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The map label for this gene is xanB [H]

Identifier: 13474830

GI number: 13474830

Start: 4679029

End: 4680444

Strand: Direct

Name: xanB [H]

Synonym: mlr5802

Alternate gene names: 13474830

Gene position: 4679029-4680444 (Clockwise)

Preceding gene: 13474829

Following gene: 13474833

Centisome position: 66.5

GC content: 58.26

Gene sequence:

>1416_bases
ATGAAAGTGGTTCCGGTCATCATCAGCGGTGGAGCTGGTTCGCGGCTCTGGCCCGCCTCAAGGCAATCGCACCCCAAACC
TTTTCTCAAGGTGGCGGATGGACTTTCGCTCATCCAGCACACCGTGTTGCGCGCCGCTTCGATGCAGCATGTCGTGGAGC
TTGTTACCGTGACGTCCACGGGGCACCTCTTCCTTACGAAAGACGTTTTCGACGAGCTGGATTCCGTTGTTTTGCCACGC
ACCTTTCTGCTTGAGCCTGAGGGTCGGGATACCGCCGCCGCCGTCGCTGCGGCAACCGTCCATGCCAAGGCAACACAGGG
TCCCGATGCTGTTCTGTGTGTTTTTCCCGCCGACCATATGATTGGTGATCTGCCCGCATTTCAAACCGCCATGAACCGGG
CAATCGAACAGGCGCTGCAGGGGCGTATCGCAACCTTGGGGATAACCCCGGATAGGCCAGACACCGCATTCGGCTACATC
GAGGCCGACGGTGAGAAAGTTGTCCGGTTCGTCGAGAAACCGAACGCCGAGACTGCCAAATCTTATGTCGCGTCCAAACG
TTTCTTCTGGAACGCCGGCATCTTCTGCTTCAAGGCGCAGGTCATGCTCGACGAAATGGCTGCGCATTGCCCGCAGGTGA
TCGATGCCGTTCTCGATAGCTATGATAATGCTCGCGTCAGCCACGGCGAACATGTTGCCAGCGTCGAACTCTCATCTGAG
CACTTCGCCATGGCGCCGCGTATTTCACTCGACCATGCGGTGATGGAAAAAACCCACAATCTCGCTGTCGTTCCCTGCGA
AATGGGGTGGAACGACATTGGATCTTGGAACGCAATGGCCGAACTGGTCGCCGCTGACGGGAGCGGCAACAGGATTCGCG
GCGATGTCCATGTGGTCGACACCGTGGGCAGTTACATAAGCTCGGACAAACGCGTCATCGGCACCGTCGGCATCAGCGAC
CTGGTGATCGTGGATTCCCCCGATGCATTGCTGGTTGCATCCCGCGATCGCGTCCAGGACGTCAAGAAACTCTTCGAGGG
ACTCAAGGCTGCGGGACATGAAGCGCACTTGCTTCACAGTACCGTGCACCGGCCCTGGGGCACCTACACGGTTCTGGAGG
AAAGCGAGCGCTTCAAGATCAAGCGCATCGAGGTGAAGCCGGGCGGACGCTTGAGCCTGCAGATGCACCATCACCGCTCC
GAGCACTGGGTCGTGGTCAGCGGCACTGCGAAAATAGTCAACGGCGACCAGGAGCTACTCCTGACCACTAATCAATCCAC
CTATATCCCTTGCGGCCACAAACACCGGCTCGAAAACCCCGGCAATATCGGACTGGTGATGATCGAGGTCCAAAGCGGCG
AGTATCTCGGCGAAGATGACATCGTGCGGCTTGAGGACGTATACGGTCGAACGTGA

Upstream 100 bases:

>100_bases
ACTCGGAAGCTTCGACCGAGAGCAGGGCCATGGCGATCGTCGCCTCGACGCTGCAAGGGGCACATGCGTTCGCGCTTACA
GACGAGATAGAGGACCTTTG

Downstream 100 bases:

>100_bases
CAGTCCAACGTCACATGCCCTACGGTGGCTGGCAGACCGAACCTGCGTCGGCATGTGGGCTGTCAGGCGACCGGCGGCTA
GGCAAGGCGAGGCAAACCAG

Product: NoeJ; phosphomannose isomerase/GDP-mannose pyrophosphorylase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKVVPVIISGGAGSRLWPASRQSHPKPFLKVADGLSLIQHTVLRAASMQHVVELVTVTSTGHLFLTKDVFDELDSVVLPR
TFLLEPEGRDTAAAVAAATVHAKATQGPDAVLCVFPADHMIGDLPAFQTAMNRAIEQALQGRIATLGITPDRPDTAFGYI
EADGEKVVRFVEKPNAETAKSYVASKRFFWNAGIFCFKAQVMLDEMAAHCPQVIDAVLDSYDNARVSHGEHVASVELSSE
HFAMAPRISLDHAVMEKTHNLAVVPCEMGWNDIGSWNAMAELVAADGSGNRIRGDVHVVDTVGSYISSDKRVIGTVGISD
LVIVDSPDALLVASRDRVQDVKKLFEGLKAAGHEAHLLHSTVHRPWGTYTVLEESERFKIKRIEVKPGGRLSLQMHHHRS
EHWVVVSGTAKIVNGDQELLLTTNQSTYIPCGHKHRLENPGNIGLVMIEVQSGEYLGEDDIVRLEDVYGRT

Sequences:

