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The map label for this gene is CYP127A1 [H]

Identifier: 13474893

GI number: 13474893

Start: 4745585

End: 4746802

Strand: Direct

Name: CYP127A1 [H]

Synonym: mlr5876

Alternate gene names: 13474893

Gene position: 4745585-4746802 (Clockwise)

Preceding gene: 13474892

Following gene: 13474894

Centisome position: 67.45

GC content: 60.02

Gene sequence:

>1218_bases
ATGGCGATCAACCCGGTCCCAGATCATGTCCCGCCCGAAATGGTGAGAGACTTCAGCCTGTTCACATCGCCAGGCATGCC
ACCAACGCCCAACGGGGATCCACACGCAGCCGTCGCTTGCGCCCATGACGGGCCTCCGATCTTCTATTCCCCCTACAACA
CGCAAGATGGCCGGGGCACCTGGGTCATCACCCGCGCCGCAGATCAGCGTAAGGTGCTGCAGGACACTGAAACTTTTTCC
AGCCATCGCAGCATCTTCTCCTCCATACTGGGCGAAACCTGGCCGACGATCCCGCTTGAGCTCGATCCACCGGCCCATGG
CGCATTTCGCTCACTGCTCAGTCCGCTGCTTTCGCCCAAGCGGGTGACGGCACTGGAACCGGCTGTCCGTGAGCGAGCGA
TAGCCCTGATCGACCGGATCACCGCATCGGCCACGAGCTGCGACGTCATGAAGGATTTTGCCTTTCCGTTCACTGTCAGC
ATCTTCCTTCGGTTTCTGGGGTTGCCGGATCAGGGACTCGATACATTTGTCGGCTGGGCGAAAGATCTGCTCCACGGCGA
CGATGTGGAACGACCTGTGGCTGCCCGCAAGATTGTGGCTTTCATCGATGAACTTGCAACCAATCGCCGCAAGGATCCGG
TCGACGATCTCATGACCTTCATCGTGCAGGCACAGATCGAGGGCCGCCGGCTAACCGACGGGGAGATCCGTGGCATCGGC
GTGCTTGTGTTCGTCGCGGGACTTGACACTGTCGCAGCAGCTATTGGCTTTGACCTGGCTTATCTAGCGCGCAACCTCAA
GGATCAGGAACTGCTGCGCAGCGAACCGGCCCGCATCCTGCTCGCAACCGAAGAGTTGCTGCGGGCCTATCCGCCCATTC
AGTTGATCCGCGTGGCTACGAAAGATATCGACTTCGAAGGCGCGCCGATCCGAAAGGGGGACTATGTTTCGTGCGCCACG
ATGATTGCAAATCGCGACCCGGAGGAATTCGAATCCCCCAACACGGTCGATCTGGCGCGAGATCACAACCGCCACGCCGC
CTTTGGCTATGGTCCCCACCGTTGCCTTGGCTCACACCTTGCCCGGCGCGAGATTGTCATTGGCCTGGAGGAATGGCTGG
CGCGCATACCGACCTTCCGGATCAAGGAGGGTACAGCGCCCATCACCTGTGGCGGCCATGTGTTCGGGATCGAAAATCTG
ATCCTGGACTGGTCATGA

Upstream 100 bases:

>100_bases
AAAACGCCGGGTCTCCGACGATTTCGCTCGTCGGCTCTCTAGATGACCAAGATGCCATGGTGCGCGGCCTGGTTAGTGGT
TAGACGGCAGGAGAAATGCA

Downstream 100 bases:

>100_bases
CCATCGCCGAGCCATGCCAAGACAATGGAGGCAGCGCTATGCGCATTATCGTCCACAATGCCAAATGCCAGGGTCACGCG
CGATGCTGGGCGCAAGCGCC

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAINPVPDHVPPEMVRDFSLFTSPGMPPTPNGDPHAAVACAHDGPPIFYSPYNTQDGRGTWVITRAADQRKVLQDTETFS
SHRSIFSSILGETWPTIPLELDPPAHGAFRSLLSPLLSPKRVTALEPAVRERAIALIDRITASATSCDVMKDFAFPFTVS
IFLRFLGLPDQGLDTFVGWAKDLLHGDDVERPVAARKIVAFIDELATNRRKDPVDDLMTFIVQAQIEGRRLTDGEIRGIG
VLVFVAGLDTVAAAIGFDLAYLARNLKDQELLRSEPARILLATEELLRAYPPIQLIRVATKDIDFEGAPIRKGDYVSCAT
MIANRDPEEFESPNTVDLARDHNRHAAFGYGPHRCLGSHLARREIVIGLEEWLARIPTFRIKEGTAPITCGGHVFGIENL
ILDWS

