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The map label for this gene is rprX [H]

Identifier: 13474773

GI number: 13474773

Start: 4618555

End: 4620033

Strand: Direct

Name: rprX [H]

Synonym: mlr5737

Alternate gene names: 13474773

Gene position: 4618555-4620033 (Clockwise)

Preceding gene: 13474771

Following gene: 13474774

Centisome position: 65.64

GC content: 61.87

Gene sequence:

>1479_bases
ATGCTGCGTGGCTCCAGCGCTCTGCTGGCGATGGGCCTGCTGGTTCTGATGGGCATCGTCACCGCCACATACCTGCTCGC
CGAGAAGTCGCGCATCAGCTTCGACGATGTGATCGCGGCGCGCGACACGCGCACCGCCGCCGTCGATGTCCGCAATTCGC
TGCTCTCGGCGGAATCCAGTCAGCGGGGTTTCCTCTTAAACGGCAACGAGATCTATCTCTCGCCTTACGATACGGCAAAG
TCTTCGGCTCTTCGCCGGTTCGAAAAGTTGCAGCTCCTCGTTGCCGGCGAACCCGAGACTGCGGCATCGATCGACCAGCT
CAAGGCAATCATCGGCGAAAAACTTGCCGAAATGGACAAGACCGTCGCCCTGAAGCGACAGCGCAAGGACGATGCCGTGG
CGGCGATCGTCGCTTCCAACCGTGGCAAGACGCTGATGGATCAGGCCAACGTCTACTTCAACGGCATCATCCTTGCGGCC
GACGACCGGCTGACCGCGCGGGTGGCGGAACAACGGTCCTACTTCGCCTGGCTGCGCATGATTACCATAGCCGGCGGCAT
AGCGATCGTTATCGTGGTCGGCTTTGCCTGGGCGTCGCTCTTGCGCCACACGCGCGAACTCAGCGCCGCGCGGCGAAACC
TCGAGGCTCTCAACAGCGGGCTGGAAACCAGGGTGCGCGAGCGCACCGCCGACCTGGTGCGGGCCAATGAAGAGGTTCAG
CGCTTCGCATACATCGTCACCCATGACCTGCGCGCGCCTCTCGTCAACATCATGGGTTTCACCAGCGAGCTGGAAGCAGG
CGTCGCCAGCCTGCAGACGCTCATCGAAAAGTCCGGCATCGGCGCCAACGCGTCCGACCCCCTCGTTGCCAACGCACGAG
TGGCGGCGGCGGAGGACCTGCCGGAAGCCATCGGTTTCATCCGCTCGTCGACGCGCAAAATGGATGGGCTCATCAACGCC
ATCCTCCAGCTTTCGCGCGAGGGACGCAGGCCGTTGCGGCCCGAAACCATTCAACTTGCGTCTTTGATCGAAAGCACCGT
CTCCAGCTTCCAGCATCAGGTCAAGGAAGCGGGCGGGAAGATCGACGTCGATCTCGCAGGCGTTGAGATCGAGGCCGATC
GCCTGTCGCTCGAGCAGGTCTTTGCCAACCTTTTCGACAATGCGACCAAATACCGCTCGCCCGCGCGGCCACTTCGCATC
AGGGTCGGAGCAAGGATTATCCCCGGTGGCCGCATCGCCATCGATTTCGAGGACAATGGCCGCGGCGTCGCCGAGCAGGA
CGTGGAACGCATTTTCGAGCTGTTTCGGCGATCGGGTCTACAGGACCTGCCTGGCGACGGTATCGGACTTGCGCATGTAC
GAGCCATCCTGCGCAGGCTAGGCGGCGATATCACGGTCAAATCAAAGCTCGACGTTGGGACAACTTTCAGGATAGAGCTG
CCGCTGATCGCGGCATCAAACGAAAGAGCGTTTGCATGA

Upstream 100 bases:

>100_bases
CGGCGCGTCGGTTGTGGGAAAGTATAACGCTCGCTAGAGATAACGCCACCAATGCGCACCCAGTGAGACGAATTTGTCTG
AAAATCCAACCGACAAGGTC

Downstream 100 bases:

>100_bases
GCCAAGCCGGCAAACCTGTAACGATCGTCATGATCGAGGACGATGAGGGCCATGCGCGTCTCATCGAGAAGAACATTCGC
CGCGCCGGCGTCAACAACGA

Product: two-component sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MLRGSSALLAMGLLVLMGIVTATYLLAEKSRISFDDVIAARDTRTAAVDVRNSLLSAESSQRGFLLNGNEIYLSPYDTAK
SSALRRFEKLQLLVAGEPETAASIDQLKAIIGEKLAEMDKTVALKRQRKDDAVAAIVASNRGKTLMDQANVYFNGIILAA
DDRLTARVAEQRSYFAWLRMITIAGGIAIVIVVGFAWASLLRHTRELSAARRNLEALNSGLETRVRERTADLVRANEEVQ
RFAYIVTHDLRAPLVNIMGFTSELEAGVASLQTLIEKSGIGANASDPLVANARVAAAEDLPEAIGFIRSSTRKMDGLINA
ILQLSREGRRPLRPETIQLASLIESTVSSFQHQVKEAGGKIDVDLAGVEIEADRLSLEQVFANLFDNATKYRSPARPLRI
RVGARIIPGGRIAIDFEDNGRGVAEQDVERIFELFRRSGLQDLPGDGIGLAHVRAILRRLGGDITVKSKLDVGTTFRIEL
PLIAASNERAFA

Sequences:

>Translated_492_residues
MLRGSSALLAMGLLVLMGIVTATYLLAEKSRISFDDVIAARDTRTAAVDVRNSLLSAESSQRGFLLNGNEIYLSPYDTAK
SSALRRFEKLQLLVAGEPETAASIDQLKAIIGEKLAEMDKTVALKRQRKDDAVAAIVASNRGKTLMDQANVYFNGIILAA
DDRLTARVAEQRSYFAWLRMITIAGGIAIVIVVGFAWASLLRHTRELSAARRNLEALNSGLETRVRERTADLVRANEEVQ
RFAYIVTHDLRAPLVNIMGFTSELEAGVASLQTLIEKSGIGANASDPLVANARVAAAEDLPEAIGFIRSSTRKMDGLINA
ILQLSREGRRPLRPETIQLASLIESTVSSFQHQVKEAGGKIDVDLAGVEIEADRLSLEQVFANLFDNATKYRSPARPLRI
RVGARIIPGGRIAIDFEDNGRGVAEQDVERIFELFRRSGLQDLPGDGIGLAHVRAILRRLGGDITVKSKLDVGTTFRIEL
PLIAASNERAFA
>Mature_492_residues
MLRGSSALLAMGLLVLMGIVTATYLLAEKSRISFDDVIAARDTRTAAVDVRNSLLSAESSQRGFLLNGNEIYLSPYDTAK
SSALRRFEKLQLLVAGEPETAASIDQLKAIIGEKLAEMDKTVALKRQRKDDAVAAIVASNRGKTLMDQANVYFNGIILAA
DDRLTARVAEQRSYFAWLRMITIAGGIAIVIVVGFAWASLLRHTRELSAARRNLEALNSGLETRVRERTADLVRANEEVQ
RFAYIVTHDLRAPLVNIMGFTSELEAGVASLQTLIEKSGIGANASDPLVANARVAAAEDLPEAIGFIRSSTRKMDGLINA
ILQLSREGRRPLRPETIQLASLIESTVSSFQHQVKEAGGKIDVDLAGVEIEADRLSLEQVFANLFDNATKYRSPARPLRI
RVGARIIPGGRIAIDFEDNGRGVAEQDVERIFELFRRSGLQDLPGDGIGLAHVRAILRRLGGDITVKSKLDVGTTFRIEL
PLIAASNERAFA

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082128, Length=351, Percent_Identity=22.7920227920228, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=321, Percent_Identity=22.1183800623053, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=27.6679841897233, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI48994928, Length=278, Percent_Identity=24.4604316546763, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=24.609375, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53642; Mature: 53642

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGSSALLAMGLLVLMGIVTATYLLAEKSRISFDDVIAARDTRTAAVDVRNSLLSAESS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCC
QRGFLLNGNEIYLSPYDTAKSSALRRFEKLQLLVAGEPETAASIDQLKAIIGEKLAEMDK
CCCEEEECCEEEECCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TVALKRQRKDDAVAAIVASNRGKTLMDQANVYFNGIILAADDRLTARVAEQRSYFAWLRM
HHHHHHHCCCCCEEEEEECCCCCCHHHCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHH
ITIAGGIAIVIVVGFAWASLLRHTRELSAARRNLEALNSGLETRVRERTADLVRANEEVQ
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFAYIVTHDLRAPLVNIMGFTSELEAGVASLQTLIEKSGIGANASDPLVANARVAAAEDL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHH
PEAIGFIRSSTRKMDGLINAILQLSREGRRPLRPETIQLASLIESTVSSFQHQVKEAGGK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
IDVDLAGVEIEADRLSLEQVFANLFDNATKYRSPARPLRIRVGARIIPGGRIAIDFEDNG
EEEEEECEEEEHHHHHHHHHHHHHHHCHHHHCCCCCCEEEEECCEECCCCEEEEEECCCC
RGVAEQDVERIFELFRRSGLQDLPGDGIGLAHVRAILRRLGGDITVKSKLDVGTTFRIEL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEEEE
PLIAASNERAFA
EEEEECCCCCCC
>Mature Secondary Structure
MLRGSSALLAMGLLVLMGIVTATYLLAEKSRISFDDVIAARDTRTAAVDVRNSLLSAESS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCC
QRGFLLNGNEIYLSPYDTAKSSALRRFEKLQLLVAGEPETAASIDQLKAIIGEKLAEMDK
CCCEEEECCEEEECCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TVALKRQRKDDAVAAIVASNRGKTLMDQANVYFNGIILAADDRLTARVAEQRSYFAWLRM
HHHHHHHCCCCCEEEEEECCCCCCHHHCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHH
ITIAGGIAIVIVVGFAWASLLRHTRELSAARRNLEALNSGLETRVRERTADLVRANEEVQ
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFAYIVTHDLRAPLVNIMGFTSELEAGVASLQTLIEKSGIGANASDPLVANARVAAAEDL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHH
PEAIGFIRSSTRKMDGLINAILQLSREGRRPLRPETIQLASLIESTVSSFQHQVKEAGGK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
IDVDLAGVEIEADRLSLEQVFANLFDNATKYRSPARPLRIRVGARIIPGGRIAIDFEDNG
EEEEEECEEEEHHHHHHHHHHHHHHHCHHHHCCCCCCEEEEECCEECCCCEEEEEECCCC
RGVAEQDVERIFELFRRSGLQDLPGDGIGLAHVRAILRRLGGDITVKSKLDVGTTFRIEL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEEEE
PLIAASNERAFA
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]