>Translated_471_residues
MKVVPVIISGGAGSRLWPASRQSHPKPFLKVADGLSLIQHTVLRAASMQHVVELVTVTSTGHLFLTKDVFDELDSVVLPR
TFLLEPEGRDTAAAVAAATVHAKATQGPDAVLCVFPADHMIGDLPAFQTAMNRAIEQALQGRIATLGITPDRPDTAFGYI
EADGEKVVRFVEKPNAETAKSYVASKRFFWNAGIFCFKAQVMLDEMAAHCPQVIDAVLDSYDNARVSHGEHVASVELSSE
HFAMAPRISLDHAVMEKTHNLAVVPCEMGWNDIGSWNAMAELVAADGSGNRIRGDVHVVDTVGSYISSDKRVIGTVGISD
LVIVDSPDALLVASRDRVQDVKKLFEGLKAAGHEAHLLHSTVHRPWGTYTVLEESERFKIKRIEVKPGGRLSLQMHHHRS
EHWVVVSGTAKIVNGDQELLLTTNQSTYIPCGHKHRLENPGNIGLVMIEVQSGEYLGEDDIVRLEDVYGRT
>Mature_471_residues
MKVVPVIISGGAGSRLWPASRQSHPKPFLKVADGLSLIQHTVLRAASMQHVVELVTVTSTGHLFLTKDVFDELDSVVLPR
TFLLEPEGRDTAAAVAAATVHAKATQGPDAVLCVFPADHMIGDLPAFQTAMNRAIEQALQGRIATLGITPDRPDTAFGYI
EADGEKVVRFVEKPNAETAKSYVASKRFFWNAGIFCFKAQVMLDEMAAHCPQVIDAVLDSYDNARVSHGEHVASVELSSE
HFAMAPRISLDHAVMEKTHNLAVVPCEMGWNDIGSWNAMAELVAADGSGNRIRGDVHVVDTVGSYISSDKRVIGTVGISD
LVIVDSPDALLVASRDRVQDVKKLFEGLKAAGHEAHLLHSTVHRPWGTYTVLEESERFKIKRIEVKPGGRLSLQMHHHRS
EHWVVVSGTAKIVNGDQELLLTTNQSTYIPCGHKHRLENPGNIGLVMIEVQSGEYLGEDDIVRLEDVYGRT

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=481, Percent_Identity=43.2432432432432, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51441; Mature: 51441

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVPVIISGGAGSRLWPASRQSHPKPFLKVADGLSLIQHTVLRAASMQHVVELVTVTST
CEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
GHLFLTKDVFDELDSVVLPRTFLLEPEGRDTAAAVAAATVHAKATQGPDAVLCVFPADHM
CCEEEEHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHEEEECCCCCCEEEEEECCHHH
IGDLPAFQTAMNRAIEQALQGRIATLGITPDRPDTAFGYIEADGEKVVRFVEKPNAETAK
HCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHH
SYVASKRFFWNAGIFCFKAQVMLDEMAAHCPQVIDAVLDSYDNARVSHGEHVASVELSSE
HHHHHCCEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCC
HFAMAPRISLDHAVMEKTHNLAVVPCEMGWNDIGSWNAMAELVAADGSGNRIRGDVHVVD
CEEECCCCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHEEECCCCCEEECCEEEEE
TVGSYISSDKRVIGTVGISDLVIVDSPDALLVASRDRVQDVKKLFEGLKAAGHEAHLLHS
HHHHHHCCCCEEEEEECCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHH
TVHRPWGTYTVLEESERFKIKRIEVKPGGRLSLQMHHHRSEHWVVVSGTAKIVNGDQELL
HHCCCCCCEEEEECCCCEEEEEEEECCCCEEEEEEECCCCCCEEEEECCEEEECCCCEEE
LTTNQSTYIPCGHKHRLENPGNIGLVMIEVQSGEYLGEDDIVRLEDVYGRT
EEECCCEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEHHHCCCC
>Mature Secondary Structure
MKVVPVIISGGAGSRLWPASRQSHPKPFLKVADGLSLIQHTVLRAASMQHVVELVTVTST
CEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
GHLFLTKDVFDELDSVVLPRTFLLEPEGRDTAAAVAAATVHAKATQGPDAVLCVFPADHM
CCEEEEHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHEEEECCCCCCEEEEEECCHHH
IGDLPAFQTAMNRAIEQALQGRIATLGITPDRPDTAFGYIEADGEKVVRFVEKPNAETAK
HCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHH
SYVASKRFFWNAGIFCFKAQVMLDEMAAHCPQVIDAVLDSYDNARVSHGEHVASVELSSE
HHHHHCCEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCC
HFAMAPRISLDHAVMEKTHNLAVVPCEMGWNDIGSWNAMAELVAADGSGNRIRGDVHVVD
CEEECCCCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHEEECCCCCEEECCEEEEE
TVGSYISSDKRVIGTVGISDLVIVDSPDALLVASRDRVQDVKKLFEGLKAAGHEAHLLHS
HHHHHHCCCCEEEEEECCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHH
TVHRPWGTYTVLEESERFKIKRIEVKPGGRLSLQMHHHRSEHWVVVSGTAKIVNGDQELL
HHCCCCCCEEEEECCCCEEEEEEEECCCCEEEEEEECCCCCCEEEEECCEEEECCCCEEE
LTTNQSTYIPCGHKHRLENPGNIGLVMIEVQSGEYLGEDDIVRLEDVYGRT
EEECCCEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]