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The map label for this gene is cdd

Identifier: 13358095

GI number: 13358095

Start: 660442

End: 660837

Strand: Reverse

Name: cdd

Synonym: UU531

Alternate gene names: 13358095

Gene position: 660837-660442 (Counterclockwise)

Preceding gene: 13358096

Following gene: 13358094

Centisome position: 87.91

GC content: 27.53

Gene sequence:

>396_bases
ATGAAATATAATGATATTTATATGGGATTATTAGAGTTATTAAAAAAAAGTTATAGTCCTTATTCAAATTATCCAGTTGC
TGCTTATGTTGATACTGATTTAGGATTTATCTCTGGTGTGAATGTTGAAAATGGATCATTTGGATTAACTTCTTGTGCTG
AAAGAAATGCAATCTTTAATGCAATTGCAAATGGTGCAAAAACATTTAAAACAGTTTATATAATTACAAAAAATAATGGT
GATATTGCGAGTCCTTGTGGTGCATGTCGTCAAGTGATTTTTGAATTTTTTAAAAAGGATGCAAAAATCGTCGTTTTTAA
CAATGATGGTACTTATAAAGAATATAATGTTGAACAATTATTACCATTTGGATGAGATCCAAATATATCTCTATAG

Upstream 100 bases:

>100_bases
GATGGTTTTTTTACTCTTATCATTTATTAAAAGGTTATAACTTTTTTCAAAATGTTATAATATAGTGTTAGATATTTGTA
ACATTTGGAGTTATTGAAGT

Downstream 100 bases:

>100_bases
TTATTCATTATAAAATAAGAAAGGAGATAAAATTATGGAAAATACAAATAAAATTTTTAATTGTTGATTAAATTCACCAA
AAATTCCTCAAGTAATTAAA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKYNDIYMGLLELLKKSYSPYSNYPVAAYVDTDLGFISGVNVENGSFGLTSCAERNAIFNAIANGAKTFKTVYIITKNNG
DIASPCGACRQVIFEFFKKDAKIVVFNNDGTYKEYNVEQLLPFGWDPNISL

Sequences:

>Translated_131_residues
MKYNDIYMGLLELLKKSYSPYSNYPVAAYVDTDLGFISGVNVENGSFGLTSCAERNAIFNAIANGAKTFKTVYIITKNNG
DIASPCGACRQVIFEFFKKDAKIVVFNNDGTYKEYNVEQLLPFG*DPNISL
>Mature_131_residues
MKYNDIYMGLLELLKKSYSPYSNYPVAAYVDTDLGFISGVNVENGSFGLTSCAERNAIFNAIANGAKTFKTVYIITKNNG
DIASPCGACRQVIFEFFKKDAKIVVFNNDGTYKEYNVEQLLPFG*DPNISL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=121, Percent_Identity=41.3223140495868, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540514, Length=93, Percent_Identity=44.0860215053763, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17551074, Length=113, Percent_Identity=38.0530973451327, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323274, Length=135, Percent_Identity=37.037037037037, Blast_Score=77, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24582741, Length=94, Percent_Identity=38.2978723404255, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920920, Length=126, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582744, Length=103, Percent_Identity=32.0388349514563, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14391; Mature: 14391

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYNDIYMGLLELLKKSYSPYSNYPVAAYVDTDLGFISGVNVENGSFGLTSCAERNAIFN
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHH
AIANGAKTFKTVYIITKNNGDIASPCGACRQVIFEFFKKDAKIVVFNNDGTYKEYNVEQL
HHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECHHHC
LPFGDPNISL
CCCCCCCCCC
>Mature Secondary Structure
MKYNDIYMGLLELLKKSYSPYSNYPVAAYVDTDLGFISGVNVENGSFGLTSCAERNAIFN
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHH
AIANGAKTFKTVYIITKNNGDIASPCGACRQVIFEFFKKDAKIVVFNNDGTYKEYNVEQL
HHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECHHHC
LPFGDPNISL
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8349569 [H]