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The map label for this gene is dhaK [H]

Identifier: 13474417

GI number: 13474417

Start: 4222827

End: 4224470

Strand: Reverse

Name: dhaK [H]

Synonym: mll5296

Alternate gene names: 13474417

Gene position: 4224470-4222827 (Counterclockwise)

Preceding gene: 13474418

Following gene: 13474416

Centisome position: 60.04

GC content: 67.21

Gene sequence:

>1644_bases
ATGAAGCACTTTTTCAACCGCAGGGAAACGATCGTCACCGAGGCGCTGGACGGCCTGTTGCGCACCATCGGCTCAGGCGA
TCTCGCGCGCCTCGACGGCTATCCCGAGATCAAGGTCGTGCTGCGCGCCGACTGGGACAAGTCGAGGGTCAGCGTCGTTT
CCGGCGGCGGCGCCGGGCATGAGCCTTCGCATGCCGGCTTTGTCGGCAAGGGCATGCTGACGGCGGCGGTCTCGGGCGAG
ATCTTCGCCTCGCCGAGCGTCGAAGCGGTGCTCGCTGCCATCCGCGCGGTCACCGGCCCGGCCGGCTGTCTGCTTATCGT
CAAGAACTACACCGGCGACCGGCTCAATTTCGGCCTAGCGGCGGAAAAGGCGCGCGCCGAGGGCTTTCGCGTCGAGATGG
TGATCGTTGCCGACGACATCGCGCTGCCCGATATCGCCCAGCCGCGCGGCGTCGCCGGTACCCTGTTCGTGCACAAGATT
TCCGGCCATCTGTCGGAGGCCGGCCACAATCTGGCTGATATCGCGGCGGCGGCACGGGCGGCGGCAAAGGATATCGTTTC
GCTCGGCATGTCGCTGTCCTCCTGTTCCATCCCCGGCCAGCCGCATGAAGACAGGTTTGGCGCGGACGACGGCGAACTTG
GCCTTGGCATTCATGGCGAGCCGGGCGTCGAGCGGATTGCCTTGCAAAGCGTCGACAGGCTGGTCGCGATCATGGCGGAG
CGCCTCGCAGCAGGGCTCGACCCGAAGGCGAGCCATGCCTTGCTGATCAACAATCTCGGCGCGGTGCCGCCCCTCGAAAT
GTCGCTGATTGCCAATGCGGTGCTAGCCTCGCCACTGGCCAAGACTGTCAAGCTGACGATCGGCCCCGGCCCGCTGATGA
CGGCGCTCAACATGAACGGCTTCTCGTTGTCGCTGATCCGGCTCGATGCGGCGCGCGAAGCAGCCCTGCTGGCGCCGGTC
GGCCCGCATGCCTGGATGCCGGCCAAGCCGGTCGCGGCACCTGTCATCGTGCCGATGGCGAAGGCAGCCGGACAAAGTGT
TGCGCACAAGGCCAGCCAGGATGCCAGCAGCAGGCGCCTGATCGTCACGGTCTGCGAAAAATTGATCTCGCTCGAAGCGT
CATTGAACGGGCTCGACGCCAAGGCGGGCGACGGCGACACCGGCTCGACGGTGGCGACCGGCGCGCGCAGCATCCTGGAA
CGGCTCGACGTCCTGCCGCTGGCGAACCCTGCGGCGACGCTTGGCGCAATCGGCGACATATTGAGTTCGTCGATGGGCGG
CTCGAGCGGGGTGCTGCTGTCGATCTTCTTCACGGCGGCGGCACAGGTCCTCGGTGGCGGCGCCAGTCTGTCCAAGGCAC
TGCTTGCCGGGCTCGAGCGGATGACTTTCTACGGCGGCGCCAAACCGGGTGATCGCACCATGGTCGATGCGCTGGAGCCC
GCGCTAAAAGCGCTCGACGCCGATGGCCTGGAGGAGGCAGCGGCCGCCGCCCAGCGCGGGGCCGAGGCGACAGCCGCCAT
GGAAAAGGCGAAGGCCGGACGGTCGGCCTATGTCGGCACCAAATTGCAAGGCGTGGTCGACCCCGGCGCCCATGCGGTGG
CCGAGGTGTTTTCGGCCGCCGCCACGCTGCTCGTCACGGCCTGA

Upstream 100 bases:

>100_bases
TTTCGGCGCCAATGGACAAAGATTGATGTGAACGGTTTCGGTGTTTCCAGCCGGCGCAGCGCCGCTTCTGATTGACGATT
GCGAATACGGGACGAATTCG

Downstream 100 bases:

>100_bases
CGCATGCACCAGTTGTCGAATGACCGTTCTTTCGCTACTGCCAGCAGACTGGAAACCGGGATTTTGGGCGACATGGCGGC
GTTGAACCTTGCCAGGCTGA

Product: dihydroxyacetone kinase

Products: NA

Alternate protein names: DHA kinase; Glycerone kinase [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MKHFFNRRETIVTEALDGLLRTIGSGDLARLDGYPEIKVVLRADWDKSRVSVVSGGGAGHEPSHAGFVGKGMLTAAVSGE
IFASPSVEAVLAAIRAVTGPAGCLLIVKNYTGDRLNFGLAAEKARAEGFRVEMVIVADDIALPDIAQPRGVAGTLFVHKI
SGHLSEAGHNLADIAAAARAAAKDIVSLGMSLSSCSIPGQPHEDRFGADDGELGLGIHGEPGVERIALQSVDRLVAIMAE
RLAAGLDPKASHALLINNLGAVPPLEMSLIANAVLASPLAKTVKLTIGPGPLMTALNMNGFSLSLIRLDAAREAALLAPV
GPHAWMPAKPVAAPVIVPMAKAAGQSVAHKASQDASSRRLIVTVCEKLISLEASLNGLDAKAGDGDTGSTVATGARSILE
RLDVLPLANPAATLGAIGDILSSSMGGSSGVLLSIFFTAAAQVLGGGASLSKALLAGLERMTFYGGAKPGDRTMVDALEP
ALKALDADGLEEAAAAAQRGAEATAAMEKAKAGRSAYVGTKLQGVVDPGAHAVAEVFSAAATLLVTA

Sequences:

>Translated_547_residues
MKHFFNRRETIVTEALDGLLRTIGSGDLARLDGYPEIKVVLRADWDKSRVSVVSGGGAGHEPSHAGFVGKGMLTAAVSGE
IFASPSVEAVLAAIRAVTGPAGCLLIVKNYTGDRLNFGLAAEKARAEGFRVEMVIVADDIALPDIAQPRGVAGTLFVHKI
SGHLSEAGHNLADIAAAARAAAKDIVSLGMSLSSCSIPGQPHEDRFGADDGELGLGIHGEPGVERIALQSVDRLVAIMAE
RLAAGLDPKASHALLINNLGAVPPLEMSLIANAVLASPLAKTVKLTIGPGPLMTALNMNGFSLSLIRLDAAREAALLAPV
GPHAWMPAKPVAAPVIVPMAKAAGQSVAHKASQDASSRRLIVTVCEKLISLEASLNGLDAKAGDGDTGSTVATGARSILE
RLDVLPLANPAATLGAIGDILSSSMGGSSGVLLSIFFTAAAQVLGGGASLSKALLAGLERMTFYGGAKPGDRTMVDALEP
ALKALDADGLEEAAAAAQRGAEATAAMEKAKAGRSAYVGTKLQGVVDPGAHAVAEVFSAAATLLVTA
>Mature_547_residues
MKHFFNRRETIVTEALDGLLRTIGSGDLARLDGYPEIKVVLRADWDKSRVSVVSGGGAGHEPSHAGFVGKGMLTAAVSGE
IFASPSVEAVLAAIRAVTGPAGCLLIVKNYTGDRLNFGLAAEKARAEGFRVEMVIVADDIALPDIAQPRGVAGTLFVHKI
SGHLSEAGHNLADIAAAARAAAKDIVSLGMSLSSCSIPGQPHEDRFGADDGELGLGIHGEPGVERIALQSVDRLVAIMAE
RLAAGLDPKASHALLINNLGAVPPLEMSLIANAVLASPLAKTVKLTIGPGPLMTALNMNGFSLSLIRLDAAREAALLAPV
GPHAWMPAKPVAAPVIVPMAKAAGQSVAHKASQDASSRRLIVTVCEKLISLEASLNGLDAKAGDGDTGSTVATGARSILE
RLDVLPLANPAATLGAIGDILSSSMGGSSGVLLSIFFTAAAQVLGGGASLSKALLAGLERMTFYGGAKPGDRTMVDALEP
ALKALDADGLEEAAAAAQRGAEATAAMEKAKAGRSAYVGTKLQGVVDPGAHAVAEVFSAAATLLVTA

