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The map label for this gene is dat [H]

Identifier: 13475032

GI number: 13475032

Start: 4868238

End: 4869527

Strand: Direct

Name: dat [H]

Synonym: mlr6024

Alternate gene names: 13475032

Gene position: 4868238-4869527 (Clockwise)

Preceding gene: 13475031

Following gene: 13475033

Centisome position: 69.19

GC content: 57.21

Gene sequence:

>1290_bases
ATGAGCGATCTGCCTGAACGACTCCACGACATTATCCGACGCCGGAATATGGTGCTCGGGCCGGGTTACCAGTTTTCCGA
GACTATTCCGGTGGAGTTTGTCTCGAGTTTTGGTGCCCACCTGATAGACAGCGACGGCAATGACTATCTCGACGCGTTTA
ACAACGTGCAGGGCGTCGGCCACGCGCACAGGCATGTAGCGGACGCGGTCGCCCGCCAGATTGCAGCGATCAACACAGAT
ACACGCTACCCCCAGGAAGCGCTGGTGGCCTATGCCGAGCGGCTACTTGCAACATTCCCAGCCGAACTTTCGAAACTAAG
CTTGCCCTGCACTGGATCTGAAGCAAATGATCTCGCAGTTCGGGTCGCGAGGTACCATACGGGCGGCGAAGGTATCATAG
TTACGCGCTGGGCGTTTCACGGTCGCACTCGTGAGGTCGCCAGTTTTTCCCCAATGCTGGGCGCAGGATCCCCGCTGGGA
CCAAACGTCCGGCTTATTGCCGCTCCTGACCCCAGGTTCTGCGGACCCCAACAATCCCTTGAGAATTATATGCGGGATCA
AGTGCGTTCCGCAATTGTTGATCTCGAACGGCACGGATACAGGCTAGCAGCCTTAGTCGCCGATTCCGCGTTCACCTCAG
ACGGCATTTTTACTCACCCTGTGGGCTTCCTGCAGGCCATGGTCGACGAAGTTCATGCCGCTGGTGGCCTTCACATCGCT
GACGAGGTTCAATCAGGGTTCGCTCAGCTCGGAGATTCGATGTGGGGGTTCAGTCGGCACGGGGTAGTTCCAGATATCGT
CACGATGGGCAAGGCGATTGGGAATGGTTTCCCCATCTCTGGCGTCGTCTTCCGCCCGGAGGTATCTGACGAATTCGGAC
AGAAGGTTAGCTATTTCAATACATTGGGCGGCCGATCGCTTTCTATAGCCGCGGCGTCCGCAGTGCTCGATGTGTTCGAG
CAGGAGAATGTGCGTGAACGCGTTGCCGTGAACGGAGCGGCCTTGCAGTCAGGGCTTGAAACGCTGGCGCGGGAGTCTCC
TTACGTTGCGGAGATCCGAGGTAGCGGGCTATACCTTGGTGTCGAGATCGTGAAGGACAGAGAGACACTTGAGCCCGATC
CCATTCGTTGCGAAAGCATCATCAAGGACCTTCGCGATCGTCGAGTTCTTATCAGCCGGACCGGCTCCTCGGGTAACGTG
TTGAAAGTTCGTCCTCCAGTCGCTTTCACCGCTGCCGATGTGTCTCGATTCCTTGAGACCTTTGCCATCGTAGCGAAACA
GCGGCTCTAG

Upstream 100 bases:

>100_bases
CTAGCAGCGGACCGTGCGAAAACCCCGGTGGGTTTTTTCAATCGTTCGCTGTCAAGCTAAGATGAGCGCGCGGCAACCCA
CGCGGATCGATGCGAATGAT

Downstream 100 bases:

>100_bases
AAGGCTCTAGCAACATGAACAAAATACCTGACGCAATACTGCAACGGCTCCTGGAGGAGAGCAGCCTGCTCTCATCAAGC
GAATCTATCGACCCCTTGTT

Product: putative aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSDLPERLHDIIRRRNMVLGPGYQFSETIPVEFVSSFGAHLIDSDGNDYLDAFNNVQGVGHAHRHVADAVARQIAAINTD
TRYPQEALVAYAERLLATFPAELSKLSLPCTGSEANDLAVRVARYHTGGEGIIVTRWAFHGRTREVASFSPMLGAGSPLG
PNVRLIAAPDPRFCGPQQSLENYMRDQVRSAIVDLERHGYRLAALVADSAFTSDGIFTHPVGFLQAMVDEVHAAGGLHIA
DEVQSGFAQLGDSMWGFSRHGVVPDIVTMGKAIGNGFPISGVVFRPEVSDEFGQKVSYFNTLGGRSLSIAAASAVLDVFE
QENVRERVAVNGAALQSGLETLARESPYVAEIRGSGLYLGVEIVKDRETLEPDPIRCESIIKDLRDRRVLISRTGSSGNV
LKVRPPVAFTAADVSRFLETFAIVAKQRL

Sequences:

>Translated_429_residues
MSDLPERLHDIIRRRNMVLGPGYQFSETIPVEFVSSFGAHLIDSDGNDYLDAFNNVQGVGHAHRHVADAVARQIAAINTD
TRYPQEALVAYAERLLATFPAELSKLSLPCTGSEANDLAVRVARYHTGGEGIIVTRWAFHGRTREVASFSPMLGAGSPLG
PNVRLIAAPDPRFCGPQQSLENYMRDQVRSAIVDLERHGYRLAALVADSAFTSDGIFTHPVGFLQAMVDEVHAAGGLHIA
DEVQSGFAQLGDSMWGFSRHGVVPDIVTMGKAIGNGFPISGVVFRPEVSDEFGQKVSYFNTLGGRSLSIAAASAVLDVFE
QENVRERVAVNGAALQSGLETLARESPYVAEIRGSGLYLGVEIVKDRETLEPDPIRCESIIKDLRDRRVLISRTGSSGNV
LKVRPPVAFTAADVSRFLETFAIVAKQRL
>Mature_428_residues
SDLPERLHDIIRRRNMVLGPGYQFSETIPVEFVSSFGAHLIDSDGNDYLDAFNNVQGVGHAHRHVADAVARQIAAINTDT
RYPQEALVAYAERLLATFPAELSKLSLPCTGSEANDLAVRVARYHTGGEGIIVTRWAFHGRTREVASFSPMLGAGSPLGP
NVRLIAAPDPRFCGPQQSLENYMRDQVRSAIVDLERHGYRLAALVADSAFTSDGIFTHPVGFLQAMVDEVHAAGGLHIAD
EVQSGFAQLGDSMWGFSRHGVVPDIVTMGKAIGNGFPISGVVFRPEVSDEFGQKVSYFNTLGGRSLSIAAASAVLDVFEQ
ENVRERVAVNGAALQSGLETLARESPYVAEIRGSGLYLGVEIVKDRETLEPDPIRCESIIKDLRDRRVLISRTGSSGNVL
KVRPPVAFTAADVSRFLETFAIVAKQRL

Specific function: 4-aminobutyrate (GABA) degradation. [C]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=418, Percent_Identity=35.4066985645933, Blast_Score=261, Evalue=8e-70,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=34.9282296650718, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI226442709, Length=368, Percent_Identity=35.8695652173913, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI24119277, Length=391, Percent_Identity=34.5268542199489, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI13994255, Length=422, Percent_Identity=30.3317535545024, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4557809, Length=411, Percent_Identity=26.0340632603406, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI284507298, Length=321, Percent_Identity=26.4797507788162, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789016, Length=388, Percent_Identity=28.6082474226804, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI145693181, Length=382, Percent_Identity=27.4869109947644, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787560, Length=384, Percent_Identity=30.2083333333333, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789759, Length=416, Percent_Identity=24.5192307692308, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788044, Length=420, Percent_Identity=25.2380952380952, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786349, Length=322, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71992977, Length=430, Percent_Identity=34.1860465116279, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI32564660, Length=416, Percent_Identity=33.8942307692308, Blast_Score=218, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI25144271, Length=424, Percent_Identity=26.4150943396226, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71992985, Length=132, Percent_Identity=34.8484848484849, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25144274, Length=233, Percent_Identity=27.4678111587983, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=371, Percent_Identity=25.8760107816712, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323470, Length=418, Percent_Identity=25.5980861244019, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356575, Length=437, Percent_Identity=34.5537757437071, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI161085790, Length=440, Percent_Identity=34.3181818181818, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI28574759, Length=448, Percent_Identity=33.2589285714286, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI21357415, Length=417, Percent_Identity=24.9400479616307, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46585; Mature: 46454

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPERLHDIIRRRNMVLGPGYQFSETIPVEFVSSFGAHLIDSDGNDYLDAFNNVQGVG
CCCHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHCCCCEECCCCCHHHHHHHCCCCCC
HAHRHVADAVARQIAAINTDTRYPQEALVAYAERLLATFPAELSKLSLPCTGSEANDLAV
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHEE
RVARYHTGGEGIIVTRWAFHGRTREVASFSPMLGAGSPLGPNVRLIAAPDPRFCGPQQSL
EEEEEEECCCEEEEEEEEECCCCCHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHH
ENYMRDQVRSAIVDLERHGYRLAALVADSAFTSDGIFTHPVGFLQAMVDEVHAAGGLHIA
HHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEECHHHHHHHHHHHHHHCCCCCHH
DEVQSGFAQLGDSMWGFSRHGVVPDIVTMGKAIGNGFPISGVVFRPEVSDEFGQKVSYFN
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHH
TLGGRSLSIAAASAVLDVFEQENVRERVAVNGAALQSGLETLARESPYVAEIRGSGLYLG
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEE
VEIVKDRETLEPDPIRCESIIKDLRDRRVLISRTGSSGNVLKVRPPVAFTAADVSRFLET
EEEEECCCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCEEEECCCCEEHHHHHHHHHHH
FAIVAKQRL
HHHHHHHCC
>Mature Secondary Structure 
SDLPERLHDIIRRRNMVLGPGYQFSETIPVEFVSSFGAHLIDSDGNDYLDAFNNVQGVG
CCHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHCCCCEECCCCCHHHHHHHCCCCCC
HAHRHVADAVARQIAAINTDTRYPQEALVAYAERLLATFPAELSKLSLPCTGSEANDLAV
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHEE
RVARYHTGGEGIIVTRWAFHGRTREVASFSPMLGAGSPLGPNVRLIAAPDPRFCGPQQSL
EEEEEEECCCEEEEEEEEECCCCCHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHH
ENYMRDQVRSAIVDLERHGYRLAALVADSAFTSDGIFTHPVGFLQAMVDEVHAAGGLHIA
HHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEECHHHHHHHHHHHHHHCCCCCHH
DEVQSGFAQLGDSMWGFSRHGVVPDIVTMGKAIGNGFPISGVVFRPEVSDEFGQKVSYFN
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHH
TLGGRSLSIAAASAVLDVFEQENVRERVAVNGAALQSGLETLARESPYVAEIRGSGLYLG
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEE
VEIVKDRETLEPDPIRCESIIKDLRDRRVLISRTGSSGNVLKVRPPVAFTAADVSRFLET
EEEEECCCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCEEEECCCCEEHHHHHHHHHHH
FAIVAKQRL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]