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The map label for this gene is soxB [H]

Identifier: 13473721

GI number: 13473721

Start: 3498288

End: 3499454

Strand: Reverse

Name: soxB [H]

Synonym: mll4416

Alternate gene names: 13473721

Gene position: 3499454-3498288 (Counterclockwise)

Preceding gene: 13473722

Following gene: 13473719

Centisome position: 49.74

GC content: 65.38

Gene sequence:

>1167_bases
ATGCGCTACGACATCGTCATCATCGGCGGGGCCATCGTCGGGTCCTCCATTGCCTACTATCTGCGCGAGGAAGGGTTTTC
CGGCTCGATCGCGCTGATCGAGCGCGATCCGCAATTCGCGCATGCGGCGACGACGCTGTCCATGGCCTCGATCCGCCAGC
AATTCTCGATTCCCGAAAACATCCGCCTGTCGCAGTTCACGCTGAAACTGTTCCGGCGGCTGAAGGAGACATTCGGCACC
GATGCCGATATCGGTTTCCGCGAGGGCGGCTATCTCATCCTGGCCGGCGAGAATGGCCTGCCGGTGCTCAAGGCGAACCA
TGATGCTCAGGTCGCCGAGGGCGCCGACATCGTGCTCGAGGACGCCGAGCAGCTGACGCGGCGCTTCGCCTGGCTGTCGG
CTGAGGGCATCTCCGCCGGCGCCTACGGCCGGACCGGCGAAGGCTGGTTCGACGCGCATGCGATGCTGATGCTGTTCCGC
AAGGCGCTGCGCGACAAGAAGATCGATTTCATCGCCGCCTCTGTCACCGGCATTGCGCGCGACGGCGATCGCGTCACCGG
CGTCTCGCTCGACAATGGCCAGACCTTGGAGGCCGGCATCGTCGTCAACGCCGCCGGGCCGAATGCCGGCAAGGTCGCGG
CCCTTGCCGGGCTGGCGCTGCCGGTCGAGCCGCGCAAGCGCAACGTCTTCGTCTTCGAGGCGCGCGAGAAATATGCCGAC
ATGCCGCTGCTGGTCGATCCCTCCGGCATCTACGTGCGCCCCGAAGGCTCGGTCTACCTCACCGGCGGCGCCGAACCGGA
AGAAGGCGACGGCCCGGCCGACCCCAGCGATTTCGAGGTCGACTGGCCACTGTTCGAAGAGGTGATCTGGCCGGTGCTGG
CGACCCGCATTCCGGCCTTCGAGGCAATCAAGGCGACCCGCGCATGGGCAGGGCACTATGACTACAACACGCTCGACCAG
AACGCGGTGATCGGCCCGCATCCAGAGGTCGGCAATTTCATCTTCGCCAACGGTTTTTCCGGCCACGGCCTGCAGCAGGC
GCCGGCGGTGGGCAAGGCGCTGGCCGAGTTCCTGGTGCATGGTGGATACCGGACGATCGATTGCTCGGCGTTTGGCTATG
GGCGGGTGGCGGAAGGAAGGGCGTTCCGGGAATTGAACGTGATTTGA

Upstream 100 bases:

>100_bases
ATGATGGCATGATCCGGCTGGTTGACTCCGAGCGCGGCACGCGCTTCGAGATCACACTGCCGGCGGCATAGACAGGCCGC
CGGCTCGGATCGGAGAAAAA

Downstream 100 bases:

>100_bases
GAAGCGCCTAGTCAACCGTCGCAGCGATAGCGAGAGCATTGCCGAGCGCGTGGCCGGCGGCCGTGTTGTCGAAGATGCCC
CAGACCTCGGCGCCCGAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRYDIVIIGGAIVGSSIAYYLREEGFSGSIALIERDPQFAHAATTLSMASIRQQFSIPENIRLSQFTLKLFRRLKETFGT
DADIGFREGGYLILAGENGLPVLKANHDAQVAEGADIVLEDAEQLTRRFAWLSAEGISAGAYGRTGEGWFDAHAMLMLFR
KALRDKKIDFIAASVTGIARDGDRVTGVSLDNGQTLEAGIVVNAAGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYAD
MPLLVDPSGIYVRPEGSVYLTGGAEPEEGDGPADPSDFEVDWPLFEEVIWPVLATRIPAFEAIKATRAWAGHYDYNTLDQ
NAVIGPHPEVGNFIFANGFSGHGLQQAPAVGKALAEFLVHGGYRTIDCSAFGYGRVAEGRAFRELNVI

Sequences:

>Translated_388_residues
MRYDIVIIGGAIVGSSIAYYLREEGFSGSIALIERDPQFAHAATTLSMASIRQQFSIPENIRLSQFTLKLFRRLKETFGT
DADIGFREGGYLILAGENGLPVLKANHDAQVAEGADIVLEDAEQLTRRFAWLSAEGISAGAYGRTGEGWFDAHAMLMLFR
KALRDKKIDFIAASVTGIARDGDRVTGVSLDNGQTLEAGIVVNAAGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYAD
MPLLVDPSGIYVRPEGSVYLTGGAEPEEGDGPADPSDFEVDWPLFEEVIWPVLATRIPAFEAIKATRAWAGHYDYNTLDQ
NAVIGPHPEVGNFIFANGFSGHGLQQAPAVGKALAEFLVHGGYRTIDCSAFGYGRVAEGRAFRELNVI
>Mature_388_residues
MRYDIVIIGGAIVGSSIAYYLREEGFSGSIALIERDPQFAHAATTLSMASIRQQFSIPENIRLSQFTLKLFRRLKETFGT
DADIGFREGGYLILAGENGLPVLKANHDAQVAEGADIVLEDAEQLTRRFAWLSAEGISAGAYGRTGEGWFDAHAMLMLFR
KALRDKKIDFIAASVTGIARDGDRVTGVSLDNGQTLEAGIVVNAAGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYAD
MPLLVDPSGIYVRPEGSVYLTGGAEPEEGDGPADPSDFEVDWPLFEEVIWPVLATRIPAFEAIKATRAWAGHYDYNTLDQ
NAVIGPHPEVGNFIFANGFSGHGLQQAPAVGKALAEFLVHGGYRTIDCSAFGYGRVAEGRAFRELNVI

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI8923708, Length=412, Percent_Identity=40.7766990291262, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI24797151, Length=383, Percent_Identity=27.154046997389, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI197927446, Length=374, Percent_Identity=25.9358288770053, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI21361378, Length=374, Percent_Identity=25.9358288770053, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI194306651, Length=370, Percent_Identity=23.5135135135135, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541536, Length=427, Percent_Identity=31.1475409836066, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI20129729, Length=409, Percent_Identity=39.3643031784841, Blast_Score=268, Evalue=4e-72,
Organism=Drosophila melanogaster, GI17985989, Length=405, Percent_Identity=33.0864197530864, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI20130091, Length=384, Percent_Identity=25.2604166666667, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 41941; Mature: 41941

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYDIVIIGGAIVGSSIAYYLREEGFSGSIALIERDPQFAHAATTLSMASIRQQFSIPEN
CEEEEEEECCHHHHHHHEEEHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCC
IRLSQFTLKLFRRLKETFGTDADIGFREGGYLILAGENGLPVLKANHDAQVAEGADIVLE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCEEEH
DAEQLTRRFAWLSAEGISAGAYGRTGEGWFDAHAMLMLFRKALRDKKIDFIAASVTGIAR
HHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEC
DGDRVTGVSLDNGQTLEAGIVVNAAGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYAD
CCCEEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHCEECCCCCCCCCEEEEECCHHHCC
MPLLVDPSGIYVRPEGSVYLTGGAEPEEGDGPADPSDFEVDWPLFEEVIWPVLATRIPAF
CCEEECCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCHH
EAIKATRAWAGHYDYNTLDQNAVIGPHPEVGNFIFANGFSGHGLQQAPAVGKALAEFLVH
HHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
GGYRTIDCSAFGYGRVAEGRAFRELNVI
CCCEEEEECCCCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MRYDIVIIGGAIVGSSIAYYLREEGFSGSIALIERDPQFAHAATTLSMASIRQQFSIPEN
CEEEEEEECCHHHHHHHEEEHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCC
IRLSQFTLKLFRRLKETFGTDADIGFREGGYLILAGENGLPVLKANHDAQVAEGADIVLE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCEEEH
DAEQLTRRFAWLSAEGISAGAYGRTGEGWFDAHAMLMLFRKALRDKKIDFIAASVTGIAR
HHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEC
DGDRVTGVSLDNGQTLEAGIVVNAAGPNAGKVAALAGLALPVEPRKRNVFVFEAREKYAD
CCCEEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHCEECCCCCCCCCEEEEECCHHHCC
MPLLVDPSGIYVRPEGSVYLTGGAEPEEGDGPADPSDFEVDWPLFEEVIWPVLATRIPAF
CCEEECCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCHH
EAIKATRAWAGHYDYNTLDQNAVIGPHPEVGNFIFANGFSGHGLQQAPAVGKALAEFLVH
HHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
GGYRTIDCSAFGYGRVAEGRAFRELNVI
CCCEEEEECCCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]