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The map label for this gene is serB [C]

Identifier: 13471469

GI number: 13471469

Start: 1208839

End: 1209849

Strand: Direct

Name: serB [C]

Synonym: mlr1449

Alternate gene names: 13471469

Gene position: 1208839-1209849 (Clockwise)

Preceding gene: 13471466

Following gene: 13471470

Centisome position: 17.18

GC content: 66.47

Gene sequence:

>1011_bases
ATGACGCCGCCTGCGCGCTCGGCCAAGTCCAGCGCCAGTGCCGACTTGCCGCTGGCGGTTGGCCCGGCTATCAGGATCGC
ATTCTTCACGCGGCCTTCGCCCGCATCCGCGCCGGAATTCTCGATGCCGCTCATTGCCACGCTTGTTTCCCGTCCCGCTG
ACCGCGCTCTGTCGCCGTCACTTGCGAATATGGCCTCGCGTTCGGTGGGCGCAAGCACTGTCGTCTGGCTGGCCGAAGGC
ATTGCCTGCGATCTTGTCCTGCCGCAAGAGGCTGACACCGCCAATACCACGGCTGCCCTGCGCGCCGCATTGGCCGCGGA
ACCGGTCGATGTGATCGTCCAGCAGGCCCAAACGCGACGCAAGAAAATCCTCATCGCCGACATGGATTCGACCATGATCG
ACCAGGAATGCATCGACGAACTGGCCGACGAGATCGGCGTCAAGGAGCACGTCGCGGCGATCACCGCGCGATCGATGAAT
GGCGAGATCGCCTTCGAACCGGCCTTGCGCGAACGCGTCGCGCTGTTGAAGGGGCTCGATGCCGCCGTCGTCGACCGCAT
CGTCGCCAATCGGCTGACATTGGCCTCGGGTGGCCGCGCGCTGGTCCAGACCATGCGCGCCAATGGCGCCTGGGCGGCGC
TCGTCTCGGGCGGCTTCGAGGTCTTCACGACGCGCATCGCGGCCATGCTCGGCTTTCAGGAGAACCGCGCCAACCGCCTG
CTCGAACAGGATGGACGTTTCACCGGCCTGGTCGGCGAGCCGATCCTCGGCCGCGCCGCCAAGGCAGAGGCGCTGCTGGA
AATTTCCGCACGGCTTGGCCTGACGCCGGCCGACGCCATCGCCGTCGGCGATGGCGCCAATGACCTCGACATGATCCGCC
TCGCCGGCACCGGCGTGGCGCTTCACGCCAAGCCGACCGTGGCGGCGCAGGCCAAGGTTCGCATCGACCATGGCGACCTC
ACGGCACTGCTCTATCTGCAGGGCTATCGCCAGGAAGAGTTCGTCCAATGA

Upstream 100 bases:

>100_bases
GCCGTAGAGAAAATGCGGCACGCGTGCGAGATCGGCCGCTTCCGGCCGGGCGGTCAGCACGTCGAGCACCGAATAGCCCT
GCATGGAATCGCTGTTAACG

Downstream 100 bases:

>100_bases
AACCCATGCGCACCGAGCGCCTCATCCTGCGCAATTGGGAAGAGCGCGACCGCGAGCTCTTCCATCGCATCAATTCCGAC
GAGCGCGTCATGGAATTCTT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTPPARSAKSSASADLPLAVGPAIRIAFFTRPSPASAPEFSMPLIATLVSRPADRALSPSLANMASRSVGASTVVWLAEG
IACDLVLPQEADTANTTAALRAALAAEPVDVIVQQAQTRRKKILIADMDSTMIDQECIDELADEIGVKEHVAAITARSMN
GEIAFEPALRERVALLKGLDAAVVDRIVANRLTLASGGRALVQTMRANGAWAALVSGGFEVFTTRIAAMLGFQENRANRL
LEQDGRFTGLVGEPILGRAAKAEALLEISARLGLTPADAIAVGDGANDLDMIRLAGTGVALHAKPTVAAQAKVRIDHGDL
TALLYLQGYRQEEFVQ

Sequences:

>Translated_336_residues
MTPPARSAKSSASADLPLAVGPAIRIAFFTRPSPASAPEFSMPLIATLVSRPADRALSPSLANMASRSVGASTVVWLAEG
IACDLVLPQEADTANTTAALRAALAAEPVDVIVQQAQTRRKKILIADMDSTMIDQECIDELADEIGVKEHVAAITARSMN
GEIAFEPALRERVALLKGLDAAVVDRIVANRLTLASGGRALVQTMRANGAWAALVSGGFEVFTTRIAAMLGFQENRANRL
LEQDGRFTGLVGEPILGRAAKAEALLEISARLGLTPADAIAVGDGANDLDMIRLAGTGVALHAKPTVAAQAKVRIDHGDL
TALLYLQGYRQEEFVQ
>Mature_335_residues
TPPARSAKSSASADLPLAVGPAIRIAFFTRPSPASAPEFSMPLIATLVSRPADRALSPSLANMASRSVGASTVVWLAEGI
ACDLVLPQEADTANTTAALRAALAAEPVDVIVQQAQTRRKKILIADMDSTMIDQECIDELADEIGVKEHVAAITARSMNG
EIAFEPALRERVALLKGLDAAVVDRIVANRLTLASGGRALVQTMRANGAWAALVSGGFEVFTTRIAAMLGFQENRANRLL
EQDGRFTGLVGEPILGRAAKAEALLEISARLGLTPADAIAVGDGANDLDMIRLAGTGVALHAKPTVAAQAKVRIDHGDLT
ALLYLQGYRQEEFVQ

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=168, Percent_Identity=31.547619047619, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790849, Length=206, Percent_Identity=42.2330097087379, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI115534456, Length=208, Percent_Identity=28.3653846153846, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534454, Length=208, Percent_Identity=28.3653846153846, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534458, Length=210, Percent_Identity=27.6190476190476, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321647, Length=228, Percent_Identity=37.280701754386, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24661601, Length=187, Percent_Identity=31.0160427807487, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35338; Mature: 35207

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPARSAKSSASADLPLAVGPAIRIAFFTRPSPASAPEFSMPLIATLVSRPADRALSPS
CCCCCCCCCCCCCCCCCEEECCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCH
LANMASRSVGASTVVWLAEGIACDLVLPQEADTANTTAALRAALAAEPVDVIVQQAQTRR
HHHHHHHCCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
KKILIADMDSTMIDQECIDELADEIGVKEHVAAITARSMNGEIAFEPALRERVALLKGLD
HEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCC
AAVVDRIVANRLTLASGGRALVQTMRANGAWAALVSGGFEVFTTRIAAMLGFQENRANRL
HHHHHHHHHHHHEECCCCHHHHHHHHCCCCEEEEHHCCHHHHHHHHHHHHCCHHHHHHHH
LEQDGRFTGLVGEPILGRAAKAEALLEISARLGLTPADAIAVGDGANDLDMIRLAGTGVA
HHHCCCEEEECCCCHHCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCEEEEEECCCEE
LHAKPTVAAQAKVRIDHGDLTALLYLQGYRQEEFVQ
EECCCCEEEEEEEEEECCCEEEEEEECCCCHHHCCC
>Mature Secondary Structure 
TPPARSAKSSASADLPLAVGPAIRIAFFTRPSPASAPEFSMPLIATLVSRPADRALSPS
CCCCCCCCCCCCCCCCEEECCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCH
LANMASRSVGASTVVWLAEGIACDLVLPQEADTANTTAALRAALAAEPVDVIVQQAQTRR
HHHHHHHCCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
KKILIADMDSTMIDQECIDELADEIGVKEHVAAITARSMNGEIAFEPALRERVALLKGLD
HEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCC
AAVVDRIVANRLTLASGGRALVQTMRANGAWAALVSGGFEVFTTRIAAMLGFQENRANRL
HHHHHHHHHHHHEECCCCHHHHHHHHCCCCEEEEHHCCHHHHHHHHHHHHCCHHHHHHHH
LEQDGRFTGLVGEPILGRAAKAEALLEISARLGLTPADAIAVGDGANDLDMIRLAGTGVA
HHHCCCEEEECCCCHHCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCEEEEEECCCEE
LHAKPTVAAQAKVRIDHGDLTALLYLQGYRQEEFVQ
EECCCCEEEEEEEEEECCCEEEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]