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The map label for this gene is perR [H]

Identifier: 13474803

GI number: 13474803

Start: 4652345

End: 4653340

Strand: Direct

Name: perR [H]

Synonym: mlr5771

Alternate gene names: 13474803

Gene position: 4652345-4653340 (Clockwise)

Preceding gene: 13474791

Following gene: 13474804

Centisome position: 66.12

GC content: 59.54

Gene sequence:

>996_bases
ATGTCGGATATCAAGTTCAATTCGATGACCCATTTCGAGGCCGTCGCCCGGCTCGGCGGCGTGGCAAAGGCTGCGCAGGA
GTTGCAGGTGACACCTTCAGCGGTCAGCCAGCAACTGCGGTTGCTCGAACACCAACTCGGCGTGCGGCTTTTCCAGCGAG
AAAAGCGCCATCTCTCGCTGACCATCGACGGCGAACGACTTTTCCAGACCACGACCCAGGCCTTCGAATCCATTCGTGAG
GTGCGAAATGCCATTGTTCGCCAGCGCGAAAGCTTCCAGCTCAGCCTTCGCGTCAGTCCTTCTTTCGGCGAGAAGTGGTT
GGCGCCCCGGTTGGCTGAGTTCAGCAAGGACTATCCGAGCTGGAACCTGCGGGTGGACGCCACGCCCAATTTCTCGGACT
TCGAAACCGAGGTCATCGATCTCGATCTACGCTATGGCGACGGTGGCTGGGCTGGCCTTTACTCCGATTGCGTCGTCAAC
GACCTCATCCTTCCGATGTGCTCGCCATCCTATCTGGCGGAGCTGCGCGGACTGTCAGTCGATCCGCGCGAGCAGCTTGG
CCATGCGAGACTGATCGACAGCGTGAAGGCCTATTTCCGGTGGGACTATTGGCTGCCGCGCAACGGTATCCAGGGCGCCC
GCATGACGTATCCCTACCGTTTCGACCGTTCGTCAATGTCGGTTCAATTGGCCAAGGACGGAGCAGGCGTGGTCCTGGAA
AGCACGACAATCGCGTTCGAGGATCTCGTGTCGGGTTCCCTGGTGCCGGTATCGACCGAGTTCGACGTCATTGAGTTTCC
CGGCTATTGGCTGGTCTGTCCTTCCAGGCACATGAACCGGCGCGCGGTCCGCCTGTTTTCCGATTGGGTATCTCGGGTTG
GCCAGCGCGACACCGATCGCGCACGTCAGTTTTTGTCGGAGAGCGGGCTGCATATATCGTTCGAACGACGCCCTCATTTT
GGCACGCCGGATGACAGAGCGGCAACGATGTTGTGA

Upstream 100 bases:

>100_bases
CTCCTCCCGAGACGACAGGATCATGCGACTGATTGACATTCGGCTCAATTCTCGTTTCTTAACATTCTGTGTAGCTGAAC
TTAACTAACTGACCAGAAAG

Downstream 100 bases:

>100_bases
TCAGGATTTCAGAAGAGAACTGGTGGTCTTTCGCTTGCATCGTTCGGAATAATCGAGGCAGCTCTCGGCCCCCCCGCGAA
ATTTCAGATCAGGCGTACTG

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: Peroxide resistance protein perR [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSDIKFNSMTHFEAVARLGGVAKAAQELQVTPSAVSQQLRLLEHQLGVRLFQREKRHLSLTIDGERLFQTTTQAFESIRE
VRNAIVRQRESFQLSLRVSPSFGEKWLAPRLAEFSKDYPSWNLRVDATPNFSDFETEVIDLDLRYGDGGWAGLYSDCVVN
DLILPMCSPSYLAELRGLSVDPREQLGHARLIDSVKAYFRWDYWLPRNGIQGARMTYPYRFDRSSMSVQLAKDGAGVVLE
STTIAFEDLVSGSLVPVSTEFDVIEFPGYWLVCPSRHMNRRAVRLFSDWVSRVGQRDTDRARQFLSESGLHISFERRPHF
GTPDDRAATML

Sequences:

