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The map label for this gene is xerC

Identifier: 13473627

GI number: 13473627

Start: 3415632

End: 3416570

Strand: Direct

Name: xerC

Synonym: mlr4290

Alternate gene names: 13473627

Gene position: 3415632-3416570 (Clockwise)

Preceding gene: 13473624

Following gene: 13473628

Centisome position: 48.54

GC content: 68.9

Gene sequence:

>939_bases
ATGCAGGAATTCCTCATCCCGGCGAAACCCGATCTCCAGGCGGCGCGTGAAAGCTGGCTGAAGATGCTCGCGCGTGAACG
TCGCCTATCACCCGAGACAGTGGAAGCCTATGAGCGCGACACGCGCCAGTTCCTGCATTTCCTCACCGGCCATTGCGGCG
GCTCGCCCGGCATTTCCGACATCGCCAATCTGCGCCCGGCCGATCTGCGCGGCTTCCTCGCCGCCCGCCGCAACGCCGGC
GCCGGCGCCCGCACGCTGGGCCGAGGTCTCGCCGGCATCCGTTCGCTGCTGCGGTTCCTCGAACGCCGTGGCCTGGTCAA
CGCCGCTGGCGCCGCCGCGTTGCGCGCGCCGCGCCAGCCCAAATCGCTGCCAAAACCGCTGACGGCGAGCGACGCCAAAC
AGGTCGTGTCGGTGGAAGGCCAGCTGGCCGAAGAGCCCTGGATCGCCGCCCGCAACGCCGCCGTGCTGACGCTGCTCTAC
GGCTCGGGCCTGCGCATTTCCGAAGCGCTCGGCCTCGCCGGCGCCGATCTGGCCTCGGAGACCGACACCGTGCTTCGCGT
CACCGGCAAGGGCGGCAAGACGCGGCTGGTGCCGGTGCTGCCGGTGGCGCTGCGGGCAATCGCCGAATATCGCCGGCTCT
GCCCCTATCATCTCGATCCGAAAGGCCTGTTGTTTCGCGGCGCGCGCGGCGGCCCGCTCAACCCGGCCATCATCCAGCGC
GACATGGCCAAACTGCGCTCGGCGCTCAACCTGCCCGACACCGCGACCCCGCATGCGCTGCGCCACTCCTTCGCCACCCA
TTTGCTTGGCCGCGGCGGTGATCTGCGCACCATCCAGGAACTGCTCGGCCACGCCAGCCTGTCGACGACGCAAATCTACA
CCGGCGTCGACACCGCAAGGCTGCTGGAAATCTACGAATCGGCCCATCCGAGGGCATAA

Upstream 100 bases:

>100_bases
TCATCGCGAATATCCTTTGGCCTGCTCTAACCCCACGCGGCCATCATTTCAATGACGGGCTCTTCACCGCTTCCTAACCC
GGATACAAGAAAATGCCGCC

Downstream 100 bases:

>100_bases
ACCCTTCAATTTCGCGGTACCAGTTAACCGTTTTGCCGCTTTTCAGTCCTAGGAATGGGATCATGAAACGCGTCATTGCC
ATCGCCGACCGTGCAGCTTC

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MQEFLIPAKPDLQAARESWLKMLARERRLSPETVEAYERDTRQFLHFLTGHCGGSPGISDIANLRPADLRGFLAARRNAG
AGARTLGRGLAGIRSLLRFLERRGLVNAAGAAALRAPRQPKSLPKPLTASDAKQVVSVEGQLAEEPWIAARNAAVLTLLY
GSGLRISEALGLAGADLASETDTVLRVTGKGGKTRLVPVLPVALRAIAEYRRLCPYHLDPKGLLFRGARGGPLNPAIIQR
DMAKLRSALNLPDTATPHALRHSFATHLLGRGGDLRTIQELLGHASLSTTQIYTGVDTARLLEIYESAHPRA

