Click here to switch to the map view.

The map label for this gene is aglA [H]

Identifier: 13474261

GI number: 13474261

Start: 4047115

End: 4048779

Strand: Reverse

Name: aglA [H]

Synonym: mll5109

Alternate gene names: 13474261

Gene position: 4048779-4047115 (Counterclockwise)

Preceding gene: 13474262

Following gene: 13474260

Centisome position: 57.54

GC content: 64.2

Gene sequence:

>1665_bases
ATGCAATCCGCTTTGAAAGCCAGTTCGAACCCCGACCTCGCCATCGATCGCGACTGGTGGCGAGGTGCTGTCATCTACCA
GATCTACCCGCGCAGCTACCAGGATTCGAACGGCGACGGCATCGGCGACCTCAAGGGCATCATCGAACGGCTGCCCTACA
TCGCAGCGCTCGGTGCGGACGCCATCTGGATCTCGCCCTTCTTCAAATCGCCGATGAAGGATTTCGGCTACGACGTCTCG
GACTATTGCGACGTCGACCCGATGTTCGGCACGCTGGCCGATTTCGACGCGCTGACGGCGGAGGCGCACCGGCTGGGTCT
CAAGGTGATGATCGACGAAGTGCTGTCGCACACGGCCGACATCCATCCCTGGTTCAAGGAAAGCCGGTCGAGCCGCAGCA
ATCCCAAGGCCGACTGGTATGTCTGGGCGGACGCCCGGCCCGACGGCACCCCGCCCAACAACTGGCTGTCGATCTTCGGC
GGGTCCGCCTGGCAGTGGGACACCAGCCGCCAGCAATATTACCTGCACAATTTCCTGGCCGAGCAGCCCGACCTCAACTT
CCACAACCGCGAAGTCCAGGACGCGCTGCTCGACGTCACCCGCTTCTGGCTGGAACGCGGCGTCGACGGCTTCCGCCTCG
ACACGATCAATTTCTACTTTCACAGCCAGGGCCTGGAAAACAATCCGCCGCTGCCGCCGGAAGAACGCAACGACCAGACC
GCGCCGGCGGTCAATCCCTACAACTACCAGGACCATCTCTACGACAAGAGCCGTCCGGAAAACCTCGGCTTCCTCGAACG
CTTCCGCGCTTTGCTCGACGAATATCCGGCAACCGCCGCTGTCGGCGAGGTCGGCGATTCGCAGCGTGGGCTGGAAGTCG
TGGCAGCCTACACTGCCGGCGGCAAGCGCGTGCATATGTGTTATTCCTTCGACTTCCTGGCGCCGGAAAAGATCAGCGCC
GCCAAGGTGCGTTCGGTGCTGGAGGCCTTCGGCAAGGTCGCCAGCGACGGCTGGTCGTGCTGGGCGTTTTCCAATCATGA
CGTGATGCGTCCGGCCTCGCGCTGGGCCGCCGGCGAAGCCGACCCTGTCGCCTATCTCAAGGTCATCTCGGCCTTGCTGA
TGTCGCTGCGCGGCTCGGTCTGCATCTACCAGGGCGAGGAACTCGGGCTGGGCGAGGCCGAATTGCGCTTCGAGGATCTG
CAGGATCCCTATGGCATCCGCTTCTGGCCGGAATTCAAGGGCCGCGACGGCTGCCGCACGCCCATGGTGTGGGATGGCGA
CGCCAAGAATGGCGGCTTCTCCCAGGCCAAGCCCTGGCTGCCGGTGCCGGCCAAGCATCTGGCGCAAGCGGTCAATGTCC
AGCAGGGTGACCAGGCTTCACTGCTCGAGCACTATCGGCGCTTCCTCAGCTTCCGCCGCGCCCATCCGGCGCTGGCCAAG
GGCGACATCACCTTCATCGAAAGCGAGGGCGACACCGTCGCCTTCACGCGCCGCGCCGGCAACGAGCAGGTTGTCTGCGT
CTTCAACCTCGGCGCCAAGCCGGCCAAGGTTGACCTTGGCAGCCGATCCCTGCAACCTTTGCCGGGACACGGGTTTTCCG
GGCAGGCGAGGCCCGGTTCGATCGAGCTTGGCGGTTACGGCGCCTGGTTCGGGCGCATCGACTGA

Upstream 100 bases:

>100_bases
GCCTTCGTGACGATCATCGTGCCGCTGATCGTGTTCTTCTCGCTGCAGCGCTATTTCGTCCGCGGACTGCTTGCCGGTTC
GGTGAAAGGAGGCTGAGACC

Downstream 100 bases:

>100_bases
ATTTTTGAGAAATCACTGGGAGGAAACCAATGGCCGATGTCAATTTGAGGCAAGTGAAGAAGTCCTACGGCAATCTCAAC
ATTCTCCACGGCATCGACCT

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MQSALKASSNPDLAIDRDWWRGAVIYQIYPRSYQDSNGDGIGDLKGIIERLPYIAALGADAIWISPFFKSPMKDFGYDVS
DYCDVDPMFGTLADFDALTAEAHRLGLKVMIDEVLSHTADIHPWFKESRSSRSNPKADWYVWADARPDGTPPNNWLSIFG
GSAWQWDTSRQQYYLHNFLAEQPDLNFHNREVQDALLDVTRFWLERGVDGFRLDTINFYFHSQGLENNPPLPPEERNDQT
APAVNPYNYQDHLYDKSRPENLGFLERFRALLDEYPATAAVGEVGDSQRGLEVVAAYTAGGKRVHMCYSFDFLAPEKISA
AKVRSVLEAFGKVASDGWSCWAFSNHDVMRPASRWAAGEADPVAYLKVISALLMSLRGSVCIYQGEELGLGEAELRFEDL
QDPYGIRFWPEFKGRDGCRTPMVWDGDAKNGGFSQAKPWLPVPAKHLAQAVNVQQGDQASLLEHYRRFLSFRRAHPALAK
GDITFIESEGDTVAFTRRAGNEQVVCVFNLGAKPAKVDLGSRSLQPLPGHGFSGQARPGSIELGGYGAWFGRID

Sequences:

>Translated_554_residues
MQSALKASSNPDLAIDRDWWRGAVIYQIYPRSYQDSNGDGIGDLKGIIERLPYIAALGADAIWISPFFKSPMKDFGYDVS
DYCDVDPMFGTLADFDALTAEAHRLGLKVMIDEVLSHTADIHPWFKESRSSRSNPKADWYVWADARPDGTPPNNWLSIFG
GSAWQWDTSRQQYYLHNFLAEQPDLNFHNREVQDALLDVTRFWLERGVDGFRLDTINFYFHSQGLENNPPLPPEERNDQT
APAVNPYNYQDHLYDKSRPENLGFLERFRALLDEYPATAAVGEVGDSQRGLEVVAAYTAGGKRVHMCYSFDFLAPEKISA
AKVRSVLEAFGKVASDGWSCWAFSNHDVMRPASRWAAGEADPVAYLKVISALLMSLRGSVCIYQGEELGLGEAELRFEDL
QDPYGIRFWPEFKGRDGCRTPMVWDGDAKNGGFSQAKPWLPVPAKHLAQAVNVQQGDQASLLEHYRRFLSFRRAHPALAK
GDITFIESEGDTVAFTRRAGNEQVVCVFNLGAKPAKVDLGSRSLQPLPGHGFSGQARPGSIELGGYGAWFGRID
>Mature_554_residues
MQSALKASSNPDLAIDRDWWRGAVIYQIYPRSYQDSNGDGIGDLKGIIERLPYIAALGADAIWISPFFKSPMKDFGYDVS
DYCDVDPMFGTLADFDALTAEAHRLGLKVMIDEVLSHTADIHPWFKESRSSRSNPKADWYVWADARPDGTPPNNWLSIFG
GSAWQWDTSRQQYYLHNFLAEQPDLNFHNREVQDALLDVTRFWLERGVDGFRLDTINFYFHSQGLENNPPLPPEERNDQT
APAVNPYNYQDHLYDKSRPENLGFLERFRALLDEYPATAAVGEVGDSQRGLEVVAAYTAGGKRVHMCYSFDFLAPEKISA
AKVRSVLEAFGKVASDGWSCWAFSNHDVMRPASRWAAGEADPVAYLKVISALLMSLRGSVCIYQGEELGLGEAELRFEDL
QDPYGIRFWPEFKGRDGCRTPMVWDGDAKNGGFSQAKPWLPVPAKHLAQAVNVQQGDQASLLEHYRRFLSFRRAHPALAK
GDITFIESEGDTVAFTRRAGNEQVVCVFNLGAKPAKVDLGSRSLQPLPGHGFSGQARPGSIELGGYGAWFGRID

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=513, Percent_Identity=33.3333333333333, Blast_Score=284, Evalue=2e-76,
Organism=Escherichia coli, GI1790687, Length=538, Percent_Identity=32.8996282527881, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1786604, Length=513, Percent_Identity=23.9766081871345, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI32565753, Length=525, Percent_Identity=23.2380952380952, Blast_Score=115, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI25147709, Length=518, Percent_Identity=24.9034749034749, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321726, Length=584, Percent_Identity=34.0753424657534, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6322245, Length=549, Percent_Identity=32.6047358834244, Blast_Score=277, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6321731, Length=559, Percent_Identity=33.9892665474061, Blast_Score=276, Evalue=6e-75,
Organism=Saccharomyces cerevisiae, GI6319776, Length=559, Percent_Identity=33.9892665474061, Blast_Score=276, Evalue=8e-75,
Organism=Saccharomyces cerevisiae, GI6324416, Length=583, Percent_Identity=33.6192109777015, Blast_Score=273, Evalue=6e-74,
Organism=Saccharomyces cerevisiae, GI6322241, Length=584, Percent_Identity=32.3630136986301, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6322021, Length=584, Percent_Identity=32.3630136986301, Blast_Score=268, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24583747, Length=547, Percent_Identity=37.6599634369287, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24583749, Length=547, Percent_Identity=37.2943327239488, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24583745, Length=534, Percent_Identity=37.2659176029963, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24586597, Length=543, Percent_Identity=35.7274401473296, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI45549022, Length=522, Percent_Identity=33.5249042145594, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24586589, Length=524, Percent_Identity=35.8778625954198, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24586587, Length=515, Percent_Identity=34.9514563106796, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24586591, Length=519, Percent_Identity=35.0674373795761, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24586593, Length=506, Percent_Identity=36.3636363636364, Blast_Score=305, Evalue=5e-83,
Organism=Drosophila melanogaster, GI24586599, Length=528, Percent_Identity=33.9015151515151, Blast_Score=301, Evalue=8e-82,
Organism=Drosophila melanogaster, GI221330053, Length=530, Percent_Identity=34.7169811320755, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI281360393, Length=446, Percent_Identity=33.1838565022422, Blast_Score=226, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 61999; Mature: 61999

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSALKASSNPDLAIDRDWWRGAVIYQIYPRSYQDSNGDGIGDLKGIIERLPYIAALGAD
CCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCC
AIWISPFFKSPMKDFGYDVSDYCDVDPMFGTLADFDALTAEAHRLGLKVMIDEVLSHTAD
EEEECHHHHCHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IHPWFKESRSSRSNPKADWYVWADARPDGTPPNNWLSIFGGSAWQWDTSRQQYYLHNFLA
CCHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCEECCCCCHHHHHHHHHH
EQPDLNFHNREVQDALLDVTRFWLERGVDGFRLDTINFYFHSQGLENNPPLPPEERNDQT
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCC
APAVNPYNYQDHLYDKSRPENLGFLERFRALLDEYPATAAVGEVGDSQRGLEVVAAYTAG
CCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEEEECC
GKRVHMCYSFDFLAPEKISAAKVRSVLEAFGKVASDGWSCWAFSNHDVMRPASRWAAGEA
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCC
DPVAYLKVISALLMSLRGSVCIYQGEELGLGEAELRFEDLQDPYGIRFWPEFKGRDGCRT
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCC
PMVWDGDAKNGGFSQAKPWLPVPAKHLAQAVNVQQGDQASLLEHYRRFLSFRRAHPALAK
CEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GDITFIESEGDTVAFTRRAGNEQVVCVFNLGAKPAKVDLGSRSLQPLPGHGFSGQARPGS
CCEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCE
IELGGYGAWFGRID
EEECCEEECCCCCC
>Mature Secondary Structure
MQSALKASSNPDLAIDRDWWRGAVIYQIYPRSYQDSNGDGIGDLKGIIERLPYIAALGAD
CCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCC
AIWISPFFKSPMKDFGYDVSDYCDVDPMFGTLADFDALTAEAHRLGLKVMIDEVLSHTAD
EEEECHHHHCHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IHPWFKESRSSRSNPKADWYVWADARPDGTPPNNWLSIFGGSAWQWDTSRQQYYLHNFLA
CCHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCEECCCCCHHHHHHHHHH
EQPDLNFHNREVQDALLDVTRFWLERGVDGFRLDTINFYFHSQGLENNPPLPPEERNDQT
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCC
APAVNPYNYQDHLYDKSRPENLGFLERFRALLDEYPATAAVGEVGDSQRGLEVVAAYTAG
CCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEEEECC
GKRVHMCYSFDFLAPEKISAAKVRSVLEAFGKVASDGWSCWAFSNHDVMRPASRWAAGEA
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCC
DPVAYLKVISALLMSLRGSVCIYQGEELGLGEAELRFEDLQDPYGIRFWPEFKGRDGCRT
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCC
PMVWDGDAKNGGFSQAKPWLPVPAKHLAQAVNVQQGDQASLLEHYRRFLSFRRAHPALAK
CEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GDITFIESEGDTVAFTRRAGNEQVVCVFNLGAKPAKVDLGSRSLQPLPGHGFSGQARPGS
CCEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCE
IELGGYGAWFGRID
EEECCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]