>Translated_331_residues
MSDIKFNSMTHFEAVARLGGVAKAAQELQVTPSAVSQQLRLLEHQLGVRLFQREKRHLSLTIDGERLFQTTTQAFESIRE
VRNAIVRQRESFQLSLRVSPSFGEKWLAPRLAEFSKDYPSWNLRVDATPNFSDFETEVIDLDLRYGDGGWAGLYSDCVVN
DLILPMCSPSYLAELRGLSVDPREQLGHARLIDSVKAYFRWDYWLPRNGIQGARMTYPYRFDRSSMSVQLAKDGAGVVLE
STTIAFEDLVSGSLVPVSTEFDVIEFPGYWLVCPSRHMNRRAVRLFSDWVSRVGQRDTDRARQFLSESGLHISFERRPHF
GTPDDRAATML
>Mature_330_residues
SDIKFNSMTHFEAVARLGGVAKAAQELQVTPSAVSQQLRLLEHQLGVRLFQREKRHLSLTIDGERLFQTTTQAFESIREV
RNAIVRQRESFQLSLRVSPSFGEKWLAPRLAEFSKDYPSWNLRVDATPNFSDFETEVIDLDLRYGDGGWAGLYSDCVVND
LILPMCSPSYLAELRGLSVDPREQLGHARLIDSVKAYFRWDYWLPRNGIQGARMTYPYRFDRSSMSVQLAKDGAGVVLES
TTIAFEDLVSGSLVPVSTEFDVIEFPGYWLVCPSRHMNRRAVRLFSDWVSRVGQRDTDRARQFLSESGLHISFERRPHFG
TPDDRAATML

Specific function: Apparent regulatory gene involved in peroxide resistance in stationary phase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786448, Length=291, Percent_Identity=34.7079037800687, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789173, Length=285, Percent_Identity=29.1228070175439, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788706, Length=257, Percent_Identity=30.3501945525292, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87081978, Length=323, Percent_Identity=27.2445820433437, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693193, Length=306, Percent_Identity=25.1633986928105, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=23.2876712328767, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=36.9747899159664, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37793; Mature: 37662

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIKFNSMTHFEAVARLGGVAKAAQELQVTPSAVSQQLRLLEHQLGVRLFQREKRHLSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TIDGERLFQTTTQAFESIREVRNAIVRQRESFQLSLRVSPSFGEKWLAPRLAEFSKDYPS
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
WNLRVDATPNFSDFETEVIDLDLRYGDGGWAGLYSDCVVNDLILPMCSPSYLAELRGLSV
CEEEEECCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
DPREQLGHARLIDSVKAYFRWDYWLPRNGIQGARMTYPYRFDRSSMSVQLAKDGAGVVLE
CHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEECCEEECCCCCEEEEECCCCCEEEE
STTIAFEDLVSGSLVPVSTEFDVIEFPGYWLVCPSRHMNRRAVRLFSDWVSRVGQRDTDR
CCHHHHHHHHCCCEEEECCCCCEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHH
ARQFLSESGLHISFERRPHFGTPDDRAATML
HHHHHHHCCCEEEEECCCCCCCCCCCHHCCC
>Mature Secondary Structure 
SDIKFNSMTHFEAVARLGGVAKAAQELQVTPSAVSQQLRLLEHQLGVRLFQREKRHLSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TIDGERLFQTTTQAFESIREVRNAIVRQRESFQLSLRVSPSFGEKWLAPRLAEFSKDYPS
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
WNLRVDATPNFSDFETEVIDLDLRYGDGGWAGLYSDCVVNDLILPMCSPSYLAELRGLSV
CEEEEECCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
DPREQLGHARLIDSVKAYFRWDYWLPRNGIQGARMTYPYRFDRSSMSVQLAKDGAGVVLE
CHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEECCEEECCCCCEEEEECCCCCEEEE
STTIAFEDLVSGSLVPVSTEFDVIEFPGYWLVCPSRHMNRRAVRLFSDWVSRVGQRDTDR
CCHHHHHHHHCCCEEEECCCCCEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHH
ARQFLSESGLHISFERRPHFGTPDDRAATML
HHHHHHHCCCEEEEECCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]