Sequences:

>Translated_405_residues
MAINPVPDHVPPEMVRDFSLFTSPGMPPTPNGDPHAAVACAHDGPPIFYSPYNTQDGRGTWVITRAADQRKVLQDTETFS
SHRSIFSSILGETWPTIPLELDPPAHGAFRSLLSPLLSPKRVTALEPAVRERAIALIDRITASATSCDVMKDFAFPFTVS
IFLRFLGLPDQGLDTFVGWAKDLLHGDDVERPVAARKIVAFIDELATNRRKDPVDDLMTFIVQAQIEGRRLTDGEIRGIG
VLVFVAGLDTVAAAIGFDLAYLARNLKDQELLRSEPARILLATEELLRAYPPIQLIRVATKDIDFEGAPIRKGDYVSCAT
MIANRDPEEFESPNTVDLARDHNRHAAFGYGPHRCLGSHLARREIVIGLEEWLARIPTFRIKEGTAPITCGGHVFGIENL
ILDWS
>Mature_404_residues
AINPVPDHVPPEMVRDFSLFTSPGMPPTPNGDPHAAVACAHDGPPIFYSPYNTQDGRGTWVITRAADQRKVLQDTETFSS
HRSIFSSILGETWPTIPLELDPPAHGAFRSLLSPLLSPKRVTALEPAVRERAIALIDRITASATSCDVMKDFAFPFTVSI
FLRFLGLPDQGLDTFVGWAKDLLHGDDVERPVAARKIVAFIDELATNRRKDPVDDLMTFIVQAQIEGRRLTDGEIRGIGV
LVFVAGLDTVAAAIGFDLAYLARNLKDQELLRSEPARILLATEELLRAYPPIQLIRVATKDIDFEGAPIRKGDYVSCATM
IANRDPEEFESPNTVDLARDHNRHAAFGYGPHRCLGSHLARREIVIGLEEWLARIPTFRIKEGTAPITCGGHVFGIENLI
LDWS

Specific function: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 44731; Mature: 44599

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINPVPDHVPPEMVRDFSLFTSPGMPPTPNGDPHAAVACAHDGPPIFYSPYNTQDGRGT
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCEE
WVITRAADQRKVLQDTETFSSHRSIFSSILGETWPTIPLELDPPAHGAFRSLLSPLLSPK
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCC
RVTALEPAVRERAIALIDRITASATSCDVMKDFAFPFTVSIFLRFLGLPDQGLDTFVGWA
HHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHH
KDLLHGDDVERPVAARKIVAFIDELATNRRKDPVDDLMTFIVQAQIEGRRLTDGEIRGIG
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEE
VLVFVAGLDTVAAAIGFDLAYLARNLKDQELLRSEPARILLATEELLRAYPPIQLIRVAT
EEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHH
KDIDFEGAPIRKGDYVSCATMIANRDPEEFESPNTVDLARDHNRHAAFGYGPHRCLGSHL
HCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCEEHHCCCCCCCCCCCCHHHHHHHHH
ARREIVIGLEEWLARIPTFRIKEGTAPITCGGHVFGIENLILDWS
HHHHHHCCHHHHHHHCCCEEEECCCCCEEECCEEEEHHHEEEECC
>Mature Secondary Structure 
AINPVPDHVPPEMVRDFSLFTSPGMPPTPNGDPHAAVACAHDGPPIFYSPYNTQDGRGT
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCEE
WVITRAADQRKVLQDTETFSSHRSIFSSILGETWPTIPLELDPPAHGAFRSLLSPLLSPK
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCC
RVTALEPAVRERAIALIDRITASATSCDVMKDFAFPFTVSIFLRFLGLPDQGLDTFVGWA
HHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHH
KDLLHGDDVERPVAARKIVAFIDELATNRRKDPVDDLMTFIVQAQIEGRRLTDGEIRGIG
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEE
VLVFVAGLDTVAAAIGFDLAYLARNLKDQELLRSEPARILLATEELLRAYPPIQLIRVAT
EEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHH
KDIDFEGAPIRKGDYVSCATMIANRDPEEFESPNTVDLARDHNRHAAFGYGPHRCLGSHL
HCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCEEHHCCCCCCCCCCCCHHHHHHHHH
ARREIVIGLEEWLARIPTFRIKEGTAPITCGGHVFGIENLILDWS
HHHHHHCCHHHHHHHCCCEEEECCCCCEEECCEEEEHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]