Click here to switch to the map view.

The map label for this gene is asnC

Identifier: 13357925

GI number: 13357925

Start: 414766

End: 416130

Strand: Reverse

Name: asnC

Synonym: UU365

Alternate gene names: 13357925

Gene position: 416130-414766 (Counterclockwise)

Preceding gene: 13357926

Following gene: 13357924

Centisome position: 55.36

GC content: 29.74

Gene sequence:

>1365_bases
ATGCAATTAAAAATTAAAGAAATTTTTAATCAAGACTATGTAAAACTTGAAGGCCAAAAGATACAAATTAAAGCTTGAGT
TCGTTCAAACCGTGATTCAAAAAAAATTGGTTTTTTAGTTCTAAATGATGGTAGTTCTTTAACAAATTTACAAGCTGTAT
ATCGTGTTGATAAAATTGACAATTATGAAGAAATAGCTGCAGCACGAATGTGAGCCGCTGTTGTTATTGAAGGTGTAATT
AAATTAACTCCAACAGCTAAACAACCATTAGAACTAGAAGTATTAAATGCTCAAATTTTAAAACAAAGTGATGAAGATTT
TTTATTATCAAACAATGATTTAAATTTAGAAACATTGCGTTTAAATGCTCATTTAAGACCAAGAACAAATTTATTTCATG
CCATTATGAAAGTGAGGGCAACACTTGCTTTTGCAGTTCATGAATTTATGAATCAAAACGAATATAGTTGATTAGCTGCA
CCATTGTTTACAGGAAATGATGCTGAAGGAGCTGGCGAAACTTTTAGTATTCAAAAATTTGATAATGAAGAATTTTTTGG
TAAACAAACTCATTTATCTGTAACAGGTCAATTACAAGCTGAAGCATACGCACAAGCTTTTGGTAATGTTTATACATTTG
GTCCTACTTTTAGAGCTGAAAAATCTCACACAAATCGTCATTTAGCAGAATTTTGAATGATTGAACCTGAAATGGCTTTT
GTTGATTTAAAAGGTATGCAAGATATTGTTGAAGATTTAGTTAAACATGTTATTAAGGCTGTTTTAGAAAAAAATCAACA
AGAATTAGAATTTTTAGCTCAAAGAAATGATGAAAATTTAATTAAAAAACTACAAAAAGTTGTTGAGTCTAAATTTGAAC
GTATTGAATATAAAGATGCAGTTAAAATCCTAGCTGATGCTGTTAAAAATGGTCATCAATTCGAAAATAATGAAATCTTT
TTTGGAATGGATTTAGGATCAGAGCACGAAAGATACATGTGTGAAACATATCATCAAGGTCCTGTGTTCTTACAAAATTA
TCCAAAGGATATTAAAGCATTTTATATGAAATTAAACGATGATCAACAAACTGTAGCTTCAACAGATTTATTAATTCCAG
GCGTTGGCGAATTAGTGGGTGGATCACAACGTGAAGATAGTTATGAGAAACTATTAAAACGATGTCAAGAATTAAAAATG
CCAATTGAAAGTTTACAATGATATTTAGATTTACGTCGTTTCGGATATTATATGTCATCAGGTTTTGGAATTGGTTTTGA
GCGTTTAGTGATGTATGTAACAGGAGTTAATAATATTAAAGATACAATCCCATTCCCACGAAGTCATGGCCAAATTGAAT
TTTAA

Upstream 100 bases:

>100_bases
GCAATAAAAACTAATTTAAAGCGAAACTTATTAATCAATGATGTTTTGCTTTTTTATTTATATATTATTTAAAAAAGAAA
AAAAAGGTAATGATTTTATT

Downstream 100 bases:

>100_bases
AAAAAACATCTCATCATCACCTTTTTTTAGAAACATTCCTAATATTATCACTATCTTTAGAATTTTTTTAGCACTTATTT
GCATCATCTTATTATTAGTT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MQLKIKEIFNQDYVKLEGQKIQIKAWVRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKIDNYEEIAAARMWAAVVIEGVI
KLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLNLETLRLNAHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYSWLAA
PLFTGNDAEGAGETFSIQKFDNEEFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFWMIEPEMAF
VDLKGMQDIVEDLVKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVESKFERIEYKDAVKILADAVKNGHQFENNEIF
FGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQTVASTDLLIPGVGELVGGSQREDSYEKLLKRCQELKM
PIESLQWYLDLRRFGYYMSSGFGIGFERLVMYVTGVNNIKDTIPFPRSHGQIEF

Sequences:

>Translated_454_residues
MQLKIKEIFNQDYVKLEGQKIQIKA*VRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKIDNYEEIAAARM*AAVVIEGVI
KLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLNLETLRLNAHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYS*LAA
PLFTGNDAEGAGETFSIQKFDNEEFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEF*MIEPEMAF
VDLKGMQDIVEDLVKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVESKFERIEYKDAVKILADAVKNGHQFENNEIF
FGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQTVASTDLLIPGVGELVGGSQREDSYEKLLKRCQELKM
PIESLQ*YLDLRRFGYYMSSGFGIGFERLVMYVTGVNNIKDTIPFPRSHGQIEF
>Mature_454_residues
MQLKIKEIFNQDYVKLEGQKIQIKA*VRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKIDNYEEIAAARM*AAVVIEGVI
KLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLNLETLRLNAHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYS*LAA
PLFTGNDAEGAGETFSIQKFDNEEFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEF*MIEPEMAF
VDLKGMQDIVEDLVKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVESKFERIEYKDAVKILADAVKNGHQFENNEIF
FGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQTVASTDLLIPGVGELVGGSQREDSYEKLLKRCQELKM
PIESLQ*YLDLRRFGYYMSSGFGIGFERLVMYVTGVNNIKDTIPFPRSHGQIEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=438, Percent_Identity=39.4977168949772, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI4758762, Length=439, Percent_Identity=28.7015945330296, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI45439306, Length=450, Percent_Identity=24.6666666666667, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1787161, Length=446, Percent_Identity=43.2735426008969, Blast_Score=372, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71984122, Length=443, Percent_Identity=29.7968397291196, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17556372, Length=367, Percent_Identity=32.6975476839237, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17551876, Length=401, Percent_Identity=23.9401496259352, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319872, Length=487, Percent_Identity=33.4702258726899, Blast_Score=249, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6321807, Length=464, Percent_Identity=30.1724137931034, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6323011, Length=402, Percent_Identity=25.1243781094527, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19922416, Length=450, Percent_Identity=32.4444444444444, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI19921528, Length=436, Percent_Identity=30.2752293577982, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI17136276, Length=368, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 51293; Mature: 51293

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKIKEIFNQDYVKLEGQKIQIKAVRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKIDN
CCEEHHHHCCCCCEEECCCEEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
YEEIAAARMAAVVIEGVIKLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLNLETLRLN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHCCCCCEEEECCCCCEEEEEEE
AHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYSLAAPLFTGNDAEGAGETFSIQKFDNE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECEEECCCCCCCCCEEEEEECCCC
EFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFMIEPEMAFVDLK
HHCCCCEEEEEEECHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEHH
GMQDIVEDLVKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVESKFERIEYKDAVKIL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
ADAVKNGHQFENNEIFFGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQT
HHHHHCCCEECCCEEEEEECCCCCCHHHHHHHCCCCCEEECCCCHHHHHHHEEECCCHHH
VASTDLLIPGVGELVGGSQREDSYEKLLKRCQELKMPIESLQYLDLRRFGYYMSSGFGIG
HHHCCEECCCCHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
FERLVMYVTGVNNIKDTIPFPRSHGQIEF
HHHHHHHHHCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQLKIKEIFNQDYVKLEGQKIQIKAVRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKIDN
CCEEHHHHCCCCCEEECCCEEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
YEEIAAARMAAVVIEGVIKLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLNLETLRLN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHCCCCCEEEECCCCCEEEEEEE
AHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYSLAAPLFTGNDAEGAGETFSIQKFDNE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECEEECCCCCCCCCEEEEEECCCC
EFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFMIEPEMAFVDLK
HHCCCCEEEEEEECHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEHH
GMQDIVEDLVKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVESKFERIEYKDAVKIL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
ADAVKNGHQFENNEIFFGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQT
HHHHHCCCEECCCEEEEEECCCCCCHHHHHHHCCCCCEEECCCCHHHHHHHEEECCCHHH
VASTDLLIPGVGELVGGSQREDSYEKLLKRCQELKMPIESLQYLDLRRFGYYMSSGFGIG
HHHCCEECCCCHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
FERLVMYVTGVNNIKDTIPFPRSHGQIEF
HHHHHHHHHCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA