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The map label for this gene is ppnK [H]

Identifier: 138894382

GI number: 138894382

Start: 788083

End: 788898

Strand: Direct

Name: ppnK [H]

Synonym: GTNG_0710

Alternate gene names: 138894382

Gene position: 788083-788898 (Clockwise)

Preceding gene: 138894381

Following gene: 138894383

Centisome position: 22.2

GC content: 52.82

Gene sequence:

>816_bases
ATGAAACGAATGGACGCACCGCTGGCGTTTGCCATTACTTCAAAAGGGGATGATACTTCGAACGCCCTCGCGCAGAAGAT
GAAAACGTATTTGCTTGATTTCGACTTGCGTTACGATGAAGAGGCCCCTGACTTAATCATTTCCGTAGGTGGGGATGGAA
CGCTTTTATACGCGTTCCATCGCTATTGCCACCGGTTAGACAAGACGGCGTTCGTCGGCATCCATACCGGTCATCTCGGT
TTTTATGCTGACTGGGTGCCGGAAGAAATTGAAAAGCTCGTCATCGCTATCGCCAAAACGCCGTACCAGGTCGTTGAGTA
TCCGTTGCTTGAGGTGACGATCCGCTATCTTAACGGCGGGAGCGAGGCGAAGTATTTGGCGCTCAATGAATGTACGGTGA
AATGTGTCAGCGGCACGCTCGTCATGGACGTTGAGATCCGCGGCGACTTGTTTGAACGGTTTCGCGGTGACGGGCTGTGC
ATTTCGACGCCGACCGGCAGCACGGCATATAATAAAGCGCTCGGCGGGGCGATTTTGCATCCATCGCTTGAAGCGATTCA
AGTGACGGAGATGGCGTCGATCAACAACCGCGTCTTCCGGACGATCGGTTCGCCACTCGTGCTGCCGGCGCATCATACGT
GTCTGCTAAAGCCTGTCAACAATGTCGATTTTCAAATTACGATCGACCATTTGTCACTATTGCACAAAGAGGTCAAATCG
ATTCAGTGCCGGGTCGCCGATGAAAAAGTGCGTTTCGCCCGCTTCCGACCGTTTCCGTTTTGGCGGCGGGTGCGTGATTC
GTTTATCGCTGACTGA

Upstream 100 bases:

>100_bases
CAGCCTACCGCCTTGATGAGGAAATGTCGAAAATACGCTTCGAGATTCAAGAAGCGCAAGCTGCTTTTTCACGAAAACAA
GAAGCAAAAGGGGAAGGGCA

Downstream 100 bases:

>100_bases
CAATAAATGTCCGATTGTTGTTGCCTGATCAGCGTTCAGCTGGCGTGCTGGAGTTGGATTAGCCCGCCGCCCAACGGCGA
AAATTTGCAACTATAGACAG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKRMDAPLAFAITSKGDDTSNALAQKMKTYLLDFDLRYDEEAPDLIISVGGDGTLLYAFHRYCHRLDKTAFVGIHTGHLG
FYADWVPEEIEKLVIAIAKTPYQVVEYPLLEVTIRYLNGGSEAKYLALNECTVKCVSGTLVMDVEIRGDLFERFRGDGLC
ISTPTGSTAYNKALGGAILHPSLEAIQVTEMASINNRVFRTIGSPLVLPAHHTCLLKPVNNVDFQITIDHLSLLHKEVKS
IQCRVADEKVRFARFRPFPFWRRVRDSFIAD

Sequences:

>Translated_271_residues
MKRMDAPLAFAITSKGDDTSNALAQKMKTYLLDFDLRYDEEAPDLIISVGGDGTLLYAFHRYCHRLDKTAFVGIHTGHLG
FYADWVPEEIEKLVIAIAKTPYQVVEYPLLEVTIRYLNGGSEAKYLALNECTVKCVSGTLVMDVEIRGDLFERFRGDGLC
ISTPTGSTAYNKALGGAILHPSLEAIQVTEMASINNRVFRTIGSPLVLPAHHTCLLKPVNNVDFQITIDHLSLLHKEVKS
IQCRVADEKVRFARFRPFPFWRRVRDSFIAD
>Mature_271_residues
MKRMDAPLAFAITSKGDDTSNALAQKMKTYLLDFDLRYDEEAPDLIISVGGDGTLLYAFHRYCHRLDKTAFVGIHTGHLG
FYADWVPEEIEKLVIAIAKTPYQVVEYPLLEVTIRYLNGGSEAKYLALNECTVKCVSGTLVMDVEIRGDLFERFRGDGLC
ISTPTGSTAYNKALGGAILHPSLEAIQVTEMASINNRVFRTIGSPLVLPAHHTCLLKPVNNVDFQITIDHLSLLHKEVKS
IQCRVADEKVRFARFRPFPFWRRVRDSFIAD

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=150, Percent_Identity=36, Blast_Score=71, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6320794, Length=206, Percent_Identity=28.1553398058252, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325068, Length=196, Percent_Identity=28.0612244897959, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 30454; Mature: 30454

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRMDAPLAFAITSKGDDTSNALAQKMKTYLLDFDLRYDEEAPDLIISVGGDGTLLYAFH
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEECCCCCCCCCEEEEECCCCEEHHHHH
RYCHRLDKTAFVGIHTGHLGFYADWVPEEIEKLVIAIAKTPYQVVEYPLLEVTIRYLNGG
HHHHHCCCEEEEEEEECCCCEEECCCHHHHHHHHHHHHCCCHHHHHCCHHHEEEEECCCC
SEAKYLALNECTVKCVSGTLVMDVEIRGDLFERFRGDGLCISTPTGSTAYNKALGGAILH
CCCEEEEECCCEEEEECCEEEEEEEECHHHHHHHCCCCEEEECCCCCCHHHHHCCCEEEC
PSLEAIQVTEMASINNRVFRTIGSPLVLPAHHTCLLKPVNNVDFQITIDHLSLLHKEVKS
CCCHHEEHHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHHHH
IQCRVADEKVRFARFRPFPFWRRVRDSFIAD
HEEEECCCHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKRMDAPLAFAITSKGDDTSNALAQKMKTYLLDFDLRYDEEAPDLIISVGGDGTLLYAFH
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEECCCCCCCCCEEEEECCCCEEHHHHH
RYCHRLDKTAFVGIHTGHLGFYADWVPEEIEKLVIAIAKTPYQVVEYPLLEVTIRYLNGG
HHHHHCCCEEEEEEEECCCCEEECCCHHHHHHHHHHHHCCCHHHHHCCHHHEEEEECCCC
SEAKYLALNECTVKCVSGTLVMDVEIRGDLFERFRGDGLCISTPTGSTAYNKALGGAILH
CCCEEEEECCCEEEEECCEEEEEEEECHHHHHHHCCCCEEEECCCCCCHHHHHCCCEEEC
PSLEAIQVTEMASINNRVFRTIGSPLVLPAHHTCLLKPVNNVDFQITIDHLSLLHKEVKS
CCCHHEEHHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHHHH
IQCRVADEKVRFARFRPFPFWRRVRDSFIAD
HEEEECCCHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA