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The map label for this gene is cadC [H]

Identifier: 138894308

GI number: 138894308

Start: 710076

End: 710447

Strand: Direct

Name: cadC [H]

Synonym: GTNG_0636

Alternate gene names: 138894308

Gene position: 710076-710447 (Clockwise)

Preceding gene: 138894307

Following gene: 138894309

Centisome position: 20.0

GC content: 50.27

Gene sequence:

>372_bases
ATGCATCGCCCGGATGTGTGCGACGTCTACTGTTATGATGAAGAAAAGGTCGACCGTGTTCAGCGCCGGCTGCATGATGA
AAACATTGCCGCCATTGTGCCGTTTTTCAAGGCGCTGGCTGATGAAAACCGAGCGAAAATTGTATATGCGCTTTGCGGAG
AGGAAGAACTGTGCGTCTGTGATTTAGCGAATGTGATCGGGGCGACGGTGGCGACGACATCGCATCATTTGCGCATTTTG
TACAAACAAGGAATCGTGAAGTATCGAAAAGAGGGAAAACTCGCCTTTTACTCGCTTGATGACGAACATATTCGCGAGTT
GTTACTTGTGGCGCTTGCTCATCGGAAAGAGGGGGATGGCCGTGGCGAATGA

Upstream 100 bases:

>100_bases
AGGCACCTTTTTTCATTCAAATGAATATTTGAATATAAAAAAGAGATATGATACGCTATATTCAAATGGATGTTTGAATA
TTGGCGGGAGGAGAAAAGAC

Downstream 100 bases:

>100_bases
ACAGGCGTTGGAGCAACTCGAAACAAAAACGTATCGAGTGCAAGGGTTAACGTGTACAAACTGTGCCGCCAAGTTTGAGC
AAAATGTCAAAGCTTTGCCC

Product: cadmium efflux system accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MHRPDVCDVYCYDEEKVDRVQRRLHDENIAAIVPFFKALADENRAKIVYALCGEEELCVCDLANVIGATVATTSHHLRIL
YKQGIVKYRKEGKLAFYSLDDEHIRELLLVALAHRKEGDGRGE

Sequences:

>Translated_123_residues
MHRPDVCDVYCYDEEKVDRVQRRLHDENIAAIVPFFKALADENRAKIVYALCGEEELCVCDLANVIGATVATTSHHLRIL
YKQGIVKYRKEGKLAFYSLDDEHIRELLLVALAHRKEGDGRGE
>Mature_123_residues
MHRPDVCDVYCYDEEKVDRVQRRLHDENIAAIVPFFKALADENRAKIVYALCGEEELCVCDLANVIGATVATTSHHLRIL
YKQGIVKYRKEGKLAFYSLDDEHIRELLLVALAHRKEGDGRGE

Specific function: Metal-binding repressor for the cad operon. Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead. Metal binding causes the repressor to dissociate from the DNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 14072; Mature: 14072

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRPDVCDVYCYDEEKVDRVQRRLHDENIAAIVPFFKALADENRAKIVYALCGEEELCVC
CCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
DLANVIGATVATTSHHLRILYKQGIVKYRKEGKLAFYSLDDEHIRELLLVALAHRKEGDG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC
RGE
CCC
>Mature Secondary Structure
MHRPDVCDVYCYDEEKVDRVQRRLHDENIAAIVPFFKALADENRAKIVYALCGEEELCVC
CCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
DLANVIGATVATTSHHLRILYKQGIVKYRKEGKLAFYSLDDEHIRELLLVALAHRKEGDG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC
RGE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1321115 [H]