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The map label for this gene is sstT

Identifier: 138893991

GI number: 138893991

Start: 358300

End: 359532

Strand: Reverse

Name: sstT

Synonym: GTNG_0317

Alternate gene names: 138893991

Gene position: 359532-358300 (Counterclockwise)

Preceding gene: 138893994

Following gene: 138893980

Centisome position: 10.13

GC content: 46.55

Gene sequence:

>1233_bases
ATGAAGCAACTCATTGCCAAATGGAATCGAGTCAGCCTCGTCAAACGTATCATTATCGGCATCATCATCGGGATTACACT
TGCAGTTACCGTTCCGGAATCGACAAAATGGATTTCCATTTTCGGTTCGTTATTTGTTGGCGCTCTAAAGGCGGTCGCGC
CTGTATTAGTGTTCTTTCTCGTGATCTCAGCCATTTCTCGGCATCAAAGCGGACAAAAAACAAATATTCAACATATTCTG
ATTCTATACGGGTTTAGCACGTTCCTAGCCAGTCTCACTGCCGTCGTAGCCAGCTTTCTCTTTCCGGTTCATTTATCGTT
AACCGAAAGCGCAAAAGAGGTTTCTCCTCCTAGCAACATAACGGAAGTGATTCAATCATTGCTGTTTAATATTGTCGATA
ACCCTGTTCACGCCTTACTGAATGCGAACTATATCGGCATTTTGACATGGGCTGTATTGCTTGGCATCGCATTAAGGACG
GCGCCGGAGACAACCAAAAATGTCATCGCTCATTTCTCTGACGCCATCTCGCAAATTGTTACATGGGTTATCAATTTCGC
GCCCATCGGCATCATGGGGCTTGTTTTCGATGCCATTGTCACTAACGGGCTTTCCGCTTTGATTGATTATGGAAAATTAT
TAGCAGTTCTTCTTGGGACGATGTGTTTTGTGGCATTCGTTATGAATCCACTCATTGTCTTTCTTAACATTCGGCAAAAT
CCGTATCCGCTCGTTTGGAGATGCATTCGGGAAAGCGGGGTTACAGCGTTCTTTACACGCAGCTCGGCCGCAAACATTCC
TGTAAACTTGCGGTTATCCGAAATGCTTGGGCTCAATAAAAATACGTATTCTATTTCGATCCCACTCGGCGCAACGATTA
ATATGGCTGGCGCCGCTGTGACGATTTCCGTCTTAACGCTCGCTGCGGTTCATACGTTGGAAATTGAAGTTGACCTAGGC
ACTGCACTCATTCTTAGCGTTCTTTCTGCCATCGCCGCCGCGGGGGCATCCGGTGTCGCTGGGGGGTCGCTCCTCCTTAT
CCCATTAGCATGCAGTTTGTTTGGCATCCCGAATGATATCGCCATGCAAGTCGTAGGGGTCGGTTTCATCATTGGCGTTT
TGCAAGATTCATGCGAAACTGCCCTAAACTCATCCTCGGATGTCCTTTTTACCGCCACAGCAGAATATGCGAAAAGACGC
AAAGAAGGAAAACAAGTGGCCATCAAAGCATAA

Upstream 100 bases:

>100_bases
CATGTTAAACTAATGAGTGTTCACCTACAGAAAACATTTGTATACGTACAGTGGAATTTATTCTCATACGCTCATCATGA
ATGATCAGGAGGAACGTGTT

Downstream 100 bases:

>100_bases
CGGCATCCCCCTTTGCATGGTGTCTGAAAAGCGAAAGCAGGGCCATTCAAACTGTCCCGACCGGGGCCAGCCATGAAAAC
GAGATTTACGAACGTTTCGG

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKQLIAKWNRVSLVKRIIIGIIIGITLAVTVPESTKWISIFGSLFVGALKAVAPVLVFFLVISAISRHQSGQKTNIQHIL
ILYGFSTFLASLTAVVASFLFPVHLSLTESAKEVSPPSNITEVIQSLLFNIVDNPVHALLNANYIGILTWAVLLGIALRT
APETTKNVIAHFSDAISQIVTWVINFAPIGIMGLVFDAIVTNGLSALIDYGKLLAVLLGTMCFVAFVMNPLIVFLNIRQN
PYPLVWRCIRESGVTAFFTRSSAANIPVNLRLSEMLGLNKNTYSISIPLGATINMAGAAVTISVLTLAAVHTLEIEVDLG
TALILSVLSAIAAAGASGVAGGSLLLIPLACSLFGIPNDIAMQVVGVGFIIGVLQDSCETALNSSSDVLFTATAEYAKRR
KEGKQVAIKA

Sequences:

