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The map label for this gene is bla [H]

Identifier: 13471048

GI number: 13471048

Start: 741372

End: 742124

Strand: Reverse

Name: bla [H]

Synonym: mll0916

Alternate gene names: 13471048

Gene position: 742124-741372 (Counterclockwise)

Preceding gene: 13471049

Following gene: 13471046

Centisome position: 10.55

GC content: 60.96

Gene sequence:

>753_bases
ATGCGCGCGCAATCTGCGCCGCTTGGGGACGTGCAGTGCACGCTGATCGCCGATGCGGCGAGCGGCAAGGTGCTTTATCA
GGACGGCACCTGCGACCAGCCGTTCAGCCCGGCCTCGACGTTCAAGGTGCCGCTTTCGCTGATCGGCTATGACGCCGGCA
TCCTGAGTGACGAGCACACGCCAAGCTGGGACTACAAACCCGAATTCAATGCGGCGAAGCGGGATCAGAAGATCGTCGAC
CCGGTGATCTGGGAAAAGGATTCGGTCCTCTGGTATTCGCGTGAAATCACCCGCAAGCTTGGACCGGAGAGCTTTGCCGG
CTATGTCTCGAAACTCGGCTATGGCAACAAGGACGTTTCCGGCAATCCCGGCAAGAATGACGGCCTGACCCATTCCTGGG
TGAACTCCTCGCTCAAGATCACGCCGGTCGAGCAGGTCGATTTCCTGCGCAAGCTGCTGGCGCGCAAGCTGCCGGTCTCG
GCCAAGGCCTACGACTTGACGTCGGCCATCATCCCGACGTTCCAGGCCGGAGGCTGGACGGTGCAAGGCAAGACCGGCAG
CACAAGGCTCGCCGACGATGCCGACAAGATCAGTGATAAGCGTTCGCTTGGCTGGTTCGTCGGCTGGGCGAAGAAGGACG
GCCAGCAGATCGTCTTTGCCCGCCTGGTTGTCGATGCTACCCGCACCGATATGCCAAAAGGCCTCAAGACGCGGGCGGCG
TTTCTTAAAGACCTGTCGCTGCTGGTGAAATGA

Upstream 100 bases:

>100_bases
CGAACACACTTCTGGAGCGAGCATCAATGCGTAACATCGACCGTCTTCCCTTTATCCTGGCTGGAGCCTCTTCCTGCTCG
CCTGGCTGCTGGGGTTCCCG

Downstream 100 bases:

>100_bases
GTCCTGGTTTCTAGGCAATTCCAAGGGAAAGCGCTACTCGCTTTTCCCGGGAAAACCGCTGCACACTTTTCCTGGAATTG
CTTAAGCGGTTCGGCGCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Penicillinase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MRAQSAPLGDVQCTLIADAASGKVLYQDGTCDQPFSPASTFKVPLSLIGYDAGILSDEHTPSWDYKPEFNAAKRDQKIVD
PVIWEKDSVLWYSREITRKLGPESFAGYVSKLGYGNKDVSGNPGKNDGLTHSWVNSSLKITPVEQVDFLRKLLARKLPVS
AKAYDLTSAIIPTFQAGGWTVQGKTGSTRLADDADKISDKRSLGWFVGWAKKDGQQIVFARLVVDATRTDMPKGLKTRAA
FLKDLSLLVK

Sequences:

>Translated_250_residues
MRAQSAPLGDVQCTLIADAASGKVLYQDGTCDQPFSPASTFKVPLSLIGYDAGILSDEHTPSWDYKPEFNAAKRDQKIVD
PVIWEKDSVLWYSREITRKLGPESFAGYVSKLGYGNKDVSGNPGKNDGLTHSWVNSSLKITPVEQVDFLRKLLARKLPVS
AKAYDLTSAIIPTFQAGGWTVQGKTGSTRLADDADKISDKRSLGWFVGWAKKDGQQIVFARLVVDATRTDMPKGLKTRAA
FLKDLSLLVK
>Mature_250_residues
MRAQSAPLGDVQCTLIADAASGKVLYQDGTCDQPFSPASTFKVPLSLIGYDAGILSDEHTPSWDYKPEFNAAKRDQKIVD
PVIWEKDSVLWYSREITRKLGPESFAGYVSKLGYGNKDVSGNPGKNDGLTHSWVNSSLKITPVEQVDFLRKLLARKLPVS
AKAYDLTSAIIPTFQAGGWTVQGKTGSTRLADDADKISDKRSLGWFVGWAKKDGQQIVFARLVVDATRTDMPKGLKTRAA
FLKDLSLLVK

Specific function: Has a broad substrate profile, hydrolyzes amoxicillin, ticarcillin, cephalothin, ceftazidime, cefotaxime, and aztreonam, but not imipenem or cephamycins [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 27413; Mature: 27413

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00337 BETA_LACTAMASE_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAQSAPLGDVQCTLIADAASGKVLYQDGTCDQPFSPASTFKVPLSLIGYDAGILSDEHT
CCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCC
PSWDYKPEFNAAKRDQKIVDPVIWEKDSVLWYSREITRKLGPESFAGYVSKLGYGNKDVS
CCCCCCCCCCCHHCCHHHHCHHHCCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCC
GNPGKNDGLTHSWVNSSLKITPVEQVDFLRKLLARKLPVSAKAYDLTSAIIPTFQAGGWT
CCCCCCCCCCHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEE
VQGKTGSTRLADDADKISDKRSLGWFVGWAKKDGQQIVFARLVVDATRTDMPKGLKTRAA
EECCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHCCCCCCHHHHHH
FLKDLSLLVK
HHHHHHHHCC
>Mature Secondary Structure
MRAQSAPLGDVQCTLIADAASGKVLYQDGTCDQPFSPASTFKVPLSLIGYDAGILSDEHT
CCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCC
PSWDYKPEFNAAKRDQKIVDPVIWEKDSVLWYSREITRKLGPESFAGYVSKLGYGNKDVS
CCCCCCCCCCCHHCCHHHHCHHHCCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCC
GNPGKNDGLTHSWVNSSLKITPVEQVDFLRKLLARKLPVSAKAYDLTSAIIPTFQAGGWT
CCCCCCCCCCHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEE
VQGKTGSTRLADDADKISDKRSLGWFVGWAKKDGQQIVFARLVVDATRTDMPKGLKTRAA
EECCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHCCCCCCHHHHHH
FLKDLSLLVK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9333046 [H]