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The map label for this gene is yggB [C]

Identifier: 126699225

GI number: 126699225

Start: 1876973

End: 1877857

Strand: Direct

Name: yggB [C]

Synonym: CD1621

Alternate gene names: 126699225

Gene position: 1876973-1877857 (Clockwise)

Preceding gene: 126699224

Following gene: 126699226

Centisome position: 43.75

GC content: 30.51

Gene sequence:

>885_bases
ATGGATACGACGAAAATAGATGATATAAGCAAGTTAGATTTAAATAATTTAGACATTAATAAGATGGATATGGGAGGTAT
AATGGAAAGTCTGCTAGAATGGGCTACTACAAGCGGAGTAAAACTTATAATAGGCATACTTATACTTTCTATTGGATTTA
AAATAATAAAAAAATTTGTAAACCATGTTATGTTATTACTTAGTAAAAGAGATATTGATTTAACTTTAAGAAAGTTTTTA
AAGTCTCTTCTTTTGAGTGTACTTAAAGTTGCCGTTATAATCATTGTTCTGGAATATTGGGGAATGAGTTTGTCCAGTTT
TGCTGCTGTGATAGCATCAGCAGGGGTAGCAATAGGTTTGGCTTTACAAGGTAGTCTATCAAATTTTGCTGGAGGATTTA
TTATACTATTGATTAGACCTTTTAAAGTAGGAGATTACGTAGAAGCAGCAGGCCATGGAGGAACGGTTGAACAAATAGGT
CTTTTTTATACACAATTGGTTACTCCAGATAATAAACAGATACTTATACCTAATGGTTCTGTATCAAATGATAGTCTAAT
AAACTATTCAGCAAAGAATACTAGACGAGTTGATTTGACTTTTAGTGTAGGGTATGAAGATGATATACTACATGTTAGAA
GAGTACTTAAAGATATTGTTAATAATCATAAATTAATAATAAATGAACCAGAACCATTTATAGGAGTAGTAGAACATGGA
GATAATGCTATTAAATTTGCAACTAGAGTTTGGTGCAAGACAGAAGATTATTGGACAATTTATCTTGATTTACTAGAAGA
GGTTAAAGTTAGGTTTGACGAAGAAGGAATTACGATTCCATATCCTAAAATGGATTTAACGGTAAAAGAATTAAACAAAA
TTTAA

Upstream 100 bases:

>100_bases
TCTTGTTTACTATGTACAAATGGTATTGTATTATATTAAATAGAAAATAAGAACTTTAAACTATAATATTGGTTCTAAAA
TATAAGGTAAGGAGTTTTTT

Downstream 100 bases:

>100_bases
TTTTTTAATATAGTGTTTAAATTTAAGAATATCATATAGATATACTTATAAGGTTTGTAAAAAATTAATAAGTACTGTTA
TTTTGTAAGTAAAAATATAA

Product: mechanosensitive ion channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLIIGILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFL
KSLLLSVLKVAVIIIVLEYWGMSLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKDIVNNHKLIINEPEPFIGVVEHG
DNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEGITIPYPKMDLTVKELNKI

Sequences:

>Translated_294_residues
MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLIIGILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFL
KSLLLSVLKVAVIIIVLEYWGMSLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKDIVNNHKLIINEPEPFIGVVEHG
DNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEGITIPYPKMDLTVKELNKI
>Mature_294_residues
MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLIIGILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFL
KSLLLSVLKVAVIIIVLEYWGMSLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKDIVNNHKLIINEPEPFIGVVEHG
DNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEGITIPYPKMDLTVKELNKI

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=255, Percent_Identity=36.078431372549, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1786670, Length=244, Percent_Identity=26.2295081967213, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787591, Length=279, Percent_Identity=23.6559139784946, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI2367355, Length=289, Percent_Identity=24.5674740484429, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 32813; Mature: 32813

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS01246 UPF0003

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLIIGILILSIGFKIIKKFV
CCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
NHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGMSLSSFAAVIASAGVAIGL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHEEE
ALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIGLFYTQLVTPDNKQILIPNGS
EEECCHHHHCCCEEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEECCCC
VSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKDIVNNHKLIINEPEPFIGVVEHG
CCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECC
DNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEGITIPYPKMDLTVKELNKI
CCHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLIIGILILSIGFKIIKKFV
CCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
NHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGMSLSSFAAVIASAGVAIGL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHEEE
ALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIGLFYTQLVTPDNKQILIPNGS
EEECCHHHHCCCEEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEECCCC
VSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKDIVNNHKLIINEPEPFIGVVEHG
CCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECC
DNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEGITIPYPKMDLTVKELNKI
CCHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]