Click here to switch to the map view.

The map label for this gene is cobM [H]

Identifier: 13471419

GI number: 13471419

Start: 1160231

End: 1160995

Strand: Direct

Name: cobM [H]

Synonym: mlr1385

Alternate gene names: 13471419

Gene position: 1160231-1160995 (Clockwise)

Preceding gene: 13471418

Following gene: 13471420

Centisome position: 16.49

GC content: 65.49

Gene sequence:

>765_bases
ATGACCGTTCATTTCATCGGCGCCGGTCCGGGTGCCGCCGACCTCATCACGCTGCGCGGCGCCAGGCTGCTGGCAAGCTG
CCCGGTCTGTCTGCATGCCGGCTCAATCGTCGCGCCTGAATTGCTGCAGCATTGCGCGCCGGGGACGAAACTGATCGACA
CCGCGCCGATGTCGCTCGACGAGATCGAGGCGGCCTATGTCGACGCTCACAAATCAGGCCATGATGTCGCCCGCCTGCAT
TCCGGCGACCTGTCGGTGTGGAGCGCCGTTGCCGAACAGATCCGCCGGCTGGAAAAGCACGACATACCCTACACGCTGAC
GCCAGGCGTCCCTTCCTTCGCCGCCGCCGCCGCAGCACTTCGCCTCGAGCTGACCATTCCCGAAGTCGCGCAAAGCCTGG
TGCTGACCCGCGTTTCCGGACGTGCTTCAAAAATGCCGCCCGGCGAAACGCTGGCCGGCTTCGGCCGCACCGGCGCCACG
CTCGCCATCCATCTTGCCATCCACGCAATCGACCGCGTCGTCGCCGAATTGACGCCGCATTATGGCGGCGATTGTCCGGT
GGCGATCGTCTTCCGCGCCTCCTGGCCGGACGAGCGGGTGCTGACCGGTACGCTGGAAACGATCGAGGCGCAGCTGGCCG
CCGATCCGATGGAGCGCACCGCGATTATCTTCGTCGGCCGCTCGCTGGCGGCGGAAGGTTTTGGCGAAAGTTCATTGTAC
GACGCCCACTATCAGCGGCGTTTTCGCGGACGGGACGGATTGTGA

Upstream 100 bases:

>100_bases
CATCTGCCCTTGCGGTAGCCGGTGCCGGCGCAAAACTGCTTGGTCCCCGCATTGTGCTTGGCCCGGTCACCTGTGCCATC
GCCATCAGCGGAGACGCGCC

Downstream 100 bases:

>100_bases
GCGGCACCAGCAAAAACAATGGCGGCAACGCCACGCTCGAACAGGCGCTCGCCCGGCTGAACTTCAAGCCGCGCCCGCTG
GAGCCGGGCCATGTCTGGCT

Product: precorrin 3 methylase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTVHFIGAGPGAADLITLRGARLLASCPVCLHAGSIVAPELLQHCAPGTKLIDTAPMSLDEIEAAYVDAHKSGHDVARLH
SGDLSVWSAVAEQIRRLEKHDIPYTLTPGVPSFAAAAAALRLELTIPEVAQSLVLTRVSGRASKMPPGETLAGFGRTGAT
LAIHLAIHAIDRVVAELTPHYGGDCPVAIVFRASWPDERVLTGTLETIEAQLAADPMERTAIIFVGRSLAAEGFGESSLY
DAHYQRRFRGRDGL

Sequences:

>Translated_254_residues
MTVHFIGAGPGAADLITLRGARLLASCPVCLHAGSIVAPELLQHCAPGTKLIDTAPMSLDEIEAAYVDAHKSGHDVARLH
SGDLSVWSAVAEQIRRLEKHDIPYTLTPGVPSFAAAAAALRLELTIPEVAQSLVLTRVSGRASKMPPGETLAGFGRTGAT
LAIHLAIHAIDRVVAELTPHYGGDCPVAIVFRASWPDERVLTGTLETIEAQLAADPMERTAIIFVGRSLAAEGFGESSLY
DAHYQRRFRGRDGL
>Mature_253_residues
TVHFIGAGPGAADLITLRGARLLASCPVCLHAGSIVAPELLQHCAPGTKLIDTAPMSLDEIEAAYVDAHKSGHDVARLHS
GDLSVWSAVAEQIRRLEKHDIPYTLTPGVPSFAAAAAALRLELTIPEVAQSLVLTRVSGRASKMPPGETLAGFGRTGATL
AIHLAIHAIDRVVAELTPHYGGDCPVAIVFRASWPDERVLTGTLETIEAQLAADPMERTAIIFVGRSLAAEGFGESSLYD
AHYQRRFRGRDGL

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=243, Percent_Identity=24.6913580246914, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322922, Length=259, Percent_Identity=23.1660231660232, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 26968; Mature: 26837

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHFIGAGPGAADLITLRGARLLASCPVCLHAGSIVAPELLQHCAPGTKLIDTAPMSLD
CEEEEEECCCCCHHEEECCCHHHHHHCCHHHCCCCCCHHHHHHHCCCCCEEEECCCCCHH
EIEAAYVDAHKSGHDVARLHSGDLSVWSAVAEQIRRLEKHDIPYTLTPGVPSFAAAAAAL
HHHHHHHHCCCCCCCEEEHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHH
RLELTIPEVAQSLVLTRVSGRASKMPPGETLAGFGRTGATLAIHLAIHAIDRVVAELTPH
EEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
YGGDCPVAIVFRASWPDERVLTGTLETIEAQLAADPMERTAIIFVGRSLAAEGFGESSLY
CCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCHHH
DAHYQRRFRGRDGL
HHHHHHHHCCCCCC
>Mature Secondary Structure 
TVHFIGAGPGAADLITLRGARLLASCPVCLHAGSIVAPELLQHCAPGTKLIDTAPMSLD
EEEEEECCCCCHHEEECCCHHHHHHCCHHHCCCCCCHHHHHHHCCCCCEEEECCCCCHH
EIEAAYVDAHKSGHDVARLHSGDLSVWSAVAEQIRRLEKHDIPYTLTPGVPSFAAAAAAL
HHHHHHHHCCCCCCCEEEHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHH
RLELTIPEVAQSLVLTRVSGRASKMPPGETLAGFGRTGATLAIHLAIHAIDRVVAELTPH
EEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
YGGDCPVAIVFRASWPDERVLTGTLETIEAQLAADPMERTAIIFVGRSLAAEGFGESSLY
CCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCHHH
DAHYQRRFRGRDGL
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]