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The map label for this gene is kamA [H]

Identifier: 13474986

GI number: 13474986

Start: 4832441

End: 4833724

Strand: Direct

Name: kamA [H]

Synonym: mlr5971

Alternate gene names: 13474986

Gene position: 4832441-4833724 (Clockwise)

Preceding gene: 13474983

Following gene: 13474987

Centisome position: 68.68

GC content: 52.34

Gene sequence:

>1284_bases
ATGAGCCGCATCGCGCATGAGACGATGAGACACGAGTTCGCTGACGCTGCATGGCAAGATCATCATGCCGTTACTCGCGT
TGACCAGTTACGCGAATGGATGGGGGCCGACGCCGACGGCAACCTGATCCGTGACGTTGAGCGCGGGCTAGCGCGTGCGC
CAATGGCATTGCGTATCACGCCTTATCTGCTGAACTTGATTGACTGGTCGAACTTCCTCGAAGACCCAATTCGCAAGCAA
TTTATTCCCGTTGGAAGCGAACTTCTTCCCTCTCACCCGTTACTGAAAATGGACTCGTTGCATGAACGAAAAAGTTCACC
TGTAGATGGACTGGTGCACCGCTATAAGGACAAAGTACTTTTACTCGCAACGGATCGTTGCCCCGTCTATTGTCGTTTCT
GCACCCGCAGTTACAGCGTGGGCCTAGACACGCAATCGGTGTTGAAGAAAAAAGTGTCGCCATTTCAGAGTCGATGGGAC
ACTATATTGGCATATCTTCGCGTGACCCCCGTCATCGCCGATGTTGTGGTGTCGGGAGGAGATTGCTTTCGCCTCAAACC
TTCCCGACTATTGGCAATAGGCATGGGCCTTCTGTCTATTCCATCAATTCGCCGCATCCGATTCGCGACGAAAGGCCTCG
CTGTACTGCCTATGAAAATCACAAGCGATCATAAATGGACCGATGCTCTTGTTAACATTAGCGATGCTGGCCGGGATCAG
GGCGTAGAGATTTCATTTCACACCCACTTCAACCATCCTAGAGAAATCACCGATTACACGATTGCGGCTGCAGAGCTTCT
CTTCAAGCGGGGAATAAGGATGCGCAATCAGTCGGTTCTGATGGCTGGCGTCAATGACGATCCTGAGGTTATGAAACAGC
TCGTAAAAAAACTCTCAGACCTTCATATCCAGCCGTACTACGTGTACACTTGTGATCTTGTCGACGGAATCGAGCATATG
CGGTGCTCGGTAAGGCTAGCATGTCAGATAGAAAAGGCTGTACGCGGGATCACAGCTGGGTACAACACTCCGTTGTTCGT
TGTCGACACTCCGGGAGGCGGTGGAAAGCGTGACGTCCACAGCTTCGAGCATTATAATACACAAACAGGGCTTGCTGTGT
ACCGGGCTCTATCTGTCCGACCGGACCAGCTATTCACATATCCGGATCCTTTGCAGTCTCTCTCTCCAGATGCGCAGGCA
GCATGGGTCGATCCCTGGCGCGCCAAAGGCATGCTGAGGGAGGCGGTTAGGGCCGCTCGAGTAAAATTGATGGGGTTGGA
ATGA

Upstream 100 bases:

>100_bases
CCGCCGTGAAGTCGGAGGTCCTCGCGAAAAGCTGCCGATTGAGTGCGGCGCCATCGACGAGGTCATCATCTTTCCACTTT
TCAGCTCGAGCGAAGTTCTG

Downstream 100 bases:

>100_bases
GCGACTCGCCGGAATGCGTAGAGCTATGGCGGAAATTTGTGATGAGGATTTGAAGAGAGCGGCGTACCAAAGCGGGCGCG
GCAAAGCCTAGCAAAACTTA

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSRIAHETMRHEFADAAWQDHHAVTRVDQLREWMGADADGNLIRDVERGLARAPMALRITPYLLNLIDWSNFLEDPIRKQ
FIPVGSELLPSHPLLKMDSLHERKSSPVDGLVHRYKDKVLLLATDRCPVYCRFCTRSYSVGLDTQSVLKKKVSPFQSRWD
TILAYLRVTPVIADVVVSGGDCFRLKPSRLLAIGMGLLSIPSIRRIRFATKGLAVLPMKITSDHKWTDALVNISDAGRDQ
GVEISFHTHFNHPREITDYTIAAAELLFKRGIRMRNQSVLMAGVNDDPEVMKQLVKKLSDLHIQPYYVYTCDLVDGIEHM
RCSVRLACQIEKAVRGITAGYNTPLFVVDTPGGGGKRDVHSFEHYNTQTGLAVYRALSVRPDQLFTYPDPLQSLSPDAQA
AWVDPWRAKGMLREAVRAARVKLMGLE

Sequences:

>Translated_427_residues
MSRIAHETMRHEFADAAWQDHHAVTRVDQLREWMGADADGNLIRDVERGLARAPMALRITPYLLNLIDWSNFLEDPIRKQ
FIPVGSELLPSHPLLKMDSLHERKSSPVDGLVHRYKDKVLLLATDRCPVYCRFCTRSYSVGLDTQSVLKKKVSPFQSRWD
TILAYLRVTPVIADVVVSGGDCFRLKPSRLLAIGMGLLSIPSIRRIRFATKGLAVLPMKITSDHKWTDALVNISDAGRDQ
GVEISFHTHFNHPREITDYTIAAAELLFKRGIRMRNQSVLMAGVNDDPEVMKQLVKKLSDLHIQPYYVYTCDLVDGIEHM
RCSVRLACQIEKAVRGITAGYNTPLFVVDTPGGGGKRDVHSFEHYNTQTGLAVYRALSVRPDQLFTYPDPLQSLSPDAQA
AWVDPWRAKGMLREAVRAARVKLMGLE
>Mature_426_residues
SRIAHETMRHEFADAAWQDHHAVTRVDQLREWMGADADGNLIRDVERGLARAPMALRITPYLLNLIDWSNFLEDPIRKQF
IPVGSELLPSHPLLKMDSLHERKSSPVDGLVHRYKDKVLLLATDRCPVYCRFCTRSYSVGLDTQSVLKKKVSPFQSRWDT
ILAYLRVTPVIADVVVSGGDCFRLKPSRLLAIGMGLLSIPSIRRIRFATKGLAVLPMKITSDHKWTDALVNISDAGRDQG
VEISFHTHFNHPREITDYTIAAAELLFKRGIRMRNQSVLMAGVNDDPEVMKQLVKKLSDLHIQPYYVYTCDLVDGIEHMR
CSVRLACQIEKAVRGITAGYNTPLFVVDTPGGGGKRDVHSFEHYNTQTGLAVYRALSVRPDQLFTYPDPLQSLSPDAQAA
WVDPWRAKGMLREAVRAARVKLMGLE

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=333, Percent_Identity=28.5285285285285, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 48225; Mature: 48094

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIAHETMRHEFADAAWQDHHAVTRVDQLREWMGADADGNLIRDVERGLARAPMALRIT
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEH
PYLLNLIDWSNFLEDPIRKQFIPVGSELLPSHPLLKMDSLHERKSSPVDGLVHRYKDKVL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCEE
LLATDRCPVYCRFCTRSYSVGLDTQSVLKKKVSPFQSRWDTILAYLRVTPVIADVVVSGG
EEEECCCCEEEEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DCFRLKPSRLLAIGMGLLSIPSIRRIRFATKGLAVLPMKITSDHKWTDALVNISDAGRDQ
CEEEECHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCCHHHHEEECCCCCCCC
GVEISFHTHFNHPREITDYTIAAAELLFKRGIRMRNQSVLMAGVNDDPEVMKQLVKKLSD
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
LHIQPYYVYTCDLVDGIEHMRCSVRLACQIEKAVRGITAGYNTPLFVVDTPGGGGKRDVH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCH
SFEHYNTQTGLAVYRALSVRPDQLFTYPDPLQSLSPDAQAAWVDPWRAKGMLREAVRAAR
HHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEECCCHHHHHHHHHHHHHHH
VKLMGLE
HHEECCC
>Mature Secondary Structure 
SRIAHETMRHEFADAAWQDHHAVTRVDQLREWMGADADGNLIRDVERGLARAPMALRIT
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEH
PYLLNLIDWSNFLEDPIRKQFIPVGSELLPSHPLLKMDSLHERKSSPVDGLVHRYKDKVL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCEE
LLATDRCPVYCRFCTRSYSVGLDTQSVLKKKVSPFQSRWDTILAYLRVTPVIADVVVSGG
EEEECCCCEEEEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DCFRLKPSRLLAIGMGLLSIPSIRRIRFATKGLAVLPMKITSDHKWTDALVNISDAGRDQ
CEEEECHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCCHHHHEEECCCCCCCC
GVEISFHTHFNHPREITDYTIAAAELLFKRGIRMRNQSVLMAGVNDDPEVMKQLVKKLSD
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
LHIQPYYVYTCDLVDGIEHMRCSVRLACQIEKAVRGITAGYNTPLFVVDTPGGGGKRDVH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCH
SFEHYNTQTGLAVYRALSVRPDQLFTYPDPLQSLSPDAQAAWVDPWRAKGMLREAVRAAR
HHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEECCCHHHHHHHHHHHHHHH
VKLMGLE
HHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]