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The map label for this gene is lig [H]

Identifier: 13474573

GI number: 13474573

Start: 4397808

End: 4398815

Strand: Reverse

Name: lig [H]

Synonym: mll5484

Alternate gene names: 13474573

Gene position: 4398815-4397808 (Counterclockwise)

Preceding gene: 13474577

Following gene: 161621447

Centisome position: 62.52

GC content: 66.47

Gene sequence:

>1008_bases
ATGCGCGCCAGCGACCTGCTTCATCCCCGGCCCGAAGGCCTTTACTGTCCACCGGGCGATTTCTTCATCGACCCGGTGCG
GCCGGTGAACCGGGCGCTGATCACGCACGGCCATTCCGACCATGCGCGTTCCGGCCACCGCTCGGTGCTGGCGACGCAGC
AGACGCTCGACATTATGGCCCTGCGCTACGGCGAGGACTTTGCCGGAACGACCCAAGCCGCACGGCTCGGCGAGACGATC
GCTCTCGACAGCGTCAGCGTCAGCTTCCATCCGGCCGGGCATGTGCTGGGTTCGGCGCAGATATCGGTCGAGCATCAGGG
CACGCGCATCGTCGCCTCCGGCGATTACAAACGGCAAAAGGATGCGACCTGCGCGCCGTTCGAACCGATCCGCTGCGACG
TCTTCATCACCGAGGCGACTTTCGGCCTGCCGGTGTTTCGCCATCCACCCGACACGGAAGAGATCGCCCGCCTGCTGAAA
TCGGCGGCGCAATTTCCCGAACGCTCGCATCTGGTCGGCGCCTATGCGCTGGGCAAGGCGCAGCGGGTGATGCGGCTGTT
GCGCGACGCCGGCTATGACAGGCCGCTCTACATCCATGGCGCGCTGGCCAGGCTCAGCGAATACTATCAGAGCCAGGGTA
TCGACCTGGGTGTCCTCGAGCCGGCAACGGTCGAGGGCGGCAAGGATGACTTCACCGGCGCTATCGTCGTCGGCCCGCCA
TCGGCCTTCGCCGATCGCTGGGCGCGGCGCTTTCCCGATCCGATCTCGTGCTTCGCGTCGGGCTGGATGCGGATCCGCCA
GCGCGCCAAGCAAGGCGGCGTCGAACTGCCGCTGATCATATCGGACCATGCCGACTGGGACGAACTCACCGCCACCATCA
AGGAGACCGGCGCCGAGGAGATCTGGGTGACGCATGGCCGCGAGGAGGCCCTCGTGCGCTGGTGCGAGCTCGAAGGCATC
GCCGCCCGGCCGTTGCATCTGGTGGGGTATGAGGACGAGGGCGATTGA

Upstream 100 bases:

>100_bases
ATGCGGAAGCTGAACCGAATTGAGCGCCCTTTGCCCAGGAGAGTCAGCAGTCTCCGACATCAGGCTTCCCGCAGCGGAAT
TATATCCTATCTTGGGGACC

Downstream 100 bases:

>100_bases
AGGCATGAACCGCTTCGCCGAACTTCTCGACCGCCTGGTGCTGACGCCGTCGCGCAACGGCAAGCTGACGCTGCTGGTCG
ACTATTTCCGAACCGTCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRASDLLHPRPEGLYCPPGDFFIDPVRPVNRALITHGHSDHARSGHRSVLATQQTLDIMALRYGEDFAGTTQAARLGETI
ALDSVSVSFHPAGHVLGSAQISVEHQGTRIVASGDYKRQKDATCAPFEPIRCDVFITEATFGLPVFRHPPDTEEIARLLK
SAAQFPERSHLVGAYALGKAQRVMRLLRDAGYDRPLYIHGALARLSEYYQSQGIDLGVLEPATVEGGKDDFTGAIVVGPP
SAFADRWARRFPDPISCFASGWMRIRQRAKQGGVELPLIISDHADWDELTATIKETGAEEIWVTHGREEALVRWCELEGI
AARPLHLVGYEDEGD

Sequences:

>Translated_335_residues
MRASDLLHPRPEGLYCPPGDFFIDPVRPVNRALITHGHSDHARSGHRSVLATQQTLDIMALRYGEDFAGTTQAARLGETI
ALDSVSVSFHPAGHVLGSAQISVEHQGTRIVASGDYKRQKDATCAPFEPIRCDVFITEATFGLPVFRHPPDTEEIARLLK
SAAQFPERSHLVGAYALGKAQRVMRLLRDAGYDRPLYIHGALARLSEYYQSQGIDLGVLEPATVEGGKDDFTGAIVVGPP
SAFADRWARRFPDPISCFASGWMRIRQRAKQGGVELPLIISDHADWDELTATIKETGAEEIWVTHGREEALVRWCELEGI
AARPLHLVGYEDEGD
>Mature_335_residues
MRASDLLHPRPEGLYCPPGDFFIDPVRPVNRALITHGHSDHARSGHRSVLATQQTLDIMALRYGEDFAGTTQAARLGETI
ALDSVSVSFHPAGHVLGSAQISVEHQGTRIVASGDYKRQKDATCAPFEPIRCDVFITEATFGLPVFRHPPDTEEIARLLK
SAAQFPERSHLVGAYALGKAQRVMRLLRDAGYDRPLYIHGALARLSEYYQSQGIDLGVLEPATVEGGKDDFTGAIVVGPP
SAFADRWARRFPDPISCFASGWMRIRQRAKQGGVELPLIISDHADWDELTATIKETGAEEIWVTHGREEALVRWCELEGI
AARPLHLVGYEDEGD

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 36912; Mature: 36912

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASDLLHPRPEGLYCPPGDFFIDPVRPVNRALITHGHSDHARSGHRSVLATQQTLDIMA
CCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHH
LRYGEDFAGTTQAARLGETIALDSVSVSFHPAGHVLGSAQISVEHQGTRIVASGDYKRQK
EECCCCCCCCHHHHHCCCEEEEEEEEEEECCCCCEECCEEEEEEECCCEEEECCCCCCCC
DATCAPFEPIRCDVFITEATFGLPVFRHPPDTEEIARLLKSAAQFPERSHLVGAYALGKA
CCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHCEEEHHHHHHH
QRVMRLLRDAGYDRPLYIHGALARLSEYYQSQGIDLGVLEPATVEGGKDDFTGAIVVGPP
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEECCC
SAFADRWARRFPDPISCFASGWMRIRQRAKQGGVELPLIISDHADWDELTATIKETGAEE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCE
IWVTHGREEALVRWCELEGIAARPLHLVGYEDEGD
EEEECCCHHHHHHHHHCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRASDLLHPRPEGLYCPPGDFFIDPVRPVNRALITHGHSDHARSGHRSVLATQQTLDIMA
CCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHH
LRYGEDFAGTTQAARLGETIALDSVSVSFHPAGHVLGSAQISVEHQGTRIVASGDYKRQK
EECCCCCCCCHHHHHCCCEEEEEEEEEEECCCCCEECCEEEEEEECCCEEEECCCCCCCC
DATCAPFEPIRCDVFITEATFGLPVFRHPPDTEEIARLLKSAAQFPERSHLVGAYALGKA
CCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHCEEEHHHHHHH
QRVMRLLRDAGYDRPLYIHGALARLSEYYQSQGIDLGVLEPATVEGGKDDFTGAIVVGPP
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEECCC
SAFADRWARRFPDPISCFASGWMRIRQRAKQGGVELPLIISDHADWDELTATIKETGAEE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCE
IWVTHGREEALVRWCELEGIAARPLHLVGYEDEGD
EEEECCCHHHHHHHHHCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA