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The map label for this gene is groES

Identifier: 13472059

GI number: 13472059

Start: 1801087

End: 1801401

Strand: Reverse

Name: groES

Synonym: mll2233

Alternate gene names: 13472059

Gene position: 1801401-1801087 (Counterclockwise)

Preceding gene: 13472062

Following gene: 13472058

Centisome position: 25.6

GC content: 61.27

Gene sequence:

>315_bases
ATGAAGTTTCGGCCACTCCACGACCGCGTCGTCATCCGGCGCGCCGAAGGCGATACCAAATCCAAGGGCGGCATCATCAT
TCCCGACAACGCCAAGGAAAAGCCGCAGGAAGGCGAAGTTATCGCCGTCGGCCCCGGCGCACGCGACGAAAACGGCGCGC
TTGTGCCGCTCGACGTAAAGGCCGGCGACCTGATCCTGTTCGGCAAATGGTCGGGCACCGAGGTCAAGATCGACGGCGAG
GACCTTCTGATCATGAAGGAAGCCGACATTATGGGCGTCATCGACAAGAGCGTCGAAGCCAAGAAGGCCGCCTGA

Upstream 100 bases:

>100_bases
ATCGAGACCGCGAATAATTTTTGGCACTCCTATCTATCGAGTGCCAAAGCGCCTATATGGGGGAAGCGGCCGCCTAAGCC
GGCCCCAGAAAGAAGTTTTC

Downstream 100 bases:

>100_bases
CTGGAGCGCCGCGCCTTCCGCGCGGGGTTCGTCCACTCCAAATTCGAACGGGATTGAAAAAATGTCTGCCAAGGAAATCA
AATTCGCCACCGACGCGCGT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein 1; Protein Cpn10 1

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MKFRPLHDRVVIRRAEGDTKSKGGIIIPDNAKEKPQEGEVIAVGPGARDENGALVPLDVKAGDLILFGKWSGTEVKIDGE
DLLIMKEADIMGVIDKSVEAKKAA

Sequences:

>Translated_104_residues
MKFRPLHDRVVIRRAEGDTKSKGGIIIPDNAKEKPQEGEVIAVGPGARDENGALVPLDVKAGDLILFGKWSGTEVKIDGE
DLLIMKEADIMGVIDKSVEAKKAA
>Mature_104_residues
MKFRPLHDRVVIRRAEGDTKSKGGIIIPDNAKEKPQEGEVIAVGPGARDENGALVPLDVKAGDLILFGKWSGTEVKIDGE
DLLIMKEADIMGVIDKSVEAKKAA

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=38.4615384615385, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=48.9583333333333, Blast_Score=96, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=40.8602150537634, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324594, Length=93, Percent_Identity=36.5591397849462, Blast_Score=68, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=42.2680412371134, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358317, Length=92, Percent_Identity=40.2173913043478, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH101_RHILO (Q98IV4)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103626.1
- ProteinModelPortal:   Q98IV4
- SMR:   Q98IV4
- GeneID:   1226287
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll2233
- NMPDR:   fig|266835.1.peg.1730
- HOGENOM:   HBG703377
- OMA:   MKFRSLH
- ProtClustDB:   PRK00364
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 11178; Mature: 11178

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRPLHDRVVIRRAEGDTKSKGGIIIPDNAKEKPQEGEVIAVGPGARDENGALVPLDVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECC
AGDLILFGKWSGTEVKIDGEDLLIMKEADIMGVIDKSVEAKKAA
CCCEEEEECCCCCEEEECCCCEEEEECCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MKFRPLHDRVVIRRAEGDTKSKGGIIIPDNAKEKPQEGEVIAVGPGARDENGALVPLDVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECC
AGDLILFGKWSGTEVKIDGEDLLIMKEADIMGVIDKSVEAKKAA
CCCEEEEECCCCCEEEECCCCEEEEECCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968