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The map label for this gene is ubiH [C]

Identifier: 13473597

GI number: 13473597

Start: 3390967

End: 3392226

Strand: Direct

Name: ubiH [C]

Synonym: mlr4251

Alternate gene names: 13473597

Gene position: 3390967-3392226 (Clockwise)

Preceding gene: 13473589

Following gene: 13473601

Centisome position: 48.19

GC content: 67.38

Gene sequence:

>1260_bases
ATGGAACGCAAGGCGGACGCCAAGACCATATCCGGGCTCGATGTTCTCGTCGCCGGCGCCGGCTATGTCGGCCTGGCCAC
CGCCGTCTCGCTGAAACAGGCGCGACCCCATCTGGCCGTGGCGCTGGTCGACGCCGCGCCCGCCGGCGCCTGGCAACGCG
ACGGCCGCGCCTCGGCCATTGCCGCTGCCGCTTGCCGCATGCTCGACCAGCTCGGTGTCTGGGCCGAGATCGCGCCACAG
GCGCAGGCGATCACCGAGATGATCATCACCGATTCGCGCAGCGCCGATCCAGTGCGCCCGGTCTTCCTGACCTTTGGCGG
CGAAGTCGCGCCGGGCGAGCCCTTCGCCCATATGGTCGCCAACAAGTCGCTCAACGGCGCCTTGCGCGCCAGAGCTGAAA
AACTCGGCATCGACATCATCGAAGGCGTCGCCGTGCAGAGTTTCGAGACCAATGGCGCCGGCATCACGGTTCATCTGGCC
GATGGGGCGGCGCTGACGGCACGGCTGCTGGTCGCCGCCGACGGCGTCAATTCGAAGCTGCGCGACATGGCCGGCATCAA
GACGGTGAAGTGGGACTATGGCCAGTCCGGCATCGTCTGCACCGTGGCGCATGAACGCCCGCACAATGGCCGCGCCGAAG
AGCACTTTTTGCCGGCCGGCCCCTTCGCCACGCTGCCGCTGAAACCCGAGGAGGACGGCACAAACCGCTCGTCGATCGTC
TGGGTCGAACGCGCGGAAGATGCCAAAGCGCTGGTGGAAGGCGACGACCTAGTCTTCGAGCATGAACTCGAACAGCGTTT
CGGCCTGAAGCTCGGCGAAATCCGCGTCGCCGACAAGCCGCGCGCCTGGCCGCTCGGCCTCACCATCGCGCGCGCCTTCG
TGGCGCCGCGCGTGGCGCTTGCCGGCGACGCCGCCCACGGCATCCATCCGATCGCCGGCCAGGGCCTCAATCTCGGCTTC
AAGGATGTGGCAGCACTCGCCGAAGTGATCGTCGAGGCCGACCGGCTCGGCCAGGACATCGGCGCGCTCGACGTGCTCGA
ACGCTACCAGCAATGGCGCCGCTTCGACACGGTACAGATGGGCATCACGACGGATGTGCTGAACCGGCTGTTTTCCAACG
ACATCACCCCGCTGCGCACCGTCCGCGACATCGGCCTCGGCCTCGTCGAACGCATGCCGCGCCTGAAGGAGTTTTTCATC
CGCCAGGCGTCGGGGTTATCCGCCGGCACGCCGAGGCTGCTGAAAGGCGAGGCGATCTGA

Upstream 100 bases:

>100_bases
TGTTTTGTGACCTCGCCGCAAAATTGCTATGGCGGTTTCCGACAGGAAGAACGAGCCGTCAAGGGCGCAGGTCCGGGCCG
GCGCGCAAGGAGCCAAGACA

Downstream 100 bases:

>100_bases
GCGCCTCACTGGCGCACCCAACGAAGCGATGGTCGTTTCCGCCAATCGCCAGGTGTGCGATCAGTTGACCTCGAAGCCCA
GCTTCTGCCGCAGCCGCAGC

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MERKADAKTISGLDVLVAGAGYVGLATAVSLKQARPHLAVALVDAAPAGAWQRDGRASAIAAAACRMLDQLGVWAEIAPQ
AQAITEMIITDSRSADPVRPVFLTFGGEVAPGEPFAHMVANKSLNGALRARAEKLGIDIIEGVAVQSFETNGAGITVHLA
DGAALTARLLVAADGVNSKLRDMAGIKTVKWDYGQSGIVCTVAHERPHNGRAEEHFLPAGPFATLPLKPEEDGTNRSSIV
WVERAEDAKALVEGDDLVFEHELEQRFGLKLGEIRVADKPRAWPLGLTIARAFVAPRVALAGDAAHGIHPIAGQGLNLGF
KDVAALAEVIVEADRLGQDIGALDVLERYQQWRRFDTVQMGITTDVLNRLFSNDITPLRTVRDIGLGLVERMPRLKEFFI
RQASGLSAGTPRLLKGEAI

Sequences:

>Translated_419_residues
MERKADAKTISGLDVLVAGAGYVGLATAVSLKQARPHLAVALVDAAPAGAWQRDGRASAIAAAACRMLDQLGVWAEIAPQ
AQAITEMIITDSRSADPVRPVFLTFGGEVAPGEPFAHMVANKSLNGALRARAEKLGIDIIEGVAVQSFETNGAGITVHLA
DGAALTARLLVAADGVNSKLRDMAGIKTVKWDYGQSGIVCTVAHERPHNGRAEEHFLPAGPFATLPLKPEEDGTNRSSIV
WVERAEDAKALVEGDDLVFEHELEQRFGLKLGEIRVADKPRAWPLGLTIARAFVAPRVALAGDAAHGIHPIAGQGLNLGF
KDVAALAEVIVEADRLGQDIGALDVLERYQQWRRFDTVQMGITTDVLNRLFSNDITPLRTVRDIGLGLVERMPRLKEFFI
RQASGLSAGTPRLLKGEAI
>Mature_419_residues
MERKADAKTISGLDVLVAGAGYVGLATAVSLKQARPHLAVALVDAAPAGAWQRDGRASAIAAAACRMLDQLGVWAEIAPQ
AQAITEMIITDSRSADPVRPVFLTFGGEVAPGEPFAHMVANKSLNGALRARAEKLGIDIIEGVAVQSFETNGAGITVHLA
DGAALTARLLVAADGVNSKLRDMAGIKTVKWDYGQSGIVCTVAHERPHNGRAEEHFLPAGPFATLPLKPEEDGTNRSSIV
WVERAEDAKALVEGDDLVFEHELEQRFGLKLGEIRVADKPRAWPLGLTIARAFVAPRVALAGDAAHGIHPIAGQGLNLGF
KDVAALAEVIVEADRLGQDIGALDVLERYQQWRRFDTVQMGITTDVLNRLFSNDITPLRTVRDIGLGLVERMPRLKEFFI
RQASGLSAGTPRLLKGEAI

Specific function: Oxygenase That Introduces The Hydroxyl Group At Carbon Four Of 2-Octaprenyl-6-Methoxyphenol Resulting In The Formation Of 2-Octaprenyl-6-Methoxy-1,4-Benzoquinone. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=415, Percent_Identity=29.8795180722892, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI32967307, Length=284, Percent_Identity=35.2112676056338, Blast_Score=146, Evalue=3e-35,
Organism=Escherichia coli, GI1789274, Length=383, Percent_Identity=35.509138381201, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789273, Length=402, Percent_Identity=34.0796019900498, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786883, Length=407, Percent_Identity=32.1867321867322, Blast_Score=162, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI25146631, Length=446, Percent_Identity=29.1479820627803, Blast_Score=151, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321694, Length=469, Percent_Identity=26.865671641791, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI19920760, Length=399, Percent_Identity=27.5689223057644, Blast_Score=135, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 44748; Mature: 44748

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKADAKTISGLDVLVAGAGYVGLATAVSLKQARPHLAVALVDAAPAGAWQRDGRASAI
CCCCCCCHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHH
AAAACRMLDQLGVWAEIAPQAQAITEMIITDSRSADPVRPVFLTFGGEVAPGEPFAHMVA
HHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHH
NKSLNGALRARAEKLGIDIIEGVAVQSFETNGAGITVHLADGAALTARLLVAADGVNSKL
CCCCCHHHHHHHHHHCCHHHCCCEEEEEECCCCEEEEEEECCCHHHHHHHEEECCCCHHH
RDMAGIKTVKWDYGQSGIVCTVAHERPHNGRAEEHFLPAGPFATLPLKPEEDGTNRSSIV
HHHHCCEEEEECCCCCCEEEEEECCCCCCCCCHHCCCCCCCEEECCCCCCCCCCCCCEEE
WVERAEDAKALVEGDDLVFEHELEQRFGLKLGEIRVADKPRAWPLGLTIARAFVAPRVAL
EEEECCCCHHHCCCCCEEEHHHHHHHHCCEECEEEECCCCCCCCHHHHHHHHHHHCCCEE
AGDAAHGIHPIAGQGLNLGFKDVAALAEVIVEADRLGQDIGALDVLERYQQWRRFDTVQM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHC
GITTDVLNRLFSNDITPLRTVRDIGLGLVERMPRLKEFFIRQASGLSAGTPRLLKGEAI
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MERKADAKTISGLDVLVAGAGYVGLATAVSLKQARPHLAVALVDAAPAGAWQRDGRASAI
CCCCCCCHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHH
AAAACRMLDQLGVWAEIAPQAQAITEMIITDSRSADPVRPVFLTFGGEVAPGEPFAHMVA
HHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHH
NKSLNGALRARAEKLGIDIIEGVAVQSFETNGAGITVHLADGAALTARLLVAADGVNSKL
CCCCCHHHHHHHHHHCCHHHCCCEEEEEECCCCEEEEEEECCCHHHHHHHEEECCCCHHH
RDMAGIKTVKWDYGQSGIVCTVAHERPHNGRAEEHFLPAGPFATLPLKPEEDGTNRSSIV
HHHHCCEEEEECCCCCCEEEEEECCCCCCCCCHHCCCCCCCEEECCCCCCCCCCCCCEEE
WVERAEDAKALVEGDDLVFEHELEQRFGLKLGEIRVADKPRAWPLGLTIARAFVAPRVAL
EEEECCCCHHHCCCCCEEEHHHHHHHHCCEECEEEECCCCCCCCHHHHHHHHHHHCCCEE
AGDAAHGIHPIAGQGLNLGFKDVAALAEVIVEADRLGQDIGALDVLERYQQWRRFDTVQM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHC
GITTDVLNRLFSNDITPLRTVRDIGLGLVERMPRLKEFFIRQASGLSAGTPRLLKGEAI
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]