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The map label for this gene is ykvZ [H]

Identifier: 138894174

GI number: 138894174

Start: 563084

End: 564061

Strand: Direct

Name: ykvZ [H]

Synonym: GTNG_0500

Alternate gene names: 138894174

Gene position: 563084-564061 (Clockwise)

Preceding gene: 138894172

Following gene: 138894177

Centisome position: 15.86

GC content: 48.26

Gene sequence:

>978_bases
GTGGCGAACATCCGTGATTTGGCGAAAGAAGCGGGTGTGTCAGTATCTACCGTATCAAGGGTATTAAACGGGTATCCATA
TGTGAGTGAGGAAAAGCGGAAGGCAGTTTGGGAAGCAGTTGAGAAGCTCAATTATACAAAAAACATCCAAGCCGTTCATT
TGGCAAAAGGAAGGACAATGATTGTCGGAGTCATGCTTCCGTACATTCATCATCCTTATTTTTCAGCGGTCATTGAAGGG
ATTTCCAAAGAGGCGCTTCGTTATGGTTATCAGTTGCTTTTGTTTCAGACGAATTATGACGTAGAGCGGGAACTCGAGGT
GTTAGAGCGGTTGCGAATGAAGCAAATGGATGGCTTGATTGTCTGTTCTCATGAAGTGGGATGGGAAATTTTTGACGCAT
ACCAAGAAGAGGCCCCCATCGTTTTATGCGAGCAAGTGACAGAATATGATTTTTTCACGGTCTATATCGACCACTATCAA
GCGTTCGCCAAAGCTCTTCACTATTTGGTGAAAAAAGGACATCGACGGATTGGCTATTGCATCGGGAGAAGGACAGGACC
GAACAGCCAAGCGCGAGAAGCGGCGTATCAAGATGTGTTGCGTGATGTCGGCGTTACGCCCCAGCGCCAATGGATTTTTG
ACGGCTGTCTATTTCTTGAAGACGGAAAACGCGTGATCGAACAATGGATGGCAATGGAAGAGCGTCCGAGTGCATTGCTT
GTAACGAGCGACCAAGTGGCAGCCGGTATCGTATTGGAGGCACGACGCATCGGGGTGCGCATTCCAGAAGAGCTTACTAT
CATCGGGTTTGATAATGATCCGCTGGCCGAAATGTTGGGCATTACGACAGTGGCACTCCCTCATTTTACGTTGGGGGAAA
AAGCGTTTCGGCTTCTTCACCATTGGCTGGAGACAGGAAATGTTCCTCGAAAACAAGAAGAGTTGCCTACCCGGTTGGTC
GTGCGGGCTACCGGGTAA

Upstream 100 bases:

>100_bases
TGAAGCATATGAACCCCTCCTTTTGTATACTAGATGGTGAAATCAACATAATGGATGAAACGCGTTTCAAGTCAAGCGTT
TTTTAGGAAGGGGTGGGAAC

Downstream 100 bases:

>100_bases
GCTATATTCGTTTCAACTGATAGCGGTTGACGGGGCGACCAATACTGCCATATTGCACATCGAGCACAACCTTTCCACTT
TTCTCAAGGTATTCTAAGTA

Product: LacI family sugar-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MANIRDLAKEAGVSVSTVSRVLNGYPYVSEEKRKAVWEAVEKLNYTKNIQAVHLAKGRTMIVGVMLPYIHHPYFSAVIEG
ISKEALRYGYQLLLFQTNYDVERELEVLERLRMKQMDGLIVCSHEVGWEIFDAYQEEAPIVLCEQVTEYDFFTVYIDHYQ
AFAKALHYLVKKGHRRIGYCIGRRTGPNSQAREAAYQDVLRDVGVTPQRQWIFDGCLFLEDGKRVIEQWMAMEERPSALL
VTSDQVAAGIVLEARRIGVRIPEELTIIGFDNDPLAEMLGITTVALPHFTLGEKAFRLLHHWLETGNVPRKQEELPTRLV
VRATG

Sequences:

>Translated_325_residues
MANIRDLAKEAGVSVSTVSRVLNGYPYVSEEKRKAVWEAVEKLNYTKNIQAVHLAKGRTMIVGVMLPYIHHPYFSAVIEG
ISKEALRYGYQLLLFQTNYDVERELEVLERLRMKQMDGLIVCSHEVGWEIFDAYQEEAPIVLCEQVTEYDFFTVYIDHYQ
AFAKALHYLVKKGHRRIGYCIGRRTGPNSQAREAAYQDVLRDVGVTPQRQWIFDGCLFLEDGKRVIEQWMAMEERPSALL
VTSDQVAAGIVLEARRIGVRIPEELTIIGFDNDPLAEMLGITTVALPHFTLGEKAFRLLHHWLETGNVPRKQEELPTRLV
VRATG
>Mature_324_residues
ANIRDLAKEAGVSVSTVSRVLNGYPYVSEEKRKAVWEAVEKLNYTKNIQAVHLAKGRTMIVGVMLPYIHHPYFSAVIEGI
SKEALRYGYQLLLFQTNYDVERELEVLERLRMKQMDGLIVCSHEVGWEIFDAYQEEAPIVLCEQVTEYDFFTVYIDHYQA
FAKALHYLVKKGHRRIGYCIGRRTGPNSQAREAAYQDVLRDVGVTPQRQWIFDGCLFLEDGKRVIEQWMAMEERPSALLV
TSDQVAAGIVLEARRIGVRIPEELTIIGFDNDPLAEMLGITTVALPHFTLGEKAFRLLHHWLETGNVPRKQEELPTRLVV
RATG

Specific function: This Protein Negatively Controls The Transcription Initiation Of Genes Such As Deocabd, Udp, And Cdd Encoding Catabolizing Enzymes And Nupc, Nupg, And Tsx Encoding Transporting And Pore-Forming Proteins. Binds Cytidine And Adenosine As Effectors. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=30, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1787948, Length=305, Percent_Identity=31.1475409836066, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1788474, Length=327, Percent_Identity=29.3577981651376, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=26.6666666666667, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789068, Length=296, Percent_Identity=30.0675675675676, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=27.1812080536913, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI48994940, Length=303, Percent_Identity=26.4026402640264, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=26.1682242990654, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789456, Length=342, Percent_Identity=26.0233918128655, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786268, Length=331, Percent_Identity=25.3776435045317, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787906, Length=250, Percent_Identity=24, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786540, Length=332, Percent_Identity=25, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790715, Length=303, Percent_Identity=22.7722772277228, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37183; Mature: 37052

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIRDLAKEAGVSVSTVSRVLNGYPYVSEEKRKAVWEAVEKLNYTKNIQAVHLAKGRTM
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCEE
IVGVMLPYIHHPYFSAVIEGISKEALRYGYQLLLFQTNYDVERELEVLERLRMKQMDGLI
EHHHHHHHHHCHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEE
VCSHEVGWEIFDAYQEEAPIVLCEQVTEYDFFTVYIDHYQAFAKALHYLVKKGHRRIGYC
EEECCCCHHHHHHHHHCCCEEEEHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHH
IGRRTGPNSQAREAAYQDVLRDVGVTPQRQWIFDGCLFLEDGKRVIEQWMAMEERPSALL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEECCCHHHHHHHHHHHCCCCEEE
VTSDQVAAGIVLEARRIGVRIPEELTIIGFDNDPLAEMLGITTVALPHFTLGEKAFRLLH
EECCCHHHHHHEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
HWLETGNVPRKQEELPTRLVVRATG
HHHHCCCCCCHHHHCCCEEEEEECC
>Mature Secondary Structure 
ANIRDLAKEAGVSVSTVSRVLNGYPYVSEEKRKAVWEAVEKLNYTKNIQAVHLAKGRTM
CCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCEE
IVGVMLPYIHHPYFSAVIEGISKEALRYGYQLLLFQTNYDVERELEVLERLRMKQMDGLI
EHHHHHHHHHCHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEE
VCSHEVGWEIFDAYQEEAPIVLCEQVTEYDFFTVYIDHYQAFAKALHYLVKKGHRRIGYC
EEECCCCHHHHHHHHHCCCEEEEHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHH
IGRRTGPNSQAREAAYQDVLRDVGVTPQRQWIFDGCLFLEDGKRVIEQWMAMEERPSALL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEECCCHHHHHHHHHHHCCCCEEE
VTSDQVAAGIVLEARRIGVRIPEELTIIGFDNDPLAEMLGITTVALPHFTLGEKAFRLLH
EECCCHHHHHHEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
HWLETGNVPRKQEELPTRLVVRATG
HHHHCCCCCCHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]