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The map label for this gene is ccpA [H]

Identifier: 13471133

GI number: 13471133

Start: 845156

End: 846178

Strand: Direct

Name: ccpA [H]

Synonym: mlr1020

Alternate gene names: 13471133

Gene position: 845156-846178 (Clockwise)

Preceding gene: 13471121

Following gene: 13471136

Centisome position: 12.01

GC content: 60.61

Gene sequence:

>1023_bases
ATGGATATCGAGGATGGCGGAGCAAAGCTGATTGACGTGGCCAGGCTTGCGAACTGTTCGCCGGCCACCGTCTCCCGCGT
GCTCAACGGCAATCCCAACGTGAACGAGGTCGTGCGGGATCGTGTTGTCCGGGCGGCGCGTGATCTCGGCTACGTGCCCA
ATGGTTCCGCCAGAGCTCTGCGGTCGACCCGGACAAGGTTAGTCGGCGCGATCATCCCCACATTGGACCACGCTATCTAC
GCCACGATGGTCGATGGACTTCAGGCGCGGCTTTCCGAAAAAGATGTTTCGCTCATCATCAACACCTCGGGCTACGATAT
CGAACTTGAATACGAGCAGGCACGTCTGCTGGTCGAGCGCGGGGTCGAATCAGTGGTGCTTGTCGGGTCAACGCACCGGC
CAGCCACTCTGGCCATGTTCGAAAAGAAGCGCATCAACTATGTCTACACCTACACGTCGACGGCGACGGCGGCAGGTGCG
GCCGTGGGGTTCGACAACGAAAAGGCAGGGCGAACCGCCGCCCGTTACTTGCTCGACCTCGGGCACACCAAATTCGCAAT
GATCGCCGGCATCACCCAGGACAATGATCGCGCGGCAGGTCGCCGCGACGGTTTCTTGAACGAACTCGAACGATCCGGCA
TCGATCAAGGCATGGTTCCGGTCGTCGAGGGAGCCTACAGGCTGGATGACGGCCGCACCTGCATGCGGCGGCTGATGGAA
GCCCCCCGAAGACCAACCGCGGTATTTTGCGGCAGTGATATCCTTGCCGCCGGCGCCATCAAGTACTGCCACGCCGAAGG
CATCGCAGTCCCGCAGGAGGTTTCGGTTGTCGGATTCGACAATCTGGAGATTGCAGAATTGACCTCGCCCGAACTGACCA
CATTGGAGGTGCCCGCGCGCGACATGGGCCGGATTGCCGCCGACTACATCCTGGCCTCACCATCGCAGCGACTGCATCTC
AGACAACGGGAACTGTCCATTAGGCTGATTGTCAGGGGAAGCACGGCTGTCGTGAGACGCTAA

Upstream 100 bases:

>100_bases
CAATTTGAAAGGCTTTGTCAAAGAAAGATGGTGTAGCCTTCAGAAAAGAAGTGTGTCATTAGGAAAACGGTTTCTCGAAA
ACCGTCGGATTCGAGGCTCA

Downstream 100 bases:

>100_bases
CAACATGTCGGTCGCGTGAGCCATACCTATCCTGAGGCGATTGGACCGAATGACCGCTAGGGGGCCGCTAGCGGACTGTC
TGCTTATGGGGCGAAATCGC

Product: glucose-resistance amylase regulator

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDIEDGGAKLIDVARLANCSPATVSRVLNGNPNVNEVVRDRVVRAARDLGYVPNGSARALRSTRTRLVGAIIPTLDHAIY
ATMVDGLQARLSEKDVSLIINTSGYDIELEYEQARLLVERGVESVVLVGSTHRPATLAMFEKKRINYVYTYTSTATAAGA
AVGFDNEKAGRTAARYLLDLGHTKFAMIAGITQDNDRAAGRRDGFLNELERSGIDQGMVPVVEGAYRLDDGRTCMRRLME
APRRPTAVFCGSDILAAGAIKYCHAEGIAVPQEVSVVGFDNLEIAELTSPELTTLEVPARDMGRIAADYILASPSQRLHL
RQRELSIRLIVRGSTAVVRR

Sequences:

>Translated_340_residues
MDIEDGGAKLIDVARLANCSPATVSRVLNGNPNVNEVVRDRVVRAARDLGYVPNGSARALRSTRTRLVGAIIPTLDHAIY
ATMVDGLQARLSEKDVSLIINTSGYDIELEYEQARLLVERGVESVVLVGSTHRPATLAMFEKKRINYVYTYTSTATAAGA
AVGFDNEKAGRTAARYLLDLGHTKFAMIAGITQDNDRAAGRRDGFLNELERSGIDQGMVPVVEGAYRLDDGRTCMRRLME
APRRPTAVFCGSDILAAGAIKYCHAEGIAVPQEVSVVGFDNLEIAELTSPELTTLEVPARDMGRIAADYILASPSQRLHL
RQRELSIRLIVRGSTAVVRR
>Mature_340_residues
MDIEDGGAKLIDVARLANCSPATVSRVLNGNPNVNEVVRDRVVRAARDLGYVPNGSARALRSTRTRLVGAIIPTLDHAIY
ATMVDGLQARLSEKDVSLIINTSGYDIELEYEQARLLVERGVESVVLVGSTHRPATLAMFEKKRINYVYTYTSTATAAGA
AVGFDNEKAGRTAARYLLDLGHTKFAMIAGITQDNDRAAGRRDGFLNELERSGIDQGMVPVVEGAYRLDDGRTCMRRLME
APRRPTAVFCGSDILAAGAIKYCHAEGIAVPQEVSVVGFDNLEIAELTSPELTTLEVPARDMGRIAADYILASPSQRLHL
RQRELSIRLIVRGSTAVVRR

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=332, Percent_Identity=31.6265060240964, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=30.3951367781155, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1790369, Length=334, Percent_Identity=28.4431137724551, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI48994940, Length=306, Percent_Identity=28.1045751633987, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788474, Length=332, Percent_Identity=27.710843373494, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789068, Length=307, Percent_Identity=27.6872964169381, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789202, Length=291, Percent_Identity=29.8969072164948, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790715, Length=311, Percent_Identity=25.08038585209, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=23.8993710691824, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787906, Length=330, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790689, Length=319, Percent_Identity=25.3918495297806, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786540, Length=307, Percent_Identity=25.7328990228013, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789456, Length=307, Percent_Identity=25.4071661237785, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37027; Mature: 37027

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIEDGGAKLIDVARLANCSPATVSRVLNGNPNVNEVVRDRVVRAARDLGYVPNGSARAL
CCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
RSTRTRLVGAIIPTLDHAIYATMVDGLQARLSEKDVSLIINTSGYDIELEYEQARLLVER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHHHHHHHHHC
GVESVVLVGSTHRPATLAMFEKKRINYVYTYTSTATAAGAAVGFDNEKAGRTAARYLLDL
CCCEEEEEECCCCCEEHHHHHHCCCCEEEEEECCCHHCCEEECCCCCHHHHHHHHHHHHC
GHTKFAMIAGITQDNDRAAGRRDGFLNELERSGIDQGMVPVVEGAYRLDDGRTCMRRLME
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHCCCEEECCCHHHHHHHHH
APRRPTAVFCGSDILAAGAIKYCHAEGIAVPQEVSVVGFDNLEIAELTSPELTTLEVPAR
CCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCCEEEECCCH
DMGRIAADYILASPSQRLHLRQRELSIRLIVRGSTAVVRR
HHHHHHHHHHHCCCCHHHHHHHCCEEEEEEEECCHHHHCC
>Mature Secondary Structure
MDIEDGGAKLIDVARLANCSPATVSRVLNGNPNVNEVVRDRVVRAARDLGYVPNGSARAL
CCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
RSTRTRLVGAIIPTLDHAIYATMVDGLQARLSEKDVSLIINTSGYDIELEYEQARLLVER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHHHHHHHHHC
GVESVVLVGSTHRPATLAMFEKKRINYVYTYTSTATAAGAAVGFDNEKAGRTAARYLLDL
CCCEEEEEECCCCCEEHHHHHHCCCCEEEEEECCCHHCCEEECCCCCHHHHHHHHHHHHC
GHTKFAMIAGITQDNDRAAGRRDGFLNELERSGIDQGMVPVVEGAYRLDDGRTCMRRLME
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHCCCEEECCCHHHHHHHHH
APRRPTAVFCGSDILAAGAIKYCHAEGIAVPQEVSVVGFDNLEIAELTSPELTTLEVPAR
CCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCCEEEECCCH
DMGRIAADYILASPSQRLHLRQRELSIRLIVRGSTAVVRR
HHHHHHHHHHHCCCCHHHHHHHCCEEEEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]