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The map label for this gene is soxB [H]

Identifier: 13474869

GI number: 13474869

Start: 4720304

End: 4721578

Strand: Direct

Name: soxB [H]

Synonym: mlr5845

Alternate gene names: 13474869

Gene position: 4720304-4721578 (Clockwise)

Preceding gene: 13474867

Following gene: 13474870

Centisome position: 67.09

GC content: 64.08

Gene sequence:

>1275_bases
ATGCGGCCTTTCAACTCGCTAGGCCCGCGCCCGCCGCGGCACGCGCTTCGACATCATGCTGACGGCTGTGTGATCGACAC
GGGCGGTTACCGGAAAGGCGACAAAAAAGTGCGTTACGACATCGTTATCATCGGAGGAGCCATCGTCGGCTCCTCGATCG
CCTACTATCTGCGCGAGGAAGGGTTTTCCGGCTCGATCGCGCTGATCGAGCGCGATCCGCAGTTCGCGCACGCGGCAACG
ACGTTGTCCTGCGCCTCCATTCGCCAGCAGTTTTCGATTCCTGAAAACATCCGCCTGTCGCAATTCGCGCTGAAGCTGTT
CCGGCGGCTGAAGGAAGAATTCGGCACGGATGCCGATATCGGGTTCCGCGAGAGCGGCTATCTGATCCTCGCCGGAGAAG
CCGGGCTACCGATCCTCAAGGCCAATCACGAGGCGCAGATCGCCGAGGGCGCCGACATCGTGCTCGAGGATGCCGAGCAG
TTGACGCAGCGCTTCGCCTGGCTGTCGACCGAAGGCATTTCTGCCGGCGCCTATGGTCGGACCGGCGAAGGCTGGTTCGA
CGCGCATGCGATGCTGACGCTGTTCCGCAAGGCGCTGCGCGGCAAGAACGTGGACTTTATGACCGCCTCGGTCATCGGCA
TCGAGCGGCAGGGCCACCGTGTCACCGGCGTCAGGCTCGACAATGGCGAGACGATCGAAGCCGGCACCGTCCTCAATGCC
GCCGGGCCGAATGCCGGCAAGGTCGCCGCTCTCGCCGGGCTGGCGCTGCCGGTCGAGCCGCGCAAGCGCAATGTCTTCGT
CTTCGAGGCGCGCGAAAAATATGCCGACATGCCGCTGCTGGTCGATCCCTCCGGCATCTATGTCAGGCCGGAAGGCCCGG
TCTATCTCACCGGCGGCGCCGAGCCGGAAGAGGGCGACGGCCCGGCCGATCCCCAGGATTTCGAGGTCGACTGGCCGCTG
TTCGAAGAGGTGATTTGGCCGGTGCTGGCGACCCGCATTCCAGCCTTCGAGGCCATCAAGCCTACCCGCGCCTGGGCCGG
GCACTACGATTACAACACGCTCGACCAGAACGCGGTGATCGGGCCGCACCCCAAGGTGAAAAATTTCCTCTTCGCCAACG
GATTTTCAGGCCACGGTCTGCAGCAGGCCCCGGCGGTCGGCAAGGCGCTGGCCGAGCTTCTCGTGCATGGCGGCTACCGC
ACGGTCGATTGCTCCGCGTTTGGGTACATCCGTGTCGCCGAAGGGCGGGCGTTTAGGGAATTGAATGTGATCTAG

Upstream 100 bases:

>100_bases
CGTGAAGAGCCTGAGTTCACCTGGGAGAAGACGGACAGAGCCGACGACTTGCTGCGTGAGGCAGGACCGGCAGCTGCGTG
AACGCCGCTGGATCAAGCGC

Downstream 100 bases:

>100_bases
CAACAATGGCGCCGCGACGGTCTCCTTTGGTGCCGGCGGGACAGAGGGGCGCGAAGGTTCGCGACAGGCGGTGCCGCGGT
ACAAAGGCCTTGATGTTTAG

Product: hypothetical protein

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRPFNSLGPRPPRHALRHHADGCVIDTGGYRKGDKKVRYDIVIIGGAIVGSSIAYYLREEGFSGSIALIERDPQFAHAAT
TLSCASIRQQFSIPENIRLSQFALKLFRRLKEEFGTDADIGFRESGYLILAGEAGLPILKANHEAQIAEGADIVLEDAEQ
LTQRFAWLSTEGISAGAYGRTGEGWFDAHAMLTLFRKALRGKNVDFMTASVIGIERQGHRVTGVRLDNGETIEAGTVLNA
AGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYADMPLLVDPSGIYVRPEGPVYLTGGAEPEEGDGPADPQDFEVDWPL
FEEVIWPVLATRIPAFEAIKPTRAWAGHYDYNTLDQNAVIGPHPKVKNFLFANGFSGHGLQQAPAVGKALAELLVHGGYR
TVDCSAFGYIRVAEGRAFRELNVI

Sequences:

>Translated_424_residues
MRPFNSLGPRPPRHALRHHADGCVIDTGGYRKGDKKVRYDIVIIGGAIVGSSIAYYLREEGFSGSIALIERDPQFAHAAT
TLSCASIRQQFSIPENIRLSQFALKLFRRLKEEFGTDADIGFRESGYLILAGEAGLPILKANHEAQIAEGADIVLEDAEQ
LTQRFAWLSTEGISAGAYGRTGEGWFDAHAMLTLFRKALRGKNVDFMTASVIGIERQGHRVTGVRLDNGETIEAGTVLNA
AGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYADMPLLVDPSGIYVRPEGPVYLTGGAEPEEGDGPADPQDFEVDWPL
FEEVIWPVLATRIPAFEAIKPTRAWAGHYDYNTLDQNAVIGPHPKVKNFLFANGFSGHGLQQAPAVGKALAELLVHGGYR
TVDCSAFGYIRVAEGRAFRELNVI
>Mature_424_residues
MRPFNSLGPRPPRHALRHHADGCVIDTGGYRKGDKKVRYDIVIIGGAIVGSSIAYYLREEGFSGSIALIERDPQFAHAAT
TLSCASIRQQFSIPENIRLSQFALKLFRRLKEEFGTDADIGFRESGYLILAGEAGLPILKANHEAQIAEGADIVLEDAEQ
LTQRFAWLSTEGISAGAYGRTGEGWFDAHAMLTLFRKALRGKNVDFMTASVIGIERQGHRVTGVRLDNGETIEAGTVLNA
AGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYADMPLLVDPSGIYVRPEGPVYLTGGAEPEEGDGPADPQDFEVDWPL
FEEVIWPVLATRIPAFEAIKPTRAWAGHYDYNTLDQNAVIGPHPKVKNFLFANGFSGHGLQQAPAVGKALAELLVHGGYR
TVDCSAFGYIRVAEGRAFRELNVI

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI8923708, Length=412, Percent_Identity=40.2912621359223, Blast_Score=285, Evalue=8e-77,
Organism=Homo sapiens, GI197927446, Length=374, Percent_Identity=25.1336898395722, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI21361378, Length=374, Percent_Identity=25.1336898395722, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI194306651, Length=372, Percent_Identity=24.7311827956989, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI60499001, Length=391, Percent_Identity=24.8081841432225, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17541536, Length=455, Percent_Identity=30.5494505494506, Blast_Score=207, Evalue=8e-54,
Organism=Drosophila melanogaster, GI20129729, Length=409, Percent_Identity=40.0977995110024, Blast_Score=275, Evalue=4e-74,
Organism=Drosophila melanogaster, GI17985989, Length=425, Percent_Identity=33.8823529411765, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI20130091, Length=391, Percent_Identity=24.8081841432225, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 46198; Mature: 46198

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPFNSLGPRPPRHALRHHADGCVIDTGGYRKGDKKVRYDIVIIGGAIVGSSIAYYLREE
CCCCCCCCCCCHHHHHHHCCCCEEECCCCCCCCCCEEEEEEEEEECHHHHHHHEEHHHHC
GFSGSIALIERDPQFAHAATTLSCASIRQQFSIPENIRLSQFALKLFRRLKEEFGTDADI
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GFRESGYLILAGEAGLPILKANHEAQIAEGADIVLEDAEQLTQRFAWLSTEGISAGAYGR
CCCCCCEEEEECCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCC
TGEGWFDAHAMLTLFRKALRGKNVDFMTASVIGIERQGHRVTGVRLDNGETIEAGTVLNA
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEEEECCCCEEECCEEEEC
AGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYADMPLLVDPSGIYVRPEGPVYLTGGA
CCCCCCCCHHHHCEECCCCCCCCCEEEEECCHHHCCCCEEECCCCEEECCCCCEEEECCC
EPEEGDGPADPQDFEVDWPLFEEVIWPVLATRIPAFEAIKPTRAWAGHYDYNTLDQNAVI
CCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCHHCCCCCHHHCCCCCCCCCCCCCEE
GPHPKVKNFLFANGFSGHGLQQAPAVGKALAELLVHGGYRTVDCSAFGYIRVAEGRAFRE
CCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCEEE
LNVI
ECCC
>Mature Secondary Structure
MRPFNSLGPRPPRHALRHHADGCVIDTGGYRKGDKKVRYDIVIIGGAIVGSSIAYYLREE
CCCCCCCCCCCHHHHHHHCCCCEEECCCCCCCCCCEEEEEEEEEECHHHHHHHEEHHHHC
GFSGSIALIERDPQFAHAATTLSCASIRQQFSIPENIRLSQFALKLFRRLKEEFGTDADI
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GFRESGYLILAGEAGLPILKANHEAQIAEGADIVLEDAEQLTQRFAWLSTEGISAGAYGR
CCCCCCEEEEECCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCC
TGEGWFDAHAMLTLFRKALRGKNVDFMTASVIGIERQGHRVTGVRLDNGETIEAGTVLNA
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEEEECCCCEEECCEEEEC
AGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYADMPLLVDPSGIYVRPEGPVYLTGGA
CCCCCCCCHHHHCEECCCCCCCCCEEEEECCHHHCCCCEEECCCCEEECCCCCEEEECCC
EPEEGDGPADPQDFEVDWPLFEEVIWPVLATRIPAFEAIKPTRAWAGHYDYNTLDQNAVI
CCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCHHCCCCCHHHCCCCCCCCCCCCCEE
GPHPKVKNFLFANGFSGHGLQQAPAVGKALAELLVHGGYRTVDCSAFGYIRVAEGRAFRE
CCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCEEE
LNVI
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]