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The map label for this gene is yisQ [H]

Identifier: 138894282

GI number: 138894282

Start: 673721

End: 675073

Strand: Reverse

Name: yisQ [H]

Synonym: GTNG_0608

Alternate gene names: 138894282

Gene position: 675073-673721 (Counterclockwise)

Preceding gene: 138894284

Following gene: 138894280

Centisome position: 19.01

GC content: 51.22

Gene sequence:

>1353_bases
ATGCGCCGTGAGGCCAAAACGTGGTCACTGTTTTCATTGACGTGGCCCATTTTTATTGAAACGATGCTGTATATGGTGAT
GGGCAATGCTGACACGCTCATGCTCAGCCAGTACTCAGATCATGCGGTCGCTGCCGTCGGAGTTGCAAATCAAATCATCG
CCTTAACGATCGTGTTGTTCAACTTCGTTGCCTTGGCAACGGCAGTTCTCGTCGCGCAATATTTAGGCGCCAAGCGAGAA
CAAGAAGCGATCGAAGTATCACTTGTTTCCATCGCCGCTAACTTGTTGTTTGGACTGCTGTTGAGCGCTGGTTTGGCTGC
GTTTAGCTCATCGATTTTGCGGATGATGGATTTGCCGGCAGAGCTGCTTGATGAAGGGAACCGTTATTTAACCATTGTCG
GCGGATTTTCATTCATTCAGGCGCTCATGATGACGGTCGGTGCCATCTTGAAAAGCTACGGCTTTACGCGGGATACGATG
TATGTAACGATTGGCATGAACGTCTTGAATATCATCGGCAACTATTTCCTTATTTTCGGATCGTTTGGCCTCCCTCCCCT
CGGGGCGGAAGGAGCGGCCATTTCAACAGCAGTAAGCCGGCTGATCGGTTTTGCGGTGTTGGTTGCTTTATTGTCCAAAC
GAGCAGGCATTTCCCTTGCCCCGCGGGCGTTTCGTACGCTGCCGTTCCGCCATTTGCGCTCGTTGCTGAAAATTGGCGTT
CCAGCAGCCGGGGAACATCTTTCTTACAATACAGCGCAAATGGTCATCACCTACTTCATCACATGGCTTGGCGCTGAAGC
GCTAACCGTGAGGGTGTATACACAAAACATTATCATGTTCGTGTTTTTATTCGGCATTGCAGTCAGCCAAGGGACGCAAA
TTCTTGTCGGCCACTTCGTCGGCGCCGGACGGTACAAAGAAGCGTACGACCGCTGCTTAAAAAGCTTATACAGCGCAATC
GCTATATCAGTGCTAATGGCCGCTGTCACCTATTGGTTCGCCGAACCGTTGCTCTCACTCTTTACTGATGACCGGTCAAT
GATTGACCTTGGCCGCAAACTATTGCTGTTGACCATCATCCTAGAACCAGGCCGCTCCTTCAATCTAGTCATCGTCAGCT
CGCTCCGAGCGGCCGGGGATGTGCAATTCCCTGTCTATATGGGCATTTTGTCCATGTGGGGAGTCGGAGTGACGGTAGCG
TATGTATTTGGCATTGCCCTCGAGTTTGGCCTTGTCGGCATTTGGCTATCGTTCATCGCTGATGAATGGTTGCGCGGACT
ATTGATGCTTTGGCGATGGCGGTCGCGCATCTGGATGAAAAAAGCGGTGGCGCCGCAAGCGAAAATGGCATAG

Upstream 100 bases:

>100_bases
AATGCAAGTGAAATCGTTTCTCTCTCTTTCCATTATGCAACAAACTGGCTAAACTTGATATATCGTTCTAGTCGGAATAA
GAAAAAGGAGTTGTCACAAC

Downstream 100 bases:

>100_bases
TACTGCTCTCTTTGCTATTCAATAGAATAAGAGCTGCGTCCTCACGCAGCTCTTATTCTTTAATATGAATGCCGTAATGG
TCAAACCAAACATGCACCTG

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRREAKTWSLFSLTWPIFIETMLYMVMGNADTLMLSQYSDHAVAAVGVANQIIALTIVLFNFVALATAVLVAQYLGAKRE
QEAIEVSLVSIAANLLFGLLLSAGLAAFSSSILRMMDLPAELLDEGNRYLTIVGGFSFIQALMMTVGAILKSYGFTRDTM
YVTIGMNVLNIIGNYFLIFGSFGLPPLGAEGAAISTAVSRLIGFAVLVALLSKRAGISLAPRAFRTLPFRHLRSLLKIGV
PAAGEHLSYNTAQMVITYFITWLGAEALTVRVYTQNIIMFVFLFGIAVSQGTQILVGHFVGAGRYKEAYDRCLKSLYSAI
AISVLMAAVTYWFAEPLLSLFTDDRSMIDLGRKLLLLTIILEPGRSFNLVIVSSLRAAGDVQFPVYMGILSMWGVGVTVA
YVFGIALEFGLVGIWLSFIADEWLRGLLMLWRWRSRIWMKKAVAPQAKMA

Sequences:

>Translated_450_residues
MRREAKTWSLFSLTWPIFIETMLYMVMGNADTLMLSQYSDHAVAAVGVANQIIALTIVLFNFVALATAVLVAQYLGAKRE
QEAIEVSLVSIAANLLFGLLLSAGLAAFSSSILRMMDLPAELLDEGNRYLTIVGGFSFIQALMMTVGAILKSYGFTRDTM
YVTIGMNVLNIIGNYFLIFGSFGLPPLGAEGAAISTAVSRLIGFAVLVALLSKRAGISLAPRAFRTLPFRHLRSLLKIGV
PAAGEHLSYNTAQMVITYFITWLGAEALTVRVYTQNIIMFVFLFGIAVSQGTQILVGHFVGAGRYKEAYDRCLKSLYSAI
AISVLMAAVTYWFAEPLLSLFTDDRSMIDLGRKLLLLTIILEPGRSFNLVIVSSLRAAGDVQFPVYMGILSMWGVGVTVA
YVFGIALEFGLVGIWLSFIADEWLRGLLMLWRWRSRIWMKKAVAPQAKMA
>Mature_450_residues
MRREAKTWSLFSLTWPIFIETMLYMVMGNADTLMLSQYSDHAVAAVGVANQIIALTIVLFNFVALATAVLVAQYLGAKRE
QEAIEVSLVSIAANLLFGLLLSAGLAAFSSSILRMMDLPAELLDEGNRYLTIVGGFSFIQALMMTVGAILKSYGFTRDTM
YVTIGMNVLNIIGNYFLIFGSFGLPPLGAEGAAISTAVSRLIGFAVLVALLSKRAGISLAPRAFRTLPFRHLRSLLKIGV
PAAGEHLSYNTAQMVITYFITWLGAEALTVRVYTQNIIMFVFLFGIAVSQGTQILVGHFVGAGRYKEAYDRCLKSLYSAI
AISVLMAAVTYWFAEPLLSLFTDDRSMIDLGRKLLLLTIILEPGRSFNLVIVSSLRAAGDVQFPVYMGILSMWGVGVTVA
YVFGIALEFGLVGIWLSFIADEWLRGLLMLWRWRSRIWMKKAVAPQAKMA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=441, Percent_Identity=26.984126984127, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI48994890, Length=447, Percent_Identity=23.489932885906, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49437; Mature: 49437

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRREAKTWSLFSLTWPIFIETMLYMVMGNADTLMLSQYSDHAVAAVGVANQIIALTIVLF
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
NFVALATAVLVAQYLGAKREQEAIEVSLVSIAANLLFGLLLSAGLAAFSSSILRMMDLPA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ELLDEGNRYLTIVGGFSFIQALMMTVGAILKSYGFTRDTMYVTIGMNVLNIIGNYFLIFG
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHC
SFGLPPLGAEGAAISTAVSRLIGFAVLVALLSKRAGISLAPRAFRTLPFRHLRSLLKIGV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHCCC
PAAGEHLSYNTAQMVITYFITWLGAEALTVRVYTQNIIMFVFLFGIAVSQGTQILVGHFV
CCCCCCCCCHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
GAGRYKEAYDRCLKSLYSAIAISVLMAAVTYWFAEPLLSLFTDDRSMIDLGRKLLLLTII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LEPGRSFNLVIVSSLRAAGDVQFPVYMGILSMWGVGVTVAYVFGIALEFGLVGIWLSFIA
CCCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEWLRGLLMLWRWRSRIWMKKAVAPQAKMA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRREAKTWSLFSLTWPIFIETMLYMVMGNADTLMLSQYSDHAVAAVGVANQIIALTIVLF
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
NFVALATAVLVAQYLGAKREQEAIEVSLVSIAANLLFGLLLSAGLAAFSSSILRMMDLPA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ELLDEGNRYLTIVGGFSFIQALMMTVGAILKSYGFTRDTMYVTIGMNVLNIIGNYFLIFG
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHC
SFGLPPLGAEGAAISTAVSRLIGFAVLVALLSKRAGISLAPRAFRTLPFRHLRSLLKIGV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHCCC
PAAGEHLSYNTAQMVITYFITWLGAEALTVRVYTQNIIMFVFLFGIAVSQGTQILVGHFV
CCCCCCCCCHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
GAGRYKEAYDRCLKSLYSAIAISVLMAAVTYWFAEPLLSLFTDDRSMIDLGRKLLLLTII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LEPGRSFNLVIVSSLRAAGDVQFPVYMGILSMWGVGVTVAYVFGIALEFGLVGIWLSFIA
CCCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEWLRGLLMLWRWRSRIWMKKAVAPQAKMA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]