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The map label for this gene is gpsA

Identifier: 13357943

GI number: 13357943

Start: 439539

End: 440513

Strand: Reverse

Name: gpsA

Synonym: UU382

Alternate gene names: 13357943

Gene position: 440513-439539 (Counterclockwise)

Preceding gene: 13357944

Following gene: 13357942

Centisome position: 58.6

GC content: 24.82

Gene sequence:

>975_bases
ATGAGTAAAATTTTAATTGTTGGAAGCGGAGCTTTTGGAAGTGCTTTAACACAAGTTTTAGTTTCAAATTCTCATATTGT
TGATGTTTATGGAATTAATGAAAATGAGCTTAATGATTTGAAAGAAAATCAAAAAAATAAGAAATATTTTCAGGATCAAA
AATTAGATTTACCAATTAATAATACATATTTGGATATTAATTTAGCACTTCAGAATCAATATGATTTTATCATCATTGCT
ATTCCTTCATTTGCTATTAAAAACTTTGTTGATAATATCAAAATTTTTAATTTATCAAAAACTATTGTTGTTAATGCAGC
GAAAGGATTAAATCTTGAAACAAAATCATCATGGTGTGATTATATTAAACAAAATTTAAAAATTAAAGCCTTAGTTGGAT
TAGTTGGCCCTTCATTTGCAATTGATGTTTTTTTAAAAAAACCAACAGTCGTTAATTTAGTAGGCAATAATTCAAACGCC
CTTATAAAAGTTAAAGAAGAATTTGAAAACAATTGATTTAAATGCATTTTATCTAAACAGTTTGATGCTGCTAATTATAT
TTCTTGTTTTAAAAATGCATTAGCAATAGGTTGTGGTATCATTTATGGATTACAAAATTCAAATAATTCTTTAGTAGCTT
TTTTAACTAAAGGAATCAATGAAATGCAACTAATTTTAGAGAAAATTTTTCACAAAAAAGTCAATCCGTTAGAATACTTT
TTTATTGGTGATACAATTTTAACTTGTACTGATCAAAAATCACGTAATTTTAGTTTTGGTTTACTGATTGCACAACAAGG
CGTACAAGAAGCTTTAGTAAATAAACAACAGACTATTGAAGGTTTAAATAACATCAAAGTTATTTATGAAATTATTAAAA
CAAATCAAATTAGTGCTCCACTTTTCCAAAATTTATATAAGGTAATTATTAACGCCTTAAATCCCCAGGATTTATTTGAT
AAAAGTTTTTGTTAA

Upstream 100 bases:

>100_bases
ATTGAAAATGAAATTCGTAAAGCTTTTGGATTTGATAGTGTACCAATAACATTATATTGACAAGATAAAAATAAAAAATT
ACGAGGAGAATAAAATAATA

Downstream 100 bases:

>100_bases
TGAATGATTTATTAAAAAATAAACTAAAACTGATTCCTCACAAACCTGGTTGTTATTTATGAAAAGATCAATTCAATCAA
ATTATTTACATTGGTAAAGC

Product: NAD+ dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSKILIVGSGAFGSALTQVLVSNSHIVDVYGINENELNDLKENQKNKKYFQDQKLDLPINNTYLDINLALQNQYDFIIIA
IPSFAIKNFVDNIKIFNLSKTIVVNAAKGLNLETKSSWCDYIKQNLKIKALVGLVGPSFAIDVFLKKPTVVNLVGNNSNA
LIKVKEEFENNWFKCILSKQFDAANYISCFKNALAIGCGIIYGLQNSNNSLVAFLTKGINEMQLILEKIFHKKVNPLEYF
FIGDTILTCTDQKSRNFSFGLLIAQQGVQEALVNKQQTIEGLNNIKVIYEIIKTNQISAPLFQNLYKVIINALNPQDLFD
KSFC

Sequences:

>Translated_324_residues
MSKILIVGSGAFGSALTQVLVSNSHIVDVYGINENELNDLKENQKNKKYFQDQKLDLPINNTYLDINLALQNQYDFIIIA
IPSFAIKNFVDNIKIFNLSKTIVVNAAKGLNLETKSSWCDYIKQNLKIKALVGLVGPSFAIDVFLKKPTVVNLVGNNSNA
LIKVKEEFENN*FKCILSKQFDAANYISCFKNALAIGCGIIYGLQNSNNSLVAFLTKGINEMQLILEKIFHKKVNPLEYF
FIGDTILTCTDQKSRNFSFGLLIAQQGVQEALVNKQQTIEGLNNIKVIYEIIKTNQISAPLFQNLYKVIINALNPQDLFD
KSFC
>Mature_323_residues
SKILIVGSGAFGSALTQVLVSNSHIVDVYGINENELNDLKENQKNKKYFQDQKLDLPINNTYLDINLALQNQYDFIIIAI
PSFAIKNFVDNIKIFNLSKTIVVNAAKGLNLETKSSWCDYIKQNLKIKALVGLVGPSFAIDVFLKKPTVVNLVGNNSNAL
IKVKEEFENN*FKCILSKQFDAANYISCFKNALAIGCGIIYGLQNSNNSLVAFLTKGINEMQLILEKIFHKKVNPLEYFF
IGDTILTCTDQKSRNFSFGLLIAQQGVQEALVNKQQTIEGLNNIKVIYEIIKTNQISAPLFQNLYKVIINALNPQDLFDK
SFC

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI24307999, Length=344, Percent_Identity=24.7093023255814, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790037, Length=321, Percent_Identity=25.2336448598131, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36192; Mature: 36061

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKILIVGSGAFGSALTQVLVSNSHIVDVYGINENELNDLKENQKNKKYFQDQKLDLPIN
CCEEEEEECCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCHHHHHHCCCCCCCCCC
NTYLDINLALQNQYDFIIIAIPSFAIKNFVDNIKIFNLSKTIVVNAAKGLNLETKSSWCD
CEEEEEEEEEECCCCEEEEEECHHHHHHHHCCEEEEEECEEEEEEECCCCCCCCHHHHHH
YIKQNLKIKALVGLVGPSFAIDVFLKKPTVVNLVGNNSNALIKVKEEFENNFKCILSKQF
HHHHCCEEEEEEECCCCCEEEEEEEECCEEEEEEECCCCEEEEEHHHHCCCEEEEEECCC
DAANYISCFKNALAIGCGIIYGLQNSNNSLVAFLTKGINEMQLILEKIFHKKVNPLEYFF
CHHHHHHHHHHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEE
IGDTILTCTDQKSRNFSFGLLIAQQGVQEALVNKQQTIEGLNNIKVIYEIIKTNQISAPL
ECCEEEEECCCCCCCCEEEEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCHH
FQNLYKVIINALNPQDLFDKSFC
HHHHHHHHHHCCCCHHHHHCCCC
>Mature Secondary Structure 
SKILIVGSGAFGSALTQVLVSNSHIVDVYGINENELNDLKENQKNKKYFQDQKLDLPIN
CEEEEEECCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCHHHHHHCCCCCCCCCC
NTYLDINLALQNQYDFIIIAIPSFAIKNFVDNIKIFNLSKTIVVNAAKGLNLETKSSWCD
CEEEEEEEEEECCCCEEEEEECHHHHHHHHCCEEEEEECEEEEEEECCCCCCCCHHHHHH
YIKQNLKIKALVGLVGPSFAIDVFLKKPTVVNLVGNNSNALIKVKEEFENNFKCILSKQF
HHHHCCEEEEEEECCCCCEEEEEEEECCEEEEEEECCCCEEEEEHHHHCCCEEEEEECCC
DAANYISCFKNALAIGCGIIYGLQNSNNSLVAFLTKGINEMQLILEKIFHKKVNPLEYFF
CHHHHHHHHHHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEE
IGDTILTCTDQKSRNFSFGLLIAQQGVQEALVNKQQTIEGLNNIKVIYEIIKTNQISAPL
ECCEEEEECCCCCCCCEEEEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCHH
FQNLYKVIINALNPQDLFDKSFC
HHHHHHHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12466555 [H]