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The map label for this gene is kdgR [H]

Identifier: 13471957

GI number: 13471957

Start: 1715594

End: 1716628

Strand: Reverse

Name: kdgR [H]

Synonym: mll2094

Alternate gene names: 13471957

Gene position: 1716628-1715594 (Counterclockwise)

Preceding gene: 13471960

Following gene: 13471954

Centisome position: 24.4

GC content: 67.83

Gene sequence:

>1035_bases
ATGGCGCAAGATCAGCAGCGGCGTCCGTCGATCCACGACGTGGCGAGCCGCGCCGGCGTGTCGGCCGCCACCGTCTCCAA
GGTCATGGCCGGCGTCGCCACGGTCAAGCCCGAGAATGCGCAGCGCGTCTTAGATGCCATTGAACAGCTCGGTTACCGCG
TCGATCCGCTGGCCTCCGACATGCGCCGGGCCAAGCGCCGCATCATCGGCGCCATCATGCCGGAATTCGAAAGCGAGTTC
TTCGGCCAGATGGTCACGCAACTCGAAAGCCTCGCCGAACAGCGGGGCTACACGCTGGTGGCGGCGTCGAGCCGCGAATC
CGAAGCGCGCGAAACGGAAATCCTCGCCCGCATGCATGACTGGCGGGTGGCAGGCGTGGTGCTGGCGCCGGTGCGCAACG
AGCATGGCCCGGCGGCCGCCTTCATGAAGGCCAACGGCATGACCGGCGTGCTGATCGACCGCGTGCTGTCGGACGACGCC
TTCGACACGGTGTCGGCCGACAGTGCGGCGGCCAGCGCCGAAGTGGCGCGCGAACTGATCGGCAAGGGCCATCGTCACAT
CCTTGTCGTCGGCCTTGGCGAGCAGGCTGCCACGGTACGCGCCCGCCTCGACGGGTTCCGCACCACCGCGCTGCACCTGG
CGCCGGACGTGCGCATCGATGTCGTGCTTGCCGAAACCGATGTCGAGCCGCTCAGGGCGCAGCTGCGCGACTATTTTGCG
AAAGGCGAGCGGCCGACGGCCGTCTATTCGCTGTTCCTCAAGGGCACGCTGGTGGCGCTGTCGGAGTTCCGGCGGCGCGG
CTGGCACTGCCCCGATGACATTTCGCTGGTCGGCTTCGACGACGCCGAATGGATGCAGGTGACATGGCCGGCCATTGCCG
CCGTGGTGCAACCGGTGCACCAGATCGCCGGCCACGCCATGGAGGCGCTGTTTGCCCGGATTGAAGGCGAGGAGGGGCCG
CCGAGAGCGCGGCTCGAACCTTGCCGGGTCTTGATGCGGGAATCCGTTGGCTCGCCAGGCAACGGCCAATCCTGA

Upstream 100 bases:

>100_bases
CTAAAATACCGCCGATGAACCGATTTACAACTGCGAAAAATCGATTTACTCGTTTCTGCGACGGACAGAAAATGCCTCTG
TCCGCGCCTCGGGAGGAGCA

Downstream 100 bases:

>100_bases
GAGCCCGCGACTGCCACCGTCCGCCAGCCACCGCAATCACAAGGCTGGCGCGCTTCCCTTCTCCCTGAAGGGAGAAGAAG
GGAACACGCCTCTGCCTTCA

Product: transcription regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MAQDQQRRPSIHDVASRAGVSAATVSKVMAGVATVKPENAQRVLDAIEQLGYRVDPLASDMRRAKRRIIGAIMPEFESEF
FGQMVTQLESLAEQRGYTLVAASSRESEARETEILARMHDWRVAGVVLAPVRNEHGPAAAFMKANGMTGVLIDRVLSDDA
FDTVSADSAAASAEVARELIGKGHRHILVVGLGEQAATVRARLDGFRTTALHLAPDVRIDVVLAETDVEPLRAQLRDYFA
KGERPTAVYSLFLKGTLVALSEFRRRGWHCPDDISLVGFDDAEWMQVTWPAIAAVVQPVHQIAGHAMEALFARIEGEEGP
PRARLEPCRVLMRESVGSPGNGQS

Sequences:

>Translated_344_residues
MAQDQQRRPSIHDVASRAGVSAATVSKVMAGVATVKPENAQRVLDAIEQLGYRVDPLASDMRRAKRRIIGAIMPEFESEF
FGQMVTQLESLAEQRGYTLVAASSRESEARETEILARMHDWRVAGVVLAPVRNEHGPAAAFMKANGMTGVLIDRVLSDDA
FDTVSADSAAASAEVARELIGKGHRHILVVGLGEQAATVRARLDGFRTTALHLAPDVRIDVVLAETDVEPLRAQLRDYFA
KGERPTAVYSLFLKGTLVALSEFRRRGWHCPDDISLVGFDDAEWMQVTWPAIAAVVQPVHQIAGHAMEALFARIEGEEGP
PRARLEPCRVLMRESVGSPGNGQS
>Mature_343_residues
AQDQQRRPSIHDVASRAGVSAATVSKVMAGVATVKPENAQRVLDAIEQLGYRVDPLASDMRRAKRRIIGAIMPEFESEFF
GQMVTQLESLAEQRGYTLVAASSRESEARETEILARMHDWRVAGVVLAPVRNEHGPAAAFMKANGMTGVLIDRVLSDDAF
DTVSADSAAASAEVARELIGKGHRHILVVGLGEQAATVRARLDGFRTTALHLAPDVRIDVVLAETDVEPLRAQLRDYFAK
GERPTAVYSLFLKGTLVALSEFRRRGWHCPDDISLVGFDDAEWMQVTWPAIAAVVQPVHQIAGHAMEALFARIEGEEGPP
RARLEPCRVLMRESVGSPGNGQS

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=338, Percent_Identity=24.2603550295858, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI48994940, Length=326, Percent_Identity=25.4601226993865, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787948, Length=334, Percent_Identity=27.2455089820359, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789068, Length=332, Percent_Identity=24.0963855421687, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790194, Length=307, Percent_Identity=24.4299674267101, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789202, Length=333, Percent_Identity=25.5255255255255, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788474, Length=343, Percent_Identity=25.6559766763848, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787906, Length=347, Percent_Identity=24.7838616714697, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786268, Length=338, Percent_Identity=23.6686390532544, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790715, Length=316, Percent_Identity=21.2025316455696, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=22.6006191950464, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37509; Mature: 37378

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQDQQRRPSIHDVASRAGVSAATVSKVMAGVATVKPENAQRVLDAIEQLGYRVDPLASD
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHH
MRRAKRRIIGAIMPEFESEFFGQMVTQLESLAEQRGYTLVAASSRESEARETEILARMHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHC
WRVAGVVLAPVRNEHGPAAAFMKANGMTGVLIDRVLSDDAFDTVSADSAAASAEVARELI
CEEEEEEEECCCCCCCCHHHEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
GKGHRHILVVGLGEQAATVRARLDGFRTTALHLAPDVRIDVVLAETDVEPLRAQLRDYFA
CCCCCEEEEEECCCHHHHHHHHHCCHHHHHEEECCCCEEEEEEECCCHHHHHHHHHHHHH
KGERPTAVYSLFLKGTLVALSEFRRRGWHCPDDISLVGFDDAEWMQVTWPAIAAVVQPVH
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHH
QIAGHAMEALFARIEGEEGPPRARLEPCRVLMRESVGSPGNGQS
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AQDQQRRPSIHDVASRAGVSAATVSKVMAGVATVKPENAQRVLDAIEQLGYRVDPLASD
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHH
MRRAKRRIIGAIMPEFESEFFGQMVTQLESLAEQRGYTLVAASSRESEARETEILARMHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHC
WRVAGVVLAPVRNEHGPAAAFMKANGMTGVLIDRVLSDDAFDTVSADSAAASAEVARELI
CEEEEEEEECCCCCCCCHHHEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
GKGHRHILVVGLGEQAATVRARLDGFRTTALHLAPDVRIDVVLAETDVEPLRAQLRDYFA
CCCCCEEEEEECCCHHHHHHHHHCCHHHHHEEECCCCEEEEEEECCCHHHHHHHHHHHHH
KGERPTAVYSLFLKGTLVALSEFRRRGWHCPDDISLVGFDDAEWMQVTWPAIAAVVQPVH
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHH
QIAGHAMEALFARIEGEEGPPRARLEPCRVLMRESVGSPGNGQS
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]