Sequences:

>Translated_312_residues
MQEFLIPAKPDLQAARESWLKMLARERRLSPETVEAYERDTRQFLHFLTGHCGGSPGISDIANLRPADLRGFLAARRNAG
AGARTLGRGLAGIRSLLRFLERRGLVNAAGAAALRAPRQPKSLPKPLTASDAKQVVSVEGQLAEEPWIAARNAAVLTLLY
GSGLRISEALGLAGADLASETDTVLRVTGKGGKTRLVPVLPVALRAIAEYRRLCPYHLDPKGLLFRGARGGPLNPAIIQR
DMAKLRSALNLPDTATPHALRHSFATHLLGRGGDLRTIQELLGHASLSTTQIYTGVDTARLLEIYESAHPRA
>Mature_312_residues
MQEFLIPAKPDLQAARESWLKMLARERRLSPETVEAYERDTRQFLHFLTGHCGGSPGISDIANLRPADLRGFLAARRNAG
AGARTLGRGLAGIRSLLRFLERRGLVNAAGAAALRAPRQPKSLPKPLTASDAKQVVSVEGQLAEEPWIAARNAAVLTLLY
GSGLRISEALGLAGADLASETDTVLRVTGKGGKTRLVPVLPVALRAIAEYRRLCPYHLDPKGLLFRGARGGPLNPAIIQR
DMAKLRSALNLPDTATPHALRHSFATHLLGRGGDLRTIQELLGHASLSTTQIYTGVDTARLLEIYESAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=302, Percent_Identity=35.4304635761589, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1789261, Length=309, Percent_Identity=36.2459546925566, Blast_Score=154, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_RHILO (Q98ED9)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105195.1
- ProteinModelPortal:   Q98ED9
- SMR:   Q98ED9
- GeneID:   1227856
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr4290
- NMPDR:   fig|266835.1.peg.3299
- HOGENOM:   HBG727654
- OMA:   QFLFFLC
- ProtClustDB:   PRK00236
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 33665; Mature: 33665

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: NA

Important sites: ACT_SITE 165-165 ACT_SITE 190-190 ACT_SITE 258-258 ACT_SITE 261-261 ACT_SITE 284-284 ACT_SITE 293-293

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEFLIPAKPDLQAARESWLKMLARERRLSPETVEAYERDTRQFLHFLTGHCGGSPGISD
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
IANLRPADLRGFLAARRNAGAGARTLGRGLAGIRSLLRFLERRGLVNAAGAAALRAPRQP
HHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCC
KSLPKPLTASDAKQVVSVEGQLAEEPWIAARNAAVLTLLYGSGLRISEALGLAGADLASE
CCCCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCC
TDTVLRVTGKGGKTRLVPVLPVALRAIAEYRRLCPYHLDPKGLLFRGARGGPLNPAIIQR
CCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHH
DMAKLRSALNLPDTATPHALRHSFATHLLGRGGDLRTIQELLGHASLSTTQIYTGVDTAR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHEECCCHHHH
LLEIYESAHPRA
HHHHHHHCCCCC
>Mature Secondary Structure
MQEFLIPAKPDLQAARESWLKMLARERRLSPETVEAYERDTRQFLHFLTGHCGGSPGISD
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
IANLRPADLRGFLAARRNAGAGARTLGRGLAGIRSLLRFLERRGLVNAAGAAALRAPRQP
HHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCC
KSLPKPLTASDAKQVVSVEGQLAEEPWIAARNAAVLTLLYGSGLRISEALGLAGADLASE
CCCCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCC
TDTVLRVTGKGGKTRLVPVLPVALRAIAEYRRLCPYHLDPKGLLFRGARGGPLNPAIIQR
CCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHH
DMAKLRSALNLPDTATPHALRHSFATHLLGRGGDLRTIQELLGHASLSTTQIYTGVDTAR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHEECCCHHHH
LLEIYESAHPRA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968