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The map label for this gene is sigW [H]

Identifier: 13471781

GI number: 13471781

Start: 1538359

End: 1539255

Strand: Reverse

Name: sigW [H]

Synonym: mll1867

Alternate gene names: 13471781

Gene position: 1539255-1538359 (Counterclockwise)

Preceding gene: 13471782

Following gene: 13471779

Centisome position: 21.88

GC content: 67.0

Gene sequence:

>897_bases
ATGAGGCGCATCGAGCCGCGCCTCGATCCCGAAGGCCTTTTCGACATGCGCTACAGGGCGTTCCTGGAGACGGTCTCGCA
TTTGCGCGTCCGTCTCCACCGCTATTGCGCGCGCATGACCGGCTCGGCCCTCGACGGAGAGGACATCATGCAGGAGGCGC
TGTTCGAGGCCTATCGCAAGATCGGGCTGCTCGACGATACACAGGCGCTGCGGCCGTGGCTGTTCCGCATCGCCCATAAC
AGGTGCATCGACTTCATCCGCACCCGCCGCACGCGGCTCAAGGCCGAAGCAGGCTATGCCAGCGATGAGATCGTGCTGCC
TGTCGAGCCCGCCGGCCCGGGCGCCGGCCGCGCCATCGAAAGGCTGGTTGTGCACCTGCCGCCGAAGGAGCGCGCCTGCG
TGCTGCTCAAGGATGTCTTCGACCATTCGCTTGAGGAGATCGCCGGCCTGGTCGGCTCGACATCGGGCGGCGTCAAGTCG
GCGCTCAATCGCGGCCGGGCCAAGCTCGCCGCCTTGCCGGCGCAACCGGTCGCGGCACCCGCGCACGACCCTGAACTGGA
GCGGCTGCTCGGCCGCTATGTCGAGCTCTTCAATGCCAGGGACTGGGACGGGGTGCGGGCGCTGACCAGCGCCGACGCCC
GGCTGCGGGTTTCGGACTGCTACAATGGCCTGCTCTCCGACTCGCCCTATTTCGTCGAGTACGACCGCGGCGAGCCCTGG
CGCATGCGGCCGGACACGATCGAAGGGGAGGCCGTGCTGGTCGTCGACAGGCTGCATGGCGAGGTCTGGCGGCCAGCATA
TTTCGTGCGCATCCATGCCGACGGAGGCATCATCAACCGCATTGCCGATTATTATGCCTGCCCCTGGATCCTGGAGATGG
TGGCTGCCGACGGCTGA

Upstream 100 bases:

>100_bases
GGTCGCACTTGGTGCTTGTGGATGCGCGGCGCTTGCGCGATGCTGCGGCAAGGCTGAGCGACGCGCCGCGATGAACCAGC
AGATCCGCAATTCCCCTGAG

Downstream 100 bases:

>100_bases
TGGATTTGTCGGCAGTGCCCTGTCGCTGGGATCGGCTTTCCCGCTTATTTCACCGAGTCCGCGGCCGCCAGAATGACATC
TGCGACTTCGCGCGGTTTGG

Product: RNA polymerase sigma subunit

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MRRIEPRLDPEGLFDMRYRAFLETVSHLRVRLHRYCARMTGSALDGEDIMQEALFEAYRKIGLLDDTQALRPWLFRIAHN
RCIDFIRTRRTRLKAEAGYASDEIVLPVEPAGPGAGRAIERLVVHLPPKERACVLLKDVFDHSLEEIAGLVGSTSGGVKS
ALNRGRAKLAALPAQPVAAPAHDPELERLLGRYVELFNARDWDGVRALTSADARLRVSDCYNGLLSDSPYFVEYDRGEPW
RMRPDTIEGEAVLVVDRLHGEVWRPAYFVRIHADGGIINRIADYYACPWILEMVAADG

Sequences:

>Translated_298_residues
MRRIEPRLDPEGLFDMRYRAFLETVSHLRVRLHRYCARMTGSALDGEDIMQEALFEAYRKIGLLDDTQALRPWLFRIAHN
RCIDFIRTRRTRLKAEAGYASDEIVLPVEPAGPGAGRAIERLVVHLPPKERACVLLKDVFDHSLEEIAGLVGSTSGGVKS
ALNRGRAKLAALPAQPVAAPAHDPELERLLGRYVELFNARDWDGVRALTSADARLRVSDCYNGLLSDSPYFVEYDRGEPW
RMRPDTIEGEAVLVVDRLHGEVWRPAYFVRIHADGGIINRIADYYACPWILEMVAADG
>Mature_298_residues
MRRIEPRLDPEGLFDMRYRAFLETVSHLRVRLHRYCARMTGSALDGEDIMQEALFEAYRKIGLLDDTQALRPWLFRIAHN
RCIDFIRTRRTRLKAEAGYASDEIVLPVEPAGPGAGRAIERLVVHLPPKERACVLLKDVFDHSLEEIAGLVGSTSGGVKS
ALNRGRAKLAALPAQPVAAPAHDPELERLLGRYVELFNARDWDGVRALTSADARLRVSDCYNGLLSDSPYFVEYDRGEPW
RMRPDTIEGEAVLVVDRLHGEVWRPAYFVRIHADGGIINRIADYYACPWILEMVAADG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 33635; Mature: 33635

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIEPRLDPEGLFDMRYRAFLETVSHLRVRLHRYCARMTGSALDGEDIMQEALFEAYRK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IGLLDDTQALRPWLFRIAHNRCIDFIRTRRTRLKAEAGYASDEIVLPVEPAGPGAGRAIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHH
RLVVHLPPKERACVLLKDVFDHSLEEIAGLVGSTSGGVKSALNRGRAKLAALPAQPVAAP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCCCCCCCC
AHDPELERLLGRYVELFNARDWDGVRALTSADARLRVSDCYNGLLSDSPYFVEYDRGEPW
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEECCCCCC
RMRPDTIEGEAVLVVDRLHGEVWRPAYFVRIHADGGIINRIADYYACPWILEMVAADG
CCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRIEPRLDPEGLFDMRYRAFLETVSHLRVRLHRYCARMTGSALDGEDIMQEALFEAYRK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IGLLDDTQALRPWLFRIAHNRCIDFIRTRRTRLKAEAGYASDEIVLPVEPAGPGAGRAIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHH
RLVVHLPPKERACVLLKDVFDHSLEEIAGLVGSTSGGVKSALNRGRAKLAALPAQPVAAP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCCCCCCCC
AHDPELERLLGRYVELFNARDWDGVRALTSADARLRVSDCYNGLLSDSPYFVEYDRGEPW
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEECCCCCC
RMRPDTIEGEAVLVVDRLHGEVWRPAYFVRIHADGGIINRIADYYACPWILEMVAADG
CCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]