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The map label for this gene is kamA [H]

Identifier: 13471862

GI number: 13471862

Start: 1621403

End: 1622506

Strand: Reverse

Name: kamA [H]

Synonym: mll1971

Alternate gene names: 13471862

Gene position: 1622506-1621403 (Counterclockwise)

Preceding gene: 13471863

Following gene: 13471858

Centisome position: 23.06

GC content: 67.84

Gene sequence:

>1104_bases
ATGACCGACCTCAAAGATGCAACCCGCGCCGCCCCCGACACCACCTGGCAGGACGATGTCCGCCAGGGCGTGCGGCATGT
GCGCGATCTCGACCGCCTGCCGCTGTCGCCGGTCGAGCGCGCCGCCGCCCAAGCTGCTGCCGCGCACCACAAGGTGCGTG
CGCCAAAAGCCTATCTCGACCTGATCGACTGGAACGACCCGGCCGATCCGATCCGCGCGCAGGTCATCCCGTCGCCGGAC
GAATTGGAGGAGGCGGAGGGCGAGCTGGGCGATCCGATCGCCGACCATGACTTCAGCCCGGTGCCGCGACTGACGCATCG
CCATACCGACCGGGTGCTGCTGTTCCCGACCTATCAATGCGCGGTCTATTGCCGGTTCTGCTTCCGCAAGGAATCGCTGA
CCTCGATCGGCCGCGGCTATACGCGCGAGGCGCTCGAGCCGGCGCTGGCCTATATCGCGGATCATCCTGAGATCCGCGAG
GTGATCCTGACCGGCGGCGACCCGCTCTCGCTGCCCGACAAGGCGCTGGCCGAAATCGTCGCGCGCATCGAGGCGATCCC
GCATGTGCGGCTGCTGCGCATCCACACCCGCGTGCCAGTCGCGCTGCCGTCGCGCATCACATCCGGGCTGGTCGCCGCGC
TGCAGGGCCGGCTGATGGTGACCGTCGTCACGCATTTCAACCACGCGCGGGAGATCACGCCCGCGACCGAGGTGGCGTGC
CGCACCATGCGGCAGGCGGGCTTCGTGCTGCTCAACCAGAGCGTTCTGCTCAAGGGCGTCAACGATACGGTCGAGGTATT
GGAGGAGCTCTGCCGCGAGCTGATGTACCGGCTGGGAGTAAAACCCTATTACCTGCACCACGGCGACCTCGCGCGCGGCA
TGGCGCATCGGCGCACCACGATCGCGCAAGGCCAGGCGCTGGTGGAAGCGCTGAGGGCGCGCCTGTCCGGCATCTGCAAT
CCCGTCTATGTGCTCGACTTGCCGGAAGGCGGCGGCAAGGTGCCGCTCGGGCCGTGTCCTATCGAGGGCCGCGAAGGGGA
CACCTGGCGGATACGCGGCCAGGACGGCGCGATGAGGACCTATCGGGAGATTGTGGGCGAATAG

Upstream 100 bases:

>100_bases
CGGTGCTCTACGGGCGCGGCTTGCGCCGTTGGCTTCCAGTGACGGTTGACCGCGTCGTCCATCCGGTCGATAGGTCCGCG
CGACCACTCCGAGACCTGCC

Downstream 100 bases:

>100_bases
GCTGCGCTATTTGCCGACAAACGCCAACACGACCACACGCGGGGCGATGCAGTAGGCGAGGCTGACCTTGCGGCCGGTCT
TCGTCGTCGCGCGGCCGGCA

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTDLKDATRAAPDTTWQDDVRQGVRHVRDLDRLPLSPVERAAAQAAAAHHKVRAPKAYLDLIDWNDPADPIRAQVIPSPD
ELEEAEGELGDPIADHDFSPVPRLTHRHTDRVLLFPTYQCAVYCRFCFRKESLTSIGRGYTREALEPALAYIADHPEIRE
VILTGGDPLSLPDKALAEIVARIEAIPHVRLLRIHTRVPVALPSRITSGLVAALQGRLMVTVVTHFNHAREITPATEVAC
RTMRQAGFVLLNQSVLLKGVNDTVEVLEELCRELMYRLGVKPYYLHHGDLARGMAHRRTTIAQGQALVEALRARLSGICN
PVYVLDLPEGGGKVPLGPCPIEGREGDTWRIRGQDGAMRTYREIVGE

Sequences:

>Translated_367_residues
MTDLKDATRAAPDTTWQDDVRQGVRHVRDLDRLPLSPVERAAAQAAAAHHKVRAPKAYLDLIDWNDPADPIRAQVIPSPD
ELEEAEGELGDPIADHDFSPVPRLTHRHTDRVLLFPTYQCAVYCRFCFRKESLTSIGRGYTREALEPALAYIADHPEIRE
VILTGGDPLSLPDKALAEIVARIEAIPHVRLLRIHTRVPVALPSRITSGLVAALQGRLMVTVVTHFNHAREITPATEVAC
RTMRQAGFVLLNQSVLLKGVNDTVEVLEELCRELMYRLGVKPYYLHHGDLARGMAHRRTTIAQGQALVEALRARLSGICN
PVYVLDLPEGGGKVPLGPCPIEGREGDTWRIRGQDGAMRTYREIVGE
>Mature_366_residues
TDLKDATRAAPDTTWQDDVRQGVRHVRDLDRLPLSPVERAAAQAAAAHHKVRAPKAYLDLIDWNDPADPIRAQVIPSPDE
LEEAEGELGDPIADHDFSPVPRLTHRHTDRVLLFPTYQCAVYCRFCFRKESLTSIGRGYTREALEPALAYIADHPEIREV
ILTGGDPLSLPDKALAEIVARIEAIPHVRLLRIHTRVPVALPSRITSGLVAALQGRLMVTVVTHFNHAREITPATEVACR
TMRQAGFVLLNQSVLLKGVNDTVEVLEELCRELMYRLGVKPYYLHHGDLARGMAHRRTTIAQGQALVEALRARLSGICNP
VYVLDLPEGGGKVPLGPCPIEGREGDTWRIRGQDGAMRTYREIVGE

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=296, Percent_Identity=37.1621621621622, Blast_Score=194, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 40764; Mature: 40633

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLKDATRAAPDTTWQDDVRQGVRHVRDLDRLPLSPVERAAAQAAAAHHKVRAPKAYLD
CCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHE
LIDWNDPADPIRAQVIPSPDELEEAEGELGDPIADHDFSPVPRLTHRHTDRVLLFPTYQC
EECCCCCCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEHHHH
AVYCRFCFRKESLTSIGRGYTREALEPALAYIADHPEIREVILTGGDPLSLPDKALAEIV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHEEECCCCCCCCHHHHHHHH
ARIEAIPHVRLLRIHTRVPVALPSRITSGLVAALQGRLMVTVVTHFNHAREITPATEVAC
HHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCHHHHHHH
RTMRQAGFVLLNQSVLLKGVNDTVEVLEELCRELMYRLGVKPYYLHHGDLARGMAHRRTT
HHHHHCCCEEECCHHHEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHH
IAQGQALVEALRARLSGICNPVYVLDLPEGGGKVPLGPCPIEGREGDTWRIRGQDGAMRT
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHH
YREIVGE
HHHHHCC
>Mature Secondary Structure 
TDLKDATRAAPDTTWQDDVRQGVRHVRDLDRLPLSPVERAAAQAAAAHHKVRAPKAYLD
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHE
LIDWNDPADPIRAQVIPSPDELEEAEGELGDPIADHDFSPVPRLTHRHTDRVLLFPTYQC
EECCCCCCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEHHHH
AVYCRFCFRKESLTSIGRGYTREALEPALAYIADHPEIREVILTGGDPLSLPDKALAEIV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHEEECCCCCCCCHHHHHHHH
ARIEAIPHVRLLRIHTRVPVALPSRITSGLVAALQGRLMVTVVTHFNHAREITPATEVAC
HHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCHHHHHHH
RTMRQAGFVLLNQSVLLKGVNDTVEVLEELCRELMYRLGVKPYYLHHGDLARGMAHRRTT
HHHHHCCCEEECCHHHEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHH
IAQGQALVEALRARLSGICNPVYVLDLPEGGGKVPLGPCPIEGREGDTWRIRGQDGAMRT
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHH
YREIVGE
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]