVQNYNIMGVAKASLDASVKYLANDLG
CCHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCEEEEEECHHHHHHHHHHHHHH
KYGIRVNAISAGPIRTLSAKGVSDFNSILKEIEERAPLRRTTTQEEVGDAALFLFSDLSR
HCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
GITGEIIHVDSGYHILGY
CCCEEEEEECCCCEEECC
>Mature Secondary Structure 
TLSLEGRTYVVMGVANKRSIAWGIARSLHAAGARLVFTYAGERFEKEVRALVDTLEDER
EEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCC
SLLLPCDVANDEDIVQCFAQIKEQVGVIHGVAHCIAYANKDDLSGEYMKVSRDGFLLAHN
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEC
ISAYSLTAVAREAKELMTEGGSIVTLTYLGGERVVQNYNIMGVAKASLDASVKYLANDLG
CCHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCEEEEEECHHHHHHHHHHHHHH
KYGIRVNAISAGPIRTLSAKGVSDFNSILKEIEERAPLRRTTTQEEVGDAALFLFSDLSR
HCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
GITGEIIHVDSGYHILGY
CCCEEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 8755892; 9298659 [H]