Specific function: Catalyzes the phosphorylation of dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=569, Percent_Identity=42.8822495606327, Blast_Score=345, Evalue=7e-95,
Organism=Escherichia coli, GI87081857, Length=355, Percent_Identity=34.0845070422535, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1787449, Length=195, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565018, Length=574, Percent_Identity=34.1463414634146, Blast_Score=280, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6323570, Length=572, Percent_Identity=35.6643356643357, Blast_Score=277, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6321055, Length=592, Percent_Identity=34.9662162162162, Blast_Score=258, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR004007
- InterPro:   IPR012734 [H]

Pfam domain/function: PF02733 Dak1; PF02734 Dak2 [H]

EC number: =2.7.1.29 [H]

Molecular weight: Translated: 55557; Mature: 55557

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFFNRRETIVTEALDGLLRTIGSGDLARLDGYPEIKVVLRADWDKSRVSVVSGGGAGH
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEEECCCCCCEEEEECCCCCC
EPSHAGFVGKGMLTAAVSGEIFASPSVEAVLAAIRAVTGPAGCLLIVKNYTGDRLNFGLA
CCCCCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCH
AEKARAEGFRVEMVIVADDIALPDIAQPRGVAGTLFVHKISGHLSEAGHNLADIAAAARA
HHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AAKDIVSLGMSLSSCSIPGQPHEDRFGADDGELGLGIHGEPGVERIALQSVDRLVAIMAE
HHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
RLAAGLDPKASHALLINNLGAVPPLEMSLIANAVLASPLAKTVKLTIGPGPLMTALNMNG
HHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCC
FSLSLIRLDAAREAALLAPVGPHAWMPAKPVAAPVIVPMAKAAGQSVAHKASQDASSRRL
CEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
IVTVCEKLISLEASLNGLDAKAGDGDTGSTVATGARSILERLDVLPLANPAATLGAIGDI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LSSSMGGSSGVLLSIFFTAAAQVLGGGASLSKALLAGLERMTFYGGAKPGDRTMVDALEP
HHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALKALDADGLEEAAAAAQRGAEATAAMEKAKAGRSAYVGTKLQGVVDPGAHAVAEVFSAA
HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHH
ATLLVTA
HHHHCCC
>Mature Secondary Structure
MKHFFNRRETIVTEALDGLLRTIGSGDLARLDGYPEIKVVLRADWDKSRVSVVSGGGAGH
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEEECCCCCCEEEEECCCCCC
EPSHAGFVGKGMLTAAVSGEIFASPSVEAVLAAIRAVTGPAGCLLIVKNYTGDRLNFGLA
CCCCCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCH
AEKARAEGFRVEMVIVADDIALPDIAQPRGVAGTLFVHKISGHLSEAGHNLADIAAAARA
HHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AAKDIVSLGMSLSSCSIPGQPHEDRFGADDGELGLGIHGEPGVERIALQSVDRLVAIMAE
HHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
RLAAGLDPKASHALLINNLGAVPPLEMSLIANAVLASPLAKTVKLTIGPGPLMTALNMNG
HHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCC
FSLSLIRLDAAREAALLAPVGPHAWMPAKPVAAPVIVPMAKAAGQSVAHKASQDASSRRL
CEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
IVTVCEKLISLEASLNGLDAKAGDGDTGSTVATGARSILERLDVLPLANPAATLGAIGDI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LSSSMGGSSGVLLSIFFTAAAQVLGGGASLSKALLAGLERMTFYGGAKPGDRTMVDALEP
HHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALKALDADGLEEAAAAAQRGAEATAAMEKAKAGRSAYVGTKLQGVVDPGAHAVAEVFSAA
HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHH
ATLLVTA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA