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The map label for this gene is qoxC [H]

Identifier: 13471153

GI number: 13471153

Start: 877804

End: 878523

Strand: Direct

Name: qoxC [H]

Synonym: mlr1043

Alternate gene names: 13471153

Gene position: 877804-878523 (Clockwise)

Preceding gene: 13471152

Following gene: 13471154

Centisome position: 12.48

GC content: 59.58

Gene sequence:

>720_bases
ATGGCAGAGACACTGACGCATATCGGCCAGACGGAGCCACGGCCCACAGGCTGGCGAGGCATTGCCGCCGATTGGTCCTC
GGATCAGCGTGCGTTCAAGAACGTGTCCTGGGGCAAGGCCATGATGTGGATCTTCCTGCTCAGCGACACCTTCATCTTCG
GTTGCTTCCTGCTCGCCTACATGACCGCGCGCATTTCGACACGCGAGCCGTGGCCCAATCCGAGCGAGGTCTTTGCGCTG
CGTATCGGCGGCTCGGAAATCCCGCTGATCCTTATTGCCATCATGACCTTCGTGCTGATCTCAAGCAGCGGGACGATGGC
CATGGCGGTCAATTTCGGCTATCGCCGCGACCGCCGCAAGACGGCAATCCTCATGCTTCTGACCGCGGCACTTGGCGCGA
CCTTTGTCGGCATGCAAGCCTTCGAATGGACCAAGCTGATCACCGAAGGGGTACGGCCCTGGGGCAATCCCTGGGGTGCT
GCACAATTCGGCTCGTCTTTCTTCATGATCACCGGTTTCCACGGCACCCATGTGACGATCGGGGTGATCTTCCTGATCAT
CGTGGCGCGAAAGGTCTGGCGCGGAGATTTCGACACCGGACGGCGCGGTTTCTTCACCAGCCGCAAGGGCCGCTACGAGA
ACGTCGAGATCATGGGGCTGTATTGGCACTTCGTCGACCTGGTCTGGGTGTTCATCTTCGCTTTCTTCTATCTTTGGTGA

Upstream 100 bases:

>100_bases
CTGCTTTTCGTCTGGCTTGCCATCTTCGCGCTGCTAGCCGGCTGGGCCGCGACGTTCATCGACATTTGCCGGCAGTTGCT
GACTTAAGGGGATCAAGCGA

Downstream 100 bases:

>100_bases
GAGGCAGACATGGCTGAAGCAACCGCAAACGGCCTCGGACAACACGCACTTCATGCTGGTCATGCACATGAAGCGCCGGC
CGCCGCCGCCCGTGCCGACG

Product: cytochrome c oxidase subunit III

Products: ferricytochrome c; H2O

Alternate protein names: Quinol oxidase polypeptide III [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MAETLTHIGQTEPRPTGWRGIAADWSSDQRAFKNVSWGKAMMWIFLLSDTFIFGCFLLAYMTARISTREPWPNPSEVFAL
RIGGSEIPLILIAIMTFVLISSSGTMAMAVNFGYRRDRRKTAILMLLTAALGATFVGMQAFEWTKLITEGVRPWGNPWGA
AQFGSSFFMITGFHGTHVTIGVIFLIIVARKVWRGDFDTGRRGFFTSRKGRYENVEIMGLYWHFVDLVWVFIFAFFYLW

Sequences:

>Translated_239_residues
MAETLTHIGQTEPRPTGWRGIAADWSSDQRAFKNVSWGKAMMWIFLLSDTFIFGCFLLAYMTARISTREPWPNPSEVFAL
RIGGSEIPLILIAIMTFVLISSSGTMAMAVNFGYRRDRRKTAILMLLTAALGATFVGMQAFEWTKLITEGVRPWGNPWGA
AQFGSSFFMITGFHGTHVTIGVIFLIIVARKVWRGDFDTGRRGFFTSRKGRYENVEIMGLYWHFVDLVWVFIFAFFYLW
>Mature_238_residues
AETLTHIGQTEPRPTGWRGIAADWSSDQRAFKNVSWGKAMMWIFLLSDTFIFGCFLLAYMTARISTREPWPNPSEVFALR
IGGSEIPLILIAIMTFVLISSSGTMAMAVNFGYRRDRRKTAILMLLTAALGATFVGMQAFEWTKLITEGVRPWGNPWGAA
QFGSSFFMITGFHGTHVTIGVIFLIIVARKVWRGDFDTGRRGFFTSRKGRYENVEIMGLYWHFVDLVWVFIFAFFYLW

Specific function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water [H]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=155, Percent_Identity=32.9032258064516, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786633, Length=196, Percent_Identity=30.6122448979592, Blast_Score=91, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014246
- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: 1.9.3.1

Molecular weight: Translated: 27275; Mature: 27144

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETLTHIGQTEPRPTGWRGIAADWSSDQRAFKNVSWGKAMMWIFLLSDTFIFGCFLLAY
CCCHHHHCCCCCCCCCCCCCEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
MTARISTREPWPNPSEVFALRIGGSEIPLILIAIMTFVLISSSGTMAMAVNFGYRRDRRK
HHHHCCCCCCCCCHHHEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
TAILMLLTAALGATFVGMQAFEWTKLITEGVRPWGNPWGAAQFGSSFFMITGFHGTHVTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEEECCCCHHHH
GVIFLIIVARKVWRGDFDTGRRGFFTSRKGRYENVEIMGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AETLTHIGQTEPRPTGWRGIAADWSSDQRAFKNVSWGKAMMWIFLLSDTFIFGCFLLAY
CCHHHHCCCCCCCCCCCCCEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
MTARISTREPWPNPSEVFALRIGGSEIPLILIAIMTFVLISSSGTMAMAVNFGYRRDRRK
HHHHCCCCCCCCCHHHEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
TAILMLLTAALGATFVGMQAFEWTKLITEGVRPWGNPWGAAQFGSSFFMITGFHGTHVTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEEECCCCHHHH
GVIFLIIVARKVWRGDFDTGRRGFFTSRKGRYENVEIMGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrocytochrome c; O2

Specific reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA