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The map label for this gene is fabG [H]

Identifier: 13470963

GI number: 13470963

Start: 637613

End: 638392

Strand: Direct

Name: fabG [H]

Synonym: mlr0808

Alternate gene names: 13470963

Gene position: 637613-638392 (Clockwise)

Preceding gene: 13470960

Following gene: 13470964

Centisome position: 9.06

GC content: 65.9

Gene sequence:

>780_bases
ATGGATCTTGGTATCCGCGGAAAGAAGGCCATAGTCTGCGCTTCGAGCAAGGGGCTTGGAAAGGGCTGCGCCATGGCGCT
GGCCGAGGCCGGTTGCGATATCGTCGTCAACGGCCGCAACGCCGAACTGGTGGCCAAGACCGCTGCGGAGCTGCGCGAGC
GTTTTGACGTGACGGTGACGGAAGTCGTCGGCGACGTTTCGAAACCGGACGTGCAGAAGGCGCTGCTCGCCGCCTGCCCG
GAACCCGACATCCTCGTCAACAACAATGGCGGCCCGCCGCTGCGCGATTTCCGCGAACTCGATCGCGCGAAAATTCTCGA
AGGCGTGACCCAGAACATGGTGACGCCAATCGAGCTGGTGCAAGCCGTCCTCGACGGCATGGCGAAGCGTGGCTTCGGCC
GCATCGTCAACATCACCTCGCTGTCGGTCTATGTTCCTATTCCAGGTCTCGACCTGTCGTCGGGCGCGCGGGCCGGCCTG
ACCTCCTTCCTCGCGGGGGTGGCGCGGACGGTGATCGACCGCAACGTCACCATCAACAGCCTCTTGCCCGGCAAGCTCGA
CACCGACCGGCTGCGCGGCCCGCACGAGGCTGGCACATCAGAGGCCCCCGCCGCGGCAGCCGCGCGCAAGACCCGCATCA
GCGCCGATGTGCCGGCCAAGCGGCTCGGCACGCCGGAGGAATTCGGCCAGATCTGCGCCTTCCTCTGCTCGGTCCATGCC
GGCTATCTCACGGGCCAGAACATACCGGTCGATGGCGGCCTCTACGTCAGCGCCTTCTGA

Upstream 100 bases:

>100_bases
TCGCGCAGCCTATGCCCCGATTCATGCAACAACCGTATGACGGTTGCGATTGGTCCAGCCTAAGGACTAGCTTGCCGGCC
AAATCACAGGAGAAATCGTC

Downstream 100 bases:

>100_bases
CCGAGAGGTCAGCGAGGCGGCGCGACTCATCTGGCATGAAATGGCCGTAAGCATCTGACATCTAGTGATTTTCGACGCGC
CGCCACTTAAAGCTGCCGGC

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDLGIRGKKAIVCASSKGLGKGCAMALAEAGCDIVVNGRNAELVAKTAAELRERFDVTVTEVVGDVSKPDVQKALLAACP
EPDILVNNNGGPPLRDFRELDRAKILEGVTQNMVTPIELVQAVLDGMAKRGFGRIVNITSLSVYVPIPGLDLSSGARAGL
TSFLAGVARTVIDRNVTINSLLPGKLDTDRLRGPHEAGTSEAPAAAAARKTRISADVPAKRLGTPEEFGQICAFLCSVHA
GYLTGQNIPVDGGLYVSAF

Sequences:

>Translated_259_residues
MDLGIRGKKAIVCASSKGLGKGCAMALAEAGCDIVVNGRNAELVAKTAAELRERFDVTVTEVVGDVSKPDVQKALLAACP
EPDILVNNNGGPPLRDFRELDRAKILEGVTQNMVTPIELVQAVLDGMAKRGFGRIVNITSLSVYVPIPGLDLSSGARAGL
TSFLAGVARTVIDRNVTINSLLPGKLDTDRLRGPHEAGTSEAPAAAAARKTRISADVPAKRLGTPEEFGQICAFLCSVHA
GYLTGQNIPVDGGLYVSAF
>Mature_259_residues
MDLGIRGKKAIVCASSKGLGKGCAMALAEAGCDIVVNGRNAELVAKTAAELRERFDVTVTEVVGDVSKPDVQKALLAACP
EPDILVNNNGGPPLRDFRELDRAKILEGVTQNMVTPIELVQAVLDGMAKRGFGRIVNITSLSVYVPIPGLDLSSGARAGL
TSFLAGVARTVIDRNVTINSLLPGKLDTDRLRGPHEAGTSEAPAAAAARKTRISADVPAKRLGTPEEFGQICAFLCSVHA
GYLTGQNIPVDGGLYVSAF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=30.3149606299213, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=25.2830188679245, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=29.2553191489362, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7705855, Length=197, Percent_Identity=28.4263959390863, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=25, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=29.9610894941634, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082160, Length=267, Percent_Identity=28.0898876404494, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788459, Length=263, Percent_Identity=26.615969581749, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=28.4090909090909, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787905, Length=267, Percent_Identity=26.9662921348315, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=28.3464566929134, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=23.574144486692, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=24.7011952191235, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=25.8823529411765, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=25.2873563218391, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=28.3582089552239, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.4615384615385, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=29.5880149812734, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=28.2527881040892, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=27.2, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=277, Percent_Identity=29.2418772563177, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=25.9398496240602, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.9693486590038, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=28.0769230769231, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=26.0536398467433, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=26.8199233716475, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=26.8482490272374, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=28.740157480315, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=264, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=27.1317829457364, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644339, Length=266, Percent_Identity=27.4436090225564, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24639444, Length=271, Percent_Identity=27.6752767527675, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=28.8461538461538, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=27.2251308900524, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=27.2251308900524, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27063; Mature: 27063

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIRGKKAIVCASSKGLGKGCAMALAEAGCDIVVNGRNAELVAKTAAELRERFDVTVT
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCHHH
EVVGDVSKPDVQKALLAACPEPDILVNNNGGPPLRDFRELDRAKILEGVTQNMVTPIELV
HHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QAVLDGMAKRGFGRIVNITSLSVYVPIPGLDLSSGARAGLTSFLAGVARTVIDRNVTINS
HHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEC
LLPGKLDTDRLRGPHEAGTSEAPAAAAARKTRISADVPAKRLGTPEEFGQICAFLCSVHA
CCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHH
GYLTGQNIPVDGGLYVSAF
HHCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MDLGIRGKKAIVCASSKGLGKGCAMALAEAGCDIVVNGRNAELVAKTAAELRERFDVTVT
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCHHH
EVVGDVSKPDVQKALLAACPEPDILVNNNGGPPLRDFRELDRAKILEGVTQNMVTPIELV
HHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QAVLDGMAKRGFGRIVNITSLSVYVPIPGLDLSSGARAGLTSFLAGVARTVIDRNVTINS
HHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEC
LLPGKLDTDRLRGPHEAGTSEAPAAAAARKTRISADVPAKRLGTPEEFGQICAFLCSVHA
CCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHH
GYLTGQNIPVDGGLYVSAF
HHCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]