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The map label for this gene is mnaA [H]

Identifier: 126698617

GI number: 126698617

Start: 1206797

End: 1207921

Strand: Direct

Name: mnaA [H]

Synonym: CD1033

Alternate gene names: 126698617

Gene position: 1206797-1207921 (Clockwise)

Preceding gene: 126698616

Following gene: 126698618

Centisome position: 28.13

GC content: 29.51

Gene sequence:

>1125_bases
ATGAATGACATCAAGGTTATGACTGTATTTGGAACTAGACCTGAAGCTATCAAAGTAGCACCTTTAATAAAGGAACTTGA
AAAAAGAGAGAATATAAAAAGTATTGTTTGCGTTACAGCTCAACATAGAGAAATGCTTGACCAAGTTATAGAAACCTTTA
ATATAAATGTAGACTATGATTTGGATATAATGGAAAAAGGACAAAGCCTGAATGATATAACATGTAAGATTTTAAATAAA
CTTCCCTTGATTTTAAACAAGGAAAATCCAAATATAATATTGGTACATGGAGATACAACCACAACTCTAGCTACAAGTTT
GACTGCATTTTATAATAAAACTCTTGTTGGTCATATAGAAGCTGGGCTTAGAACCTATGATAAATATTCTCCTTTTCCAG
AGGAGTTAAATAGACAACTTACAGGTATTATTGCTGATATGCACTTTGCTCCTACTAATTTGGCTAGAAAAAACTTGATT
TCTGAAGGAAAACCTAATAATAATATATTTGTAACTGGTAATACTGCTATTGATGCTTTAAAGATGACAATAAAAGAAAA
CTATAATCATCCTATAATTGATGAGATTGGTAACGATAGGATGATTTTGTTAACCTCTCACAGAAGAGAAAATTTGGGTA
AACCTATGAAAAATATATTCAGAGCTATAAAGCGAATAGTAGATGACTTTGAAGATGTACAGATAGTATATCCCATACAT
TTAAATCCTAAAATACGAACTATAGCTGATGAGATATTTGGAAAATTTCCTGAAAAAATTCATATTATAGAGCCTTTAGA
TGTAGCTGATTTTCATAACTTTTTAAATAAATCTTATATGATAATGACTGATAGTGGAGGAATACAGGAAGAAGCTCCAT
CATTAGGTAAGCCAGTTCTTGTGTTGCGTGATAAAACAGAAAGAACAGAAGGAATTGAAGCAAAGACACTTAAATTAGTA
GGTACTAATGAAGATAGAATATATAATTCAGTGAGCGATTTATTAATAAATAAAGATAACTATGTTCAGATGAGTAAAGC
ATCTAATCCATATGGAGATGGAAATGCAAGCAAATATATAGTGGATATAATAATTAAAAAATTTAATTGCAAATATTTAA
ATTAG

Upstream 100 bases:

>100_bases
ACCCATCAAAAGAGAGTATAAAAGTTATTAAGTCTTGGTATGAATAATTTTGAAAGTGTAGAATTTATATAGATTAAATA
GATGATTAGGAGAGATATAA

Downstream 100 bases:

>100_bases
ATAAGGCCTAAAACATTAACTAATTGATATAAGATTTATGATAATATTAAGGAATACAATTTTTAAGGGGGAGTAATATG
GCTAGAAAATTAATAAAAAA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHREMLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNK
LPLILNKENPNIILVHGDTTTTLATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKNIFRAIKRIVDDFEDVQIVYPIH
LNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLNKSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLV
GTNEDRIYNSVSDLLINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN

Sequences:

>Translated_374_residues
MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHREMLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNK
LPLILNKENPNIILVHGDTTTTLATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKNIFRAIKRIVDDFEDVQIVYPIH
LNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLNKSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLV
GTNEDRIYNSVSDLLINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN
>Mature_374_residues
MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHREMLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNK
LPLILNKENPNIILVHGDTTTTLATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKNIFRAIKRIVDDFEDVQIVYPIH
LNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLNKSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLV
GTNEDRIYNSVSDLLINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=372, Percent_Identity=51.8817204301075, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 42489; Mature: 42489

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHREMLDQVIETFNINVDYD
CCCEEEEEEECCCCCCEEHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCC
LDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTTLATSLTAFYNKTLVGHIE
CHHHHCCCCCHHHHHHHHHCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
AGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLISEGKPNNNIFVTGNTAIDAL
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCHHHHHH
KMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKNIFRAIKRIVDDFEDVQIVYPIH
HHHHHHCCCCCCHHHCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEE
LNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLNKSYMIMTDSGGIQEEAPSLGKPVL
CCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEE
VLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDLLINKDNYVQMSKASNPYGDGNASKYI
EEECCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
VDIIIKKFNCKYLN
EEEHHHHCCCEECC
>Mature Secondary Structure
MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHREMLDQVIETFNINVDYD
CCCEEEEEEECCCCCCEEHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCC
LDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTTLATSLTAFYNKTLVGHIE
CHHHHCCCCCHHHHHHHHHCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
AGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLISEGKPNNNIFVTGNTAIDAL
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCHHHHHH
KMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKNIFRAIKRIVDDFEDVQIVYPIH
HHHHHHCCCCCCHHHCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEE
LNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLNKSYMIMTDSGGIQEEAPSLGKPVL
CCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEE
VLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDLLINKDNYVQMSKASNPYGDGNASKYI
EEECCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
VDIIIKKFNCKYLN
EEEHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]