>Translated_410_residues
MKQLIAKWNRVSLVKRIIIGIIIGITLAVTVPESTKWISIFGSLFVGALKAVAPVLVFFLVISAISRHQSGQKTNIQHIL
ILYGFSTFLASLTAVVASFLFPVHLSLTESAKEVSPPSNITEVIQSLLFNIVDNPVHALLNANYIGILTWAVLLGIALRT
APETTKNVIAHFSDAISQIVTWVINFAPIGIMGLVFDAIVTNGLSALIDYGKLLAVLLGTMCFVAFVMNPLIVFLNIRQN
PYPLVWRCIRESGVTAFFTRSSAANIPVNLRLSEMLGLNKNTYSISIPLGATINMAGAAVTISVLTLAAVHTLEIEVDLG
TALILSVLSAIAAAGASGVAGGSLLLIPLACSLFGIPNDIAMQVVGVGFIIGVLQDSCETALNSSSDVLFTATAEYAKRR
KEGKQVAIKA
>Mature_410_residues
MKQLIAKWNRVSLVKRIIIGIIIGITLAVTVPESTKWISIFGSLFVGALKAVAPVLVFFLVISAISRHQSGQKTNIQHIL
ILYGFSTFLASLTAVVASFLFPVHLSLTESAKEVSPPSNITEVIQSLLFNIVDNPVHALLNANYIGILTWAVLLGIALRT
APETTKNVIAHFSDAISQIVTWVINFAPIGIMGLVFDAIVTNGLSALIDYGKLLAVLLGTMCFVAFVMNPLIVFLNIRQN
PYPLVWRCIRESGVTAFFTRSSAANIPVNLRLSEMLGLNKNTYSISIPLGATINMAGAAVTISVLTLAAVHTLEIEVDLG
TALILSVLSAIAAAGASGVAGGSLLLIPLACSLFGIPNDIAMQVVGVGFIIGVLQDSCETALNSSSDVLFTATAEYAKRR
KEGKQVAIKA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI223468564, Length=269, Percent_Identity=29.7397769516729, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI223468566, Length=269, Percent_Identity=29.7397769516729, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI21314632, Length=272, Percent_Identity=27.9411764705882, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI5032093, Length=269, Percent_Identity=29.7397769516729, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4827012, Length=267, Percent_Identity=25.4681647940075, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI169790839, Length=295, Percent_Identity=25.0847457627119, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI66773030, Length=273, Percent_Identity=24.5421245421245, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI40254478, Length=253, Percent_Identity=25.296442687747, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789473, Length=390, Percent_Identity=62.3076923076923, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1789947, Length=379, Percent_Identity=23.2189973614776, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790514, Length=310, Percent_Identity=23.8709677419355, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193206505, Length=438, Percent_Identity=24.6575342465753, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17537407, Length=418, Percent_Identity=23.9234449760766, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71983099, Length=256, Percent_Identity=25.390625, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71983106, Length=256, Percent_Identity=25.390625, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71996953, Length=264, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583025, Length=423, Percent_Identity=24.5862884160757, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17137668, Length=423, Percent_Identity=24.5862884160757, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24583023, Length=423, Percent_Identity=24.5862884160757, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_GEOTN (A4IK45)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001124444.1
- ProteinModelPortal:   A4IK45
- SMR:   A4IK45
- STRING:   A4IK45
- GeneID:   4965261
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_0317
- NMPDR:   fig|420246.5.peg.304
- eggNOG:   COG3633
- HOGENOM:   HBG289387
- OMA:   ETTHIRP
- PhylomeDB:   A4IK45
- ProtClustDB:   PRK13628
- BioCyc:   GTHE420246:GTNG_0317-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 43582; Mature: 43582

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xc04a1c0)-; HASH(0xc5ad520)-; HASH(0xcc819f0)-; HASH(0xc789d3c)-; HASH(0xc9d06e0)-; HASH(0xc0b096c)-; HASH(0xc23cef8)-; HASH(0xab3d648)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLIAKWNRVSLVKRIIIGIIIGITLAVTVPESTKWISIFGSLFVGALKAVAPVLVFFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VISAISRHQSGQKTNIQHILILYGFSTFLASLTAVVASFLFPVHLSLTESAKEVSPPSNI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TEVIQSLLFNIVDNPVHALLNANYIGILTWAVLLGIALRTAPETTKNVIAHFSDAISQIV
HHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TWVINFAPIGIMGLVFDAIVTNGLSALIDYGKLLAVLLGTMCFVAFVMNPLIVFLNIRQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
PYPLVWRCIRESGVTAFFTRSSAANIPVNLRLSEMLGLNKNTYSISIPLGATINMAGAAV
CHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHCCCCCCEEEEECCCCEEECCHHHH
TISVLTLAAVHTLEIEVDLGTALILSVLSAIAAAGASGVAGGSLLLIPLACSLFGIPNDI
HHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHH
AMQVVGVGFIIGVLQDSCETALNSSSDVLFTATAEYAKRRKEGKQVAIKA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCEEEECH
>Mature Secondary Structure
MKQLIAKWNRVSLVKRIIIGIIIGITLAVTVPESTKWISIFGSLFVGALKAVAPVLVFFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VISAISRHQSGQKTNIQHILILYGFSTFLASLTAVVASFLFPVHLSLTESAKEVSPPSNI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TEVIQSLLFNIVDNPVHALLNANYIGILTWAVLLGIALRTAPETTKNVIAHFSDAISQIV
HHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TWVINFAPIGIMGLVFDAIVTNGLSALIDYGKLLAVLLGTMCFVAFVMNPLIVFLNIRQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
PYPLVWRCIRESGVTAFFTRSSAANIPVNLRLSEMLGLNKNTYSISIPLGATINMAGAAV
CHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHCCCCCCEEEEECCCCEEECCHHHH
TISVLTLAAVHTLEIEVDLGTALILSVLSAIAAAGASGVAGGSLLLIPLACSLFGIPNDI
HHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHH
AMQVVGVGFIIGVLQDSCETALNSSSDVLFTATAEYAKRRKEGKQVAIKA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA