Click here to switch to the map view.

The map label for this gene is sigW [H]

Identifier: 13474550

GI number: 13474550

Start: 4372798

End: 4373346

Strand: Reverse

Name: sigW [H]

Synonym: mll5456

Alternate gene names: 13474550

Gene position: 4373346-4372798 (Counterclockwise)

Preceding gene: 13474551

Following gene: 13474549

Centisome position: 62.16

GC content: 69.22

Gene sequence:

>549_bases
GTGCACCAGCCGATGAGCGCGGATCCGGACGAGGAGTTGGTTCGCCGGGTCGGTGCCGGCGACCCGGCGGCCGTGCAGAC
GCTCGTCGCGCGCAAATTGCCGCGCATCCTTTCGCTTGCCGTGCGCATGCTGGGCGACGCGGCGGAGGCCGAGGATGTCG
CGCAGGAAACCTTCGTGCGCATCTGGCGCCACGCCGCGAGCTGGCGGCGCGGCAATGCACGCTTCGACAGCTGGATCCAC
CGGGTGACGCTCAACCTCTGCTACGACCGGCTGCGCCGGCGCCGCGAGCAGGTGACCGACGATTTGCCGGACATGGCCGA
CCCTTCCCCGCTTCCCGACGCCCGCGAAGAGCCGCACCGTGTCGAGCAGGCCTTGCAGGCGATCGCGCCACGCCAGCGCG
AGGCGATCATCCTGGTCTACTACCAGGAGATGTCCAACATAGAGGCGGCCGCGACCCTGGAGATCAGCGTCGATGCGCTG
GAGAGCCTGCTTTCGCGCGGCCGGCGGGCCTTGCAGATGATCCTGGCCAGGGATGGCGTCCATGACTGA

Upstream 100 bases:

>100_bases
TGGCGACGGCGTTCTGACGGCCGACGAGATGCCAAGCCACAAATCCGCTCCCAAGCCGGAGCAATGACCAAGAGGCCATG
ACGCGTGATGGATATCGGGA

Downstream 100 bases:

>100_bases
GAAGAGCGCGACCATGAATGGCGGACATTTGCCGCGCTCTACGAGCGTCCGGCGGAGGCCGATCGGCCTCGTTTCCAACC
CGCGTGGGCACGCGGCACCA

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MHQPMSADPDEELVRRVGAGDPAAVQTLVARKLPRILSLAVRMLGDAAEAEDVAQETFVRIWRHAASWRRGNARFDSWIH
RVTLNLCYDRLRRRREQVTDDLPDMADPSPLPDAREEPHRVEQALQAIAPRQREAIILVYYQEMSNIEAAATLEISVDAL
ESLLSRGRRALQMILARDGVHD

Sequences:

>Translated_182_residues
MHQPMSADPDEELVRRVGAGDPAAVQTLVARKLPRILSLAVRMLGDAAEAEDVAQETFVRIWRHAASWRRGNARFDSWIH
RVTLNLCYDRLRRRREQVTDDLPDMADPSPLPDAREEPHRVEQALQAIAPRQREAIILVYYQEMSNIEAAATLEISVDAL
ESLLSRGRRALQMILARDGVHD
>Mature_182_residues
MHQPMSADPDEELVRRVGAGDPAAVQTLVARKLPRILSLAVRMLGDAAEAEDVAQETFVRIWRHAASWRRGNARFDSWIH
RVTLNLCYDRLRRRREQVTDDLPDMADPSPLPDAREEPHRVEQALQAIAPRQREAIILVYYQEMSNIEAAATLEISVDAL
ESLLSRGRRALQMILARDGVHD

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20680; Mature: 20680

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQPMSADPDEELVRRVGAGDPAAVQTLVARKLPRILSLAVRMLGDAAEAEDVAQETFVR
CCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IWRHAASWRRGNARFDSWIHRVTLNLCYDRLRRRREQVTDDLPDMADPSPLPDAREEPHR
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
VEQALQAIAPRQREAIILVYYQEMSNIEAAATLEISVDALESLLSRGRRALQMILARDGV
HHHHHHHHCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HD
CC
>Mature Secondary Structure
MHQPMSADPDEELVRRVGAGDPAAVQTLVARKLPRILSLAVRMLGDAAEAEDVAQETFVR
CCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IWRHAASWRRGNARFDSWIHRVTLNLCYDRLRRRREQVTDDLPDMADPSPLPDAREEPHR
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
VEQALQAIAPRQREAIILVYYQEMSNIEAAATLEISVDALESLLSRGRRALQMILARDGV
HHHHHHHHCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]