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The map label for this gene is mecA [H]

Identifier: 138894371

GI number: 138894371

Start: 778154

End: 778834

Strand: Direct

Name: mecA [H]

Synonym: GTNG_0699

Alternate gene names: 138894371

Gene position: 778154-778834 (Clockwise)

Preceding gene: 138894369

Following gene: 138894372

Centisome position: 21.92

GC content: 44.79

Gene sequence:

>681_bases
ATGGAAATCGAACGTATCAATGATCATACGGTGAAATTTTACATTTCGTATGTTGATATAGAGGAGCGCGGTTTTGACCG
TGAAGAAATTTGGTATAATCGGGAACGAAGCGAAGAACTATTTTGGGAAATGATGGATGAGGTCCATAGCGAAAGTGATT
TTTCGCTCGACGGTCCGCTTTGGATTCAAGTGCAAGCATTGGAAAAAGGGCTTGAAGTTGTCGTGACGAAAGCGCAGTTG
TCCAAAGACGGGAGTAAGCTTGAGTTGCCGCTTCCGGAAGAAAGATGGCGTGAGTTTTCACTGTCAGCCGATGAGAAGCT
TGAGTCGTTGCTCAGCCATCATTTCCATTTTGGACGAAACAATGACGCCGAAGACGGCCAGGAGCAAGACGTTCTTCAAT
TTGTCATTTCGTTTAAAGACATCGAAGACGTGATCTCCTTGGCACATCGCGCTGATTTTTCCGGCCTGTCGAACCGCCTG
TTCCAGTTTGAAGGGCGTTACTATTTGTTTGTCGAATTTGGTGAACAATATACTGAGCATGACATAGACAATATGCTCAG
CCTTCTGTTGGAATACGGGAACGATTCGCAGCTGACGATTTATCGTCTAGAAGAATACGGGACCGAGATTATGAGCGATA
ATGCGCTTGAAACAGTAAAAAGATATTTTCCGGCCCCATAA

Upstream 100 bases:

>100_bases
TATAAATTACAAGATATGAGTTTTCATTAATAAATAAAATGTTTGAGGGCACGATCCCTTCCCTTTTTTATTTCTTTGTT
TAGAAGGGAGAGTTGAGAAG

Downstream 100 bases:

>100_bases
CGTCTCCATGCCGCCGATTTCGCTGCCAGAAATCGGCGTTTTCTTCGTTAATGAAGGGAAGGGTAGCCATCATGAAAAGC
AGGTGGAGGGGTTTCGTTGA

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEIERINDHTVKFYISYVDIEERGFDREEIWYNRERSEELFWEMMDEVHSESDFSLDGPLWIQVQALEKGLEVVVTKAQL
SKDGSKLELPLPEERWREFSLSADEKLESLLSHHFHFGRNNDAEDGQEQDVLQFVISFKDIEDVISLAHRADFSGLSNRL
FQFEGRYYLFVEFGEQYTEHDIDNMLSLLLEYGNDSQLTIYRLEEYGTEIMSDNALETVKRYFPAP

Sequences:

>Translated_226_residues
MEIERINDHTVKFYISYVDIEERGFDREEIWYNRERSEELFWEMMDEVHSESDFSLDGPLWIQVQALEKGLEVVVTKAQL
SKDGSKLELPLPEERWREFSLSADEKLESLLSHHFHFGRNNDAEDGQEQDVLQFVISFKDIEDVISLAHRADFSGLSNRL
FQFEGRYYLFVEFGEQYTEHDIDNMLSLLLEYGNDSQLTIYRLEEYGTEIMSDNALETVKRYFPAP
>Mature_226_residues
MEIERINDHTVKFYISYVDIEERGFDREEIWYNRERSEELFWEMMDEVHSESDFSLDGPLWIQVQALEKGLEVVVTKAQL
SKDGSKLELPLPEERWREFSLSADEKLESLLSHHFHFGRNNDAEDGQEQDVLQFVISFKDIEDVISLAHRADFSGLSNRL
FQFEGRYYLFVEFGEQYTEHDIDNMLSLLLEYGNDSQLTIYRLEEYGTEIMSDNALETVKRYFPAP

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 26776; Mature: 26776

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIERINDHTVKFYISYVDIEERGFDREEIWYNRERSEELFWEMMDEVHSESDFSLDGPL
CCCCCCCCCEEEEEEEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCE
WIQVQALEKGLEVVVTKAQLSKDGSKLELPLPEERWREFSLSADEKLESLLSHHFHFGRN
EEEHHHHHCCHHHEEEHHHHCCCCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCC
NDAEDGQEQDVLQFVISFKDIEDVISLAHRADFSGLSNRLFQFEGRYYLFVEFGEQYTEH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEECCCEEEEEECCCHHHHH
DIDNMLSLLLEYGNDSQLTIYRLEEYGTEIMSDNALETVKRYFPAP
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MEIERINDHTVKFYISYVDIEERGFDREEIWYNRERSEELFWEMMDEVHSESDFSLDGPL
CCCCCCCCCEEEEEEEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCE
WIQVQALEKGLEVVVTKAQLSKDGSKLELPLPEERWREFSLSADEKLESLLSHHFHFGRN
EEEHHHHHCCHHHEEEHHHHCCCCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCC
NDAEDGQEQDVLQFVISFKDIEDVISLAHRADFSGLSNRLFQFEGRYYLFVEFGEQYTEH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEECCCEEEEEECCCHHHHH
DIDNMLSLLLEYGNDSQLTIYRLEEYGTEIMSDNALETVKRYFPAP
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412687; 9384377 [H]