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The map label for this gene is ffh [H]

Identifier: 13473694

GI number: 13473694

Start: 3476955

End: 3478553

Strand: Direct

Name: ffh [H]

Synonym: mlr4379

Alternate gene names: 13473694

Gene position: 3476955-3478553 (Clockwise)

Preceding gene: 13473693

Following gene: 13473695

Centisome position: 49.42

GC content: 66.6

Gene sequence:

>1599_bases
ATGTTTGAATCGCTGCAGGAGCGCCTTGGCTCCATCCTGAACGGCCTCACCGGTCGCGGCGCGCTTTCCGAGGCTGATGT
CTCGGCGGCGCTGCGCGAGGTGCGCCGTGCGCTGCTCGAGGCCGACGTGGCGCTGGAAGTGGTGCGGTCCTTCACCGACA
AGGTGCGCGAAAAGGCCGTCGGCGCCGCGGTGCTGAAGTCGATCAAGCCCGGCCAGATGGTCGTCAAGATCGTTCATGAC
GAGCTGGTCGACATGCTGGGCGCCGAGGGCGTCGCCATCGACCTCAATGCGCCGGCCCCCGTCGTTATCATGATGGTCGG
CCTGCAGGGCTCCGGCAAGACGACCACTTCGGCCAAGATTGCCAAGCGGCTGACCGAGCGCCAGAACAAGAAGGTTCTGA
TGGCCTCGCTCGACACGCGGCGGCCCGCCGCGCAGGAGCAGTTGCGCCAGCTCGGCGAGCAGACCAAGGTCGCGACGCTG
CCGATCATTGCTGGCCAGAACCCCGTCGATATCGCCAGGCGCGCCGTGCAGGCGGCCAAGCTCGGCGGCCATGACGTCGT
CATCCTCGACACCGCCGGCCGCACCCATATCGACGAGCCGCTGATGGTCGAGATGGCCGACATCAAGAAGGTGTCGAGCC
CGCACGAGATCCTGCTGGTCGCCGATTCGCTGACCGGCCAGGACGCCGTCAACCTGGCCAAAAGCTTCGACGAGCGCGTC
GGCATCACCGGCCTGGTGCTGACCCGCATGGACGGCGACGGCCGCGGCGGTGCGGCGCTTTCGATGCGCGCCGTCACCGG
CAAGCCGATCAAGCTGATCGGCACCGGCGAAAAGATGGACGGGCTGGAGGAATTCCACCCCAAGCGCATCGCCGACCGCA
TCCTCGGCATGGGCGACATCGTCTCGCTGGTCGAAAAGGCCGCCGAAAACATCGACGCCGAGCAGGCGGCGGCGATGGCC
AAGAAGATGCAGTCGGGCAAGTTCGACCTGAACGACCTCGCCCAGCAGCTTCAGCAGATGTCGAAAATGGGCGGCATGGG
CGGCATCATGGGCATGATGCCCGGCATGGGCAAGATGAAGGACCAGATGGCCGCCGCCGGCCTCGACGACAAGATGTTCG
GCCGCCAGCTCGCCATCATCTCGTCGATGACCAAGGCCGAGCGCGCCAACCCCGATATTCTCAAGCATTCGCGCAAAAAG
CGCATCGCCGCCGGCTCCGGCACCGACGCCGCCGAGATCAACAAGCTGTTGAAGATGCATCGCGGCATGGCCGACATGAT
GAAGGCGATGGGCGGCAAGGGCAAAGGCGGCGGCCTGATGCGCGGCATGATGGGCGGCCTTGCTTCCAAGATGGGTCTCG
GCGGCATGATGCCCGGCGGTATGGGAGGCATGGGCGGCATGCCCGATCTCTCCAAGATGGATCCCAAGCAGCTCGAAGCC
TTGCAGAAGCAGGCGCAGGCCGCCGGCCTCGGCGGCATGAAGGGCCTGCCCGGCGGACTTCCCGGTGGCGGCCTGCCAGG
CCTGCCCGGCGGAATGAAACTTCCGGGGCTTCCCGGCCTCGGCGGCGGCGGACTGCCGGGCCTTGGCAAGAAGAAGTGA

Upstream 100 bases:

>100_bases
CCGGGTGCTTTTTGGTTTTGGGCTTTGCTTTTGCTTGGACAGTTGGCGCGAACGCATTACCTCTCGGGCATCATCCGGGT
GCCAGGGAAAAGGAAAACGA

Downstream 100 bases:

>100_bases
GAATGCGGATGAACGAAGAAAAGGACATGGCCGACGCCCGCACCATCCTGGCCGGCTACCGCGCTTCGATCGACAACATC
GACGCCGCCCTCATCCACAT

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MFESLQERLGSILNGLTGRGALSEADVSAALREVRRALLEADVALEVVRSFTDKVREKAVGAAVLKSIKPGQMVVKIVHD
ELVDMLGAEGVAIDLNAPAPVVIMMVGLQGSGKTTTSAKIAKRLTERQNKKVLMASLDTRRPAAQEQLRQLGEQTKVATL
PIIAGQNPVDIARRAVQAAKLGGHDVVILDTAGRTHIDEPLMVEMADIKKVSSPHEILLVADSLTGQDAVNLAKSFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDGLEEFHPKRIADRILGMGDIVSLVEKAAENIDAEQAAAMA
KKMQSGKFDLNDLAQQLQQMSKMGGMGGIMGMMPGMGKMKDQMAAAGLDDKMFGRQLAIISSMTKAERANPDILKHSRKK
RIAAGSGTDAAEINKLLKMHRGMADMMKAMGGKGKGGGLMRGMMGGLASKMGLGGMMPGGMGGMGGMPDLSKMDPKQLEA
LQKQAQAAGLGGMKGLPGGLPGGGLPGLPGGMKLPGLPGLGGGGLPGLGKKK

Sequences:

>Translated_532_residues
MFESLQERLGSILNGLTGRGALSEADVSAALREVRRALLEADVALEVVRSFTDKVREKAVGAAVLKSIKPGQMVVKIVHD
ELVDMLGAEGVAIDLNAPAPVVIMMVGLQGSGKTTTSAKIAKRLTERQNKKVLMASLDTRRPAAQEQLRQLGEQTKVATL
PIIAGQNPVDIARRAVQAAKLGGHDVVILDTAGRTHIDEPLMVEMADIKKVSSPHEILLVADSLTGQDAVNLAKSFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDGLEEFHPKRIADRILGMGDIVSLVEKAAENIDAEQAAAMA
KKMQSGKFDLNDLAQQLQQMSKMGGMGGIMGMMPGMGKMKDQMAAAGLDDKMFGRQLAIISSMTKAERANPDILKHSRKK
RIAAGSGTDAAEINKLLKMHRGMADMMKAMGGKGKGGGLMRGMMGGLASKMGLGGMMPGGMGGMGGMPDLSKMDPKQLEA
LQKQAQAAGLGGMKGLPGGLPGGGLPGLPGGMKLPGLPGLGGGGLPGLGKKK
>Mature_532_residues
MFESLQERLGSILNGLTGRGALSEADVSAALREVRRALLEADVALEVVRSFTDKVREKAVGAAVLKSIKPGQMVVKIVHD
ELVDMLGAEGVAIDLNAPAPVVIMMVGLQGSGKTTTSAKIAKRLTERQNKKVLMASLDTRRPAAQEQLRQLGEQTKVATL
PIIAGQNPVDIARRAVQAAKLGGHDVVILDTAGRTHIDEPLMVEMADIKKVSSPHEILLVADSLTGQDAVNLAKSFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDGLEEFHPKRIADRILGMGDIVSLVEKAAENIDAEQAAAMA
KKMQSGKFDLNDLAQQLQQMSKMGGMGGIMGMMPGMGKMKDQMAAAGLDDKMFGRQLAIISSMTKAERANPDILKHSRKK
RIAAGSGTDAAEINKLLKMHRGMADMMKAMGGKGKGGGLMRGMMGGLASKMGLGGMMPGGMGGMGGMPDLSKMDPKQLEA
LQKQAQAAGLGGMKGLPGGLPGGGLPGLPGGMKLPGLPGLGGGGLPGLGKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=508, Percent_Identity=32.6771653543307, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI226371618, Length=440, Percent_Identity=32.9545454545455, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI295424842, Length=316, Percent_Identity=31.3291139240506, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI23308697, Length=316, Percent_Identity=31.3291139240506, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI89061728, Length=160, Percent_Identity=35, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=52.3584905660377, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1789874, Length=265, Percent_Identity=35.0943396226415, Blast_Score=145, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17539958, Length=487, Percent_Identity=29.1581108829569, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI193206261, Length=298, Percent_Identity=33.2214765100671, Blast_Score=118, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=503, Percent_Identity=33.0019880715706, Blast_Score=233, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6320498, Length=317, Percent_Identity=26.1829652996845, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17647949, Length=484, Percent_Identity=31.6115702479339, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24641198, Length=319, Percent_Identity=29.7805642633229, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 55422; Mature: 55422

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.9 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.9 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESLQERLGSILNGLTGRGALSEADVSAALREVRRALLEADVALEVVRSFTDKVREKAV
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAVLKSIKPGQMVVKIVHDELVDMLGAEGVAIDLNAPAPVVIMMVGLQGSGKTTTSAKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHH
AKRLTERQNKKVLMASLDTRRPAAQEQLRQLGEQTKVATLPIIAGQNPVDIARRAVQAAK
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHH
LGGHDVVILDTAGRTHIDEPLMVEMADIKKVSSPHEILLVADSLTGQDAVNLAKSFDERV
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDGLEEFHPKRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHCCHHHHHHHHHHHHHCCHHHH
VSLVEKAAENIDAEQAAAMAKKMQSGKFDLNDLAQQLQQMSKMGGMGGIMGMMPGMGKMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHH
DQMAAAGLDDKMFGRQLAIISSMTKAERANPDILKHSRKKRIAAGSGTDAAEINKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RGMADMMKAMGGKGKGGGLMRGMMGGLASKMGLGGMMPGGMGGMGGMPDLSKMDPKQLEA
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LQKQAQAAGLGGMKGLPGGLPGGGLPGLPGGMKLPGLPGLGGGGLPGLGKKK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFESLQERLGSILNGLTGRGALSEADVSAALREVRRALLEADVALEVVRSFTDKVREKAV
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAVLKSIKPGQMVVKIVHDELVDMLGAEGVAIDLNAPAPVVIMMVGLQGSGKTTTSAKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHH
AKRLTERQNKKVLMASLDTRRPAAQEQLRQLGEQTKVATLPIIAGQNPVDIARRAVQAAK
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHH
LGGHDVVILDTAGRTHIDEPLMVEMADIKKVSSPHEILLVADSLTGQDAVNLAKSFDERV
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDGLEEFHPKRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHCCHHHHHHHHHHHHHCCHHHH
VSLVEKAAENIDAEQAAAMAKKMQSGKFDLNDLAQQLQQMSKMGGMGGIMGMMPGMGKMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHH
DQMAAAGLDDKMFGRQLAIISSMTKAERANPDILKHSRKKRIAAGSGTDAAEINKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RGMADMMKAMGGKGKGGGLMRGMMGGLASKMGLGGMMPGGMGGMGGMPDLSKMDPKQLEA
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LQKQAQAAGLGGMKGLPGGLPGGGLPGLPGGMKLPGLPGLGGGGLPGLGKKK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA