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The map label for this gene is yhdP [H]

Identifier: 138894181

GI number: 138894181

Start: 571098

End: 572450

Strand: Direct

Name: yhdP [H]

Synonym: GTNG_0507

Alternate gene names: 138894181

Gene position: 571098-572450 (Clockwise)

Preceding gene: 138894180

Following gene: 138894183

Centisome position: 16.09

GC content: 45.08

Gene sequence:

>1353_bases
TTGGACATAGCCAGTTTGCTGTTAGTGGCATTGCTCATCGCTTGCACCGCCTTTTTCGTCGCTTCGGAATTTGCGATCGT
CAAAGTGCGCAGTTCGCGCATCGACCAACTTGTTAATGAAGGAAATAAACAGGCGGTGGCGGCGAAAAAAGTGATTTCGA
ATTTGGACGGTTATTTATCGGCGAACCAGCTTGGCATTACTCTTACTTCACTTGGCCTTGGTTGGCTTGGGGAGCCGACG
GTGGCGCGGATGTTGCTGCCGCTGTTTGAACGCCTCCATTTATCGGAATCCGTCTCCCACTTTTTAGCGTTTATTATTTC
ATTTTCACTCATTACGTTTTTGCACGTTGTTGTCGGTGAATTGGCGCCGAAAACGTTTGCCATTCATAAGGCGGAAGCGA
TTACGTTGTGGACAGCCAAGCCGCTTATTTGGTTTTACAAAATCATGTATCCGTTCATTTGGACACTCAACAATTCTGCG
CGGCTCGTGACACGCCTGTTCGGCCTTAGGCCGGTGGCCGAGCATGAAATCGCCCACTCCGAAGAAGAGTTGCGTTTGAT
TTTATCGGAAAGTTACAAAAGTGGGGAAATTAACCAATCTGAGTACCGCTATGTTAACAACATTTTTCGTTTTGACGACC
GTGTGGCCAAAGAAATTATGGTACCGCGTAAAGAAATTGTGGCGTTAGACATTAACAAGAGCGTCAAGGAGAATTTAGCC
ATCATTCAAGAAGAAAAATATACGCGTTACCCAGTTATCGATGGAGATAAAGACCATGTACTCGGGCTCATTAATGTAAA
AGAAGTATTTACAGATTTTGTTGCTAACCCGTCAAACGAAAAACAAATGAAAGATTACATCCGTCCGATTATTCAAGTCA
TTGAATCGATCGCCATTCATGACTTGCTCGTAAAAATGCAAAAAGAGCGCATCCACATGGCGATTTTAGTGGACGAGTAT
GGCGGTACGTCCGGACTTGTTACGGTCGAGGACATTTTGGAAGAGATTGTTGGCGAGATTCAAGATGAGTTCGACATTGA
TGAAACGCCTTTGATCCAAAAAATTGATGACCGATTTATTTTGGATGGTAAAGTGCTCATTGGCGAAGTGAATGACTTGT
TGGGGCTAGAGCTTGATGATGACGATGTCGATACGATTGGCGGTTGGGTTTTGACGAAATATTACGACATTCAGACGGGT
GACAGTGTGGAAATTGATGGTTATCTCTTTACGGTGAAAGAAATGGATGGCCATCATGTCAAGACGTTGGAAGTGGTGAA
AAAAGAACCAAAGCCGGATGAAGAGGAAAGCGAGCCGGCGGATGCGGGGGAAGAGGAGCAGTTGCGCTTGTAA

Upstream 100 bases:

>100_bases
GTTGGCGGCCGTTCGGCGGCATTACTGTCTATAGGGTGCTGTTGAAACTTTTATTCGCAGGAGGTGTAACCTGGGCGCTC
CATCCGCGCTCAGAGACAAA

Downstream 100 bases:

>100_bases
GGCAGACGGGAGAACCGTCTGCCTTTTTATCATCTTTATCGACCACATCTCCATCCCAAGCAAAAACAGGGAGCGCTCAA
TGGTAAATGTGTGAGAGATC

Product: magnesium and cobalt efflux protein CorC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MDIASLLLVALLIACTAFFVASEFAIVKVRSSRIDQLVNEGNKQAVAAKKVISNLDGYLSANQLGITLTSLGLGWLGEPT
VARMLLPLFERLHLSESVSHFLAFIISFSLITFLHVVVGELAPKTFAIHKAEAITLWTAKPLIWFYKIMYPFIWTLNNSA
RLVTRLFGLRPVAEHEIAHSEEELRLILSESYKSGEINQSEYRYVNNIFRFDDRVAKEIMVPRKEIVALDINKSVKENLA
IIQEEKYTRYPVIDGDKDHVLGLINVKEVFTDFVANPSNEKQMKDYIRPIIQVIESIAIHDLLVKMQKERIHMAILVDEY
GGTSGLVTVEDILEEIVGEIQDEFDIDETPLIQKIDDRFILDGKVLIGEVNDLLGLELDDDDVDTIGGWVLTKYYDIQTG
DSVEIDGYLFTVKEMDGHHVKTLEVVKKEPKPDEEESEPADAGEEEQLRL

Sequences:

>Translated_450_residues
MDIASLLLVALLIACTAFFVASEFAIVKVRSSRIDQLVNEGNKQAVAAKKVISNLDGYLSANQLGITLTSLGLGWLGEPT
VARMLLPLFERLHLSESVSHFLAFIISFSLITFLHVVVGELAPKTFAIHKAEAITLWTAKPLIWFYKIMYPFIWTLNNSA
RLVTRLFGLRPVAEHEIAHSEEELRLILSESYKSGEINQSEYRYVNNIFRFDDRVAKEIMVPRKEIVALDINKSVKENLA
IIQEEKYTRYPVIDGDKDHVLGLINVKEVFTDFVANPSNEKQMKDYIRPIIQVIESIAIHDLLVKMQKERIHMAILVDEY
GGTSGLVTVEDILEEIVGEIQDEFDIDETPLIQKIDDRFILDGKVLIGEVNDLLGLELDDDDVDTIGGWVLTKYYDIQTG
DSVEIDGYLFTVKEMDGHHVKTLEVVKKEPKPDEEESEPADAGEEEQLRL
>Mature_450_residues
MDIASLLLVALLIACTAFFVASEFAIVKVRSSRIDQLVNEGNKQAVAAKKVISNLDGYLSANQLGITLTSLGLGWLGEPT
VARMLLPLFERLHLSESVSHFLAFIISFSLITFLHVVVGELAPKTFAIHKAEAITLWTAKPLIWFYKIMYPFIWTLNNSA
RLVTRLFGLRPVAEHEIAHSEEELRLILSESYKSGEINQSEYRYVNNIFRFDDRVAKEIMVPRKEIVALDINKSVKENLA
IIQEEKYTRYPVIDGDKDHVLGLINVKEVFTDFVANPSNEKQMKDYIRPIIQVIESIAIHDLLVKMQKERIHMAILVDEY
GGTSGLVTVEDILEEIVGEIQDEFDIDETPLIQKIDDRFILDGKVLIGEVNDLLGLELDDDDVDTIGGWVLTKYYDIQTG
DSVEIDGYLFTVKEMDGHHVKTLEVVKKEPKPDEEESEPADAGEEEQLRL

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=404, Percent_Identity=49.009900990099, Blast_Score=396, Evalue=1e-110,
Organism=Escherichia coli, GI1790664, Length=449, Percent_Identity=24.0534521158129, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI145693175, Length=421, Percent_Identity=26.8408551068884, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786879, Length=279, Percent_Identity=31.1827956989247, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788119, Length=245, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082033, Length=235, Percent_Identity=25.9574468085106, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50946; Mature: 50946

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIASLLLVALLIACTAFFVASEFAIVKVRSSRIDQLVNEGNKQAVAAKKVISNLDGYLS
CCHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
ANQLGITLTSLGLGWLGEPTVARMLLPLFERLHLSESVSHFLAFIISFSLITFLHVVVGE
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTFAIHKAEAITLWTAKPLIWFYKIMYPFIWTLNNSARLVTRLFGLRPVAEHEIAHS
HCCCCEEEECCCEEEEEECHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCHHHHHHHCC
EEELRLILSESYKSGEINQSEYRYVNNIFRFDDRVAKEIMVPRKEIVALDINKSVKENLA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCHHHHHHHH
IIQEEKYTRYPVIDGDKDHVLGLINVKEVFTDFVANPSNEKQMKDYIRPIIQVIESIAIH
HHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
DLLVKMQKERIHMAILVDEYGGTSGLVTVEDILEEIVGEIQDEFDIDETPLIQKIDDRFI
HHHHHHHHCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEE
LDGKVLIGEVNDLLGLELDDDDVDTIGGWVLTKYYDIQTGDSVEIDGYLFTVKEMDGHHV
ECCEEEEEEHHHHHCCCCCCCCHHHHCCEEEEEEEEECCCCCEEECEEEEEEEECCCCCH
KTLEVVKKEPKPDEEESEPADAGEEEQLRL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDIASLLLVALLIACTAFFVASEFAIVKVRSSRIDQLVNEGNKQAVAAKKVISNLDGYLS
CCHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
ANQLGITLTSLGLGWLGEPTVARMLLPLFERLHLSESVSHFLAFIISFSLITFLHVVVGE
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTFAIHKAEAITLWTAKPLIWFYKIMYPFIWTLNNSARLVTRLFGLRPVAEHEIAHS
HCCCCEEEECCCEEEEEECHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCHHHHHHHCC
EEELRLILSESYKSGEINQSEYRYVNNIFRFDDRVAKEIMVPRKEIVALDINKSVKENLA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCHHHHHHHH
IIQEEKYTRYPVIDGDKDHVLGLINVKEVFTDFVANPSNEKQMKDYIRPIIQVIESIAIH
HHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
DLLVKMQKERIHMAILVDEYGGTSGLVTVEDILEEIVGEIQDEFDIDETPLIQKIDDRFI
HHHHHHHHCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEE
LDGKVLIGEVNDLLGLELDDDDVDTIGGWVLTKYYDIQTGDSVEIDGYLFTVKEMDGHHV
ECCEEEEEEHHHHHCCCCCCCCHHHHCCEEEEEEEEECCCCCEEECEEEEEEEECCCCCH
KTLEVVKKEPKPDEEESEPADAGEEEQLRL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]