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The map label for this gene is ruvB

Identifier: 13358011

GI number: 13358011

Start: 508750

End: 509688

Strand: Reverse

Name: ruvB

Synonym: UU448

Alternate gene names: 13358011

Gene position: 509688-508750 (Counterclockwise)

Preceding gene: 13358012

Following gene: 13358008

Centisome position: 67.8

GC content: 23.96

Gene sequence:

>939_bases
ATGAAAACTAATTATGAGTTTCGTCCACAATATCTAAAAGATTTTATTGGTAAAGAACAATTAAAAAACAATTTAAAAGT
TTATTTAACTGCTAGTAAACGATTAGAAAATAGTTTTGATCATACATTATTACATGGATTATCAGGAACAGGGAAAACAA
CATTAGCACTTATAATTGCTAATGAAATGAATGTTAATTGTCACATAACACAAGGGAACTTGTTAAATAAACCTATTGAT
ATTATTAATTTATTATCTTTAATTAAAGAAAATGACGTTGTTTTTATTGATGAAATTCACGCTTGTGGTTTAGGTGCATT
TGAAACACTTTATTCTGTATTAGAAGATTTTTGTATTGATATTAATATAGGTAAAGATTTTAATTCAAAAATGACGAGGT
TAAAGATTCCTCATTTTACACTTATTGGTGCAACAACAATTTTTGGAAAAATCCCAAAATCTTTAGAAGAACGCTTCGGA
CACATCTTTCATTTAAATGAATATGAACCATCAGAAATTAGTGCAATTATTTTAAAGAATAATCAGATGCATTTTCAGAT
TGATTTAAACGAAGAAGAAATTGATTTGATTGCTAATAATGCTAAAGGAATCCCACGATTAGCAAATAGATTATTAAAAC
GAGTTGTAGATTTTAAAATTAATGGGTTTAATGATATTAAAAATATTTTTAAAAAAATTCAAATTTATGAGTTTGGATTA
GATGAACAAGATATTAATTATCTAAATGTTTTATATCGACAAGATAATGAAATTGGTTTAAAATCAATTGCACAGATTTT
ACGTTTAGATCAATATACAATTGAAACAAAAATAGAACCTTATTTAATTCAACATCATTTTATAAATAAGAATTTAAGAG
GTCGAAAAATTACAATTGAAGGAATAGATTTTTTAAAAAACAATCAACTAATCAAATAA

Upstream 100 bases:

>100_bases
GATATTGAGTATGCTATTACTAAAGTTAAAATTAATTCTCAACAAGATATTGATATTAGTGAAATTATAAGCTCTGCAAT
CAAAGAAATTTCATTGCGCC

Downstream 100 bases:

>100_bases
AAATAATTGTTTTTAACATTTTCTTTTTTTACTAATTTATTTAGTGAGATACCAATTAAACGTATTGTTTCATCTTTATA
CATTTATATTAAATGGTAGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKTNYEFRPQYLKDFIGKEQLKNNLKVYLTASKRLENSFDHTLLHGLSGTGKTTLALIIANEMNVNCHITQGNLLNKPID
IINLLSLIKENDVVFIDEIHACGLGAFETLYSVLEDFCIDINIGKDFNSKMTRLKIPHFTLIGATTIFGKIPKSLEERFG
HIFHLNEYEPSEISAIILKNNQMHFQIDLNEEEIDLIANNAKGIPRLANRLLKRVVDFKINGFNDIKNIFKKIQIYEFGL
DEQDINYLNVLYRQDNEIGLKSIAQILRLDQYTIETKIEPYLIQHHFINKNLRGRKITIEGIDFLKNNQLIK

Sequences:

>Translated_312_residues
MKTNYEFRPQYLKDFIGKEQLKNNLKVYLTASKRLENSFDHTLLHGLSGTGKTTLALIIANEMNVNCHITQGNLLNKPID
IINLLSLIKENDVVFIDEIHACGLGAFETLYSVLEDFCIDINIGKDFNSKMTRLKIPHFTLIGATTIFGKIPKSLEERFG
HIFHLNEYEPSEISAIILKNNQMHFQIDLNEEEIDLIANNAKGIPRLANRLLKRVVDFKINGFNDIKNIFKKIQIYEFGL
DEQDINYLNVLYRQDNEIGLKSIAQILRLDQYTIETKIEPYLIQHHFINKNLRGRKITIEGIDFLKNNQLIK
>Mature_312_residues
MKTNYEFRPQYLKDFIGKEQLKNNLKVYLTASKRLENSFDHTLLHGLSGTGKTTLALIIANEMNVNCHITQGNLLNKPID
IINLLSLIKENDVVFIDEIHACGLGAFETLYSVLEDFCIDINIGKDFNSKMTRLKIPHFTLIGATTIFGKIPKSLEERFG
HIFHLNEYEPSEISAIILKNNQMHFQIDLNEEEIDLIANNAKGIPRLANRLLKRVVDFKINGFNDIKNIFKKIQIYEFGL
DEQDINYLNVLYRQDNEIGLKSIAQILRLDQYTIETKIEPYLIQHHFINKNLRGRKITIEGIDFLKNNQLIK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=304, Percent_Identity=33.2236842105263, Blast_Score=184, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_UREP2 (B1AJ89)

Other databases:

- EMBL:   CP000942
- RefSeq:   YP_001752533.1
- ProteinModelPortal:   B1AJ89
- SMR:   B1AJ89
- GeneID:   6155165
- GenomeReviews:   CP000942_GR
- KEGG:   upa:UPA3_0467
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   UPAR505682:UPA3_0467-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 36106; Mature: 36106

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNYEFRPQYLKDFIGKEQLKNNLKVYLTASKRLENSFDHTLLHGLSGTGKTTLALIIA
CCCCCCCCHHHHHHHCCHHHHCCCEEEEEEECHHHCCCHHHHHHHCCCCCCCEEEEEEEE
NEMNVNCHITQGNLLNKPIDIINLLSLIKENDVVFIDEIHACGLGAFETLYSVLEDFCID
ECCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHEEE
INIGKDFNSKMTRLKIPHFTLIGATTIFGKIPKSLEERFGHIFHLNEYEPSEISAIILKN
EEECCCCCCCHHEEECCCEEEEHHHHHHHHCCHHHHHHCCCEEEECCCCCCCEEEEEEEC
NQMHFQIDLNEEEIDLIANNAKGIPRLANRLLKRVVDFKINGFNDIKNIFKKIQIYEFGL
CEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEECC
DEQDINYLNVLYRQDNEIGLKSIAQILRLDQYTIETKIEPYLIQHHFINKNLRGRKITIE
CCCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCEEEEEHHHCCCCCCCEEEEE
GIDFLKNNQLIK
CCHHHCCCCCCC
>Mature Secondary Structure
MKTNYEFRPQYLKDFIGKEQLKNNLKVYLTASKRLENSFDHTLLHGLSGTGKTTLALIIA
CCCCCCCCHHHHHHHCCHHHHCCCEEEEEEECHHHCCCHHHHHHHCCCCCCCEEEEEEEE
NEMNVNCHITQGNLLNKPIDIINLLSLIKENDVVFIDEIHACGLGAFETLYSVLEDFCID
ECCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHEEE
INIGKDFNSKMTRLKIPHFTLIGATTIFGKIPKSLEERFGHIFHLNEYEPSEISAIILKN
EEECCCCCCCHHEEECCCEEEEHHHHHHHHCCHHHHHHCCCEEEECCCCCCCEEEEEEEC
NQMHFQIDLNEEEIDLIANNAKGIPRLANRLLKRVVDFKINGFNDIKNIFKKIQIYEFGL
CEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEECC
DEQDINYLNVLYRQDNEIGLKSIAQILRLDQYTIETKIEPYLIQHHFINKNLRGRKITIE
CCCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCEEEEEHHHCCCCCCCEEEEE
GIDFLKNNQLIK
CCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA