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The map label for this gene is mltB [H]

Identifier: 13473689

GI number: 13473689

Start: 3472580

End: 3473437

Strand: Reverse

Name: mltB [H]

Synonym: mll4372

Alternate gene names: 13473689

Gene position: 3473437-3472580 (Counterclockwise)

Preceding gene: 13473698

Following gene: 13473684

Centisome position: 49.37

GC content: 63.75

Gene sequence:

>858_bases
ATGCACGTTTCGCTGGCAAATTCGCAGATGGGACGTGAATCAGGCAACCAGGAGAACAACATGGCATTTCTTGCCAAGGG
TAGGATTTTAGCGGCCGCGGTGGTGGCCGTGCTTGGGCTGGCGACGGGCGCACAGGCGGCGGCCAGCTGTGGCAGCACCG
GTGCGGGCTTCGATGCCTGGAAGCCGGGCTTCGCCGAACAGGCTAAAGCCGAAGGCGTGGGCGCCAAGGGCCTGGCCGCT
TTGGCTGGCGCCACTTACGCGACAAAGACAATTTCCGTCGACCGCGGCATTCACAAGGCGTTCAGCGGCTCGGTGGATGC
CTTCATGAAGCGCCGTGGCGGCGCGGCGATCATTTCCAAGGGCCGTTCGCTGAAAAAGGCAAACGCGGCGATGTTCAGCC
AGATCGAGAGCAATTACGGCGTGTCGCCCGGCGTATTGCTGGCCATCTGGGGCATGGAGACCGGCTTCGGTTCGTCCATG
GGCAACCAGAATACGGTCTCGGCCATTTTGACACTTGCCTATGATTGCCGCCGCCCGGAATTCTTTCACCCGCATGCCAT
TGCGGCGCTGAAGCTGGTCGATCGCGGCGCCTTGAGCGCCTCGTCGGTCGGCGCCGCGCATGGCGAAATCGGCCATACGC
AGTTCCTGCCCGGGAACGTCCTGAAATATGGCGTGGGCAGCGGCAACCTGCGCGACAAGGCCACCGCACTGGCTTCCACC
GCCAACTTCCTCAAGGCCCATGGCTGGCGGCGCGGCGCGAGCGCGGCGGACAATATCGGCGCAATTGCCGGCTGGAATGA
CGCCAGCGTCTACCAGCAGGCCATCGTGCGCATCGCCACGGCGATCGACGGCGATTGA

Upstream 100 bases:

>100_bases
ATCGACGTCTTCCATGGCAATTTCGACCCCGCCACAATAATCACTTGATCGTAGGCAAATTCCCCGGCATTCGCCAGCAT
CGTGCCGCGGACGGTGACAA

Downstream 100 bases:

>100_bases
TTGAAAACTTATCCGACAAGAGCCCGGCCATGCGCCGGGCTTTTTTGTTGGTGGAAGTCCCCTACTTCGTCATCCCTGGG
CGTAGCAGGAGCGAAGCTCC

Product: transglycolase

Products: Muramic Acid Residue [C]

Alternate protein names: 35 kDa soluble lytic transglycosylase; Murein hydrolase B; Slt35 [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MHVSLANSQMGRESGNQENNMAFLAKGRILAAAVVAVLGLATGAQAAASCGSTGAGFDAWKPGFAEQAKAEGVGAKGLAA
LAGATYATKTISVDRGIHKAFSGSVDAFMKRRGGAAIISKGRSLKKANAAMFSQIESNYGVSPGVLLAIWGMETGFGSSM
GNQNTVSAILTLAYDCRRPEFFHPHAIAALKLVDRGALSASSVGAAHGEIGHTQFLPGNVLKYGVGSGNLRDKATALAST
ANFLKAHGWRRGASAADNIGAIAGWNDASVYQQAIVRIATAIDGD

Sequences:

>Translated_285_residues
MHVSLANSQMGRESGNQENNMAFLAKGRILAAAVVAVLGLATGAQAAASCGSTGAGFDAWKPGFAEQAKAEGVGAKGLAA
LAGATYATKTISVDRGIHKAFSGSVDAFMKRRGGAAIISKGRSLKKANAAMFSQIESNYGVSPGVLLAIWGMETGFGSSM
GNQNTVSAILTLAYDCRRPEFFHPHAIAALKLVDRGALSASSVGAAHGEIGHTQFLPGNVLKYGVGSGNLRDKATALAST
ANFLKAHGWRRGASAADNIGAIAGWNDASVYQQAIVRIATAIDGD
>Mature_285_residues
MHVSLANSQMGRESGNQENNMAFLAKGRILAAAVVAVLGLATGAQAAASCGSTGAGFDAWKPGFAEQAKAEGVGAKGLAA
LAGATYATKTISVDRGIHKAFSGSVDAFMKRRGGAAIISKGRSLKKANAAMFSQIESNYGVSPGVLLAIWGMETGFGSSM
GNQNTVSAILTLAYDCRRPEFFHPHAIAALKLVDRGALSASSVGAAHGEIGHTQFLPGNVLKYGVGSGNLRDKATALAST
ANFLKAHGWRRGASAADNIGAIAGWNDASVYQQAIVRIATAIDGD

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=125, Percent_Identity=34.4, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011757 [H]

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 29125; Mature: 29125

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVSLANSQMGRESGNQENNMAFLAKGRILAAAVVAVLGLATGAQAAASCGSTGAGFDAW
CEEECCCCHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCC
KPGFAEQAKAEGVGAKGLAALAGATYATKTISVDRGIHKAFSGSVDAFMKRRGGAAIISK
CCCHHHHHHHCCCCCHHHHHHHCCHHHHEEEEHHHHHHHHHCCCHHHHHHHCCCHHHHHC
GRSLKKANAAMFSQIESNYGVSPGVLLAIWGMETGFGSSMGNQNTVSAILTLAYDCRRPE
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
FFHPHAIAALKLVDRGALSASSVGAAHGEIGHTQFLPGNVLKYGVGSGNLRDKATALAST
CCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHH
ANFLKAHGWRRGASAADNIGAIAGWNDASVYQQAIVRIATAIDGD
HHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHVSLANSQMGRESGNQENNMAFLAKGRILAAAVVAVLGLATGAQAAASCGSTGAGFDAW
CEEECCCCHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCC
KPGFAEQAKAEGVGAKGLAALAGATYATKTISVDRGIHKAFSGSVDAFMKRRGGAAIISK
CCCHHHHHHHCCCCCHHHHHHHCCHHHHEEEEHHHHHHHHHCCCHHHHHHHCCCHHHHHC
GRSLKKANAAMFSQIESNYGVSPGVLLAIWGMETGFGSSMGNQNTVSAILTLAYDCRRPE
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
FFHPHAIAALKLVDRGALSASSVGAAHGEIGHTQFLPGNVLKYGVGSGNLRDKATALAST
CCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHH
ANFLKAHGWRRGASAADNIGAIAGWNDASVYQQAIVRIATAIDGD
HHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7476170; 7789526; 9205837; 9278503; 3553176; 9761817; 10570954; 10545329; 10684641 [H]