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The map label for this gene is lepB [H]

Identifier: 138894261

GI number: 138894261

Start: 648671

End: 649225

Strand: Direct

Name: lepB [H]

Synonym: GTNG_0587

Alternate gene names: 138894261

Gene position: 648671-649225 (Clockwise)

Preceding gene: 138894260

Following gene: 138894262

Centisome position: 18.27

GC content: 45.59

Gene sequence:

>555_bases
ATGACGAAAGAAAAGAAAAAGGAAAAACGGAGATATCATTGGCCATGGCTGACCGTCGTTTGCTTCATCGTGGCGCTCCG
TTTTTTTGTTTTCAGCAGCTACATGGTAGAGGGAAAATCGATGATGCCGACGCTGCAAAGCGGCAATTTGCTGATTGTCA
ATAAACTGTCCTACGAAATCGGATCGATCCGCCGATTTGACATTGTCGTTTTTCATGCCAACCAAAAGGAGGATTATGTA
AAGCGGGTTATTGGGCTGCCGGGGGACCGGATTGAATATAAAAACGATATATTGTATGTCAATGGAAAAAAAGTTGACGA
ACCATATTTACGACCGTATAAGAAAAAATTGATTAGCGGCAAGCTGACGGGCGATTTTACCCTTGAAGAGGTGACCGGAG
AAAGACGAGTGCCGGCCGGTTGCATTTTCGTGCTTGGCGATAATCGGCTTGGCAGTTGGGACAGCCGCCATTTCGGTTTT
GTCAAAATCGATCAGGTCGTCGGCAAGGTCGATCTTCGTTATTGGCCGTTTGAACAGTTTGCTTTCCGTTTTTAG

Upstream 100 bases:

>100_bases
CTGGAATTGCTTTGGTTGTTTTGTTGCTTTGGTATGCAGGAAAACGGGTAGAAGCAAGATTTTCGCTGACAGAAAAACAA
CATGGCGAGGGGGGTGGGGA

Downstream 100 bases:

>100_bases
GACAGCGACTTGCAAAACTCGGTTGTCGGAGCGCCAGCTAGAGAAAAACTTTATTTCTTTGCCGAAATTTGCCGTCCGAA
GCCCATGATTGGAAACGTGA

Product: Signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MTKEKKKEKRRYHWPWLTVVCFIVALRFFVFSSYMVEGKSMMPTLQSGNLLIVNKLSYEIGSIRRFDIVVFHANQKEDYV
KRVIGLPGDRIEYKNDILYVNGKKVDEPYLRPYKKKLISGKLTGDFTLEEVTGERRVPAGCIFVLGDNRLGSWDSRHFGF
VKIDQVVGKVDLRYWPFEQFAFRF

Sequences:

>Translated_184_residues
MTKEKKKEKRRYHWPWLTVVCFIVALRFFVFSSYMVEGKSMMPTLQSGNLLIVNKLSYEIGSIRRFDIVVFHANQKEDYV
KRVIGLPGDRIEYKNDILYVNGKKVDEPYLRPYKKKLISGKLTGDFTLEEVTGERRVPAGCIFVLGDNRLGSWDSRHFGF
VKIDQVVGKVDLRYWPFEQFAFRF
>Mature_183_residues
TKEKKKEKRRYHWPWLTVVCFIVALRFFVFSSYMVEGKSMMPTLQSGNLLIVNKLSYEIGSIRRFDIVVFHANQKEDYVK
RVIGLPGDRIEYKNDILYVNGKKVDEPYLRPYKKKLISGKLTGDFTLEEVTGERRVPAGCIFVLGDNRLGSWDSRHFGFV
KIDQVVGKVDLRYWPFEQFAFRF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=89, Percent_Identity=35.9550561797753, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21676; Mature: 21544

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEKKKEKRRYHWPWLTVVCFIVALRFFVFSSYMVEGKSMMPTLQSGNLLIVNKLSYEI
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEECCCCC
GSIRRFDIVVFHANQKEDYVKRVIGLPGDRIEYKNDILYVNGKKVDEPYLRPYKKKLISG
CCEEEEEEEEEECCCHHHHHHHHHCCCCCCEEECCCEEEECCCCCCCHHHHHHHHHHHCC
KLTGDFTLEEVTGERRVPAGCIFVLGDNRLGSWDSRHFGFVKIDQVVGKVDLRYWPFEQF
CCCCCEEHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHCCEECCHHHH
AFRF
HCCC
>Mature Secondary Structure 
TKEKKKEKRRYHWPWLTVVCFIVALRFFVFSSYMVEGKSMMPTLQSGNLLIVNKLSYEI
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEECCCCC
GSIRRFDIVVFHANQKEDYVKRVIGLPGDRIEYKNDILYVNGKKVDEPYLRPYKKKLISG
CCEEEEEEEEEECCCHHHHHHHHHCCCCCCEEECCCEEEECCCCCCCHHHHHHHHHHHCC
KLTGDFTLEEVTGERRVPAGCIFVLGDNRLGSWDSRHFGFVKIDQVVGKVDLRYWPFEQF
CCCCCEEHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHCCEECCHHHH
AFRF
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]