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The map label for this gene is hit [H]

Identifier: 138894239

GI number: 138894239

Start: 625306

End: 625740

Strand: Reverse

Name: hit [H]

Synonym: GTNG_0565

Alternate gene names: 138894239

Gene position: 625740-625306 (Counterclockwise)

Preceding gene: 138894253

Following gene: 138894236

Centisome position: 17.62

GC content: 51.26

Gene sequence:

>435_bases
GTGACCGTTTCCGTGAGCGATTGCATTTTTTGCAAAATTATTAAGGGCGAACTGCCGGCGGCGAAAGTGTACGAAGACGA
GCACGTGCTCGCATTTTTAGACATCAGCCAAGTGACAAAAGGGCATACGCTTGTCATCCCGAAAGTACATACAGAAAACG
TTTTTACCCTCACTCCTGATATGGCCAGTCGGCTGTTTAGCGTCGTACCGACGATCGCCAACGCATTGAATAAAACGTTC
TCACCAGCCGGGCTCAATTTGCTGAACAACAATGGCGAAGCAGCCGGGCAAACGGTGTTCCATTACCATCTCCACCTTAT
TCCGCGCTATGGCAAAGGCGACGGGTTCGGAGCTGTTTGGAAGTCACATGCAAGCGACTATACGCCTGCCGACTTGCAAG
CGATCGCCGCCACAATCCGCGAACAGCTCAACTAA

Upstream 100 bases:

>100_bases
TTGAATGATCCTCTCCCCTTTTCATCGACCGGGATGTAATCGTTTCACGGGATTACATCCCGGTTTTTTTATGGTAAAAT
GAAGAAAACGAAAGGAAAGG

Downstream 100 bases:

>100_bases
AAAACCGGAAGCAGGGGTTTCCTGCTCCCGGTTTTTATTGTTGCTCAAGCACATCTTGCAAATCTTTGTCTTTGATCTTG
ACATTAGCATCTTTCACAAG

Product: bis(5'-nucleosyl)-tetraphosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MTVSVSDCIFCKIIKGELPAAKVYEDEHVLAFLDISQVTKGHTLVIPKVHTENVFTLTPDMASRLFSVVPTIANALNKTF
SPAGLNLLNNNGEAAGQTVFHYHLHLIPRYGKGDGFGAVWKSHASDYTPADLQAIAATIREQLN

Sequences:

>Translated_144_residues
MTVSVSDCIFCKIIKGELPAAKVYEDEHVLAFLDISQVTKGHTLVIPKVHTENVFTLTPDMASRLFSVVPTIANALNKTF
SPAGLNLLNNNGEAAGQTVFHYHLHLIPRYGKGDGFGAVWKSHASDYTPADLQAIAATIREQLN
>Mature_143_residues
TVSVSDCIFCKIIKGELPAAKVYEDEHVLAFLDISQVTKGHTLVIPKVHTENVFTLTPDMASRLFSVVPTIANALNKTFS
PAGLNLLNNNGEAAGQTVFHYHLHLIPRYGKGDGFGAVWKSHASDYTPADLQAIAATIREQLN

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=102, Percent_Identity=36.2745098039216, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17506713, Length=105, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=120, Percent_Identity=38.3333333333333, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15676; Mature: 15545

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSVSDCIFCKIIKGELPAAKVYEDEHVLAFLDISQVTKGHTLVIPKVHTENVFTLTPD
CCCCCCCEEEEEEECCCCCCCEEECCCCEEEEEEHHHHCCCCEEEEEEECCCCEEEECHH
MASRLFSVVPTIANALNKTFSPAGLNLLNNNGEAAGQTVFHYHLHLIPRYGKGDGFGAVW
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEEEEEECCCCCCCCHHHH
KSHASDYTPADLQAIAATIREQLN
HCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVSVSDCIFCKIIKGELPAAKVYEDEHVLAFLDISQVTKGHTLVIPKVHTENVFTLTPD
CCCCCCEEEEEEECCCCCCCEEECCCCEEEEEEHHHHCCCCEEEEEEECCCCEEEECHH
MASRLFSVVPTIANALNKTFSPAGLNLLNNNGEAAGQTVFHYHLHLIPRYGKGDGFGAVW
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEEEEEECCCCCCCCHHHH
KSHASDYTPADLQAIAATIREQLN
HCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]