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The map label for this gene is ychM [C]

Identifier: 13470910

GI number: 13470910

Start: 578016

End: 579719

Strand: Direct

Name: ychM [C]

Synonym: mlr0734

Alternate gene names: 13470910

Gene position: 578016-579719 (Clockwise)

Preceding gene: 13470908

Following gene: 13470911

Centisome position: 8.22

GC content: 64.85

Gene sequence:

>1704_bases
ATGAGTTGGCGCCGGTGGCTGCCTTTGCAGGCTCTGAGCGGCTGGCAGTTCAGTGATCTCAACGGTGATCTGATCGCCGG
CCTGACATTGGCGGCGATCGCCATTCCCGAGCAGATGGCAACGGCCCGGCTCGGCGGCTTTGCCCCCGAAATCGGTTTTT
TCGCTTTTGTCGCCGGTTCGGTGGCGTTTGCCCTGTTCGGCGCCAATCGTCACCTCTCGGTTGGCGCGGATTCGACCATC
ACGCCGCTGTTCGCCGGCAGCCTGGCGCTGCTCGCCACATCCGGCTCGCCGCATTATCTGGCGCTGGCGGCCATGCTGGC
ACTGCTGGTCGGGCTGATCGTGACGCTCAGCGGCATCTTTCGCCTCGGCTGGATCGCCGATCTCCTGTCGGTGCCGGTTA
CGACAGGGTTCCTGGCCGGCATTGCCGTCCATATCATCGTTTCACAGATGCCCGGACTGCTCGGCCTGCCTGCCGAGAGT
GGAGAAACCTTGCGGCGTGTCGGCGAGATCGCCGGCAATCTTCATCTCACCAATCCCTGGAGCCTGGGGCTCGGCCTCGG
CGTGTTCGCGATCGTGTTCTGTTCGGAACGGATCAGCGCCCGCATCCCCGGCGCCTTGATCGGCATGGTGCTCGCCACGC
TTGCGGTCGTCGTCTTCGGCCTCAGGGATCACGGCGTCGAGGTGCTTGGCGCTCTGCCAAACGGCCTGCCGGGCGCCTAT
TTGCCGGTGGCGAGCCTCGGCGATGTGCAAGCGCTCGTTCCGCTGGCGCTTCTGATCGCCATTGTCGTCATGGTGCAGAC
GGCCGCAACCTCGCGGTCCTTCGCCTCGCAACCGGACGCCTCGCCCGACGTCAACCGCGATTTCGTCGGCGTCGGTGCCG
GCAGCATTTTGTCGAGCCTGTTCGGCGCCTTTGCTGTCAATGCCAGCCCGCCGCGCACAGCCATCGTCTCCCAATCGGGT
GGCCGCTCACAACTGTCCGGTCTCATTGCCGCGGCCATCGTGCTGGCGCTCGGTGCCTTTGGCGGCGCCCTGCTCGCCAA
TGTTCCGCAGGCCGCCTTGGCCGGCGTCCTGATGTTCGTTGCCCAGCACATATTGCGCTGGAAGGTGTTCGCCGGTGTCT
ACCGGCAGGCGCCGGTCGAATTCGTGTTGATCCTGGTCACCACGGCGGCAATCGTCGTGTTGCCGATCGCAACCGGGGTG
GCGGTGGGCATCGGCCTGTCGCTGCTGCATGGCATATGGAGCGCGACGCGCACGGAACCGATCGAGCTCGAACAGGTGCC
AGGCACGTCCGTCTGGTGGCCTCCGGCCAAGCCCAGCGCTGGCGAACAACTCCCGGGCGTGCTGGTCGCGGCCTTCCAGG
CGCCACTGTCCTTCGTCAATGCCGACCGATTCAAGCGCGGTGTTTGCGACCTTGTAGATGCCAGGGACGAAACCGTGAAG
CTGGTCGTGTTGGAGGCCAGCAACATCGTCGAAATCGACTACACCGCCGCACAGGCCCTGATCGACACCATCACCCATTG
CCGCAAGGCGGGCGCGATCTTTGCCATCGCGCGCATGGAATCGCTGCGCGCCCAGGCGGCGCTTGCGCGGTTCGGCATCG
CTGAAATGGTCGGCACGCAGCACATATTCCACAGCGTCGACGCGGCGATCAAATCGCTTGGTCCGGGCAAACAACAGCAG
CAAGAACAGGATGGAGTACCATGA

Upstream 100 bases:

>100_bases
GGATACCACTGATTGCGACGATATGGCCACGACGCTTTTCGCCGCCACAAGGCAAAAGCCGGCAATGGACCAACTTTCCC
ACGCGAAAGCCGCAAGCGCC

Downstream 100 bases:

>100_bases
TCGACCCGCGAGAACCCATTGTCACGCCGGTTCCCGTCGAGGAATTGAGGCCGACGCAGATAACGGTCGGCATGCGGGAA
GTTGCATTGAAGCGCCAGAT

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MSWRRWLPLQALSGWQFSDLNGDLIAGLTLAAIAIPEQMATARLGGFAPEIGFFAFVAGSVAFALFGANRHLSVGADSTI
TPLFAGSLALLATSGSPHYLALAAMLALLVGLIVTLSGIFRLGWIADLLSVPVTTGFLAGIAVHIIVSQMPGLLGLPAES
GETLRRVGEIAGNLHLTNPWSLGLGLGVFAIVFCSERISARIPGALIGMVLATLAVVVFGLRDHGVEVLGALPNGLPGAY
LPVASLGDVQALVPLALLIAIVVMVQTAATSRSFASQPDASPDVNRDFVGVGAGSILSSLFGAFAVNASPPRTAIVSQSG
GRSQLSGLIAAAIVLALGAFGGALLANVPQAALAGVLMFVAQHILRWKVFAGVYRQAPVEFVLILVTTAAIVVLPIATGV
AVGIGLSLLHGIWSATRTEPIELEQVPGTSVWWPPAKPSAGEQLPGVLVAAFQAPLSFVNADRFKRGVCDLVDARDETVK
LVVLEASNIVEIDYTAAQALIDTITHCRKAGAIFAIARMESLRAQAALARFGIAEMVGTQHIFHSVDAAIKSLGPGKQQQ
QEQDGVP

Sequences:

>Translated_567_residues
MSWRRWLPLQALSGWQFSDLNGDLIAGLTLAAIAIPEQMATARLGGFAPEIGFFAFVAGSVAFALFGANRHLSVGADSTI
TPLFAGSLALLATSGSPHYLALAAMLALLVGLIVTLSGIFRLGWIADLLSVPVTTGFLAGIAVHIIVSQMPGLLGLPAES
GETLRRVGEIAGNLHLTNPWSLGLGLGVFAIVFCSERISARIPGALIGMVLATLAVVVFGLRDHGVEVLGALPNGLPGAY
LPVASLGDVQALVPLALLIAIVVMVQTAATSRSFASQPDASPDVNRDFVGVGAGSILSSLFGAFAVNASPPRTAIVSQSG
GRSQLSGLIAAAIVLALGAFGGALLANVPQAALAGVLMFVAQHILRWKVFAGVYRQAPVEFVLILVTTAAIVVLPIATGV
AVGIGLSLLHGIWSATRTEPIELEQVPGTSVWWPPAKPSAGEQLPGVLVAAFQAPLSFVNADRFKRGVCDLVDARDETVK
LVVLEASNIVEIDYTAAQALIDTITHCRKAGAIFAIARMESLRAQAALARFGIAEMVGTQHIFHSVDAAIKSLGPGKQQQ
QEQDGVP
>Mature_566_residues
SWRRWLPLQALSGWQFSDLNGDLIAGLTLAAIAIPEQMATARLGGFAPEIGFFAFVAGSVAFALFGANRHLSVGADSTIT
PLFAGSLALLATSGSPHYLALAAMLALLVGLIVTLSGIFRLGWIADLLSVPVTTGFLAGIAVHIIVSQMPGLLGLPAESG
ETLRRVGEIAGNLHLTNPWSLGLGLGVFAIVFCSERISARIPGALIGMVLATLAVVVFGLRDHGVEVLGALPNGLPGAYL
PVASLGDVQALVPLALLIAIVVMVQTAATSRSFASQPDASPDVNRDFVGVGAGSILSSLFGAFAVNASPPRTAIVSQSGG
RSQLSGLIAAAIVLALGAFGGALLANVPQAALAGVLMFVAQHILRWKVFAGVYRQAPVEFVLILVTTAAIVVLPIATGVA
VGIGLSLLHGIWSATRTEPIELEQVPGTSVWWPPAKPSAGEQLPGVLVAAFQAPLSFVNADRFKRGVCDLVDARDETVKL
VVLEASNIVEIDYTAAQALIDTITHCRKAGAIFAIARMESLRAQAALARFGIAEMVGTQHIFHSVDAAIKSLGPGKQQQQ
EQDGVP

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=493, Percent_Identity=25.1521298174442, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI39752683, Length=495, Percent_Identity=25.0505050505051, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI45827802, Length=461, Percent_Identity=25.8134490238612, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI269784651, Length=494, Percent_Identity=24.2914979757085, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI4505697, Length=511, Percent_Identity=24.6575342465753, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI94721259, Length=484, Percent_Identity=25.4132231404959, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI94721255, Length=484, Percent_Identity=25.4132231404959, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI94721253, Length=484, Percent_Identity=25.2066115702479, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI94721257, Length=484, Percent_Identity=25.4132231404959, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI4557535, Length=502, Percent_Identity=23.3067729083665, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI47131207, Length=493, Percent_Identity=25.3549695740365, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI20336272, Length=493, Percent_Identity=25.3549695740365, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI16418413, Length=499, Percent_Identity=22.4448897795591, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI16418457, Length=511, Percent_Identity=22.3091976516634, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI301601599, Length=511, Percent_Identity=22.3091976516634, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI217272867, Length=499, Percent_Identity=22.4448897795591, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI100913030, Length=507, Percent_Identity=22.879684418146, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI16306483, Length=630, Percent_Identity=20, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI20336282, Length=505, Percent_Identity=20.7920792079208, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI45827804, Length=262, Percent_Identity=26.7175572519084, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI65506789, Length=557, Percent_Identity=23.6983842010772, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI262206105, Length=154, Percent_Identity=32.4675324675325, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI262206075, Length=154, Percent_Identity=32.4675324675325, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI262206069, Length=154, Percent_Identity=32.4675324675325, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI262206063, Length=154, Percent_Identity=32.4675324675325, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI301601602, Length=203, Percent_Identity=23.6453201970443, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081859, Length=414, Percent_Identity=27.0531400966184, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17566848, Length=556, Percent_Identity=25.1798561151079, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI86565215, Length=506, Percent_Identity=25.296442687747, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI86564196, Length=522, Percent_Identity=23.9463601532567, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17551690, Length=504, Percent_Identity=25.9920634920635, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17562578, Length=498, Percent_Identity=24.8995983935743, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193203292, Length=509, Percent_Identity=23.3791748526523, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI86564876, Length=413, Percent_Identity=24.455205811138, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI86565213, Length=268, Percent_Identity=26.865671641791, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323121, Length=451, Percent_Identity=22.1729490022173, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319771, Length=448, Percent_Identity=22.0982142857143, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6325260, Length=599, Percent_Identity=20.8681135225376, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19922482, Length=522, Percent_Identity=23.5632183908046, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24651449, Length=552, Percent_Identity=23.0072463768116, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24666186, Length=552, Percent_Identity=25.1811594202899, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24649801, Length=557, Percent_Identity=22.262118491921, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI85815873, Length=540, Percent_Identity=24.4444444444444, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21358229, Length=468, Percent_Identity=24.3589743589744, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21358633, Length=542, Percent_Identity=23.9852398523985, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24663084, Length=558, Percent_Identity=22.7598566308244, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357695, Length=558, Percent_Identity=22.7598566308244, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355087, Length=569, Percent_Identity=22.1441124780316, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647160, Length=569, Percent_Identity=22.1441124780316, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 58707; Mature: 58576

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWRRWLPLQALSGWQFSDLNGDLIAGLTLAAIAIPEQMATARLGGFAPEIGFFAFVAGS
CCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VAFALFGANRHLSVGADSTITPLFAGSLALLATSGSPHYLALAAMLALLVGLIVTLSGIF
HHHHHHCCCCEEECCCCCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
RLGWIADLLSVPVTTGFLAGIAVHIIVSQMPGLLGLPAESGETLRRVGEIAGNLHLTNPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEECCCH
SLGLGLGVFAIVFCSERISARIPGALIGMVLATLAVVVFGLRDHGVEVLGALPNGLPGAY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCC
LPVASLGDVQALVPLALLIAIVVMVQTAATSRSFASQPDASPDVNRDFVGVGAGSILSSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHH
FGAFAVNASPPRTAIVSQSGGRSQLSGLIAAAIVLALGAFGGALLANVPQAALAGVLMFV
HHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AQHILRWKVFAGVYRQAPVEFVLILVTTAAIVVLPIATGVAVGIGLSLLHGIWSATRTEP
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IELEQVPGTSVWWPPAKPSAGEQLPGVLVAAFQAPLSFVNADRFKRGVCDLVDARDETVK
CEEECCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LVVLEASNIVEIDYTAAQALIDTITHCRKAGAIFAIARMESLRAQAALARFGIAEMVGTQ
EEEEECCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIFHSVDAAIKSLGPGKQQQQEQDGVP
HHHHHHHHHHHHCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SWRRWLPLQALSGWQFSDLNGDLIAGLTLAAIAIPEQMATARLGGFAPEIGFFAFVAGS
CCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VAFALFGANRHLSVGADSTITPLFAGSLALLATSGSPHYLALAAMLALLVGLIVTLSGIF
HHHHHHCCCCEEECCCCCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
RLGWIADLLSVPVTTGFLAGIAVHIIVSQMPGLLGLPAESGETLRRVGEIAGNLHLTNPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEECCCH
SLGLGLGVFAIVFCSERISARIPGALIGMVLATLAVVVFGLRDHGVEVLGALPNGLPGAY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCC
LPVASLGDVQALVPLALLIAIVVMVQTAATSRSFASQPDASPDVNRDFVGVGAGSILSSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHH
FGAFAVNASPPRTAIVSQSGGRSQLSGLIAAAIVLALGAFGGALLANVPQAALAGVLMFV
HHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AQHILRWKVFAGVYRQAPVEFVLILVTTAAIVVLPIATGVAVGIGLSLLHGIWSATRTEP
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IELEQVPGTSVWWPPAKPSAGEQLPGVLVAAFQAPLSFVNADRFKRGVCDLVDARDETVK
CEEECCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LVVLEASNIVEIDYTAAQALIDTITHCRKAGAIFAIARMESLRAQAALARFGIAEMVGTQ
EEEEECCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIFHSVDAAIKSLGPGKQQQQEQDGVP
HHHHHHHHHHHHCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]