| Definition | Mesorhizobium loti MAFF303099 chromosome, complete genome. |
|---|---|
| Accession | NC_002678 |
| Length | 7,036,071 |
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The map label for this gene is gyrB [H]
Identifier: 13471034
GI number: 13471034
Start: 724438
End: 726495
Strand: Direct
Name: gyrB [H]
Synonym: mlr0901
Alternate gene names: 13471034
Gene position: 724438-726495 (Clockwise)
Preceding gene: 13471022
Following gene: 13471035
Centisome position: 10.3
GC content: 63.51
Gene sequence:
>2058_bases ATGGACGACAACAACGACCTCTTCGGCAATATGGACAAGCAGCCGCAGCCGGTTCGCACACCGGCGCGCCCGGCCGACCC GCTTGTGCAGGCAGCAGCCAAGCGCCCGGCCGCGACCAAGGATGGCAGCGAGGGCTACAGCGCCGCCGACATCGAGGTGC TCGAAGGCCTGGAGCCGGTGCGCCGCCGGCCAGGCATGTATATTGGCGGCACCGACGACAAGGCGATGCATCACCTGTTC GCCGAGGTCATCGACAATTCGATGGACGAGGCGGTTGCCGGCCATGCCACCTTCATCGATGTCGAGCTTTCGGCCGACGG GTTTCTGACCGTTACCGACAATGGCCGCGGCATCCCGGTCGATCCGCATCCGAAATTCAAGAAGCCGGCGCTCGAAGTCA TCATGACGACGCTGCATTCGGGCGGCAAATTCGACTCCAAGGTCTATGAAACCTCCGGCGGCCTGCATGGCGTCGGCGTT TCCGTGGTCAACGCGCTGTCGGATCATCTCGAGGTCGAGGTCGCGCGTGGCCGCCAGCTCTATCGCCAGCGCTTTTCGCG CGGCATTCCGGTAAGCGGCCTAGAGCAGCTTGGCGAGGTCCATAATCGGCGCGGAACGAAAATCCGCTTCCATCCCGACG AGCAGATCTTCGGCAAGGGCGCGGCCTTCGAACCGGCGCGCCTCTACCGCATGACGCGCTCGAAAGCCTATCTGTTCGGC GGTGTCGAAATCCGCTGGACCTGCGATCCCTCGCTGATCAAGGAAAAGGACCAGACGCCGGCCAAGGCTGAGTTCCATTT CCCCGGCGGCCTGAAGGACTATCTCAAGGCATCGCTCGGCGACGACTTTCAGGTGACGCGGGAAATCTTCGCGGGAAAAA GCGAAAAGCAAGGCGGCCATGGCTCGCTCGAATGGGCGGTGACCTGGTTCGGCGGCGACGGCTTCATCAATTCCTACTGC AACACCATCCCGACCGGCGAAGGCGGTACGCACGAGGCCGGCTTCCGCAACGTGCTGACCCGGGGCTTGCGCGCCTATGC CGATCTGGTCGGCAACAAGCGCGCCTCCATCGTCACCTCCGAAGACGTCATGATCTCGGCCGCCGGCATGCTATCGGTGT TCATCCGCGAGCCTGAATTCGTTGGCCAGACCAAGGACAGGCTGGCGACGATCGAGGCAATCCGCATTGTCGAGACCGCG ATCCGCGATCCGTTCGACCATTGGCTGGCCGACAATCCGCAGGAAGCCTCGAAGCTGCTGGAATGGGTGATCGCGCGCGC CGACGAGCGGGTGCGCCGGCGCCAGGAAAAAGAAGTGTCGCGCAAGAGCGCGGTGCGCAAATTGCGCCTGCCGGGCAAGC TCGCCGACTGCACGCAGAACGCGGCGGCCGGTGCCGAACTGTTCATCGTCGAAGGTGACTCCGCCGGCGGCTCGGCCAAA CAGGCGCGCGACCGTGCCAGCCAGGCAGTACTGCCATTGCGCGGAAAAATCCTCAACGTGGCCAGTGCCGGCAATGACAA GCTGGCGGCCAACCAGCAGATATCGGACCTGATCCAGGCTCTCGGCTGCGGCACGCGCTCAAAATACCGCGACGAGGATT TGCGCTACGACCGCGTCATCATCATGACCGACGCCGACGTCGACGGCGCCCATATCGCTTCGCTGCTGATCACCTTCTTC TACCAGGAAATGCCGGCGCTGGTGCGTGGCGGCCATCTCTATCTGGCGGTGCCGCCGCTTTACTCGATCCGGCAAGGCGG CAAGGTCGCCTATGCCCGCGACGATGCGCACAAGGACGAGCTCCTGCGCACCGAATTCACCGGGCGCGGCAAGGTCGAGC TTGGCCGCTTCAAGGGCCTGGGCGAGATGATGGCCTCGCAGCTCAAGGAGACCACCATGGATCCGAGAAAGCGCACGCTG CTCAGGGTCGATGTGAACGAAATCGATTCAGCCACCAAGGACAGGGTCGATGAGCTGATGGGCACCAAGCCGGAAGCCCG CTTCCGCTTCATCCAGGAGCGTGCCGAATTCGCCGAGACGGAAGTGCTGGATATCTAG
Upstream 100 bases:
>100_bases CGGGTCAAATCCCCGAACGTAACAGGAACCTCCGTCGCTTGGCGCTGAAAAGCGTGGCAGTATCGACGGGTGATTCGCAG CACCGGACCCTATGGCAGGC
Downstream 100 bases:
>100_bases CCGCGGGCCAGTTTAGCTTGCGCTTCCGATATGGAGACCGGCACGTGACCTGGGCGCGGCTGAAAGCCTATTTCGAGACG AGCCTGGCCGGGTTGACGCA
Product: DNA topoisomerase IV subunit B
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 685; Mature: 685
Protein sequence:
>685_residues MDDNNDLFGNMDKQPQPVRTPARPADPLVQAAAKRPAATKDGSEGYSAADIEVLEGLEPVRRRPGMYIGGTDDKAMHHLF AEVIDNSMDEAVAGHATFIDVELSADGFLTVTDNGRGIPVDPHPKFKKPALEVIMTTLHSGGKFDSKVYETSGGLHGVGV SVVNALSDHLEVEVARGRQLYRQRFSRGIPVSGLEQLGEVHNRRGTKIRFHPDEQIFGKGAAFEPARLYRMTRSKAYLFG GVEIRWTCDPSLIKEKDQTPAKAEFHFPGGLKDYLKASLGDDFQVTREIFAGKSEKQGGHGSLEWAVTWFGGDGFINSYC NTIPTGEGGTHEAGFRNVLTRGLRAYADLVGNKRASIVTSEDVMISAAGMLSVFIREPEFVGQTKDRLATIEAIRIVETA IRDPFDHWLADNPQEASKLLEWVIARADERVRRRQEKEVSRKSAVRKLRLPGKLADCTQNAAAGAELFIVEGDSAGGSAK QARDRASQAVLPLRGKILNVASAGNDKLAANQQISDLIQALGCGTRSKYRDEDLRYDRVIIMTDADVDGAHIASLLITFF YQEMPALVRGGHLYLAVPPLYSIRQGGKVAYARDDAHKDELLRTEFTGRGKVELGRFKGLGEMMASQLKETTMDPRKRTL LRVDVNEIDSATKDRVDELMGTKPEARFRFIQERAEFAETEVLDI
Sequences:
>Translated_685_residues MDDNNDLFGNMDKQPQPVRTPARPADPLVQAAAKRPAATKDGSEGYSAADIEVLEGLEPVRRRPGMYIGGTDDKAMHHLF AEVIDNSMDEAVAGHATFIDVELSADGFLTVTDNGRGIPVDPHPKFKKPALEVIMTTLHSGGKFDSKVYETSGGLHGVGV SVVNALSDHLEVEVARGRQLYRQRFSRGIPVSGLEQLGEVHNRRGTKIRFHPDEQIFGKGAAFEPARLYRMTRSKAYLFG GVEIRWTCDPSLIKEKDQTPAKAEFHFPGGLKDYLKASLGDDFQVTREIFAGKSEKQGGHGSLEWAVTWFGGDGFINSYC NTIPTGEGGTHEAGFRNVLTRGLRAYADLVGNKRASIVTSEDVMISAAGMLSVFIREPEFVGQTKDRLATIEAIRIVETA IRDPFDHWLADNPQEASKLLEWVIARADERVRRRQEKEVSRKSAVRKLRLPGKLADCTQNAAAGAELFIVEGDSAGGSAK QARDRASQAVLPLRGKILNVASAGNDKLAANQQISDLIQALGCGTRSKYRDEDLRYDRVIIMTDADVDGAHIASLLITFF YQEMPALVRGGHLYLAVPPLYSIRQGGKVAYARDDAHKDELLRTEFTGRGKVELGRFKGLGEMMASQLKETTMDPRKRTL LRVDVNEIDSATKDRVDELMGTKPEARFRFIQERAEFAETEVLDI >Mature_685_residues MDDNNDLFGNMDKQPQPVRTPARPADPLVQAAAKRPAATKDGSEGYSAADIEVLEGLEPVRRRPGMYIGGTDDKAMHHLF AEVIDNSMDEAVAGHATFIDVELSADGFLTVTDNGRGIPVDPHPKFKKPALEVIMTTLHSGGKFDSKVYETSGGLHGVGV SVVNALSDHLEVEVARGRQLYRQRFSRGIPVSGLEQLGEVHNRRGTKIRFHPDEQIFGKGAAFEPARLYRMTRSKAYLFG GVEIRWTCDPSLIKEKDQTPAKAEFHFPGGLKDYLKASLGDDFQVTREIFAGKSEKQGGHGSLEWAVTWFGGDGFINSYC NTIPTGEGGTHEAGFRNVLTRGLRAYADLVGNKRASIVTSEDVMISAAGMLSVFIREPEFVGQTKDRLATIEAIRIVETA IRDPFDHWLADNPQEASKLLEWVIARADERVRRRQEKEVSRKSAVRKLRLPGKLADCTQNAAAGAELFIVEGDSAGGSAK QARDRASQAVLPLRGKILNVASAGNDKLAANQQISDLIQALGCGTRSKYRDEDLRYDRVIIMTDADVDGAHIASLLITFF YQEMPALVRGGHLYLAVPPLYSIRQGGKVAYARDDAHKDELLRTEFTGRGKVELGRFKGLGEMMASQLKETTMDPRKRTL LRVDVNEIDSATKDRVDELMGTKPEARFRFIQERAEFAETEVLDI
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the type II topoisomerase family [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=599, Percent_Identity=26.7111853088481, Blast_Score=143, Evalue=5e-34, Organism=Homo sapiens, GI19913408, Length=632, Percent_Identity=25.1582278481013, Blast_Score=130, Evalue=4e-30, Organism=Escherichia coli, GI1789408, Length=647, Percent_Identity=43.1221020092736, Blast_Score=467, Evalue=1e-132, Organism=Escherichia coli, GI48994957, Length=567, Percent_Identity=44.2680776014109, Blast_Score=439, Evalue=1e-124, Organism=Caenorhabditis elegans, GI212645845, Length=573, Percent_Identity=23.2111692844677, Blast_Score=115, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17535065, Length=580, Percent_Identity=24.4827586206897, Blast_Score=109, Evalue=4e-24, Organism=Caenorhabditis elegans, GI212645657, Length=217, Percent_Identity=26.2672811059908, Blast_Score=70, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6324241, Length=646, Percent_Identity=24.4582043343653, Blast_Score=120, Evalue=5e-28, Organism=Drosophila melanogaster, GI17136538, Length=600, Percent_Identity=23.8333333333333, Blast_Score=120, Evalue=3e-27,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR005737 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 75556; Mature: 75556
Theoretical pI: Translated: 6.73; Mature: 6.73
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDDNNDLFGNMDKQPQPVRTPARPADPLVQAAAKRPAATKDGSEGYSAADIEVLEGLEPV CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHH RRRPGMYIGGTDDKAMHHLFAEVIDNSMDEAVAGHATFIDVELSADGFLTVTDNGRGIPV HHCCCEEECCCCHHHHHHHHHHHHHCHHHHHHCCCEEEEEEEECCCCEEEECCCCCCCCC DPHPKFKKPALEVIMTTLHSGGKFDSKVYETSGGLHGVGVSVVNALSDHLEVEVARGRQL CCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHEEHHHHHHHH YRQRFSRGIPVSGLEQLGEVHNRRGTKIRFHPDEQIFGKGAAFEPARLYRMTRSKAYLFG HHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHCCEEEEE GVEIRWTCDPSLIKEKDQTPAKAEFHFPGGLKDYLKASLGDDFQVTREIFAGKSEKQGGH CEEEEEECCHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC GSLEWAVTWFGGDGFINSYCNTIPTGEGGTHEAGFRNVLTRGLRAYADLVGNKRASIVTS CCEEEEEEEECCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC EDVMISAAGMLSVFIREPEFVGQTKDRLATIEAIRIVETAIRDPFDHWLADNPQEASKLL CCCEEEHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHH EWVIARADERVRRRQEKEVSRKSAVRKLRLPGKLADCTQNAAAGAELFIVEGDSAGGSAK HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCCCCHH QARDRASQAVLPLRGKILNVASAGNDKLAANQQISDLIQALGCGTRSKYRDEDLRYDRVI HHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE IMTDADVDGAHIASLLITFFYQEMPALVRGGHLYLAVPPLYSIRQGGKVAYARDDAHKDE EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHCCCEEEEECCCHHHHH LLRTEFTGRGKVELGRFKGLGEMMASQLKETTMDPRKRTLLRVDVNEIDSATKDRVDELM HHHHHCCCCCCEEHHHHCCHHHHHHHHHHHHCCCCCHHEEEEEEHHHHCCHHHHHHHHHH GTKPEARFRFIQERAEFAETEVLDI CCCCHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MDDNNDLFGNMDKQPQPVRTPARPADPLVQAAAKRPAATKDGSEGYSAADIEVLEGLEPV CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHH RRRPGMYIGGTDDKAMHHLFAEVIDNSMDEAVAGHATFIDVELSADGFLTVTDNGRGIPV HHCCCEEECCCCHHHHHHHHHHHHHCHHHHHHCCCEEEEEEEECCCCEEEECCCCCCCCC DPHPKFKKPALEVIMTTLHSGGKFDSKVYETSGGLHGVGVSVVNALSDHLEVEVARGRQL CCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHEEHHHHHHHH YRQRFSRGIPVSGLEQLGEVHNRRGTKIRFHPDEQIFGKGAAFEPARLYRMTRSKAYLFG HHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHCCEEEEE GVEIRWTCDPSLIKEKDQTPAKAEFHFPGGLKDYLKASLGDDFQVTREIFAGKSEKQGGH CEEEEEECCHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC GSLEWAVTWFGGDGFINSYCNTIPTGEGGTHEAGFRNVLTRGLRAYADLVGNKRASIVTS CCEEEEEEEECCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEC EDVMISAAGMLSVFIREPEFVGQTKDRLATIEAIRIVETAIRDPFDHWLADNPQEASKLL CCCEEEHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHH EWVIARADERVRRRQEKEVSRKSAVRKLRLPGKLADCTQNAAAGAELFIVEGDSAGGSAK HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCCCCHH QARDRASQAVLPLRGKILNVASAGNDKLAANQQISDLIQALGCGTRSKYRDEDLRYDRVI HHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE IMTDADVDGAHIASLLITFFYQEMPALVRGGHLYLAVPPLYSIRQGGKVAYARDDAHKDE EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHCCCEEEEECCCHHHHH LLRTEFTGRGKVELGRFKGLGEMMASQLKETTMDPRKRTLLRVDVNEIDSATKDRVDELM HHHHHCCCCCCEEHHHHCCHHHHHHHHHHHHCCCCCHHEEEEEEHHHHCCHHHHHHHHHH GTKPEARFRFIQERAEFAETEVLDI CCCCHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9797224 [H]