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The map label for this gene is rmlA2 [C]

Identifier: 13474901

GI number: 13474901

Start: 4753635

End: 4754453

Strand: Direct

Name: rmlA2 [C]

Synonym: mlr5884

Alternate gene names: 13474901

Gene position: 4753635-4754453 (Clockwise)

Preceding gene: 13474900

Following gene: 13474902

Centisome position: 67.56

GC content: 60.32

Gene sequence:

>819_bases
ATGCCTCCCGCTGCTCCCAGGAAAGCCGTCATTCTCGCCGCCGGCTTCGGCTCCCGCCTGCGTCCGCTGACCGATCTGTG
TCCCAAGCCCCTCGTCGAAGTCAACGGCACACCGATACTTTACAATGCACTGTGGAACCTTCAGACGGTGGGAGTTGAAG
AGGTGACGATTGTTGTCGGCTATCGCAAGGATGCCATTCGCCATGCCTGTGGCGAACGCTTCGGTAGACTTGAAATCAAC
TATGTCGAGTCCTCGGTCTTCGACAAGACAGGGAGCGCCTACTCGCTCTGGCTGGCACGCGACACGCTTCTTTCCGGCGA
CTGTTATCTCCTCGAAGGTGACGTCTTCTTCGAAGAAGATGCGCTGCGCCACCTGATCAGGGTGGAGGCGGCCAATGCCG
CCGCGGTCGCGCCCTTCGATCCATCCATGGAAGGGTCCGCGGTCGTCCTTTCCAGCAACGGCTTCATATCCGAAGTCCGG
TTGAAGCAGACGGCGGCAAATCTGGTATCAGGCACCCCGGTGCTCTTCAAGATGATGAACCTCATCCGGTTCTCTGGCGC
CGAACTCCAAACGGCGATCGTCCCGGTCCTCCACGACCTGATCGGCTCGGGCGCAATCAAAGCCTATACCGAGGAGCTAC
TCGCGCATCTCATCGAGCAGCGCGGACTGCAACTCGCCGCGGCGCGATGTGACGATTTGCGATGGTACGAGATCGACAGT
GAACAGGACCTGCGGGTAGCGGAAAGGATTTTCGCCTTCGAGCGACCTCACAGACATAGTGCCGACGCGCCGGCCGCCGT
GGCGGGGGTAGGAGGATGA

Upstream 100 bases:

>100_bases
TGGAATTCCATCTGAAAAACTCGCGACCGGCCTGGCCCGGCTCGTCGAATTCCTCAACTCCTGGAAATGACACCGCAACA
CAACGAAAGAGGTGAATGAG

Downstream 100 bases:

>100_bases
TCCGCTATCTGTTCGACGCTGCAAATGCCATTACGGCCCTTGGGCTGATCTTGGCCACCACGGCGATCTACTTTGCTTTG
ATCGGGCGCTTCGAGATTGG

Product: hemolysin erythrocyte lysis protein 2

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MPPAAPRKAVILAAGFGSRLRPLTDLCPKPLVEVNGTPILYNALWNLQTVGVEEVTIVVGYRKDAIRHACGERFGRLEIN
YVESSVFDKTGSAYSLWLARDTLLSGDCYLLEGDVFFEEDALRHLIRVEAANAAAVAPFDPSMEGSAVVLSSNGFISEVR
LKQTAANLVSGTPVLFKMMNLIRFSGAELQTAIVPVLHDLIGSGAIKAYTEELLAHLIEQRGLQLAAARCDDLRWYEIDS
EQDLRVAERIFAFERPHRHSADAPAAVAGVGG

Sequences:

>Translated_272_residues
MPPAAPRKAVILAAGFGSRLRPLTDLCPKPLVEVNGTPILYNALWNLQTVGVEEVTIVVGYRKDAIRHACGERFGRLEIN
YVESSVFDKTGSAYSLWLARDTLLSGDCYLLEGDVFFEEDALRHLIRVEAANAAAVAPFDPSMEGSAVVLSSNGFISEVR
LKQTAANLVSGTPVLFKMMNLIRFSGAELQTAIVPVLHDLIGSGAIKAYTEELLAHLIEQRGLQLAAARCDDLRWYEIDS
EQDLRVAERIFAFERPHRHSADAPAAVAGVGG
>Mature_271_residues
PPAAPRKAVILAAGFGSRLRPLTDLCPKPLVEVNGTPILYNALWNLQTVGVEEVTIVVGYRKDAIRHACGERFGRLEINY
VESSVFDKTGSAYSLWLARDTLLSGDCYLLEGDVFFEEDALRHLIRVEAANAAAVAPFDPSMEGSAVVLSSNGFISEVRL
KQTAANLVSGTPVLFKMMNLIRFSGAELQTAIVPVLHDLIGSGAIKAYTEELLAHLIEQRGLQLAAARCDDLRWYEIDSE
QDLRVAERIFAFERPHRHSADAPAAVAGVGG

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133931050, Length=212, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 29619; Mature: 29488

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAAPRKAVILAAGFGSRLRPLTDLCPKPLVEVNGTPILYNALWNLQTVGVEEVTIVVG
CCCCCCCCEEEEEECCCCCCCCHHHHCCCCCEECCCCEEEEEEHHCEEECCCEEEEEEEE
YRKDAIRHACGERFGRLEINYVESSVFDKTGSAYSLWLARDTLLSGDCYLLEGDVFFEED
CCHHHHHHHHHHHHCCEEEEEEHHHHHCCCCCEEEEEEEECCEECCCEEEEECCEEECHH
ALRHLIRVEAANAAAVAPFDPSMEGSAVVLSSNGFISEVRLKQTAANLVSGTPVLFKMMN
HHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHH
LIRFSGAELQTAIVPVLHDLIGSGAIKAYTEELLAHLIEQRGLQLAAARCDDLRWYEIDS
HHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECC
EQDLRVAERIFAFERPHRHSADAPAAVAGVGG
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPAAPRKAVILAAGFGSRLRPLTDLCPKPLVEVNGTPILYNALWNLQTVGVEEVTIVVG
CCCCCCCEEEEEECCCCCCCCHHHHCCCCCEECCCCEEEEEEHHCEEECCCEEEEEEEE
YRKDAIRHACGERFGRLEINYVESSVFDKTGSAYSLWLARDTLLSGDCYLLEGDVFFEED
CCHHHHHHHHHHHHCCEEEEEEHHHHHCCCCCEEEEEEEECCEECCCEEEEECCEEECHH
ALRHLIRVEAANAAAVAPFDPSMEGSAVVLSSNGFISEVRLKQTAANLVSGTPVLFKMMN
HHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHH
LIRFSGAELQTAIVPVLHDLIGSGAIKAYTEELLAHLIEQRGLQLAAARCDDLRWYEIDS
HHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECC
EQDLRVAERIFAFERPHRHSADAPAAVAGVGG
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA